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M. vanbaalenii PYR-1 Mvan_2608 (-)

annotation: protein of unknown function, zinc metallopeptidase putative
coordinates: 2757421 - 2758317
length: 298

TFNEGMRIDTSTTSTSSGGGRGPGRGIAVGGGLGGLLIVVVALFLGVDPSTVLPQQPPMDTQGVEAPGFD
LSQCQTGKDANEIVQCRVVATGNSLDGVWEQLMPGYTRPQIELFTSGVETEGCGFASSDVGPFYCPVDKT
AYFDTGFFDVLKTQFGSSGGPLAEEYVVAHEFGHHIQNLEGVLGRAQQDPTGPTGGGVRTELQADCYAGI
WAHYASITKQEGTDVPFLEPLSDKDIADALSAASAVGDDRIQEAATGRVSPESWTHGSSTQRQKWFTTGY
QTGDPARCDTFATNNLG*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. vanbaalenii PYR-1Mvan_2608--100% (298)protein of unknown function, zinc metallopeptidase putative

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2605-1e-12773.49% (298) hypothetical protein Mb2605
M. gilvum PYR-GCKMflv_3788-1e-16089.93% (298) protein of unknown function, zinc metallopeptidase putative
M. tuberculosis H37RvRv2575-1e-12773.49% (298) hypothetical protein Rv2575
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2867-1e-10963.76% (298) hypothetical protein MAB_2867
M. marinum MMMAR_2155-1e-12673.24% (299) membrane glycine rich protein
M. avium 104MAV_3451-1e-12472.48% (298) metallopeptidase, zinc binding
M. smegmatis MC2 155MSMEG_3000-1e-14782.21% (298) metallopeptidase, zinc binding
M. thermoresistible (build 8)TH_0541-1e-13277.13% (293) POSSIBLE CONSERVED MEMBRANE GLYCINE RICH PROTEIN
M. ulcerans Agy99MUL_1740-1e-12472.91% (299) membrane glycine rich protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb2605|M.bovis_AF2122/97            ------------------------MTFNEGVQIDTSTTSTSGSG---GGR
Rv2575|M.tuberculosis_H37Rv         ------------------------MTFNEGVQIDTSTTSTSGSG---GGR
MMAR_2155|M.marinum_M               ------------------------MTFNEGMQIDTSAASSSGGG---GFG
MUL_1740|M.ulcerans_Agy99           ------------------------MTFNEGMQIDTSPTSSSGGG---GFG
MAV_3451|M.avium_104                ------------------------MTFNEGMQIDTSTASSSGGG---GMG
Mvan_2608|M.vanbaalenii_PYR-1       ------------------------MTFNEGMRIDTSTTSTSSGGGRGPGR
Mflv_3788|M.gilvum_PYR-GCK          MRSWTSPGTSVGRVDSTHSDGGGAMTFNEGMRIDTSTTSTSSGG-RGPGR
MSMEG_3000|M.smegmatis_MC2_155      ------------------------MTFNEGMQIDTSTTSTSGGGRRGPGR
TH_0541|M.thermoresistible__bu      ------------------------------MRIDTSTTSTGGGG---GGR
MAB_2867|M.abscessus_ATCC_1997      ------------------------MTFNEGMQIDTSTTSGGGMG---RGP
                                                                  ::****.:* .. *      

Mb2605|M.bovis_AF2122/97            RLAIGGGLGGLLVVVVAMLLGVDPGGVLSQQP-LDTRDHVAPGFDLSQCR
Rv2575|M.tuberculosis_H37Rv         RLAIGGGLGGLLVVVVAMLLGVDPGGVLSQQP-LDTRDHVAPGFDLSQCR
MMAR_2155|M.marinum_M               RMAIGGGIGGLLIVVVAMFLGVDPGGVLSQQP-MDDRDVVAPGFDLSQCK
MUL_1740|M.ulcerans_Agy99           RMAIGGGIGGLLIVVVAMFLGVDPGGVLSQQP-MDDRDVVAPGFDLSQCK
MAV_3451|M.avium_104                -MAVGGGGLGLIILLGALFLGVDPGRVMPQQQ-TNTGGYSAPGFDLSQCK
Mvan_2608|M.vanbaalenii_PYR-1       GIAVGGGLGGLLIVVVALFLGVDPSTVLPQQPPMDTQGVEAPGFDLSQCQ
Mflv_3788|M.gilvum_PYR-GCK          GIAVGGGLGGLLIVVVALFLGVDPSSVVPQQT--DTQGVEAPGFDLSQCR
MSMEG_3000|M.smegmatis_MC2_155      GMAIGGGLGGLLIVVLALFLGVDPGQVLPQQQQMDSEGAEAGGFDLSQCR
TH_0541|M.thermoresistible__bu      RIAVGGGIGGLLVVVVALLLGVDPGTVTPQQQRLDPGGAASEGFDLSQCR
MAB_2867|M.abscessus_ATCC_1997      KMAIGGGVGGLLIAVVVMLLGGDPSQVLQQQGPQQAGPAREQTQDFSHCK
                                     :*:***  **:: : .::** **. *  **   :         *:*:*:

