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MTFNEGVQIDTSTTSTSGSGGGRRLAIGGGLGGLLVVVVAMLLGVDPGGVLSQQPLDTRDHVAPGFDLSQ CRTGADANRFVQCRVVATGNSVDAVWKPLLPGYTRPHMRLFSGQVGTGCGPASSEVGPFYCPVDKTAYFD TDFFQVLVTQFGSSGGPFAEEYVVAHEYGHHVQNLLGVLGRAQQGAQGAAGSGVRTELQADCYAGVWAYY ASTVKQESTGVPYLEPLSDKDIQDALAAAAAVGDDRIQQQTTGRTNPETWTHGSAAQRQKWFTVGYQTGD PNICDTFSAADLG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2575 | - | - | 100% (293) | POSSIBLE CONSERVED MEMBRANE GLYCINE RICH PROTEIN |
| M. tuberculosis H37Rv | Rv0419 | lpqM | 2e-05 | 25.63% (199) | lipoprotein peptidase LpqM |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2605 | - | 1e-174 | 100.00% (293) | hypothetical protein Mb2605 |
| M. gilvum PYR-GCK | Mflv_3788 | - | 1e-127 | 73.99% (296) | protein of unknown function, zinc metallopeptidase putative |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2867 | - | 1e-114 | 66.67% (294) | hypothetical protein MAB_2867 |
| M. marinum M | MMAR_2155 | - | 1e-151 | 85.03% (294) | membrane glycine rich protein |
| M. avium 104 | MAV_3451 | - | 1e-138 | 77.82% (293) | metallopeptidase, zinc binding |
| M. smegmatis MC2 155 | MSMEG_3000 | - | 1e-135 | 77.44% (297) | metallopeptidase, zinc binding |
| M. thermoresistible (build 8) | TH_0541 | - | 1e-125 | 73.70% (289) | POSSIBLE CONSERVED MEMBRANE GLYCINE RICH PROTEIN |
| M. ulcerans Agy99 | MUL_1740 | - | 1e-149 | 84.69% (294) | membrane glycine rich protein |
| M. vanbaalenii PYR-1 | Mvan_2608 | - | 1e-127 | 73.49% (298) | protein of unknown function, zinc metallopeptidase putative |
CLUSTAL 2.0.9 multiple sequence alignment
Rv2575|M.tuberculosis_H37Rv ------------------------MTFNEGVQIDTSTTSTSGSG---GGR
Mb2605|M.bovis_AF2122/97 ------------------------MTFNEGVQIDTSTTSTSGSG---GGR
MMAR_2155|M.marinum_M ------------------------MTFNEGMQIDTSAASSSGGG---GFG
MUL_1740|M.ulcerans_Agy99 ------------------------MTFNEGMQIDTSPTSSSGGG---GFG
MAV_3451|M.avium_104 ------------------------MTFNEGMQIDTSTASSSGGG---GMG
Mflv_3788|M.gilvum_PYR-GCK MRSWTSPGTSVGRVDSTHSDGGGAMTFNEGMRIDTSTTSTSSGG-RGPGR
Mvan_2608|M.vanbaalenii_PYR-1 ------------------------MTFNEGMRIDTSTTSTSSGGGRGPGR
MSMEG_3000|M.smegmatis_MC2_155 ------------------------MTFNEGMQIDTSTTSTSGGGRRGPGR
TH_0541|M.thermoresistible__bu ------------------------------MRIDTSTTSTGGGG---GGR
MAB_2867|M.abscessus_ATCC_1997 ------------------------MTFNEGMQIDTSTTSGGGMG---RGP
