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ADEHVPSENQVAVESLPALSEPGPVTESLRVSGGTMSASRRVRARLARRMTAQRGAVSPVLEPLIAVHRE FYPKADRSVLQRAYEVAESRHAEQFRKSGDPYITHPVAVANILAELGMDTTTLVAAILHDTVEDTGYSLE QLTAEFGTEVAHLVDGVTKLDKVVLGNAAEGETIRKMIIAMARDPRVLVIKVADRLHNMRTMRFLPPEKQ ARKARETLEVIAPLAHRLGMATVKWELEDLSFAILHPKKYEEIVRLVADRAPSRDTYLAKVRAEIVATLN SSRISATVEGRPKHYWSIYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYI AQPRFGVYQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVPPTHAAAEIDDMAWM RQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPAGSTPVDFAYAVHTEVGHRCIGARVNGR LVALERKLENGEVVEVFTSKAANAGPSRDWQTFVVSPRAKAKIRQWFAKERREEALEAGKDAIAREVRRG GLPLQRLVNGEGMASLARELRYQDTSQLYTAVGEGHVSARHVVQRLVAQLGGVDSAEEELAERSTPSTMP IRQRRSDDVGVAVPGAPGVLTKLAKCCTPVPGDQILGFVTRGGGVSVHRTDCTNAESLQQQSERIIEVHW APSASSVFLVAIQVEALDRHRLLSDVTRALADERVNILSASVTTSNDRVAISRFTFEMGDPKHLGHVLNV VRNVEGVYDVYRVTSAA*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. abscessus ATCC 19977 | MAB_2876c | - | - | 100% (788) | GTP pyrophosphokinase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2614c | relA | 0.0 | 88.62% (782) | GTP pyrophosphokinase |
M. gilvum PYR-GCK | Mflv_3812 | - | 0.0 | 89.32% (777) | (p)ppGpp synthetase I, SpoT/RelA |
M. tuberculosis H37Rv | Rv2583c | relA | 0.0 | 88.62% (782) | GTP pyrophosphokinase |
M. leprae Br4923 | MLBr_00491 | relA | 0.0 | 86.33% (790) | putative GTP pyrophosphokinase |
M. marinum M | MMAR_2124 | relA | 0.0 | 87.34% (790) | GTP pyrophosphokinase RelA |
M. avium 104 | MAV_3464 | relA | 0.0 | 88.85% (771) | GTP pyrophosphokinase |
M. smegmatis MC2 155 | MSMEG_2965 | relA | 0.0 | 88.04% (794) | GTP pyrophosphokinase |
M. thermoresistible (build 8) | TH_0745 | relA | 0.0 | 90.41% (751) | PROBABLE GTP PYROPHOSPHOKINASE RELA (ATP:GTP |
M. ulcerans Agy99 | MUL_1729 | relA | 0.0 | 86.96% (790) | GTP pyrophosphokinase RelA |
M. vanbaalenii PYR-1 | Mvan_2587 | - | 0.0 | 90.45% (764) | (p)ppGpp synthetase I, SpoT/RelA |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_3812|M.gilvum_PYR-GCK ---MADKVRTDPGSGQAVQTPP--------PAASASPET---QPMEIVKP Mvan_2587|M.vanbaalenii_PYR-1 ---MADKVRTEPVAGQAVQSPP--------PPV-ATPET---QPMELPKP MSMEG_2965|M.smegmatis_MC2_155 ---MVD----EPGKGQAVQSPPAVPETVPKPPSGTAPTTTPAAPSTSSET TH_0745|M.thermoresistible__bu -VMMAD----DPRSTQAVQPPQ--------------------EPVEPPKP MAB_2876c|M.abscessus_ATCC_199 ---MAD-EHVPSENQVAVESLP------------ALSEPGPVTESLRVSG Mb2614c|M.bovis_AF2122/97 ---MAE----DQLTAQAVAPPTE-----ASAALEPALETPES-PVETLKT Rv2583c|M.tuberculosis_H37Rv ---MAE----DQLTAQAVAPPTE-----ASAALEPALETPES-PVETLKT MLBr_00491|M.leprae_Br4923 ---MAD----DQGTAQALQP--------VQVVPGPAVEAPET-PVETLKT MAV_3464|M.avium_104 MSIVAE----ENSAAQALDAP-------AESPPNPVIETPEP-PTESLKT MMAR_2124|M.marinum_M ---MAD----DQSTTQAVVP---------SVESPPVVEAPEAAPAETLKT MUL_1729|M.ulcerans_Agy99 MTTVAD----DQSTTQAVVP---------SVESPPVVEAPEAAPAETLKT :.: *: . . Mflv_3812|M.gilvum_PYR-GCK APTSASRRVRARLARRMTSQRSTVNPVLEPLVAVHREIYPKADLTLLQKA Mvan_2587|M.vanbaalenii_PYR-1 -PTSASRRVRARLARRMTSQRSTINPVLEPLVAVHREIYPKADLTLLQKA MSMEG_2965|M.smegmatis_MC2_155 ARISASRRVRARLARRMTAQRSAINPVLEPLVAVHREIYPKADLQLLQRA TH_0745|M.thermoresistible__bu --TSASRRVRARLARRMTAQRSAINPVLEPLVAVHRQIYPKADLSLLQKA MAB_2876c|M.abscessus_ATCC_199 GTMSASRRVRARLARRMTAQRGAVSPVLEPLIAVHREFYPKADRSVLQRA Mb2614c|M.bovis_AF2122/97 -SISASRRVRARLARRMTAQRSTTNPVLEPLVAVHREIYPKADLSILQRA Rv2583c|M.tuberculosis_H37Rv -SISASRRVRARLARRMTAQRSTTNPVLEPLVAVHREIYPKADLSILQRA MLBr_00491|M.leprae_Br4923 -SSSASRRVRARLARRMTAQRSTISPVLEPLVAVHKEFYPKANLSIVQRA MAV_3464|M.avium_104 -SSSASRRVRARLARRMTAQRSTLNPVLEPLVAMHREIYPKANVQLLQRA MMAR_2124|M.marinum_M -TSSASRRVRARLARRITAQRSAINPVLEPLVAVHREVYPKADLSLLQRA MUL_1729|M.ulcerans_Agy99 -TSSASRRVRARLARRITAQRSAINPVLEPLVAVHREVYPKADLSLLQRA *************:*:**.: .******:*:*::.****: ::*:* Mflv_3812|M.gilvum_PYR-GCK YEVAEQRHADQLRKSGDPYITHPLAVANILAELGMDTTTLIAALLHDTVE Mvan_2587|M.vanbaalenii_PYR-1 YEVAEQRHADQLRKSGDPYITHPLAVANILAELGMDTTTLIAALLHDTVE MSMEG_2965|M.smegmatis_MC2_155 YEVAEKRHADQLRKSGDPYITHPLAVANILAELGMDTTTLVAALLHDTVE TH_0745|M.thermoresistible__bu YEVAERRHADQLRKSGDPYITHPLAVANILAELGMDTTTLVAALLHDTVE MAB_2876c|M.abscessus_ATCC_199 YEVAESRHAEQFRKSGDPYITHPVAVANILAELGMDTTTLVAAILHDTVE Mb2614c|M.bovis_AF2122/97 YEVADQRHASQLRQSGDPYITHPLAVANILAELGMDTTTLVAALLHDTVE Rv2583c|M.tuberculosis_H37Rv YEVADQRHASQLRQSGDPYITHPLAVANILAELGMDTTTLVAALLHDTVE MLBr_00491|M.leprae_Br4923 FEVADQRHASQLRRSGDPYITHPLAVANILAELGMDITTLVAALLHDTVE MAV_3464|M.avium_104 FEVADQRHASQLRHSGDPYITHPLAVATILAELGMDSTTLVAALLHDTVE MMAR_2124|M.marinum_M YEVADQRHAGQFRHSGDPYITHPLAVANILAELGMDSTTLVAALLHDTVE MUL_1729|M.ulcerans_Agy99 YEVADQRHAGQFRHSGDPYITHPLAVANILAELGMDSTTLVAALLHDTVE :***: *** *:*:*********:***.