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VRRRATALTAVLALIGGLGLSSCADDTADAVDYAVDGTLVTYNTNTVVGAASAGPQAFARVLTGFNYHGP DGQIVGDHDFGTISVVGRSPLILDYEIKAEAVYSDGKPITCDDMVLAWASQSGRYPWFDAASRAGYADIA TIDCAPGQKKARVSFAPDRGFTDYGQLFAATSMMPSHVVADVLGLGEGGVTTALQTNDGPVVERIAQVWN TTWNLAPDLDLKKFPSSGPYKLDSVTEDGAVVLVANDKWWGTAPVTGRITVWPSSADMQDRVNEGAYDVV DIATGSSGTLNLPDDYVRTDSPSAGIEQLIFAPQGPLAAVPARRALALCTPRDVIARSAELPVANARLNA ATEDAYGAAESTPQVNEFAVANPDAARAALNGAPLTVRIGYQTPNARLAATVGTIAKACAPAGITVEDAA AEGIGPLSLRDNEIDVLIAGTGGAAGSGSSGSSAMDAYTLHSGNGNNLPRYRNERIDAIIATMAVTSDPK ELARLLGEAGPILWGDMPTLPLYRQQRTLLTSTKMYAVSGNPTRWGAGWNMDRWKLSQ
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2585 | - | - | 100% (548) | extracellular solute-binding protein |
| M. vanbaalenii PYR-1 | Mvan_4433 | - | 2e-16 | 23.80% (479) | extracellular solute-binding protein |
| M. vanbaalenii PYR-1 | Mvan_4539 | - | 8e-14 | 23.55% (467) | extracellular solute-binding protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2616c | - | 0.0 | 65.11% (556) | lipoprotein |
| M. gilvum PYR-GCK | Mflv_3814 | - | 0.0 | 85.32% (545) | extracellular solute-binding protein |
| M. tuberculosis H37Rv | Rv2585c | - | 0.0 | 64.93% (556) | lipoprotein |
| M. leprae Br4923 | MLBr_00489 | - | 0.0 | 64.72% (547) | putative lipoprotein |
| M. abscessus ATCC 19977 | MAB_2878c | - | 0.0 | 58.20% (543) | hypothetical protein MAB_2878c |
| M. marinum M | MMAR_2122 | - | 0.0 | 65.50% (542) | ABC-type dipeptide transport system, periplasmic component |
| M. avium 104 | MAV_3466 | - | 0.0 | 64.56% (539) | extracellular solute-binding protein, family protein 5 |
| M. smegmatis MC2 155 | MSMEG_2963 | - | 0.0 | 74.95% (547) | extracellular solute-binding protein, family protein 5 |
| M. thermoresistible (build 8) | TH_0743 | - | 0.0 | 73.28% (539) | POSSIBLE CONSERVED LIPOPROTEIN |
| M. ulcerans Agy99 | MUL_1727 | - | 0.0 | 65.50% (542) | ABC-type dipeptide transport system, periplasmic component |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_2585|M.vanbaalenii_PYR-1 --------MRRRATALT-----------------AVLALIGGLGLSSCAD
Mflv_3814|M.gilvum_PYR-GCK --------MAGRWRALT-----------------AVLAVVGGLGLTSCGE
MSMEG_2963|M.smegmatis_MC2_155 -MAHRSATARARAAVVL-----------------AVLSLLAGVGLTSCGS
TH_0743|M.thermoresistible__bu --------------VLI-----------------AVLLAVGG-GVSACGG
MMAR_2122|M.marinum_M MASCRRERNFSRWSGLRNVLRRGFGGNGHKIAAVGVAALAAASSLSACSG
MUL_1727|M.ulcerans_Agy99 MASCRRERNFSRWSGLRNVLRRGFGGNGHKIAAVGVAALAAASSLSACSG
Mb2616c|M.bovis_AF2122/97 MAPRRR--RHTRIAGLR---------------VVGTATLVAATTLTACSG
Rv2585c|M.tuberculosis_H37Rv MAPRRR--RHTRIAGLR---------------VVGTATLVAATTLTACSG
MLBr_00489|M.leprae_Br4923 --MRSGLFGVLRWTAVG-----------------LVATLVASLALTACSG
MAV_3466|M.avium_104 MAIRIGRRGLTGWVGIG-----------------VAVLVVAGVTLAGCAG
MAB_2878c|M.abscessus_ATCC_199 MDSRSPARTGARRIARIG--------------AIVTTVLLAAGLLTSCWT
. .. ::.*
Mvan_2585|M.vanbaalenii_PYR-1 DTADAVDYAVDGTLVTYNTNTVVGAASAGPQAFARVLTGFNYHGPDGQIV
Mflv_3814|M.gilvum_PYR-GCK ATADSVDYAVDGVLTSYNTNTVVGAASAGPQAFARVLTGFSYHGPEGQIV
MSMEG_2963|M.smegmatis_MC2_155 GSAGEIDYAVDGTLTTYNTNTVAGAASSGPQAFARTLTGFAYHGPDGQVV
TH_0743|M.thermoresistible__bu GTADEIDYAIDGRLTTYNTNTVAGAASGGPQAFARVLTGFHYRGPDGQII
MMAR_2122|M.marinum_M SAAGQIDYVVDGPLPTYNTNTVTGAASAGAQAFARVLTGFGYHGPDGQVV
MUL_1727|M.ulcerans_Agy99 SAAGQIDYVVDGPLPTYNTNTVTGAASAGAQAFARVLTGFGYHGPDGQVV
Mb2616c|M.bovis_AF2122/97 SAAAQIDYVVDGALVTYNTNTVIGAASAGAQAFARTLTGFGYHGPDGQVV
Rv2585c|M.tuberculosis_H37Rv SAAAQIDYVVDGALVTYNTNTVIGAASAGAQAFARTLTGFGYHGPDGQVV
MLBr_00489|M.leprae_Br4923 SAAGEIVYVVDGALGTYNTNTIVGAASAGAQAFARTLIGFGYHGPDGQIV
MAV_3466|M.avium_104 SAAAEIDYVVDGPLSSYNPNTVVGAASAGAQAFARTLVGFSYHGPDGQTV
MAB_2878c|M.abscessus_ATCC_199 SAAKTLDYAVDGRLTTYNVNSVAGNASAGAQAFNRVLTGFGFHGPDGQVI
:* : *.:** * :** *:: * **.*.*** *.* ** ::**:** :
Mvan_2585|M.vanbaalenii_PYR-1 GDHDFGTISVVGRSPLILDYEIKAEAVYSDGKPITCDDMVLAWASQSGRY
Mflv_3814|M.gilvum_PYR-GCK GDHDFGTISVVGRTPLILDYEIKPEAVYSDGKPITCDDMVLAWASQSGRF
MSMEG_2963|M.smegmatis_MC2_155 ADHDFGTMSVVGRAPLVLDYVINDNAVYSDGKPITCDDMVLTWAAQSGRF
TH_0743|M.thermoresistible__bu GDTDFGTVSVVGRSPLVLDYEINPDAVYSDGKPVTCDDMVLAWAAQSGRF
MMAR_2122|M.marinum_M ADHDFGTISVVGGAPLVLDYQIADDAVYSDGKQVTCDDLVLAWAAESGRY
MUL_1727|M.ulcerans_Agy99 ADHDFGTISVVGGAPLVLDYQIADDAVYSDGKQVTCDDLVLAWAAESGRY
Mb2616c|M.bovis_AF2122/97 ADRDFGTVSVVEGSPLILDYQISDDAVYSDGRPVTCDDLVLAWAAQSGRF
Rv2585c|M.tuberculosis_H37Rv ADRDFGTVSVVEGSPLILDYQISDDAVYSDGRPVTCDDLVLAWAAQSGRF
MLBr_00489|M.leprae_Br4923 ADHDFGTITVVGGVPLVLDYQIADNAVYSDGKQVTCDDLVLTWAAQSGRF
MAV_3466|M.avium_104 PDRDFGTVSVVGGTPLVLDYQIADNAVYSDGKPVTCDDIVLAWAAQSGRY
MAB_2878c|M.abscessus_ATCC_199 ADHDFGTVEVVGRIPLVLDYTINEKAVYSDGKPVTCEDMVLSWFAQSGRM
* ****: ** **:*** * .******: :**:*:**:* ::***
Mvan_2585|M.vanbaalenii_PYR-1 PWFDAASRAGYADIATIDCAPGQKKARVSFAPDRGFTDYGQLFAATSMMP
Mflv_3814|M.gilvum_PYR-GCK PAFDAASRSGYADIAAIECAPGQKKARVSFAPERAFTDYGQLFTATSMMP
MSMEG_2963|M.smegmatis_MC2_155 PGFDSASRAGYRDIGSVDCEPGQKRARVSFAQDRGFLDYGYLFAATSLMP
TH_0743|M.thermoresistible__bu PGFDAASRAGYRDILTVDCAPGQKKARVSFAPDRGIVAYGQLFDATSLMP
MMAR_2122|M.marinum_M AGFDAATQAGYVDIANIECTPGQKKARVSFIPDRAVVDYAQLFTATSLMP
MUL_1727|M.ulcerans_Agy99 AGFDAATQAGYVDIANIECTPGQKKARVSFIPDRAGVDYAQLFTATSLMP
Mb2616c|M.bovis_AF2122/97 PGFDAATQAGYVDIANIECTAGQKKARVSFIPDRSVVDHSQLFTATSLMP
Rv2585c|M.tuberculosis_H37Rv PGFDAATQAGYVDIANIECTAGQKKARVSFIPDRSVVDHSQLFTATSLMP
MLBr_00489|M.leprae_Br4923 PGFDAATQAGYRDIANIECLAGQKKSRVFFVPDRSVVDYEQLFAATSMMP
MAV_3466|M.avium_104 PEFNAATQAGYLDIANVECMPGQKKARVSFIPDRGIVDYNQLFTATTLMP
MAB_2878c|M.abscessus_ATCC_199 PDFDTASTAGYADISTVDCKPGQKTARVTFAPDRAFTDWTQLFTATTMLP
. *::*: :** ** ::* .*** :** * :*. ** **:::*
Mvan_2585|M.vanbaalenii_PYR-1 SHVVADVLGLGEGGVTTALQTNDGPVVERIAQVWNTTWNLAPDLD----L
Mflv_3814|M.gilvum_PYR-GCK SHVVGDVLGLGDGAVTTALLNNDIPAAERIAQVWNTTWNLGPDLD----L
MSMEG_2963|M.smegmatis_MC2_155 SHVIADELGLGDGGVVTAFRDNDLNAIENIAKAWNTIWDLKPDID----L
TH_0743|M.thermoresistible__bu AHVIADELGID---VIAAIRTQDAAAMERVAEVWNTIWDLSPDID----L
MMAR_2122|M.marinum_M SHVLADELGID---VTAALLDNKAPQVEQIARLWNTTWDLKRG----VDL
MUL_1727|M.ulcerans_Agy99 SHVLADELGID---VTAALLDNKAPQVEQIARLWNTTWDLKRG----VDL
Mb2616c|M.bovis_AF2122/97 SHVIADQLHID---VTAALLSNNVSAVEQIARLWNSTWDLKPGRSHDEVR
Rv2585c|M.tuberculosis_H37Rv SHVIADQLHID---VTAALLSNNVSAVEQIARLWNSTWDLKPGRSHDEVR
MLBr_00489|M.leprae_Br4923 SHVIADQLNID---VTEALLTHNATLVEQIARLWNTTWDLKPAVD----L
MAV_3466|M.avium_104 SHVIADQLNVD---VTAALLSHNAPLVAQIARLWNTIWDLKPGLKGEEIL
MAB_2878c|M.abscessus_ATCC_199 WHVVADKLGGN-IDLVGAIASNDVPALQKIADFWNNQWNLDTDLD----L
**:.* * . : *: :. .:* **. *:*
Mvan_2585|M.vanbaalenii_PYR-1 KKFPSSGPYKLDSVTEDGAVVLVANDKWWGTAPVTGRITVWPSSADMQDR
Mflv_3814|M.gilvum_PYR-GCK KKFPSSGPYKLDSVTADGAVVLVANDKWWGAKPVTDRVTVWPRSPDIQDR
MSMEG_2963|M.smegmatis_MC2_155 KRFPSSGPYRLDSVSEDGSVVLVANDKWWGTPAITPKVTVWPRGADIQER
TH_0743|M.thermoresistible__bu AKFPSSGPYKLDKVTEDGAVVLVANDKWWGAPPQTPTITVWPHSADTGDR
MMAR_2122|M.marinum_M KHFPSSGPYKIESILDDGGVVLVANDRWWGAKAITKRVIVRPQGADIQDR
MUL_1727|M.ulcerans_Agy99 KHFPSSGPYKIESILDDGGVVLVANDRWWGAKAITKRVIVRPQGADIQDR
Mb2616c|M.bovis_AF2122/97 SRFPSSGPYKIESVLDDGAVVLVANDRWWGTKAITKRITVWPQGADIQDR
Rv2585c|M.tuberculosis_H37Rv SRFPSSGPYKIESVLDDGAVVLVANDRWWGTKAITKRITVWPQGADIQDR
MLBr_00489|M.leprae_Br4923 RRFPSSGPYKIESVLNGGAVVLVANDRWWGLKATTKRITVRPQEADIQDR
MAV_3466|M.avium_104 KRFPSSGPYKLQAVLDGGAVVLVANDRWWGPKAITKRITVWPQGPDIQDR
MAB_2878c|M.abscessus_ATCC_199 SKFPSSGPYKLDGYNDDGSVVLVANDKWWGNPPVTKRVTVWPSGIDVQKR
:*******::: .*.*******:*** . * : * * * .*
Mvan_2585|M.vanbaalenii_PYR-1 VNEGAYDVVDIATGSSGTLNLPDDYVRTDSPSAGIEQLIFAPQGPLAAVP
Mflv_3814|M.gilvum_PYR-GCK VNEGAYDVVDIAAGSSGTLNVPDDYVRTDAPSAGIEQLIFAPEGALAAVP
MSMEG_2963|M.smegmatis_MC2_155 VNEGSFDVVDIATGSSGLLNLPDDYVSTDTPSAGIEQLIFAPRGPLGAPD
TH_0743|M.thermoresistible__bu ISRGELDVVDIAAGSAGTLNLPDDYDASTSPSAGVQQMIFAPGGPLAAPP
MMAR_2122|M.marinum_M VNNRDVDVVDVAAGSSGTLTTPDNYQRTDSPSEGIQQLIFSPKGPLADVR
MUL_1727|M.ulcerans_Agy99 VNNRDVDVVDVAAGSSGTLTTPDNYQRTDSPSEGIQQLIFSPKGPLADVR
Mb2616c|M.bovis_AF2122/97 VNNRSVDVVDVAAGSSGSLVTPDSYQRTDYPSAGIEQLIFAPQGSLAQSR
Rv2585c|M.tuberculosis_H37Rv VNNRSVDVVDVAAGSSGSLVTPDSYQRTDYPSAGIEQLIFAPQGSLAQSR
MLBr_00489|M.leprae_Br4923 VNNRSVDVVDVAVGSSGSLATPDNYARIDSPSAGIEQLIFAPQGLLAAAA
MAV_3466|M.avium_104 VNNRSVDVVDVAAGSSGTLATPDNYDRSDAPSDGIEQLIFAPQGPLSAPK
MAB_2878c|M.abscessus_ATCC_199 LSDGDLEVVDVAAGSAGTLTAPDGFVRTEEPGSGVEQLIFGAGGSVGAPD
:. :***:*.**:* * **.: *. *::*:**.. * :.
Mvan_2585|M.vanbaalenii_PYR-1 ARRALALCTPRDVIARSAELPVANARLNAATEDAYGAAESTPQVNEFAVA
Mflv_3814|M.gilvum_PYR-GCK ARRALAFCTPRDVIARNAEVPVVNARLTTATEDAIGSAELTPQINEFAVA
MSMEG_2963|M.smegmatis_MC2_155 ARRAVALCTPRDVIARNAEMPIANARLSPASEDAFSVAEGTAEGGRFSVA
TH_0743|M.thermoresistible__bu ARRALALCTPRDVLARNAGVPIVNARLNAAEEDAFGVAEAGAEGGQFTAA
MMAR_2122|M.marinum_M NRRAVALCTPRDAISRDAGVPIANSRLNPATEDAIAGADGTAEGGKFTKG
MUL_1727|M.ulcerans_Agy99 NRRAVALCTPRDAISRDAGVPIANSRLNPATEDAIAGADGTAEGGKFTKG
Mb2616c|M.bovis_AF2122/97 TRRALALCVPRDAIARDAGVPIANSRLSPATDDALTDADGAAEARQFGRV
Rv2585c|M.tuberculosis_H37Rv TRRALALCVPRDAIARDAGVPIANSRLSPATDDALTDADGAAEARQFGRV
MLBr_00489|M.leprae_Br4923 ARRALALCTPRDVVARDAGLSIANSRLSPATEDAIAAADGAREAGQFSKA
MAV_3466|M.avium_104 ARRAFALCTPRDVLAKDAGTPIANSRLDPAVDDAVSAGDGAAEAAPFGKA
MAB_2878c|M.abscessus_ATCC_199 LRRAVALCTPRDAIAGIAGVPVMNARLDTSIGDSFASVEAAAEAGRFMRS
***.*:*.***.:: * .: *:** .: *: : : *
Mvan_2585|M.vanbaalenii_PYR-1 NPDAARAALNGAPLTVRIGYQTPNARLAATVGTIAKACAPAGITVEDAAA
Mflv_3814|M.gilvum_PYR-GCK NPDAARQALGNTPLTVRIGYQTPNARLAATVGTIAKACAPAGITVQDAAN
MSMEG_2963|M.smegmatis_MC2_155 NPDAARDALDNRPLTVRIGYQTPNARLAAIVGAIAKACAPAGITVQDAGS
TH_0743|M.thermoresistible__bu DPEAAREALGGEPLRVRIGYQSPNPRMAAAVGVIAEACTPAGITVEDAAT
MMAR_2122|M.marinum_M DPGAARDALGGAPLTLRIGYHGPNARLAAIIGAIAKSCGPAGISVSDVTL
MUL_1727|M.ulcerans_Agy99 DPGAARDALGGAPLTLRIGYHGPNARLAAIIGAIAKSCGPAGISVSDVTL
Mb2616c|M.bovis_AF2122/97 DPAAARDALGGTPLTVRIGYGRPNARLAATIGTIADACAPAGITVSDVTV
Rv2585c|M.tuberculosis_H37Rv DPAAARDALGGTPLTVRIGYGRPNARLAATIGTIADACAPAGITVSDVTV
MLBr_00489|M.leprae_Br4923 DPAAAHDALSGETLPVRIGYQGPNARLAATVGTIAKACAVAGISVSSVTL
MAV_3466|M.avium_104 DPVAAREALGGAPLAVRIGYQGPNARLAVNVGVITKACAPAGITVSGVTL
MAB_2878c|M.abscessus_ATCC_199 DPIAARAAAANRPLTLRVGYQAPNPRRAAIVSAMAQACEPAGITVQDVSS
:* **: * . .* :*:** **.* *. :..::.:* ***:*...