Mb2605|M.bovis_AF2122/97            TGADANRFVQCRVVATGNSVDAVWKPLLPG-YTRPHMRLFSGQVGTG-CG
Rv2575|M.tuberculosis_H37Rv         TGADANRFVQCRVVATGNSVDAVWKPLLPG-YTRPHMRLFSGQVGTG-CG
MMAR_2155|M.marinum_M               TGADANKYVQCRVVATGNSLDAVWTQLMPDRYTRPHLRLFSGQVSTG-CG
MUL_1740|M.ulcerans_Agy99           TGADANKYVQCRVVATGNSLDAVWTQLMPDRYTRPHLRLFSGQVSTG-CG
MAV_3451|M.avium_104                TGADANKYVQCRVVATGNSVDAVWHQLMPR-YTRPHVRLFTGRVNTG-CG
Mvan_2608|M.vanbaalenii_PYR-1       TGKDANEIVQCRVVATGNSLDGVWEQLMPG-YTRPQIELFTSGVETEGCG
Mflv_3788|M.gilvum_PYR-GCK          TGADANEIVQCRVVATGNSLDGVWAQLMPD-YTRPRVEIFTNGVQTEGCG
MSMEG_3000|M.smegmatis_MC2_155      TGADANEIVQCRVVATGNSVDGVWQQLLQG-YQRPQVRLFTGQVNTG-CG
TH_0541|M.thermoresistible__bu      TGADANRLAECRVVATGNSLDAVWAQLLPG-YQRPRIMLFTDAVNTG-CG
MAB_2867|M.abscessus_ATCC_1997      TGADANKSLDCRIIATGNSVDAVWTQILGPKYPRPNVKLFSNQVNTG-CG
                                    ** ***.  :**::*****:*.**  ::   * **.: :*:. * *  **

Mb2605|M.bovis_AF2122/97            PASSEVGPFYCPVDKTAYFDTDFFQVLVTQFGSSGGPFAEEYVVAHEYGH
Rv2575|M.tuberculosis_H37Rv         PASSEVGPFYCPVDKTAYFDTDFFQVLVTQFGSSGGPFAEEYVVAHEYGH
MMAR_2155|M.marinum_M               PASSEVGPFYCPVDQTAYFDTDFFQLLVTEFGSSGGPFAQEYVVAHEYGH
MUL_1740|M.ulcerans_Agy99           PASSEVGPFYCPVDQTAYFDTDFFQLLVTEFGSSGGPFAQEYVVAHEYGH
MAV_3451|M.avium_104                PATTAVGPFYCPVDQTAYFDTDFFQELVDRFGSSGGPFAQEYVVAHEYGH
Mvan_2608|M.vanbaalenii_PYR-1       FASSDVGPFYCPVDKTAYFDTGFFDVLKTQFGSSGGPLAEEYVVAHEFGH
Mflv_3788|M.gilvum_PYR-GCK          PASSEVGPFYCPVDQTAYFDTGFFDVLKTQFGSSGGPFAEEYVVAHEFGH
MSMEG_3000|M.smegmatis_MC2_155      TATSDVGPFYCPVDKTAYFDTDFFDVLKTQFGSSGGPLAQEYVVAHEFGH
TH_0541|M.thermoresistible__bu      AATSDVGPFYCPADQTAYFDTGFFDVLRDQFGSSGGPLAQEYVVAHEFGH
MAB_2867|M.abscessus_ATCC_1997      AATTEVGPFYCPADRTAYFDTSFFQVLVDQFGSSGGPLAQEYVVAHEYGH
                                     *:: *******.*:******.**: *  .*******:*:*******:**