******** ***:**:****** Mflv_3812|M.gilvum_PYR-GCK DTGYTLEALTQEFGVEVGHLVDGVTKLDKVALGTAAEGETIRKMIIAMAR Mvan_2587|M.vanbaalenii_PYR-1 DTGYTLEALTQEFGTEVGHLVDGVTKLDKVALGTAAEGETIRKMIIAMAR MSMEG_2965|M.smegmatis_MC2_155 DTGYSLEALTADFGSEVGHLVDGVTKLDKVVLGSAAEGETIRKMIIAMAR TH_0745|M.thermoresistible__bu DTGYSLEELTAEFGSEVAHLVDGVTKLDKVVLGSAAEGETIRKMIIAMAR MAB_2876c|M.abscessus_ATCC_199 DTGYSLEQLTAEFGTEVAHLVDGVTKLDKVVLGNAAEGETIRKMIIAMAR Mb2614c|M.bovis_AF2122/97 DTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRKMITAMAR Rv2583c|M.tuberculosis_H37Rv DTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRKMITAMAR MLBr_00491|M.leprae_Br4923 DTGYTLEALSEEFGDEVGHLVDGVTKLDRVVLGSAAEGETIRKMITAMAR MAV_3464|M.avium_104 DTGYTLAQLSEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRKMITAMAR MMAR_2124|M.marinum_M DTGYTLEALSEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRKMITAMAR MUL_1729|M.ulcerans_Agy99 DTGYTLEALSEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRKMITAMAR ****:* *: :** **.**********:*.**.*********** **** Mflv_3812|M.gilvum_PYR-GCK DPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMATV Mvan_2587|M.vanbaalenii_PYR-1 DPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMATV MSMEG_2965|M.smegmatis_MC2_155 DPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMATV TH_0745|M.thermoresistible__bu DPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMATV MAB_2876c|M.abscessus_ATCC_199 DPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMATV Mb2614c|M.bovis_AF2122/97 DPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASV Rv2583c|M.tuberculosis_H37Rv DPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASV MLBr_00491|M.leprae_Br4923 DPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASV MAV_3464|M.avium_104 DPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASV MMAR_2124|M.marinum_M DPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASV MUL_1729|M.ulcerans_Agy99 DPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASV ************************************************:* Mflv_3812|M.gilvum_PYR-GCK KWELEDLSFAILHPKKYEEIVRLVADRAPSRDTYLAKVRAEITATLNASK Mvan_2587|M.vanbaalenii_PYR-1 KWELEDLSFAILHPKKYEEIVRLVADRAPSRDTYLAKVRAEITATLNASK MSMEG_2965|M.smegmatis_MC2_155 KWELEDLAFAILHPKKYEEIVRLVADRAPSRDTYLAKVRAEIGVALSAMK TH_0745|M.thermoresistible__bu KWELEDLAFAILHPKKYEEIVRLVADRAPSRDTYLAKVRAEISNTLAKSK MAB_2876c|M.abscessus_ATCC_199 KWELEDLSFAILHPKKYEEIVRLVADRAPSRDTYLAKVRAEIVATLNSSR Mb2614c|M.bovis_AF2122/97 KWELEDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASK Rv2583c|M.tuberculosis_H37Rv KWELEDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASK MLBr_00491|M.leprae_Br4923 KWELEDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIISTLGASK MAV_3464|M.avium_104 KWELEDLSFAILHPKKYDEIVRLVAGRAPSRDTYLAKVRAEIINTLNASK MMAR_2124|M.marinum_M KWELEDLSFAILHPKKYDEIVRLVAGRAPSRDTYLAKVRAEIIATLSASK MUL_1729|M.ulcerans_Agy99 KWELEDLSFAILHPKKYDEIVRLVAGRAPSRDTYLAKVRAEIIATLSASK *******:*********:*******.**************** :* : Mflv_3812|M.gilvum_PYR-GCK IKATVEGRPKHYWSIYQKMIVKGRDFDDIHDLVGVRILCDEVRDCYAAVG Mvan_2587|M.vanbaalenii_PYR-1 INATVEGRPKHYWSIYQKMIVKGRDFDDIHDLVGVRILCDEVRDCYAAVG MSMEG_2965|M.smegmatis_MC2_155 INAVVEGRPKHYWSIYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVG TH_0745|M.thermoresistible__bu INAVVEGRPKHYWSIYQKMIVKGRDFDDIYDLVAVRILCDEIRDCYAAVG MAB_2876c|M.abscessus_ATCC_199 ISATVEGRPKHYWSIYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVG Mb2614c|M.bovis_AF2122/97 IKATVEGRPKHYWSIYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVG Rv2583c|M.tuberculosis_H37Rv IKATVEGRPKHYWSIYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVG MLBr_00491|M.leprae_Br4923 IKATVEGRPKHYWSIYQKMIVKGRDFDDIHDLVGIRILCDEIRDCYAAVG MAV_3464|M.avium_104 IKATVEGRPKHYWSIYQKMIVKGRDFDDIHDLVGIRILCDEIRDCYAAVG MMAR_2124|M.marinum_M IKATVEGRPKHYWSIYQKMIVKGRDFDDIHDLVGIRILCDEIRDCYAAVG MUL_1729|M.ulcerans_Agy99 IKATVEGRPKHYWSIYQKMIVKGRDFDDIHDLVGIRILCDEIRDCYAAVG *.*.*************************:***.:******:******** Mflv_3812|M.gilvum_PYR-GCK VVHSLWQPIAGRFKDYIAQPRFGVYQSLHTTVVGPEGKPLEVQIRTIDMH Mvan_2587|M.vanbaalenii_PYR-1 VVHSLWQPIAGRFKDYIAQPRFGVYQSLHTTVVGPEGKPLEVQIRTIDMH MSMEG_2965|M.smegmatis_MC2_155 VVHSLWQPMAGRFKDYIAQPRYGVYQSLHTTVVGPEGKPLEVQIRTREMH TH_0745|M.thermoresistible__bu VVHSLWQPMAGRFKDYIAQPRYGVYQSLHTTVIGPEGKPLEVQIRTHDMH MAB_2876c|M.abscessus_ATCC_199 VVHSLWQPMAGRFKDYIAQPRFGVYQSLHTTVVGPEGKPLEVQIRTRDMH Mb2614c|M.bovis_AF2122/97 VVHSLWQPMAGRFKDYIAQPRYGVYQSLHTTVVGPEGKPLEVQIRTRDMH Rv2583c|M.tuberculosis_H37Rv VVHSLWQPMAGRFKDYIAQPRYGVYQSLHTTVVGPEGKPLEVQIRTRDMH MLBr_00491|M.leprae_Br4923 VVHSLWQPMAGRFKDYIAQPRYGVYQSLHTTVVGPEGKPLEVQIRTRDMH MAV_3464|M.avium_104 VVHSLWQPMAGRFKDYIAQPRYGVYQSLHTTVVGPEGKPLEVQIRTRDMH MMAR_2124|M.marinum_M VVHSLWQPMAGRFKDYIAQPRYGVYQSLHTTVVGPEGKPLEVQIRTRDMH MUL_1729|M.ulcerans_Agy99 VVHSLWQPMAGRFKDYIAQPRYGVYESLHTTVVGPEGKPLEVQIRTRDMH ********:************:***:******:************* :** Mflv_3812|M.gilvum_PYR-GCK KTAEYGIAAHWRYKEVKGRNGVPAGSAATEIDDMAWMRQLLDWQREAADP Mvan_2587|M.vanbaalenii_PYR-1 KTAEYGIAAHWRYKEAKGRNGVPPSHAATEIDDMAWMRQLLDWQREAADP MSMEG_2965|M.smegmatis_MC2_155 RTAEYGIAAHWRYKEAKGRNGVPHSHAAAEIDDMAWMRQLLDWQREAADP TH_0745|M.thermoresistible__bu RTAEYGIAAHWRYKEARGRNGVPHPHAAAEIDDMAWMRQLLDWQREAADP MAB_2876c|M.abscessus_ATCC_199 RTAEYGIAAHWRYKEAKGRNGVPPTHAAAEIDDMAWMRQLLDWQREAADP Mb2614c|M.bovis_AF2122/97 RTAEYGIAAHWRYKEAKGRNGVLHPHAAAEIDDMAWMRQLLDWQREAADP Rv2583c|M.tuberculosis_H37Rv RTAEYGIAAHWRYKEAKGRNGVLHPHAAAEIDDMAWMRQLLDWQREAADP MLBr_00491|M.leprae_Br4923 RTAEYGIAAHWRYKEAKGRNGVLHPHAAAEIDDMAWMRQLLDWQREAAEP MAV_3464|M.avium_104 RTAEYGIAAHWRYKEAKGRNGVPHPHAAAEIDDMAWMRQLLDWQREAADP MMAR_2124|M.marinum_M RTAEYGIAAHWRYKEAKGRNGVPHPHAAAEIDDMAWMRQLLDWQREAADP MUL_1729|M.ulcerans_Agy99 RTAEYGIAAHWRYKEAKGRNGVPHPHAAAEIDDMAWMRQLLDWQREAADP :**************.:***** **:*******************:* Mflv_3812|M.gilvum_PYR-GCK GEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHTEVGHRCI Mvan_2587|M.vanbaalenii_PYR-1 GEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHTEVGHRCI MSMEG_2965|M.smegmatis_MC2_155 GEFLESLRYDLATQEIFVFTPKGDVITLPAGSTPVDFAYAVHTEVGHRCI TH_0745|M.thermoresistible__bu GEFLESLRYDLAVQEIFVFTPKGDVVTLPAGSTPVDFAYAVHTEVGHRCI MAB_2876c|M.abscessus_ATCC_199 GEFLESLRYDLAVQEIFVFTPKGDVITLPAGSTPVDFAYAVHTEVGHRCI Mb2614c|M.bovis_AF2122/97 GEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHTEVGHRCI Rv2583c|M.tuberculosis_H37Rv GEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHTEVGHRCI MLBr_00491|M.leprae_Br4923 GEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHTEVGHRCI MAV_3464|M.avium_104 GEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPIDFAYAVHTEVGHRCI MMAR_2124|M.marinum_M GEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHTEVGHRCI MUL_1729|M.ulcerans_Agy99 GEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHTEVGHRCI ************.************:***:****:*************** Mflv_3812|M.gilvum_PYR-GCK GARVNGRLVALERKLENGEVVEVFTSKAQNAGPSRDWQGFVVSPRAKAKI Mvan_2587|M.vanbaalenii_PYR-1 GARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQTFVVSPRAKAKI MSMEG_2965|M.smegmatis_MC2_155 GARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQGFVVSPRAKTKI TH_0745|M.thermoresistible__bu GARVNGRLVALERQLENGEVVEIFTSKAANAGPSRDWQSFVASPRAKAKI MAB_2876c|M.abscessus_ATCC_199 GARVNGRLVALERKLENGEVVEVFTSKAANAGPSRDWQTFVVSPRAKAKI Mb2614c|M.bovis_AF2122/97 GARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPRAKTKI Rv2583c|M.tuberculosis_H37Rv GARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPRAKTKI MLBr_00491|M.leprae_Br4923 GARVNGRLVALERKLENGEFVEIFTSKAPNAGPSRDWQQFVVSPRAKTKI MAV_3464|M.avium_104 GARVNGRLVALERKLENGEVVEVFTSKAANAGPSRDWQQFVVSPRAKAKI MMAR_2124|M.marinum_M GARVNGRLVALERQLENGEVVEVFTSKAPNAGPSRDWQQFVVSPRAKTKI MUL_1729|M.ulcerans_Agy99 GARVNGRLVALERQLENGEVVDVFTSKAPNAGPSRDWQQFVVSPRAETKI *************:*****.*::***** ********* **.