::****.:* .. *
Rv2575|M.tuberculosis_H37Rv RLAIGGGLGGLLVVVVAMLLGVDPGGVLSQQP-LDTRDHVAPGFDLSQCR
Mb2605|M.bovis_AF2122/97 RLAIGGGLGGLLVVVVAMLLGVDPGGVLSQQP-LDTRDHVAPGFDLSQCR
MMAR_2155|M.marinum_M RMAIGGGIGGLLIVVVAMFLGVDPGGVLSQQP-MDDRDVVAPGFDLSQCK
MUL_1740|M.ulcerans_Agy99 RMAIGGGIGGLLIVVVAMFLGVDPGGVLSQQP-MDDRDVVAPGFDLSQCK
MAV_3451|M.avium_104 -MAVGGGGLGLIILLGALFLGVDPGRVMPQQQ-TNTGGYSAPGFDLSQCK
Mflv_3788|M.gilvum_PYR-GCK GIAVGGGLGGLLIVVVALFLGVDPSSVVPQQT--DTQGVEAPGFDLSQCR
Mvan_2608|M.vanbaalenii_PYR-1 GIAVGGGLGGLLIVVVALFLGVDPSTVLPQQPPMDTQGVEAPGFDLSQCQ
MSMEG_3000|M.smegmatis_MC2_155 GMAIGGGLGGLLIVVLALFLGVDPGQVLPQQQQMDSEGAEAGGFDLSQCR
TH_0541|M.thermoresistible__bu RIAVGGGIGGLLVVVVALLLGVDPGTVTPQQQRLDPGGAASEGFDLSQCR
MAB_2867|M.abscessus_ATCC_1997 KMAIGGGVGGLLIAVVVMLLGGDPSQVLQQQGPQQAGPAREQTQDFSHCK
:*:*** **:: : .::** **. * ** : *:*:*:
Rv2575|M.tuberculosis_H37Rv TGADANRFVQCRVVATGNSVDAVWKPLLPG-YTRPHMRLFSGQVGTG-CG
Mb2605|M.bovis_AF2122/97 TGADANRFVQCRVVATGNSVDAVWKPLLPG-YTRPHMRLFSGQVGTG-CG
MMAR_2155|M.marinum_M TGADANKYVQCRVVATGNSLDAVWTQLMPDRYTRPHLRLFSGQVSTG-CG
MUL_1740|M.ulcerans_Agy99 TGADANKYVQCRVVATGNSLDAVWTQLMPDRYTRPHLRLFSGQVSTG-CG
MAV_3451|M.avium_104 TGADANKYVQCRVVATGNSVDAVWHQLMPR-YTRPHVRLFTGRVNTG-CG
Mflv_3788|M.gilvum_PYR-GCK TGADANEIVQCRVVATGNSLDGVWAQLMPD-YTRPRVEIFTNGVQTEGCG
Mvan_2608|M.vanbaalenii_PYR-1 TGKDANEIVQCRVVATGNSLDGVWEQLMPG-YTRPQIELFTSGVETEGCG
MSMEG_3000|M.smegmatis_MC2_155 TGADANEIVQCRVVATGNSVDGVWQQLLQG-YQRPQVRLFTGQVNTG-CG
TH_0541|M.thermoresistible__bu TGADANRLAECRVVATGNSLDAVWAQLLPG-YQRPRIMLFTDAVNTG-CG
MAB_2867|M.abscessus_ATCC_1997 TGADANKSLDCRIIATGNSVDAVWTQILGPKYPRPNVKLFSNQVNTG-CG
** ***. :**::*****:*.** :: * **.: :*:. * * **
Rv2575|M.tuberculosis_H37Rv PASSEVGPFYCPVDKTAYFDTDFFQVLVTQFGSSGGPFAEEYVVAHEYGH
Mb2605|M.bovis_AF2122/97 PASSEVGPFYCPVDKTAYFDTDFFQVLVTQFGSSGGPFAEEYVVAHEYGH
MMAR_2155|M.marinum_M PASSEVGPFYCPVDQTAYFDTDFFQLLVTEFGSSGGPFAQEYVVAHEYGH
MUL_1740|M.ulcerans_Agy99 PASSEVGPFYCPVDQTAYFDTDFFQLLVTEFGSSGGPFAQEYVVAHEYGH
MAV_3451|M.avium_104 PATTAVGPFYCPVDQTAYFDTDFFQELVDRFGSSGGPFAQEYVVAHEYGH
Mflv_3788|M.gilvum_PYR-GCK PASSEVGPFYCPVDQTAYFDTGFFDVLKTQFGSSGGPFAEEYVVAHEFGH
Mvan_2608|M.vanbaalenii_PYR-1 FASSDVGPFYCPVDKTAYFDTGFFDVLKTQFGSSGGPLAEEYVVAHEFGH
MSMEG_3000|M.smegmatis_MC2_155 TATSDVGPFYCPVDKTAYFDTDFFDVLKTQFGSSGGPLAQEYVVAHEFGH
TH_0541|M.thermoresistible__bu AATSDVGPFYCPADQTAYFDTGFFDVLRDQFGSSGGPLAQEYVVAHEFGH
MAB_2867|M.abscessus_ATCC_1997 AATTEVGPFYCPADRTAYFDTSFFQVLVDQFGSSGGPLAQEYVVAHEYGH
*:: *******.*:******.**: * .*******:*:*******:**
Rv2575|M.tuberculosis_H37Rv HVQNLLGVLGRAQ-QGAQGAAGSGVRTELQADCYAGVWAYYASTVKQEST
Mb2605|M.bovis_AF2122/97 HVQNLLGVLGRAQ-QGAQGAAGSGVRTELQADCYAGVWAYYASTVKQEST
MMAR_2155|M.marinum_M HVQNLLGVLGRAQ-QGAKGAGGNGVRTELQADCYAGVWAHYASTVRQEST
MUL_1740|M.ulcerans_Agy99 HVQNLLGVLGRAQ-QGAKGAGGNGVRTELQADCYAGVWAHYASTVRQEST
MAV_3451|M.avium_104 HVQNLQGVLGRSQ-QGAQGAGGNGVRTELQADCYAGIWAHYASTVKQEST
Mflv_3788|M.gilvum_PYR-GCK HVQNLQGVLGRAQ-QDPTGPTGGGVRTELQADCYAGVWAHYAAITKQEGT
Mvan_2608|M.vanbaalenii_PYR-1 HIQNLEGVLGRAQ-QDPTGPTGGGVRTELQADCYAGIWAHYASITKQEGT
MSMEG_3000|M.smegmatis_MC2_155 HVQNLLGVLGRAQ-RDPEGATGAGVRTELQADCYAGVWAHYASITRQEST
TH_0541|M.thermoresistible__bu HVQNLQGTLGRAHGPAAQGPQGAGVRTELQADCYAGVWAHYAAITEQEDT
MAB_2867|M.abscessus_ATCC_1997 HVQNLFGVLGKNH-RCAEGQAGGGVCTELQADCYAGVWAKHASTTVQEGT
*:*** *.**: : . * * ** **********:** :*: . **.*
Rv2575|M.tuberculosis_H37Rv GVPYLEPLSDKDIQDALAAAAAVGDDRIQQQTTGRTNPETWTHGSAAQRQ
Mb2605|M.bovis_AF2122/97 GVPYLEPLSDKDIQDALAAAAAVGDDRIQQQTTGRTNPETWTHGSAAQRQ
MMAR_2155|M.marinum_M GVPFLEPLSDKDIQDALSAAASVGDDRIQQQVAGRSNPETWTHGSSAQRQ
MUL_1740|M.ulcerans_Agy99 GVPFLEPLSDKDIQDALSAAASVGDDRIQQQVAGRSNPETSTHGSSAQRQ
MAV_3451|M.avium_104 GVPYLEPLSDKDIADALSAAASVGDDRIQKQATGRVNPESWTHGSSEQRQ
Mflv_3788|M.gilvum_PYR-GCK DVPFLEPLTDQQIADALSAAAAVGDDRIQETATGRVNPESWTHGSSEQRQ
Mvan_2608|M.vanbaalenii_PYR-1 DVPFLEPLSDKDIADALSAASAVGDDRIQEAATGRVSPESWTHGSSTQRQ
MSMEG_3000|M.smegmatis_MC2_155 GVPFLEPLSDKDIADALSAAASVGDDRIQQSATGRVNPEAWTHGSSAQRQ
TH_0541|M.thermoresistible__bu GVPFLEPLSDQDIADALSAAAAVGDDRIQQAATGRVSPESWTHGSSAQRQ
MAB_2867|M.abscessus_ATCC_1997 GVPFLKPLTEQDIRDALSAASSVGDDRIQKRATGRVNPEAWSHGSSEQRQ
.**:*:**::::* ***:**::*******: .:** .**: :***: ***
Rv2575|M.tuberculosis_H37Rv KWFTVGYQTGDPNICDTFSAADLG
Mb2605|M.bovis_AF2122/97 KWFTVGYQTGDPNICDTFSAADLG
MMAR_2155|M.marinum_M KWFTVGYQTGDPNKCDTFSATNLG
MUL_1740|M.ulcerans_Agy99 KWFTVGYQTSDPNKCDTFSATNLG
MAV_3451|M.avium_104 KWFTIGYQTGDPKQCDTFSAPDLG
Mflv_3788|M.gilvum_PYR-GCK KWFTTGYQTGDPARCDTFATNNLG
Mvan_2608|M.vanbaalenii_PYR-1 KWFTTGYQTGDPARCDTFATNNLG
MSMEG_3000|M.smegmatis_MC2_155 KWFTEGYRTGDPNKCDTFATNDLG
TH_0541|M.thermoresistible__bu KWFTVGYQTGDPQRCDTFATDDLG
MAB_2867|M.abscessus_ATCC_1997 RWFTQGYNTGDFRTCDTFNAQSLN
:*** **.*.* **** : .*.