Mb2605|M.bovis_AF2122/97            HVQNLLGVLGRAQ-QGAQGAAGSGVRTELQADCYAGVWAYYASTVKQEST
Rv2575|M.tuberculosis_H37Rv         HVQNLLGVLGRAQ-QGAQGAAGSGVRTELQADCYAGVWAYYASTVKQEST
MMAR_2155|M.marinum_M               HVQNLLGVLGRAQ-QGAKGAGGNGVRTELQADCYAGVWAHYASTVRQEST
MUL_1740|M.ulcerans_Agy99           HVQNLLGVLGRAQ-QGAKGAGGNGVRTELQADCYAGVWAHYASTVRQEST
MAV_3451|M.avium_104                HVQNLQGVLGRSQ-QGAQGAGGNGVRTELQADCYAGIWAHYASTVKQEST
Mvan_2608|M.vanbaalenii_PYR-1       HIQNLEGVLGRAQ-QDPTGPTGGGVRTELQADCYAGIWAHYASITKQEGT
Mflv_3788|M.gilvum_PYR-GCK          HVQNLQGVLGRAQ-QDPTGPTGGGVRTELQADCYAGVWAHYAAITKQEGT
MSMEG_3000|M.smegmatis_MC2_155      HVQNLLGVLGRAQ-RDPEGATGAGVRTELQADCYAGVWAHYASITRQEST
TH_0541|M.thermoresistible__bu      HVQNLQGTLGRAHGPAAQGPQGAGVRTELQADCYAGVWAHYAAITEQEDT
MAB_2867|M.abscessus_ATCC_1997      HVQNLFGVLGKNH-RCAEGQAGGGVCTELQADCYAGVWAKHASTTVQEGT
                                    *:*** *.**: :   . *  * ** **********:** :*: . **.*

Mb2605|M.bovis_AF2122/97            GVPYLEPLSDKDIQDALAAAAAVGDDRIQQQTTGRTNPETWTHGSAAQRQ
Rv2575|M.tuberculosis_H37Rv         GVPYLEPLSDKDIQDALAAAAAVGDDRIQQQTTGRTNPETWTHGSAAQRQ
MMAR_2155|M.marinum_M               GVPFLEPLSDKDIQDALSAAASVGDDRIQQQVAGRSNPETWTHGSSAQRQ
MUL_1740|M.ulcerans_Agy99           GVPFLEPLSDKDIQDALSAAASVGDDRIQQQVAGRSNPETSTHGSSAQRQ
MAV_3451|M.avium_104                GVPYLEPLSDKDIADALSAAASVGDDRIQKQATGRVNPESWTHGSSEQRQ
Mvan_2608|M.vanbaalenii_PYR-1       DVPFLEPLSDKDIADALSAASAVGDDRIQEAATGRVSPESWTHGSSTQRQ
Mflv_3788|M.gilvum_PYR-GCK          DVPFLEPLTDQQIADALSAAAAVGDDRIQETATGRVNPESWTHGSSEQRQ
MSMEG_3000|M.smegmatis_MC2_155      GVPFLEPLSDKDIADALSAAASVGDDRIQQSATGRVNPEAWTHGSSAQRQ
TH_0541|M.thermoresistible__bu      GVPFLEPLSDQDIADALSAAAAVGDDRIQQAATGRVSPESWTHGSSAQRQ
MAB_2867|M.abscessus_ATCC_1997      GVPFLKPLTEQDIRDALSAASSVGDDRIQKRATGRVNPEAWSHGSSEQRQ
                                    .**:*:**::::* ***:**::*******: .:** .**: :***: ***

Mb2605|M.bovis_AF2122/97            KWFTVGYQTGDPNICDTFSAADLG
Rv2575|M.tuberculosis_H37Rv         KWFTVGYQTGDPNICDTFSAADLG
MMAR_2155|M.marinum_M               KWFTVGYQTGDPNKCDTFSATNLG
MUL_1740|M.ulcerans_Agy99           KWFTVGYQTSDPNKCDTFSATNLG
MAV_3451|M.avium_104                KWFTIGYQTGDPKQCDTFSAPDLG
Mvan_2608|M.vanbaalenii_PYR-1       KWFTTGYQTGDPARCDTFATNNLG
Mflv_3788|M.gilvum_PYR-GCK          KWFTTGYQTGDPARCDTFATNNLG
MSMEG_3000|M.smegmatis_MC2_155      KWFTEGYRTGDPNKCDTFATNDLG
TH_0541|M.thermoresistible__bu      KWFTVGYQTGDPQRCDTFATDDLG
MAB_2867|M.abscessus_ATCC_1997      RWFTQGYNTGDFRTCDTFNAQSLN
                                    :*** **.*.*   **** : .*.