****::** Mflv_3812|M.gilvum_PYR-GCK RQWFAKERREEALDSGKEAIAREVRRGGLPLQRLMNAETMAALARELRYL Mvan_2587|M.vanbaalenii_PYR-1 RQWFAKERREEALDSGKEAIAREVRRGGLPLQRLMNAETMAALARELRYA MSMEG_2965|M.smegmatis_MC2_155 RQWFAKERREEALESGKDAIAREVRRGGLPLQRLMNAETMGALARELRYQ TH_0745|M.thermoresistible__bu RQWFAKERREEALEAGKEAIAREVRRGGLPLQRLVTAEALSELAGELRYA MAB_2876c|M.abscessus_ATCC_199 RQWFAKERREEALEAGKDAIAREVRRGGLPLQRLVNGEGMASLARELRYQ Mb2614c|M.bovis_AF2122/97 RQWFAKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYA Rv2583c|M.tuberculosis_H37Rv RQWFAKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYA MLBr_00491|M.leprae_Br4923 RQWFAKERREEALEAGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYI MAV_3464|M.avium_104 RQWFAKERREEALEAGKDAMAREVRRGGLPLQRLVNAESMSAVARELHYA MMAR_2124|M.marinum_M RQWFAKERREEALEAGKEAIAREVRRGGLPLQRLVNGESMGAVARELHYT MUL_1729|M.ulcerans_Agy99 RQWFAKERREEALEAGKEAIAREVRRGGLPLQRLVNGESMGAVARELHYT *************::**:*:**************:..* :. :* **:* Mflv_3812|M.gilvum_PYR-GCK DVSALYTAVGEGHVSARHVVQRLVAQLGGDDEAADELAERSTPATMPIRQ Mvan_2587|M.vanbaalenii_PYR-1 DVSALYTAVGEGHVSARHVVQRLVAQLGGDDEAADEIAERSTPATMPVRQ MSMEG_2965|M.smegmatis_MC2_155 DVSALYTAVGEGHVSARHVVQRLLAQFGGDDAAEDELAERSTPATMPMRQ TH_0745|M.thermoresistible__bu DVSALYTAVGEGHVSARHVVQRLRARLSSDDEAEDELAERSTPSTMPVRQ MAB_2876c|M.abscessus_ATCC_199 DTSQLYTAVGEGHVSARHVVQRLVAQLGGVDSAEEELAERSTPSTMPIRQ Mb2614c|M.bovis_AF2122/97 DVSALYTAIGEGHVSAKHVVQRLLAELGGIDQAEEELAERSTPATMPRRP Rv2583c|M.tuberculosis_H37Rv DVSALYTAIGEGHVSAKHVVQRLLAELGGIDQAEEELAERSTPATMPRRP MLBr_00491|M.leprae_Br4923 DVSALYTAIGEGHVSARHVVQRLLAELGGIDQAEEELAERSTPTTMLRRQ MAV_3464|M.avium_104 DVSALYTAIGEGHVSARHVVQRLLAELGGIDQAEEDLAERSTPTTMLRRP MMAR_2124|M.marinum_M DVSALYTAIGEGHVSARHAMQRLLAELGGIDQAEEELAERATPTTIPRRP MUL_1729|M.ulcerans_Agy99 DVSALYTAIGEGHVSARHAMQRLLAELGGIDQAEEELAERATPTTIPRRP *.* ****:*******:*.:*** *.:.. * * :::***:**:*: * Mflv_3812|M.gilvum_PYR-GCK RTSDDVGVAVPGAPGVLTKLAKCCTPVPGDNILGFVTRGGGVSVHRTDCT Mvan_2587|M.vanbaalenii_PYR-1 RTSDDVGVAVPGAPGVLCKLAKCCTPVPGDNIMGFVTRGGGVSVHRTDCT MSMEG_2965|M.smegmatis_MC2_155 RSNDDTGVAVPGAPGVLTKLAKCCTPVPGDTIMGFVTRGGGVSVHRTDCT TH_0745|M.thermoresistible__bu RTPEDCGVSVPGAPGVLTKLAKCCTPVPGDNIMGFVTRGGGVSVHRTDCT MAB_2876c|M.abscessus_ATCC_199 RRSDDVGVAVPGAPGVLTKLAKCCTPVPGDQILGFVTRGGGVSVHRTDCT Mb2614c|M.bovis_AF2122/97 RSTDDVGVSVPGAPGVLTKLAKCCTPVPGDVIMGFVTRGGGVSVHRTDCT Rv2583c|M.tuberculosis_H37Rv RSTDDVGVSVPGAPGVLTKLAKCCTPVPGDVIMGFVTRGGGVSVHRTDCT MLBr_00491|M.leprae_Br4923 RSTDDVGVSVPGAPGVLTKLAKCCTPVPGDAIMGFVTRGGGVSVHRTDCT MAV_3464|M.avium_104 RSSDDVGVSVPGAPGVLTKLAKCCTPVPGDQIMGFVTRGGGVSVHRTDCT MMAR_2124|M.marinum_M RSSDDVGVSVPGAPGVMTKLAKCCTPVPGDNIMGFVTRGGGVSVHRTDCT MUL_1729|M.ulcerans_Agy99 RSSDDVGVSVPGAPGVMTKLAKCCTPVPGDNIMGFVTRGGGVSVHRTDCT * :* **:*******: ************ *:***************** Mflv_3812|M.gilvum_PYR-GCK NAASLEQQSERIIDVQWAPSPSSVFLVAIQVEALDRHRLLSDVTRVLADE Mvan_2587|M.vanbaalenii_PYR-1 NAASLQDQSERIIEVQWAPSPSSVFLVAIQVEALDRHRLLSDVTRVLADE MSMEG_2965|M.smegmatis_MC2_155 NAESLQQQSERIIEVNWAPSPSSVFLVAIQVEALDRHRLLSDVTRVLADE TH_0745|M.thermoresistible__bu NAAELQKQSERIIDVKWAPSPSSVFLVAIQVEALDRHRLLSDVTRVLADE MAB_2876c|M.abscessus_ATCC_199 NAESLQQQSERIIEVHWAPSASSVFLVAIQVEALDRHRLLSDVTRALADE Mb2614c|M.bovis_AF2122/97 NAASLQQQAERIIEVLWAPSPSSVFLVAIQVEALDRHRLLSDVTRALADE Rv2583c|M.tuberculosis_H37Rv NAASLQQQAERIIEVLWAPSPSSVFLVAIQVEALDRHRLLSDVTRALADE MLBr_00491|M.leprae_Br4923 NTASLQQQAERIIEVLWAPSSSSVFLVAIQVEALDRHRLLLDITRALADE MAV_3464|M.avium_104 NAASLQQQSERIIEVHWAPSPSSVFLVAIQVEALDRHRLLSDVTRVLADE MMAR_2124|M.marinum_M NAESLKQQSERIIEVHWAPSPSSVFLVAIQVEALDRHRLLSDVTRVLADE MUL_1729|M.ulcerans_Agy99 NAESLKQQSERIIEVHWAPSPSSVFLVAIQVEALDRHRLLSDVTRVLADE *: .*:.*:****:* ****.******************* *:**.**** Mflv_3812|M.gilvum_PYR-GCK KVNILSASVTTSNDRVAISRFTFEMGDPKHLGHVLNVVRNVEGVYDVYRV Mvan_2587|M.vanbaalenii_PYR-1 KVNILSASVTTSNDRVAISRFTFEMGDPKHLGHVLNVVRNVEGVYDVYRV MSMEG_2965|M.smegmatis_MC2_155 KVNILSASVTTSNDRVAISRFTFEMGDPKHLGHLLSVVRNVEGVYDVYRV TH_0745|M.thermoresistible__bu KVNILSASVTTSNDRVAISRFTFEMGDPKHLGHVLNVVRNVEGVYDVYRV MAB_2876c|M.abscessus_ATCC_199 RVNILSASVTTSNDRVAISRFTFEMGDPKHLGHVLNVVRNVEGVYDVYRV Mb2614c|M.bovis_AF2122/97 KVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLNAVRNVEGVYDVYRV Rv2583c|M.tuberculosis_H37Rv KVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLNAVRNVEGVYDVYRV MLBr_00491|M.leprae_Br4923 RVDILSASVTTSGDRVAISRFTFEMGDPKHLGHLLNVVRNVEGVYDVYRV MAV_3464|M.avium_104 KVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLNVVRNVEGVYDVYRV MMAR_2124|M.marinum_M KVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLNVVRNVEGVYDVYRV MUL_1729|M.ulcerans_Agy99 KVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLNVVRNVEGVYDVYRV :*:*********.********************:*..************* Mflv_3812|M.gilvum_PYR-GCK TSAA Mvan_2587|M.vanbaalenii_PYR-1 TSAA MSMEG_2965|M.smegmatis_MC2_155 TSAA TH_0745|M.thermoresistible__bu TSAA MAB_2876c|M.abscessus_ATCC_199 TSAA Mb2614c|M.bovis_AF2122/97 TSAA Rv2583c|M.tuberculosis_H37Rv TSAA MLBr_00491|M.leprae_Br4923 MSAS MAV_3464|M.avium_104 TSAA MMAR_2124|M.marinum_M TSAA MUL_1729|M.ulcerans_Agy99 TSAA **: