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AEDQLTAQAVAPPTEASAALEPALETPESPVETLKTSISASRRVRARLARRMTAQRSTTNPVLEPLVAVH REIYPKADLSILQRAYEVADQRHASQLRQSGDPYITHPLAVANILAELGMDTTTLVAALLHDTVEDTGYT LEALTEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRKMITAMARDPRVLVIKVADRLHNMRTMRFLPPE KQARKARETLEVIAPLAHRLGMASVKWELEDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNT LTASKIKATVEGRPKHYWSIYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKD YIAQPRYGVYQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLHPHAAAEIDDMA WMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHTEVGHRCIGARVN GRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPRAKTKIRQWFAKERREEALETGKDAMAREVR RGGLPLQRLVNGESMAAVARELHYADVSALYTAIGEGHVSAKHVVQRLLAELGGIDQAEEELAERSTPAT MPRRPRSTDDVGVSVPGAPGVLTKLAKCCTPVPGDVIMGFVTRGGGVSVHRTDCTNAASLQQQAERIIEV LWAPSPSSVFLVAIQVEALDRHRLLSDVTRALADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLL NAVRNVEGVYDVYRVTSAA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2583c | relA | - | 100% (790) | PROBABLE GTP PYROPHOSPHOKINASE RELA (ATP:GTP 3'-PYROPHOSPHOTRANSFERASE) (PPGPP SYNTHETASE I) ((P)PPGPP SYNTHETASE) (GTP DIPHOSPHOKINASE) |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2614c | relA | 0.0 | 100.00% (790) | GTP pyrophosphokinase |
| M. gilvum PYR-GCK | Mflv_3812 | - | 0.0 | 88.01% (792) | (p)ppGpp synthetase I, SpoT/RelA |
| M. leprae Br4923 | MLBr_00491 | relA | 0.0 | 93.54% (790) | putative GTP pyrophosphokinase |
| M. abscessus ATCC 19977 | MAB_2876c | - | 0.0 | 88.62% (782) | GTP pyrophosphokinase |
| M. marinum M | MMAR_2124 | relA | 0.0 | 92.79% (791) | GTP pyrophosphokinase RelA |
| M. avium 104 | MAV_3464 | relA | 0.0 | 93.16% (790) | GTP pyrophosphokinase |
| M. smegmatis MC2 155 | MSMEG_2965 | relA | 0.0 | 89.97% (778) | GTP pyrophosphokinase |
| M. thermoresistible (build 8) | TH_0745 | relA | 0.0 | 86.96% (790) | PROBABLE GTP PYROPHOSPHOKINASE RELA (ATP:GTP |
| M. ulcerans Agy99 | MUL_1729 | relA | 0.0 | 92.41% (791) | GTP pyrophosphokinase RelA |
| M. vanbaalenii PYR-1 | Mvan_2587 | - | 0.0 | 88.37% (791) | (p)ppGpp synthetase I, SpoT/RelA |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3812|M.gilvum_PYR-GCK ---MADKVRTDPGSGQAVQTPP--------PAASASPET---QPMEIVKP
Mvan_2587|M.vanbaalenii_PYR-1 ---MADKVRTEPVAGQAVQSPP--------PPV-ATPET---QPMELPKP
MSMEG_2965|M.smegmatis_MC2_155 ---MVD----EPGKGQAVQSPPAVPETVPKPPSGTAPTTTPAAPSTSSET
TH_0745|M.thermoresistible__bu -VMMAD----DPRSTQAVQPPQ--------------------EPVEPPKP
MAB_2876c|M.abscessus_ATCC_199 ---MAD-EHVPSENQVAVESLP------------ALSEPGPVTESLRVSG
Rv2583c|M.tuberculosis_H37Rv ---MAE----DQLTAQAVAPPTE-----ASAALEPALETPES-PVETLKT
Mb2614c|M.bovis_AF2122/97 ---MAE----DQLTAQAVAPPTE-----ASAALEPALETPES-PVETLKT
MLBr_00491|M.leprae_Br4923 ---MAD----DQGTAQALQP--------VQVVPGPAVEAPET-PVETLKT
MAV_3464|M.avium_104 MSIVAE----ENSAAQALDAP-------AESPPNPVIETPEP-PTESLKT
MMAR_2124|M.marinum_M ---MAD----DQSTTQAVVP---------SVESPPVVEAPEAAPAETLKT
MUL_1729|M.ulcerans_Agy99 MTTVAD----DQSTTQAVVP---------SVESPPVVEAPEAAPAETLKT
:.: *: . .
Mflv_3812|M.gilvum_PYR-GCK APTSASRRVRARLARRMTSQRSTVNPVLEPLVAVHREIYPKADLTLLQKA
Mvan_2587|M.vanbaalenii_PYR-1 -PTSASRRVRARLARRMTSQRSTINPVLEPLVAVHREIYPKADLTLLQKA
MSMEG_2965|M.smegmatis_MC2_155 ARISASRRVRARLARRMTAQRSAINPVLEPLVAVHREIYPKADLQLLQRA
TH_0745|M.thermoresistible__bu --TSASRRVRARLARRMTAQRSAINPVLEPLVAVHRQIYPKADLSLLQKA
MAB_2876c|M.abscessus_ATCC_199 GTMSASRRVRARLARRMTAQRGAVSPVLEPLIAVHREFYPKADRSVLQRA
Rv2583c|M.tuberculosis_H37Rv -SISASRRVRARLARRMTAQRSTTNPVLEPLVAVHREIYPKADLSILQRA
Mb2614c|M.bovis_AF2122/97 -SISASRRVRARLARRMTAQRSTTNPVLEPLVAVHREIYPKADLSILQRA
MLBr_00491|M.leprae_Br4923 -SSSASRRVRARLARRMTAQRSTISPVLEPLVAVHKEFYPKANLSIVQRA
MAV_3464|M.avium_104 -SSSASRRVRARLARRMTAQRSTLNPVLEPLVAMHREIYPKANVQLLQRA
MMAR_2124|M.marinum_M -TSSASRRVRARLARRITAQRSAINPVLEPLVAVHREVYPKADLSLLQRA
MUL_1729|M.ulcerans_Agy99 -TSSASRRVRARLARRITAQRSAINPVLEPLVAVHREVYPKADLSLLQRA
*************:*:**.: .******:*:*::.****: ::*:*
Mflv_3812|M.gilvum_PYR-GCK YEVAEQRHADQLRKSGDPYITHPLAVANILAELGMDTTTLIAALLHDTVE
Mvan_2587|M.vanbaalenii_PYR-1 YEVAEQRHADQLRKSGDPYITHPLAVANILAELGMDTTTLIAALLHDTVE
MSMEG_2965|M.smegmatis_MC2_155 YEVAEKRHADQLRKSGDPYITHPLAVANILAELGMDTTTLVAALLHDTVE
TH_0745|M.thermoresistible__bu YEVAERRHADQLRKSGDPYITHPLAVANILAELGMDTTTLVAALLHDTVE
MAB_2876c|M.abscessus_ATCC_199 YEVAESRHAEQFRKSGDPYITHPVAVANILAELGMDTTTLVAAILHDTVE
Rv2583c|M.tuberculosis_H37Rv YEVADQRHASQLRQSGDPYITHPLAVANILAELGMDTTTLVAALLHDTVE
Mb2614c|M.bovis_AF2122/97 YEVADQRHASQLRQSGDPYITHPLAVANILAELGMDTTTLVAALLHDTVE
MLBr_00491|M.leprae_Br4923 FEVADQRHASQLRRSGDPYITHPLAVANILAELGMDITTLVAALLHDTVE
MAV_3464|M.avium_104 FEVADQRHASQLRHSGDPYITHPLAVATILAELGMDSTTLVAALLHDTVE
MMAR_2124|M.marinum_M YEVADQRHAGQFRHSGDPYITHPLAVANILAELGMDSTTLVAALLHDTVE
MUL_1729|M.ulcerans_Agy99 YEVADQRHAGQFRHSGDPYITHPLAVANILAELGMDSTTLVAALLHDTVE
:***: *** *:*:*********:***.******** ***:**:******
Mflv_3812|M.gilvum_PYR-GCK DTGYTLEALTQEFGVEVGHLVDGVTKLDKVALGTAAEGETIRKMIIAMAR
Mvan_2587|M.vanbaalenii_PYR-1 DTGYTLEALTQEFGTEVGHLVDGVTKLDKVALGTAAEGETIRKMIIAMAR
MSMEG_2965|M.smegmatis_MC2_155 DTGYSLEALTADFGSEVGHLVDGVTKLDKVVLGSAAEGETIRKMIIAMAR
TH_0745|M.thermoresistible__bu DTGYSLEELTAEFGSEVAHLVDGVTKLDKVVLGSAAEGETIRKMIIAMAR
MAB_2876c|M.abscessus_ATCC_199 DTGYSLEQLTAEFGTEVAHLVDGVTKLDKVVLGNAAEGETIRKMIIAMAR
Rv2583c|M.tuberculosis_H37Rv DTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRKMITAMAR
Mb2614c|M.bovis_AF2122/97 DTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRKMITAMAR
MLBr_00491|M.leprae_Br4923 DTGYTLEALSEEFGDEVGHLVDGVTKLDRVVLGSAAEGETIRKMITAMAR
MAV_3464|M.avium_104 DTGYTLAQLSEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRKMITAMAR
MMAR_2124|M.marinum_M DTGYTLEALSEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRKMITAMAR
MUL_1729|M.ulcerans_Agy99 DTGYTLEALSEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRKMITAMAR
****:* *: :** **.**********:*.**.*********** ****
Mflv_3812|M.gilvum_PYR-GCK DPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMATV
Mvan_2587|M.vanbaalenii_PYR-1 DPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMATV
MSMEG_2965|M.smegmatis_MC2_155 DPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMATV
TH_0745|M.thermoresistible__bu DPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMATV
MAB_2876c|M.abscessus_ATCC_199 DPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMATV
Rv2583c|M.tuberculosis_H37Rv DPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASV
Mb2614c|M.bovis_AF2122/97 DPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASV
MLBr_00491|M.leprae_Br4923 DPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASV
MAV_3464|M.avium_104 DPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASV
MMAR_2124|M.marinum_M DPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASV
MUL_1729|M.ulcerans_Agy99 DPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASV
************************************************:*
Mflv_3812|M.gilvum_PYR-GCK KWELEDLSFAILHPKKYEEIVRLVADRAPSRDTYLAKVRAEITATLNASK
Mvan_2587|M.vanbaalenii_PYR-1 KWELEDLSFAILHPKKYEEIVRLVADRAPSRDTYLAKVRAEITATLNASK
MSMEG_2965|M.smegmatis_MC2_155 KWELEDLAFAILHPKKYEEIVRLVADRAPSRDTYLAKVRAEIGVALSAMK
TH_0745|M.thermoresistible__bu KWELEDLAFAILHPKKYEEIVRLVADRAPSRDTYLAKVRAEISNTLAKSK
MAB_2876c|M.abscessus_ATCC_199 KWELEDLSFAILHPKKYEEIVRLVADRAPSRDTYLAKVRAEIVATLNSSR
Rv2583c|M.tuberculosis_H37Rv KWELEDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASK
Mb2614c|M.bovis_AF2122/97 KWELEDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASK
MLBr_00491|M.leprae_Br4923 KWELEDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIISTLGASK
MAV_3464|M.avium_104 KWELEDLSFAILHPKKYDEIVRLVAGRAPSRDTYLAKVRAEIINTLNASK
MMAR_2124|M.marinum_M KWELEDLSFAILHPKKYDEIVRLVAGRAPSRDTYLAKVRAEIIATLSASK
MUL_1729|M.ulcerans_Agy99 KWELEDLSFAILHPKKYDEIVRLVAGRAPSRDTYLAKVRAEIIATLSASK
*******:*********:*******.**************** :* :
Mflv_3812|M.gilvum_PYR-GCK IKATVEGRPKHYWSIYQKMIVKGRDFDDIHDLVGVRILCDEVRDCYAAVG
Mvan_2587|M.vanbaalenii_PYR-1 INATVEGRPKHYWSIYQKMIVKGRDFDDIHDLVGVRILCDEVRDCYAAVG
MSMEG_2965|M.smegmatis_MC2_155 INAVVEGRPKHYWSIYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVG
TH_0745|M.thermoresistible__bu INAVVEGRPKHYWSIYQKMIVKGRDFDDIYDLVAVRILCDEIRDCYAAVG
MAB_2876c|M.abscessus_ATCC_199 ISATVEGRPKHYWSIYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVG
Rv2583c|M.tuberculosis_H37Rv IKATVEGRPKHYWSIYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVG
Mb2614c|M.bovis_AF2122/97 IKATVEGRPKHYWSIYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVG
MLBr_00491|M.leprae_Br4923 IKATVEGRPKHYWSIYQKMIVKGRDFDDIHDLVGIRILCDEIRDCYAAVG
MAV_3464|M.avium_104 IKATVEGRPKHYWSIYQKMIVKGRDFDDIHDLVGIRILCDEIRDCYAAVG
MMAR_2124|M.marinum_M IKATVEGRPKHYWSIYQKMIVKGRDFDDIHDLVGIRILCDEIRDCYAAVG
MUL_1729|M.ulcerans_Agy99 IKATVEGRPKHYWSIYQKMIVKGRDFDDIHDLVGIRILCDEIRDCYAAVG
*.*.*************************:***.:******:********
Mflv_3812|M.gilvum_PYR-GCK VVHSLWQPIAGRFKDYIAQPRFGVYQSLHTTVVGPEGKPLEVQIRTIDMH
Mvan_2587|M.vanbaalenii_PYR-1 VVHSLWQPIAGRFKDYIAQPRFGVYQSLHTTVVGPEGKPLEVQIRTIDMH
MSMEG_2965|M.smegmatis_MC2_155 VVHSLWQPMAGRFKDYIAQPRYGVYQSLHTTVVGPEGKPLEVQIRTREMH
TH_0745|M.thermoresistible__bu VVHSLWQPMAGRFKDYIAQPRYGVYQSLHTTVIGPEGKPLEVQIRTHDMH
MAB_2876c|M.abscessus_ATCC_199 VVHSLWQPMAGRFKDYIAQPRFGVYQSLHTTVVGPEGKPLEVQIRTRDMH
Rv2583c|M.tuberculosis_H37Rv VVHSLWQPMAGRFKDYIAQPRYGVYQSLHTTVVGPEGKPLEVQIRTRDMH
Mb2614c|M.bovis_AF2122/97 VVHSLWQPMAGRFKDYIAQPRYGVYQSLHTTVVGPEGKPLEVQIRTRDMH
MLBr_00491|M.leprae_Br4923 VVHSLWQPMAGRFKDYIAQPRYGVYQSLHTTVVGPEGKPLEVQIRTRDMH
MAV_3464|M.avium_104 VVHSLWQPMAGRFKDYIAQPRYGVYQSLHTTVVGPEGKPLEVQIRTRDMH
MMAR_2124|M.marinum_M VVHSLWQPMAGRFKDYIAQPRYGVYQSLHTTVVGPEGKPLEVQIRTRDMH
MUL_1729|M.ulcerans_Agy99 VVHSLWQPMAGRFKDYIAQPRYGVYESLHTTVVGPEGKPLEVQIRTRDMH
********:************:***:******:************* :**
Mflv_3812|M.gilvum_PYR-GCK KTAEYGIAAHWRYKEVKGRNGVPAGSAATEIDDMAWMRQLLDWQREAADP
Mvan_2587|M.vanbaalenii_PYR-1 KTAEYGIAAHWRYKEAKGRNGVPPSHAATEIDDMAWMRQLLDWQREAADP
MSMEG_2965|M.smegmatis_MC2_155 RTAEYGIAAHWRYKEAKGRNGVPHSHAAAEIDDMAWMRQLLDWQREAADP
TH_0745|M.thermoresistible__bu RTAEYGIAAHWRYKEARGRNGVPHPHAAAEIDDMAWMRQLLDWQREAADP
MAB_2876c|M.abscessus_ATCC_199 RTAEYGIAAHWRYKEAKGRNGVPPTHAAAEIDDMAWMRQLLDWQREAADP
Rv2583c|M.tuberculosis_H37Rv RTAEYGIAAHWRYKEAKGRNGVLHPHAAAEIDDMAWMRQLLDWQREAADP
Mb2614c|M.bovis_AF2122/97 RTAEYGIAAHWRYKEAKGRNGVLHPHAAAEIDDMAWMRQLLDWQREAADP
MLBr_00491|M.leprae_Br4923 RTAEYGIAAHWRYKEAKGRNGVLHPHAAAEIDDMAWMRQLLDWQREAAEP