Mvan_2585|M.vanbaalenii_PYR-1 EG----IGPLSLRDNEIDVLIAGTGGAAGSGSSGSSAMDAYTLHSGNGNN
Mflv_3814|M.gilvum_PYR-GCK AD----TGPTALRDNQIDVLIASTGGAAGSGSSGSSAVDAYTLHSGNGNN
MSMEG_2963|M.smegmatis_MC2_155 ET----AGPIALRNNEIDALLASTGGAAGAGSSGSSAIDAYTLHVGNGNN
TH_0743|M.thermoresistible__bu ET----TGPLTLRDNEIDVLLAGTGGAAGSGSTGASTMDAYTLHSGNGNN
MMAR_2122|M.marinum_M DT----AGPGALRDGKIDVLLASTGGASGSGSTGSSSMDAYDLHSGNGNN
MUL_1727|M.ulcerans_Agy99 DT----AGPGALRDGKIDVLLASTGGASGSGSTGSSSMDAYDLHSGNGNN
Mb2616c|M.bovis_AF2122/97 DT----PGPQALRDGKIDVLLASTGGATGSGSSGSSAMDAYDLHSGNGNN
Rv2585c|M.tuberculosis_H37Rv DT----PGPQALRDGKIDVLLASTGGATGSGSSGSCAMDAYDLHSGNGNN
MLBr_00489|M.leprae_Br4923 DSSTDPSGPQALRDGKIDVLLASTGGATGSGSSGSSSMDAYDLHTGNGNN
MAV_3466|M.avium_104 DS----AGPQALRDGKIDALLASTGGATGSGSSGSSAMDAYALHTGNGNN
MAB_2878c|M.abscessus_ATCC_199 PE----TGPHSLRDNQVDALLSSIGGVPGSGSTGSWLMDAYALRSREGKN
** :**:.::*.*::. **..*:**:*: :*** *: :*:*
Mvan_2585|M.vanbaalenii_PYR-1 LPRYRNERIDAIIATMAVTSDPKELARLLGEAGPILWGDMPTLPLYRQQR
Mflv_3814|M.gilvum_PYR-GCK LPRYANGRIDAIISTLAVTTDPKEFARLLGEAGPILWADMPTLPLYRQQR
MSMEG_2963|M.smegmatis_MC2_155 LPNYNNERIDGIIDALAVTSDPKELARLLGEGAPILWNDVPTLPLYRQQR
TH_0743|M.thermoresistible__bu LSGYRNERVDGIIDALAVTSDPKEVARLLAEGAPMLWGDLPTLPLYRQQR
MMAR_2122|M.marinum_M LSGYANPQIDGIISALAVSADPAERVRLLAEGAPVLWDEMPTLPLYRQER
MUL_1727|M.ulcerans_Agy99 LSGYANPQIDGIISGLAVSADPAERVRLLAEGAPVLWDEMPTLPLYRQER
Mb2616c|M.bovis_AF2122/97 LSGYANAQIDGIISALAVSADPAERARLLAEAAPVLWDEMPTLPLYRQQR
Rv2585c|M.tuberculosis_H37Rv LSGYANAQIDGIISALAVSADPAERARLLAEAAPVLWDEMPTLPLYRQQR
MLBr_00489|M.leprae_Br4923 LSGYANAQVDNNIGALAVSADPAERVRLLADSAPVLWADMPTLPLYRQQR
MAV_3466|M.avium_104 LSGYSNPQVDNAIGALAVSADPAERVRLLAETAPVLWGDLPTLPLYRQQR
MAB_2878c|M.abscessus_ATCC_199 PANYANGQIDGIIAALAVTTNARDQSRLLGDASAILWNDLPTLPLYRQPR
. * * ::* * :**:::. : ***.: ..:** ::******** *
Mvan_2585|M.vanbaalenii_PYR-1 TLLTSTKMYAVSGNPTRWGAGWNMDRWKLSQ
Mflv_3814|M.gilvum_PYR-GCK TLLTSTKMSAVIGNPTRWGAGWNMDRWKLSR
MSMEG_2963|M.smegmatis_MC2_155 TVLTSNKMYAVSGNPTRWGAGWNMDRWKLSK
TH_0743|M.thermoresistible__bu TIVTSNDMYAVSGNPTRWGAGWNMDRWVLRR
MMAR_2122|M.marinum_M TLLMSKKMYAVSRNPTRWGAGWNMDRWALMQ
MUL_1727|M.ulcerans_Agy99 TLLMSKKMYAVSRNPTRWGAGWNMDRWALMQ
Mb2616c|M.bovis_AF2122/97 TLLMSTKMYAVSRNPTRWGAGWNMDRWALAR
Rv2585c|M.tuberculosis_H37Rv TLLMSTKMYAVSRNPTRWGAGWNMDRWALAR
MLBr_00489|M.leprae_Br4923 MLLMSKTMYAVTRNPTRWGAGWNMDRWALVR
MAV_3466|M.avium_104 TLLISKKMYAVSKNPTRWGAGWNMDRWALVQ
MAB_2878c|M.abscessus_ATCC_199 VLIAPKSMYAATPSVTRWGAGWNMDRWVLPT
:: .. * *. . ************ *