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M. tuberculosis H37Rv Rv2585c (-)

annotation: POSSIBLE CONSERVED LIPOPROTEIN
coordinates: 2911004 - 2912677
length: 557

APRRRRHTRIAGLRVVGTATLVAATTLTACSGSAAAQIDYVVDGALVTYNTNTVIGAASAGAQAFARTLT
GFGYHGPDGQVVADRDFGTVSVVEGSPLILDYQISDDAVYSDGRPVTCDDLVLAWAAQSGRFPGFDAATQ
AGYVDIANIECTAGQKKARVSFIPDRSVVDHSQLFTATSLMPSHVIADQLHIDVTAALLSNNVSAVEQIA
RLWNSTWDLKPGRSHDEVRSRFPSSGPYKIESVLDDGAVVLVANDRWWGTKAITKRITVWPQGADIQDRV
NNRSVDVVDVAAGSSGSLVTPDSYQRTDYPSAGIEQLIFAPQGSLAQSRTRRALALCVPRDAIARDAGVP
IANSRLSPATDDALTDADGAAEARQFGRVDPAAARDALGGTPLTVRIGYGRPNARLAATIGTIADACAPA
GITVSDVTVDTPGPQALRDGKIDVLLASTGGATGSGSSGSCAMDAYDLHSGNGNNLSGYANAQIDGIISA
LAVSADPAERARLLAEAAPVLWDEMPTLPLYRQQRTLLMSTKMYAVSRNPTRWGAGWNMDRWALAR*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv2585c--100% (557)POSSIBLE CONSERVED LIPOPROTEIN
M. tuberculosis H37RvRv1280coppA1e-1423.61% (487) periplasmic oligopeptide-binding lipoprotein OppA

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2616c-0.099.82% (557) lipoprotein
M. gilvum PYR-GCKMflv_3814-0.066.23% (539) extracellular solute-binding protein
M. leprae Br4923MLBr_00489-0.078.78% (542) putative lipoprotein
M. abscessus ATCC 19977MAB_2878c-0.055.58% (556) hypothetical protein MAB_2878c
M. marinum MMMAR_2122-0.078.13% (567) ABC-type dipeptide transport system, periplasmic component
M. avium 104MAV_3466-0.076.94% (542) extracellular solute-binding protein, family protein 5
M. smegmatis MC2 155MSMEG_2963-0.065.50% (545) extracellular solute-binding protein, family protein 5
M. thermoresistible (build 8)TH_0743-0.064.53% (530) POSSIBLE CONSERVED LIPOPROTEIN
M. ulcerans Agy99MUL_1727-0.077.78% (567) ABC-type dipeptide transport system, periplasmic component
M. vanbaalenii PYR-1Mvan_2585-0.064.93% (556) extracellular solute-binding protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3814|M.gilvum_PYR-GCK          --------MAGRWRALT-----------------AVLAVVGGLGLTSCGE
Mvan_2585|M.vanbaalenii_PYR-1       --------MRRRATALT-----------------AVLALIGGLGLSSCAD
MSMEG_2963|M.smegmatis_MC2_155      -MAHRSATARARAAVVL-----------------AVLSLLAGVGLTSCGS
TH_0743|M.thermoresistible__bu      --------------VLI-----------------AVLLAVGG-GVSACGG
Rv2585c|M.tuberculosis_H37Rv        MAPRRR--RHTRIAGLR---------------VVGTATLVAATTLTACSG
Mb2616c|M.bovis_AF2122/97           MAPRRR--RHTRIAGLR---------------VVGTATLVAATTLTACSG
MMAR_2122|M.marinum_M               MASCRRERNFSRWSGLRNVLRRGFGGNGHKIAAVGVAALAAASSLSACSG
MUL_1727|M.ulcerans_Agy99           MASCRRERNFSRWSGLRNVLRRGFGGNGHKIAAVGVAALAAASSLSACSG
MLBr_00489|M.leprae_Br4923          --MRSGLFGVLRWTAVG-----------------LVATLVASLALTACSG
MAV_3466|M.avium_104                MAIRIGRRGLTGWVGIG-----------------VAVLVVAGVTLAGCAG
MAB_2878c|M.abscessus_ATCC_199      MDSRSPARTGARRIARIG--------------AIVTTVLLAAGLLTSCWT
                                                                       .    ..  ::.*  

Mflv_3814|M.gilvum_PYR-GCK          ATADSVDYAVDGVLTSYNTNTVVGAASAGPQAFARVLTGFSYHGPEGQIV
Mvan_2585|M.vanbaalenii_PYR-1       DTADAVDYAVDGTLVTYNTNTVVGAASAGPQAFARVLTGFNYHGPDGQIV
MSMEG_2963|M.smegmatis_MC2_155      GSAGEIDYAVDGTLTTYNTNTVAGAASSGPQAFARTLTGFAYHGPDGQVV
TH_0743|M.thermoresistible__bu      GTADEIDYAIDGRLTTYNTNTVAGAASGGPQAFARVLTGFHYRGPDGQII
Rv2585c|M.tuberculosis_H37Rv        SAAAQIDYVVDGALVTYNTNTVIGAASAGAQAFARTLTGFGYHGPDGQVV
Mb2616c|M.bovis_AF2122/97           SAAAQIDYVVDGALVTYNTNTVIGAASAGAQAFARTLTGFGYHGPDGQVV
MMAR_2122|M.marinum_M               SAAGQIDYVVDGPLPTYNTNTVTGAASAGAQAFARVLTGFGYHGPDGQVV
MUL_1727|M.ulcerans_Agy99           SAAGQIDYVVDGPLPTYNTNTVTGAASAGAQAFARVLTGFGYHGPDGQVV
MLBr_00489|M.leprae_Br4923          SAAGEIVYVVDGALGTYNTNTIVGAASAGAQAFARTLIGFGYHGPDGQIV
MAV_3466|M.avium_104                SAAAEIDYVVDGPLSSYNPNTVVGAASAGAQAFARTLVGFSYHGPDGQTV
MAB_2878c|M.abscessus_ATCC_199      SAAKTLDYAVDGRLTTYNVNSVAGNASAGAQAFNRVLTGFGFHGPDGQVI
                                     :*  : *.:** * :** *:: * **.*.*** *.* ** ::**:** :

Mflv_3814|M.gilvum_PYR-GCK          GDHDFGTISVVGRTPLILDYEIKPEAVYSDGKPITCDDMVLAWASQSGRF
Mvan_2585|M.vanbaalenii_PYR-1       GDHDFGTISVVGRSPLILDYEIKAEAVYSDGKPITCDDMVLAWASQSGRY
MSMEG_2963|M.smegmatis_MC2_155      ADHDFGTMSVVGRAPLVLDYVINDNAVYSDGKPITCDDMVLTWAAQSGRF
TH_0743|M.thermoresistible__bu      GDTDFGTVSVVGRSPLVLDYEINPDAVYSDGKPVTCDDMVLAWAAQSGRF
Rv2585c|M.tuberculosis_H37Rv        ADRDFGTVSVVEGSPLILDYQISDDAVYSDGRPVTCDDLVLAWAAQSGRF
Mb2616c|M.bovis_AF2122/97           ADRDFGTVSVVEGSPLILDYQISDDAVYSDGRPVTCDDLVLAWAAQSGRF
MMAR_2122|M.marinum_M               ADHDFGTISVVGGAPLVLDYQIADDAVYSDGKQVTCDDLVLAWAAESGRY
MUL_1727|M.ulcerans_Agy99           ADHDFGTISVVGGAPLVLDYQIADDAVYSDGKQVTCDDLVLAWAAESGRY
MLBr_00489|M.leprae_Br4923          ADHDFGTITVVGGVPLVLDYQIADNAVYSDGKQVTCDDLVLTWAAQSGRF
MAV_3466|M.avium_104                PDRDFGTVSVVGGTPLVLDYQIADNAVYSDGKPVTCDDIVLAWAAQSGRY
MAB_2878c|M.abscessus_ATCC_199      ADHDFGTVEVVGRIPLVLDYTINEKAVYSDGKPVTCEDMVLSWFAQSGRM
                                     * ****: **   **:*** *  .******: :**:*:**:* ::*** 

Mflv_3814|M.gilvum_PYR-GCK          PAFDAASRSGYADIAAIECAPGQKKARVSFAPERAFTDYGQLFTATSMMP
Mvan_2585|M.vanbaalenii_PYR-1       PWFDAASRAGYADIATIDCAPGQKKARVSFAPDRGFTDYGQLFAATSMMP
MSMEG_2963|M.smegmatis_MC2_155      PGFDSASRAGYRDIGSVDCEPGQKRARVSFAQDRGFLDYGYLFAATSLMP
TH_0743|M.thermoresistible__bu      PGFDAASRAGYRDILTVDCAPGQKKARVSFAPDRGIVAYGQLFDATSLMP
Rv2585c|M.tuberculosis_H37Rv        PGFDAATQAGYVDIANIECTAGQKKARVSFIPDRSVVDHSQLFTATSLMP
Mb2616c|M.bovis_AF2122/97           PGFDAATQAGYVDIANIECTAGQKKARVSFIPDRSVVDHSQLFTATSLMP
MMAR_2122|M.marinum_M               AGFDAATQAGYVDIANIECTPGQKKARVSFIPDRAVVDYAQLFTATSLMP
MUL_1727|M.ulcerans_Agy99           AGFDAATQAGYVDIANIECTPGQKKARVSFIPDRAGVDYAQLFTATSLMP
MLBr_00489|M.leprae_Br4923          PGFDAATQAGYRDIANIECLAGQKKSRVFFVPDRSVVDYEQLFAATSMMP
MAV_3466|M.avium_104                PEFNAATQAGYLDIANVECMPGQKKARVSFIPDRGIVDYNQLFTATTLMP
MAB_2878c|M.abscessus_ATCC_199      PDFDTASTAGYADISTVDCKPGQKTARVTFAPDRAFTDWTQLFTATTMLP
                                    . *::*: :** **  ::* .*** :** *  :*.      ** **:::*

Mflv_3814|M.gilvum_PYR-GCK          SHVVGDVLGLGDGAVTTALLNNDIPAAERIAQVWNTTWNLGPDLD----L
Mvan_2585|M.vanbaalenii_PYR-1       SHVVADVLGLGEGGVTTALQTNDGPVVERIAQVWNTTWNLAPDLD----L
MSMEG_2963|M.smegmatis_MC2_155      SHVIADELGLGDGGVVTAFRDNDLNAIENIAKAWNTIWDLKPDID----L
TH_0743|M.thermoresistible__bu      AHVIADELGID---VIAAIRTQDAAAMERVAEVWNTIWDLSPDID----L
Rv2585c|M.tuberculosis_H37Rv        SHVIADQLHID---VTAALLSNNVSAVEQIARLWNSTWDLKPGRSHDEVR
Mb2616c|M.bovis_AF2122/97           SHVIADQLHID---VTAALLSNNVSAVEQIARLWNSTWDLKPGRSHDEVR
MMAR_2122|M.marinum_M               SHVLADELGID---VTAALLDNKAPQVEQIARLWNTTWDLKRG----VDL
MUL_1727|M.ulcerans_Agy99           SHVLADELGID---VTAALLDNKAPQVEQIARLWNTTWDLKRG----VDL
MLBr_00489|M.leprae_Br4923          SHVIADQLNID---VTEALLTHNATLVEQIARLWNTTWDLKPAVD----L
MAV_3466|M.avium_104                SHVIADQLNVD---VTAALLSHNAPLVAQIARLWNTIWDLKPGLKGEEIL
MAB_2878c|M.abscessus_ATCC_199      WHVVADKLGGN-IDLVGAIASNDVPALQKIADFWNNQWNLDTDLD----L
                                     **:.* *  .   :  *:  :.     .:*  **. *:*          

Mflv_3814|M.gilvum_PYR-GCK          KKFPSSGPYKLDSVTADGAVVLVANDKWWGAKPVTDRVTVWPRSPDIQDR
Mvan_2585|M.vanbaalenii_PYR-1       KKFPSSGPYKLDSVTEDGAVVLVANDKWWGTAPVTGRITVWPSSADMQDR
MSMEG_2963|M.smegmatis_MC2_155      KRFPSSGPYRLDSVSEDGSVVLVANDKWWGTPAITPKVTVWPRGADIQER
TH_0743|M.thermoresistible__bu      AKFPSSGPYKLDKVTEDGAVVLVANDKWWGAPPQTPTITVWPHSADTGDR
Rv2585c|M.tuberculosis_H37Rv        SRFPSSGPYKIESVLDDGAVVLVANDRWWGTKAITKRITVWPQGADIQDR
Mb2616c|M.bovis_AF2122/97           SRFPSSGPYKIESVLDDGAVVLVANDRWWGTKAITKRITVWPQGADIQDR
MMAR_2122|M.marinum_M               KHFPSSGPYKIESILDDGGVVLVANDRWWGAKAITKRVIVRPQGADIQDR
MUL_1727|M.ulcerans_Agy99           KHFPSSGPYKIESILDDGGVVLVANDRWWGAKAITKRVIVRPQGADIQDR
MLBr_00489|M.leprae_Br4923          RRFPSSGPYKIESVLNGGAVVLVANDRWWGLKATTKRITVRPQEADIQDR
MAV_3466|M.avium_104                KRFPSSGPYKLQAVLDGGAVVLVANDRWWGPKAITKRITVWPQGPDIQDR
MAB_2878c|M.abscessus_ATCC_199      SKFPSSGPYKLDGYNDDGSVVLVANDKWWGNPPVTKRVTVWPSGIDVQKR
                                     :*******:::    .*.*******:***  . *  : * *   *  .*

Mflv_3814|M.gilvum_PYR-GCK          VNEGAYDVVDIAAGSSGTLNVPDDYVRTDAPSAGIEQLIFAPEGALAAVP
Mvan_2585|M.vanbaalenii_PYR-1       VNEGAYDVVDIATGSSGTLNLPDDYVRTDSPSAGIEQLIFAPQGPLAAVP
MSMEG_2963|M.smegmatis_MC2_155      VNEGSFDVVDIATGSSGLLNLPDDYVSTDTPSAGIEQLIFAPRGPLGAPD
TH_0743|M.thermoresistible__bu      ISRGELDVVDIAAGSAGTLNLPDDYDASTSPSAGVQQMIFAPGGPLAAPP
Rv2585c|M.tuberculosis_H37Rv        VNNRSVDVVDVAAGSSGSLVTPDSYQRTDYPSAGIEQLIFAPQGSLAQSR
Mb2616c|M.bovis_AF2122/97           VNNRSVDVVDVAAGSSGSLVTPDSYQRTDYPSAGIEQLIFAPQGSLAQSR
MMAR_2122|M.marinum_M               VNNRDVDVVDVAAGSSGTLTTPDNYQRTDSPSEGIQQLIFSPKGPLADVR
MUL_1727|M.ulcerans_Agy99           VNNRDVDVVDVAAGSSGTLTTPDNYQRTDSPSEGIQQLIFSPKGPLADVR
MLBr_00489|M.leprae_Br4923          VNNRSVDVVDVAVGSSGSLATPDNYARIDSPSAGIEQLIFAPQGLLAAAA
MAV_3466|M.avium_104                VNNRSVDVVDVAAGSSGTLATPDNYDRSDAPSDGIEQLIFAPQGPLSAPK
MAB_2878c|M.abscessus_ATCC_199      LSDGDLEVVDVAAGSAGTLTAPDGFVRTEEPGSGVEQLIFGAGGSVGAPD
                                    :.    :***:*.**:* *  **.:     *. *::*:**.. * :.   

Mflv_3814|M.gilvum_PYR-GCK          ARRALAFCTPRDVIARNAEVPVVNARLTTATEDAIGSAELTPQINEFAVA
Mvan_2585|M.vanbaalenii_PYR-1       ARRALALCTPRDVIARSAELPVANARLNAATEDAYGAAESTPQVNEFAVA
MSMEG_2963|M.smegmatis_MC2_155      ARRAVALCTPRDVIARNAEMPIANARLSPASEDAFSVAEGTAEGGRFSVA
TH_0743|M.thermoresistible__bu      ARRALALCTPRDVLARNAGVPIVNARLNAAEEDAFGVAEAGAEGGQFTAA
Rv2585c|M.tuberculosis_H37Rv        TRRALALCVPRDAIARDAGVPIANSRLSPATDDALTDADGAAEARQFGRV
Mb2616c|M.bovis_AF2122/97           TRRALALCVPRDAIARDAGVPIANSRLSPATDDALTDADGAAEARQFGRV
MMAR_2122|M.marinum_M               NRRAVALCTPRDAISRDAGVPIANSRLNPATEDAIAGADGTAEGGKFTKG
MUL_1727|M.ulcerans_Agy99           NRRAVALCTPRDAISRDAGVPIANSRLNPATEDAIAGADGTAEGGKFTKG
MLBr_00489|M.leprae_Br4923          ARRALALCTPRDVVARDAGLSIANSRLSPATEDAIAAADGAREAGQFSKA
MAV_3466|M.avium_104                ARRAFALCTPRDVLAKDAGTPIANSRLDPAVDDAVSAGDGAAEAAPFGKA
MAB_2878c|M.abscessus_ATCC_199      LRRAVALCTPRDAIAGIAGVPVMNARLDTSIGDSFASVEAAAEAGRFMRS
                                     ***.*:*.***.::  *  .: *:** .:  *:    :   :   *   

Mflv_3814|M.gilvum_PYR-GCK          NPDAARQALGNTPLTVRIGYQTPNARLAATVGTIAKACAPAGITVQDAAN
Mvan_2585|M.vanbaalenii_PYR-1       NPDAARAALNGAPLTVRIGYQTPNARLAATVGTIAKACAPAGITVEDAAA
MSMEG_2963|M.smegmatis_MC2_155      NPDAARDALDNRPLTVRIGYQTPNARLAAIVGAIAKACAPAGITVQDAGS
TH_0743|M.thermoresistible__bu      DPEAAREALGGEPLRVRIGYQSPNPRMAAAVGVIAEACTPAGITVEDAAT
Rv2585c|M.tuberculosis_H37Rv        DPAAARDALGGTPLTVRIGYGRPNARLAATIGTIADACAPAGITVSDVTV
Mb2616c|M.bovis_AF2122/97           DPAAARDALGGTPLTVRIGYGRPNARLAATIGTIADACAPAGITVSDVTV
MMAR_2122|M.marinum_M               DPGAARDALGGAPLTLRIGYHGPNARLAAIIGAIAKSCGPAGISVSDVTL
MUL_1727|M.ulcerans_Agy99           DPGAARDALGGAPLTLRIGYHGPNARLAAIIGAIAKSCGPAGISVSDVTL
MLBr_00489|M.leprae_Br4923          DPAAAHDALSGETLPVRIGYQGPNARLAATVGTIAKACAVAGISVSSVTL
MAV_3466|M.avium_104                DPVAAREALGGAPLAVRIGYQGPNARLAVNVGVITKACAPAGITVSGVTL
MAB_2878c|M.abscessus_ATCC_199      DPIAARAAAANRPLTLRVGYQAPNPRRAAIVSAMAQACEPAGITVQDVSS
                                    :* **: *  . .* :*:**  **.* *. :..::.:*  ***:*...  

Mflv_3814|M.gilvum_PYR-GCK          AD----TGPTALRDNQIDVLIASTGGAAGSGSSGSSAVDAYTLHSGNGNN
Mvan_2585|M.vanbaalenii_PYR-1       EG----IGPLSLRDNEIDVLIAGTGGAAGSGSSGSSAMDAYTLHSGNGNN
MSMEG_2963|M.smegmatis_MC2_155      ET----AGPIALRNNEIDALLASTGGAAGAGSSGSSAIDAYTLHVGNGNN
TH_0743|M.thermoresistible__bu      ET----TGPLTLRDNEIDVLLAGTGGAAGSGSTGASTMDAYTLHSGNGNN
Rv2585c|M.tuberculosis_H37Rv        DT----PGPQALRDGKIDVLLASTGGATGSGSSGSCAMDAYDLHSGNGNN
Mb2616c|M.bovis_AF2122/97           DT----PGPQALRDGKIDVLLASTGGATGSGSSGSSAMDAYDLHSGNGNN
MMAR_2122|M.marinum_M               DT----AGPGALRDGKIDVLLASTGGASGSGSTGSSSMDAYDLHSGNGNN
MUL_1727|M.ulcerans_Agy99           DT----AGPGALRDGKIDVLLASTGGASGSGSTGSSSMDAYDLHSGNGNN
MLBr_00489|M.leprae_Br4923          DSSTDPSGPQALRDGKIDVLLASTGGATGSGSSGSSSMDAYDLHTGNGNN
MAV_3466|M.avium_104                DS----AGPQALRDGKIDALLASTGGATGSGSSGSSAMDAYALHTGNGNN
MAB_2878c|M.abscessus_ATCC_199      PE----TGPHSLRDNQVDALLSSIGGVPGSGSTGSWLMDAYALRSREGKN
                                           ** :**:.::*.*::. **..*:**:*:  :*** *:  :*:*

Mflv_3814|M.gilvum_PYR-GCK          LPRYANGRIDAIISTLAVTTDPKEFARLLGEAGPILWADMPTLPLYRQQR
Mvan_2585|M.vanbaalenii_PYR-1       LPRYRNERIDAIIATMAVTSDPKELARLLGEAGPILWGDMPTLPLYRQQR
MSMEG_2963|M.smegmatis_MC2_155      LPNYNNERIDGIIDALAVTSDPKELARLLGEGAPILWNDVPTLPLYRQQR
TH_0743|M.thermoresistible__bu      LSGYRNERVDGIIDALAVTSDPKEVARLLAEGAPMLWGDLPTLPLYRQQR
Rv2585c|M.tuberculosis_H37Rv        LSGYANAQIDGIISALAVSADPAERARLLAEAAPVLWDEMPTLPLYRQQR
Mb2616c|M.bovis_AF2122/97           LSGYANAQIDGIISALAVSADPAERARLLAEAAPVLWDEMPTLPLYRQQR
MMAR_2122|M.marinum_M               LSGYANPQIDGIISALAVSADPAERVRLLAEGAPVLWDEMPTLPLYRQER
MUL_1727|M.ulcerans_Agy99           LSGYANPQIDGIISGLAVSADPAERVRLLAEGAPVLWDEMPTLPLYRQER
MLBr_00489|M.leprae_Br4923          LSGYANAQVDNNIGALAVSADPAERVRLLADSAPVLWADMPTLPLYRQQR
MAV_3466|M.avium_104                LSGYSNPQVDNAIGALAVSADPAERVRLLAETAPVLWGDLPTLPLYRQQR
MAB_2878c|M.abscessus_ATCC_199      PANYANGQIDGIIAALAVTTNARDQSRLLGDASAILWNDLPTLPLYRQPR
                                     . * * ::*  *  :**:::. :  ***.: ..:** ::******** *

Mflv_3814|M.gilvum_PYR-GCK          TLLTSTKMSAVIGNPTRWGAGWNMDRWKLSR
Mvan_2585|M.vanbaalenii_PYR-1       TLLTSTKMYAVSGNPTRWGAGWNMDRWKLSQ
MSMEG_2963|M.smegmatis_MC2_155      TVLTSNKMYAVSGNPTRWGAGWNMDRWKLSK
TH_0743|M.thermoresistible__bu      TIVTSNDMYAVSGNPTRWGAGWNMDRWVLRR
Rv2585c|M.tuberculosis_H37Rv        TLLMSTKMYAVSRNPTRWGAGWNMDRWALAR
Mb2616c|M.bovis_AF2122/97           TLLMSTKMYAVSRNPTRWGAGWNMDRWALAR
MMAR_2122|M.marinum_M               TLLMSKKMYAVSRNPTRWGAGWNMDRWALMQ
MUL_1727|M.ulcerans_Agy99           TLLMSKKMYAVSRNPTRWGAGWNMDRWALMQ
MLBr_00489|M.leprae_Br4923          MLLMSKTMYAVTRNPTRWGAGWNMDRWALVR
MAV_3466|M.avium_104                TLLISKKMYAVSKNPTRWGAGWNMDRWALVQ
MAB_2878c|M.abscessus_ATCC_199      VLIAPKSMYAATPSVTRWGAGWNMDRWVLPT
                                     :: .. * *.  . ************ *