MAV_3464|M.avium_104 RTAEYGIAAHWRYKEAKGRNGVPHPHAAAEIDDMAWMRQLLDWQREAADP
MMAR_2124|M.marinum_M RTAEYGIAAHWRYKEAKGRNGVPHPHAAAEIDDMAWMRQLLDWQREAADP
MUL_1729|M.ulcerans_Agy99 RTAEYGIAAHWRYKEAKGRNGVPHPHAAAEIDDMAWMRQLLDWQREAADP
:**************.:***** **:*******************:*
Mflv_3812|M.gilvum_PYR-GCK GEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHTEVGHRCI
Mvan_2587|M.vanbaalenii_PYR-1 GEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHTEVGHRCI
MSMEG_2965|M.smegmatis_MC2_155 GEFLESLRYDLATQEIFVFTPKGDVITLPAGSTPVDFAYAVHTEVGHRCI
TH_0745|M.thermoresistible__bu GEFLESLRYDLAVQEIFVFTPKGDVVTLPAGSTPVDFAYAVHTEVGHRCI
MAB_2876c|M.abscessus_ATCC_199 GEFLESLRYDLAVQEIFVFTPKGDVITLPAGSTPVDFAYAVHTEVGHRCI
Rv2583c|M.tuberculosis_H37Rv GEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHTEVGHRCI
Mb2614c|M.bovis_AF2122/97 GEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHTEVGHRCI
MLBr_00491|M.leprae_Br4923 GEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHTEVGHRCI
MAV_3464|M.avium_104 GEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPIDFAYAVHTEVGHRCI
MMAR_2124|M.marinum_M GEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHTEVGHRCI
MUL_1729|M.ulcerans_Agy99 GEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHTEVGHRCI
************.************:***:****:***************
Mflv_3812|M.gilvum_PYR-GCK GARVNGRLVALERKLENGEVVEVFTSKAQNAGPSRDWQGFVVSPRAKAKI
Mvan_2587|M.vanbaalenii_PYR-1 GARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQTFVVSPRAKAKI
MSMEG_2965|M.smegmatis_MC2_155 GARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQGFVVSPRAKTKI
TH_0745|M.thermoresistible__bu GARVNGRLVALERQLENGEVVEIFTSKAANAGPSRDWQSFVASPRAKAKI
MAB_2876c|M.abscessus_ATCC_199 GARVNGRLVALERKLENGEVVEVFTSKAANAGPSRDWQTFVVSPRAKAKI
Rv2583c|M.tuberculosis_H37Rv GARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPRAKTKI
Mb2614c|M.bovis_AF2122/97 GARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPRAKTKI
MLBr_00491|M.leprae_Br4923 GARVNGRLVALERKLENGEFVEIFTSKAPNAGPSRDWQQFVVSPRAKTKI
MAV_3464|M.avium_104 GARVNGRLVALERKLENGEVVEVFTSKAANAGPSRDWQQFVVSPRAKAKI
MMAR_2124|M.marinum_M GARVNGRLVALERQLENGEVVEVFTSKAPNAGPSRDWQQFVVSPRAKTKI
MUL_1729|M.ulcerans_Agy99 GARVNGRLVALERQLENGEVVDVFTSKAPNAGPSRDWQQFVVSPRAETKI
*************:*****.*::***** ********* **.****::**
Mflv_3812|M.gilvum_PYR-GCK RQWFAKERREEALDSGKEAIAREVRRGGLPLQRLMNAETMAALARELRYL
Mvan_2587|M.vanbaalenii_PYR-1 RQWFAKERREEALDSGKEAIAREVRRGGLPLQRLMNAETMAALARELRYA
MSMEG_2965|M.smegmatis_MC2_155 RQWFAKERREEALESGKDAIAREVRRGGLPLQRLMNAETMGALARELRYQ
TH_0745|M.thermoresistible__bu RQWFAKERREEALEAGKEAIAREVRRGGLPLQRLVTAEALSELAGELRYA
MAB_2876c|M.abscessus_ATCC_199 RQWFAKERREEALEAGKDAIAREVRRGGLPLQRLVNGEGMASLARELRYQ
Rv2583c|M.tuberculosis_H37Rv RQWFAKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYA
Mb2614c|M.bovis_AF2122/97 RQWFAKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYA
MLBr_00491|M.leprae_Br4923 RQWFAKERREEALEAGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYI
MAV_3464|M.avium_104 RQWFAKERREEALEAGKDAMAREVRRGGLPLQRLVNAESMSAVARELHYA
MMAR_2124|M.marinum_M RQWFAKERREEALEAGKEAIAREVRRGGLPLQRLVNGESMGAVARELHYT
MUL_1729|M.ulcerans_Agy99 RQWFAKERREEALEAGKEAIAREVRRGGLPLQRLVNGESMGAVARELHYT
*************::**:*:**************:..* :. :* **:*
Mflv_3812|M.gilvum_PYR-GCK DVSALYTAVGEGHVSARHVVQRLVAQLGGDDEAADELAERSTPATMPIRQ
Mvan_2587|M.vanbaalenii_PYR-1 DVSALYTAVGEGHVSARHVVQRLVAQLGGDDEAADEIAERSTPATMPVRQ
MSMEG_2965|M.smegmatis_MC2_155 DVSALYTAVGEGHVSARHVVQRLLAQFGGDDAAEDELAERSTPATMPMRQ
TH_0745|M.thermoresistible__bu DVSALYTAVGEGHVSARHVVQRLRARLSSDDEAEDELAERSTPSTMPVRQ
MAB_2876c|M.abscessus_ATCC_199 DTSQLYTAVGEGHVSARHVVQRLVAQLGGVDSAEEELAERSTPSTMPIRQ
Rv2583c|M.tuberculosis_H37Rv DVSALYTAIGEGHVSAKHVVQRLLAELGGIDQAEEELAERSTPATMPRRP
Mb2614c|M.bovis_AF2122/97 DVSALYTAIGEGHVSAKHVVQRLLAELGGIDQAEEELAERSTPATMPRRP
MLBr_00491|M.leprae_Br4923 DVSALYTAIGEGHVSARHVVQRLLAELGGIDQAEEELAERSTPTTMLRRQ
MAV_3464|M.avium_104 DVSALYTAIGEGHVSARHVVQRLLAELGGIDQAEEDLAERSTPTTMLRRP
MMAR_2124|M.marinum_M DVSALYTAIGEGHVSARHAMQRLLAELGGIDQAEEELAERATPTTIPRRP
MUL_1729|M.ulcerans_Agy99 DVSALYTAIGEGHVSARHAMQRLLAELGGIDQAEEELAERATPTTIPRRP
*.* ****:*******:*.:*** *.:.. * * :::***:**:*: *
Mflv_3812|M.gilvum_PYR-GCK RTSDDVGVAVPGAPGVLTKLAKCCTPVPGDNILGFVTRGGGVSVHRTDCT
Mvan_2587|M.vanbaalenii_PYR-1 RTSDDVGVAVPGAPGVLCKLAKCCTPVPGDNIMGFVTRGGGVSVHRTDCT
MSMEG_2965|M.smegmatis_MC2_155 RSNDDTGVAVPGAPGVLTKLAKCCTPVPGDTIMGFVTRGGGVSVHRTDCT
TH_0745|M.thermoresistible__bu RTPEDCGVSVPGAPGVLTKLAKCCTPVPGDNIMGFVTRGGGVSVHRTDCT
MAB_2876c|M.abscessus_ATCC_199 RRSDDVGVAVPGAPGVLTKLAKCCTPVPGDQILGFVTRGGGVSVHRTDCT
Rv2583c|M.tuberculosis_H37Rv RSTDDVGVSVPGAPGVLTKLAKCCTPVPGDVIMGFVTRGGGVSVHRTDCT
Mb2614c|M.bovis_AF2122/97 RSTDDVGVSVPGAPGVLTKLAKCCTPVPGDVIMGFVTRGGGVSVHRTDCT
MLBr_00491|M.leprae_Br4923 RSTDDVGVSVPGAPGVLTKLAKCCTPVPGDAIMGFVTRGGGVSVHRTDCT
MAV_3464|M.avium_104 RSSDDVGVSVPGAPGVLTKLAKCCTPVPGDQIMGFVTRGGGVSVHRTDCT
MMAR_2124|M.marinum_M RSSDDVGVSVPGAPGVMTKLAKCCTPVPGDNIMGFVTRGGGVSVHRTDCT
MUL_1729|M.ulcerans_Agy99 RSSDDVGVSVPGAPGVMTKLAKCCTPVPGDNIMGFVTRGGGVSVHRTDCT
* :* **:*******: ************ *:*****************
Mflv_3812|M.gilvum_PYR-GCK NAASLEQQSERIIDVQWAPSPSSVFLVAIQVEALDRHRLLSDVTRVLADE
Mvan_2587|M.vanbaalenii_PYR-1 NAASLQDQSERIIEVQWAPSPSSVFLVAIQVEALDRHRLLSDVTRVLADE
MSMEG_2965|M.smegmatis_MC2_155 NAESLQQQSERIIEVNWAPSPSSVFLVAIQVEALDRHRLLSDVTRVLADE
TH_0745|M.thermoresistible__bu NAAELQKQSERIIDVKWAPSPSSVFLVAIQVEALDRHRLLSDVTRVLADE
MAB_2876c|M.abscessus_ATCC_199 NAESLQQQSERIIEVHWAPSASSVFLVAIQVEALDRHRLLSDVTRALADE
Rv2583c|M.tuberculosis_H37Rv NAASLQQQAERIIEVLWAPSPSSVFLVAIQVEALDRHRLLSDVTRALADE
Mb2614c|M.bovis_AF2122/97 NAASLQQQAERIIEVLWAPSPSSVFLVAIQVEALDRHRLLSDVTRALADE
MLBr_00491|M.leprae_Br4923 NTASLQQQAERIIEVLWAPSSSSVFLVAIQVEALDRHRLLLDITRALADE
MAV_3464|M.avium_104 NAASLQQQSERIIEVHWAPSPSSVFLVAIQVEALDRHRLLSDVTRVLADE
MMAR_2124|M.marinum_M NAESLKQQSERIIEVHWAPSPSSVFLVAIQVEALDRHRLLSDVTRVLADE
MUL_1729|M.ulcerans_Agy99 NAESLKQQSERIIEVHWAPSPSSVFLVAIQVEALDRHRLLSDVTRVLADE
*: .*:.*:****:* ****.******************* *:**.****
Mflv_3812|M.gilvum_PYR-GCK KVNILSASVTTSNDRVAISRFTFEMGDPKHLGHVLNVVRNVEGVYDVYRV
Mvan_2587|M.vanbaalenii_PYR-1 KVNILSASVTTSNDRVAISRFTFEMGDPKHLGHVLNVVRNVEGVYDVYRV
MSMEG_2965|M.smegmatis_MC2_155 KVNILSASVTTSNDRVAISRFTFEMGDPKHLGHLLSVVRNVEGVYDVYRV
TH_0745|M.thermoresistible__bu KVNILSASVTTSNDRVAISRFTFEMGDPKHLGHVLNVVRNVEGVYDVYRV
MAB_2876c|M.abscessus_ATCC_199 RVNILSASVTTSNDRVAISRFTFEMGDPKHLGHVLNVVRNVEGVYDVYRV
Rv2583c|M.tuberculosis_H37Rv KVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLNAVRNVEGVYDVYRV
Mb2614c|M.bovis_AF2122/97 KVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLNAVRNVEGVYDVYRV
MLBr_00491|M.leprae_Br4923 RVDILSASVTTSGDRVAISRFTFEMGDPKHLGHLLNVVRNVEGVYDVYRV
MAV_3464|M.avium_104 KVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLNVVRNVEGVYDVYRV
MMAR_2124|M.marinum_M KVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLNVVRNVEGVYDVYRV
MUL_1729|M.ulcerans_Agy99 KVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLNVVRNVEGVYDVYRV
:*:*********.********************:*..*************
Mflv_3812|M.gilvum_PYR-GCK TSAA
Mvan_2587|M.vanbaalenii_PYR-1 TSAA
MSMEG_2965|M.smegmatis_MC2_155 TSAA
TH_0745|M.thermoresistible__bu TSAA
MAB_2876c|M.abscessus_ATCC_199 TSAA
Rv2583c|M.tuberculosis_H37Rv TSAA
Mb2614c|M.bovis_AF2122/97 TSAA
MLBr_00491|M.leprae_Br4923 MSAS
MAV_3464|M.avium_104 TSAA
MMAR_2124|M.marinum_M TSAA
MUL_1729|M.ulcerans_Agy99 TSAA
**: