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MAPSASAATNGYDVDRLLAGYRTARAQETLFDLRDGPGAGYDEFVDDDGNVRPTWTELADAVAERGKAGL DRLRSVVHSLIDHDGITYTAIDAHRDALTGDHDLEPGPWRLDPLPLVISAADWEVLEAGLVQRSRLLDAI LADLYGPRSMLTEGVLPPEMLFAHPGYVRAANGIQMPGRHQLFMHACDLSRLPDGTFQVNADWTQAPSGS GYAMADRRVVAHAVPDLYEELAPRPTTPFAQALRLALIDAAPDVAQDPVVVVLSPGIYSETAFDQAYLAT LLGFPLVESADLVVRDGKLWMRSLGTLKRVDVVLRRVDAHYADPLDLRADSRLGVVGLVEAQHRGTVTVV NTLGSGILENPGLLRFLPQLSERLLDESPLLHTAPVYWGGIASERSHLLANVSSLLIKSTVSGETLVGPT LSSAQLADLAVRIEAMPWQWVGQELPQFSSAPTNHAGVLSSAGVGMRLFTVAQRSGYAPMIGGLGYVLAP GPAAYTLKTVAAKDIWVRPTERAHAEVITVPVLAPPAKTGAGTWAVSSPRVLSDLFWMGRYGERAENMAR LLIVTRERYHVFRHQQDTDESECVPVLMAALGKITGYDTATGAGSAYDRADMIAVAPSTLWSLTVDPDRP GSLVQSVEGLALAAQAVRDQLSNDTWMVLANVERAVEHKSDPPQSLAEADAVLASAQAETLAGMLTLSGV AGESMVHDVGWTMMDIGKRIERGLWLTALLQATLSTVRHPAAEQAIIEATLVACESSVIYRRRTVGKFSV AAVTELMLFDAQNPRSLVYQLERLRADLKDLPGSSGSSRPERMVDEMNTRLRRSHPEELEEVSADGLRAE LAELLAGIHASLRDVADVLTATQLALPGGMQPLWGPDQRRVMPA
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. tuberculosis H37Rv | Rv2567 | - | - | 100% (884) | CONSERVED HYPOTHETICAL ALANINE AND LEUCINE RICH PROTEIN |
M. tuberculosis H37Rv | Rv2411c | - | 5e-61 | 32.80% (503) | hypothetical protein Rv2411c |
M. tuberculosis H37Rv | Rv2410c | - | 1e-13 | 24.53% (318) | hypothetical protein Rv2410c |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2597 | - | 0.0 | 99.89% (884) | hypothetical protein Mb2597 |
M. gilvum PYR-GCK | Mflv_3770 | - | 0.0 | 66.67% (885) | hypothetical protein Mflv_3770 |
M. leprae Br4923 | MLBr_02679 | - | 0.0 | 75.20% (883) | hypothetical protein MLBr_02679 |
M. abscessus ATCC 19977 | MAB_2858c | - | 0.0 | 62.10% (897) | hypothetical protein MAB_2858c |
M. marinum M | MMAR_2164 | - | 0.0 | 81.66% (894) | hypothetical protein MMAR_2164 |
M. avium 104 | MAV_3438 | - | 0.0 | 80.16% (882) | hypothetical protein MAV_3438 |
M. smegmatis MC2 155 | MSMEG_3017 | - | 0.0 | 67.50% (883) | hypothetical protein MSMEG_3017 |
M. thermoresistible (build 8) | - | - | - | - | - |
M. ulcerans Agy99 | MUL_1748 | - | 0.0 | 81.01% (895) | hypothetical protein MUL_1748 |
M. vanbaalenii PYR-1 | Mvan_2629 | - | 0.0 | 68.40% (886) | hypothetical protein Mvan_2629 |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_3770|M.gilvum_PYR-GCK ------MAVPATPPTPRLGAGRT----------------DVDNPLEPYGS Mvan_2629|M.vanbaalenii_PYR-1 ------MAHPAPSPTPAPGAGST----------------DVDNPLVPYGT MSMEG_3017|M.smegmatis_MC2_155 ------MVLRANGSQPTSTAGAAGDLGAGSDVSGAPGIRDVDGVLEKYRR Rv2567|M.tuberculosis_H37Rv -------------MAPSASAATNG--------------YDVDRLLAGYRT Mb2597|M.bovis_AF2122/97 -------------MAPSASAATNG--------------YDVDRLLAGYRT MMAR_2164|M.marinum_M ------------MSRPAAVAAAEP--------------YDVDRLLAGYRT MUL_1748|M.ulcerans_Agy99 --------MVLGMSSPAAVAAAEP--------------YDVDRLLAGYRT MAV_3438|M.avium_104 ---MAFADRTFGTGGPSAAAGGS---------------YDADRLLAGYRT MLBr_02679|M.leprae_Br4923 MIRYMVSTEMALSNSASSSARFNH--------------SDADRLLDGYRA MAB_2858c|M.abscessus_ATCC_199 ------MAAPASGAPVGPGFAVGD-----------------NPLIAQYAS : : * Mflv_3770|M.gilvum_PYR-GCK MRAQPSLFDVASA--FGGLAGYDEFVDTAGDVRPAWQELADCVRDRGRGG Mvan_2629|M.vanbaalenii_PYR-1 MRAQQVLFEQPQF--GGPTTGYDEFVDAAGNVRPAWQELADCVRDRGRDG MSMEG_3017|M.smegmatis_MC2_155 TRLQRALFDVRGS--QAGTA-YDEFVDTAGEVRPAWRELAECVSERGRSG Rv2567|M.tuberculosis_H37Rv ARAQETLFDLR----DGPGAGYDEFVDDDGNVRPTWTELADAVAERGKAG Mb2597|M.bovis_AF2122/97 ARAQETLFDLR----DGPGAGYDEFVDDDGNVRPTWTELADAVAERGKAG MMAR_2164|M.marinum_M ARAQEALFDVR----DSPGIGYDEFVDADGNVRPAWTELADAVAERGRTG MUL_1748|M.ulcerans_Agy99 ARAQEALFDVR----DSPGIGYDEFVDADGNVRPAWTELADAVAERGRTG MAV_3438|M.avium_104 ARAQQALFDLR----QGPASGYDEFVGPDGKVRPAWTELADAIGERGRAG MLBr_02679|M.leprae_Br4923 ARAQKVLFDLHSAGTAGPGIGYDEFVDDSGYVRPSWTELADAIGGRGRAG MAB_2858c|M.abscessus_ATCC_199 ARAQGALFEVGR---RGDQAGYDEFLAPDGSVRPAWTDLADAIAQRGRPG * * **: . ****: * ***:* :**:.: **: * Mflv_3770|M.gilvum_PYR-GCK LDRLRAVVRDLVDNDGITYVQTDR--------EGEPVAGPWRLDALPLVI Mvan_2629|M.vanbaalenii_PYR-1 LDRLRAVVRGLVDNDGITYIQTD---------DGDAVPGPWHLDALPLVI MSMEG_3017|M.smegmatis_MC2_155 LDRLREQVNALVDADGITYIQVDRHGEIVIDREGAAMPGPWHLDALPMVI Rv2567|M.tuberculosis_H37Rv LDRLRSVVHSLIDHDGITYTAIDAHRDAL-TGDHDLEPGPWRLDPLPLVI Mb2597|M.bovis_AF2122/97 LDRLRSVVHSLIDHDGITYTAIDAHRDAL-TGDHDLEPGPWRLDPLPLVI MMAR_2164|M.marinum_M LDRLRSVVHSLIDHDGITYTGVDSGRED--HGVHGLEPGPWRLDTLPLVV MUL_1748|M.ulcerans_Agy99 LDRLRSVVHSLIDHDGITYTGVDSGRED--HGVHGLEPGPWRLDTLPLVV MAV_3438|M.avium_104 LDRLRSVVRGLIDHDGITYTDVEP-------GGRGQEPRPWQLDTLPIVL MLBr_02679|M.leprae_Br4923 LHQLRSVMHRLIYNDGITYTGIDPG--AL-TNDHGVVPGLWRLDSLPLLV MAB_2858c|M.abscessus_ATCC_199 LDRLLDRVHTLVDSDGITYMDPRRAPGSVSGPDAPAHPVPWRLDGLPLLL *.:* :. *: ***** . *:** **::: Mflv_3770|M.gilvum_PYR-GCK SASDWDHLEAGLVQRSRLLDAVLTDVYGERRVVTGGVLPPELLFSHPGYL Mvan_2629|M.vanbaalenii_PYR-1 SAADWDRLEAGLVQRSRLLDAVLADLYGERRSITGGVLPPQLLFAHPGYV MSMEG_3017|M.smegmatis_MC2_155 SAEEWDVLEAGLVQRSRLLDAVLADLYGERRSITSGVLPAQLLFSHPGYL Rv2567|M.tuberculosis_H37Rv SAADWEVLEAGLVQRSRLLDAILADLYGPRSMLTEGVLPPEMLFAHPGYV Mb2597|M.bovis_AF2122/97 SAADWEVLEAGLVQRSRLLDAILADLYGPRSMLTEGVLPPEMLFAHPGYV MMAR_2164|M.marinum_M SAQDWEVLEAGLVQRSRLLDAVLADLYGPRRLLTEGLLPSELVFGHPAYV MUL_1748|M.ulcerans_Agy99 SARDWEVLEAGLVQRSRLLDAVLADLYGPRRLLTEGLLPSELVFGHPAYV MAV_3438|M.avium_104 SAADWEPLEAGLLQRSRVLDAVLADLYGPRSLLTEGVLPPELLFGHPGYL MLBr_02679|M.leprae_Br4923 SATDWEVLEAGLIQRSRLLDAVLTDLYGPRRLLTDGVLPPELLFGHPGYV MAB_2858c|M.abscessus_ATCC_199 DPADWNVLEVGLTQRATLLDAVLSDLYGAQELISSGALPPQLLFAHPGYV .. :*: **.** **: :***:*:*:** : :: * **.:::*.**.*: Mflv_3770|M.gilvum_PYR-GCK RAANGIEIPGRHQLFLHGCDISRNGTGDFVVNADYTQAPSGAGYALADRR Mvan_2629|M.vanbaalenii_PYR-1 RAARGIEVPGRHQLFLHGCDVSRGSSGDFVVNADWTQAPSGAGYALADRR MSMEG_3017|M.smegmatis_MC2_155 RAAHGITVPGRHQLFLHGCDISRGDDGAFVVNADWTQAPSGAGYALADRR Rv2567|M.tuberculosis_H37Rv RAANGIQMPGRHQLFMHACDLSRLPDGTFQVNADWTQAPSGSGYAMADRR Mb2597|M.bovis_AF2122/97 RAANGIQMPGRHQLFMHACDLSRLPDGTFQVNADWTQAPSGSGYAMADRR MMAR_2164|M.marinum_M RGANGIEVPGHHQLFLHGCDISRIPDGSYQVNADWTQAPSGAGYALADRR MUL_1748|M.ulcerans_Agy99 RGANGIEVPGHHQLFLHGCDISRIPDGSYQVNADWTQAPSGAGYALADRR MAV_3438|M.avium_104 RAANGIEIPGRHQLFMHACDVSRRPDGGFAVNADRTQAPSGAGYALADRR MLBr_02679|M.leprae_Br4923 RTDHGIEVPGHHQLFMHGCDLSRLPDGGFQINADWTQAPSGAGYALADRR MAB_2858c|M.abscessus_ATCC_199 RAAHGMALPGRHQLFLLGCDISRTATGDFRVNADWTQAPSGAGYAMADRR * .*: :**:****: .**:** * : :*** ******:***:**** Mflv_3770|M.gilvum_PYR-GCK VVAHAIPDLYEQIGPRQSSPWAQALRLALVDAAPDAVDEPMVVVLSPGIH Mvan_2629|M.vanbaalenii_PYR-1 VIAHAIPELYEQIGPQPVSPWAQALRLALVDAAPESAEEPMVVVLSPGIH MSMEG_3017|M.smegmatis_MC2_155 VIAHAVSELYERIAPRPVSPWAQALRLALIDVAPESAEEPVVVVLSPGIH Rv2567|M.tuberculosis_H37Rv VVAHAVPDLYEELAPRPTTPFAQALRLALIDAAPDVAQDPVVVVLSPGIY Mb2597|M.bovis_AF2122/97 VVAHAVPDLYEELAPRPTTPFAQALRLALIDAAPDVAQDPVVVVLSPGIY MMAR_2164|M.marinum_M VVAHAIPDLYENIAPRPTTPFAQALRLALIDAAPDVAQDPVVVVLSPGIY MUL_1748|M.ulcerans_Agy99 VVAHAIPDLYENIAPRPTTPFAQALRLALIDAAPDVAQDPVVVVLSPGIY MAV_3438|M.avium_104 VVAHAIPDLYERIAPRPTTPFAQALRLALIDAAPDVAQDPVVVVLSPGIY MLBr_02679|M.leprae_Br4923 VVAQALPDLYETIGPRPTTPFAQALRLALIDAAPEVAQDPVVVVLSPGIY MAB_2858c|M.abscessus_ATCC_199 VVAHAAPDLYEKVAPRPTSSFAQTLRLALIDVAPESVEDPTIVVLSPGIH *:*:* .:*** :.*: :.:**:*****:*.**: .::* :*******: Mflv_3770|M.gilvum_PYR-GCK SETAFDQAYLASVLGLPLVESADLVVRDGMLWMRSMGTLKRVDVVLRRVD Mvan_2629|M.vanbaalenii_PYR-1 SETAFDQAYLASVLGLPLVESADLVVRDGKLWMRSMGTLKRVDVVLRRVD MSMEG_3017|M.smegmatis_MC2_155 SETAFDQAYLAGVLGFPLVESADLVVRDGKLWMRSLGTLKRVDVVLRRVD Rv2567|M.tuberculosis_H37Rv SETAFDQAYLATLLGFPLVESADLVVRDGKLWMRSLGTLKRVDVVLRRVD Mb2597|M.bovis_AF2122/97 SETAFDQAYLATLLGFPLVESADLVVRDGKLWMRSLGTLKRVDVVLRRVD MMAR_2164|M.marinum_M SETAFDQAYLATLLGFPLVESADLVVRDGKLWMRSLGTLKRVDVVLRRVD MUL_1748|M.ulcerans_Agy99 SETAFDQAYLATLLGFPLVESADLVVRDGKLWMRSLGTLKRVDVVLRRVD MAV_3438|M.avium_104 SETAFDQAYLATLLGFPLVESADLVVRDGMVWMRSLGTLKRVDVVLRRVD MLBr_02679|M.leprae_Br4923 SETAFDQAYLATLLGFQLVESSDLVVCDGKVWMRSLGTLKRVDVVLRRVD MAB_2858c|M.abscessus_ATCC_199 SETSFDQAYLASVLGFPLVESADLVVRDGKLWMRSLGTLRRVDVVLRRVD ***:******* :**: ****:**** ** :****:***:********** Mflv_3770|M.gilvum_PYR-GCK ADYADPLDLRPASRLGVVGLVEVLRRGAVTVVNSLGSGVLESPGLLRFLP Mvan_2629|M.vanbaalenii_PYR-1 ADYADPLDLRPDSRLGVVGLVEVLRRGAVTVVNTLGSGVLESPGLLRFLP MSMEG_3017|M.smegmatis_MC2_155 ADYVDPLDLRPDSRLGVVGLVEVLRRGAVTVVNSLGSGVLESPGVTRFLP Rv2567|M.tuberculosis_H37Rv AHYADPLDLRADSRLGVVGLVEAQHRGTVTVVNTLGSGILENPGLLRFLP Mb2597|M.bovis_AF2122/97 AHYADPLDLRADSRLGVVGLVEAQHRGTVTVVNTLGSGILENPGLLRFLP MMAR_2164|M.marinum_M AAYADPLDLRADSRLGVVGLVEAQHRGAVTVVNTLGSGILESPGLMRFLP MUL_1748|M.ulcerans_Agy99 AAYADPLDLRADSRLGVVGLVEAQHRGAVTVVNTLGSGILESPGLMRFLP MAV_3438|M.avium_104 AEYCDPLDLRADSRLGVAGLVEAQHRGTVTVVNTLGSGILENPGLQRFLP MLBr_02679|M.leprae_Br4923 ADYMDPLDLRADSLLGVAGLVEAQHRGTVTVVNTLGSGILESAGLLRFLP MAB_2858c|M.abscessus_ATCC_199 ADYSDPLDLRADSQLGVVGLVEVLRRGAVTVVNSLGSGVLENPGLARFLP * * ******. * ***.****. :**:*****:****:**..*: **** Mflv_3770|M.gilvum_PYR-GCK EMAEHLLGETPLLPTPHLYWGGIDIERSHLVSNLGSLVIRPVTGGEPIVG Mvan_2629|M.vanbaalenii_PYR-1 QLAETLLGETPLLATAPLYWGGSDIERSHLLANLSSLLIRPVNGGEAIVG MSMEG_3017|M.smegmatis_MC2_155 QLAQLLLDETPQLDTAPLYWGGIDIERSHLLTRLDSLLIRPVCGGKPIVG Rv2567|M.tuberculosis_H37Rv QLSERLLDESPLLHTAPVYWGGIASERSHLLANVSSLLIKSTVSGETLVG Mb2597|M.bovis_AF2122/97 QLSERLLDESPLLHTAPVYWGGIASERSHLLANVSSLLIKSTVSGETLVG MMAR_2164|M.marinum_M GLAERLLGEEPMLQSAPMYWGGIATERSHLLANLSSLLIKSTVGGNTRVG MUL_1748|M.ulcerans_Agy99 GLAERLLGEEPMLQSAPMYWGGIATERSHLLANLSSLLIKSTVGGKTRVG MAV_3438|M.avium_104 AMARHLLSETLLLPSAPVYWGGIDTERSHLLANLASLLVKSTVGGKTLVG MLBr_02679|M.leprae_Br4923 QLSERLLGETLLLPSAPVYWAGIDSERLHLLTNLSSLLIKSTVGGKTIVG MAB_2858c|M.abscessus_ATCC_199 DLSRRLLDEPLALSGGQSWWGGIDTERSHLLANLASLLVKSTAEEEVYTG ::. **.* * :*.* ** **::.: **:::.. : .* Mflv_3770|M.gilvum_PYR-GCK ATLSAARREELAARITATPWQWVGQEPPEFSSAPSDFLPGGLSSSSVGMR Mvan_2629|M.vanbaalenii_PYR-1 PQLSRAQQESLAARITATPWQWVGQELPQFSSAPADHLPGRLSSSSVGMR MSMEG_3017|M.smegmatis_MC2_155 PELSTAQREELAARIEATPWQWVGQELPQYSTAPVDFRSSGLSSAGVGMR Rv2567|M.tuberculosis_H37Rv PTLSSAQLADLAVRIEAMPWQWVGQELPQFSSAPTNH-AGVLSSAGVGMR Mb2597|M.bovis_AF2122/97 PTLSSAQLADLAVRIEAMPWQWVGQELPQFSSAPTNH-AGVLSSAGVGMR MMAR_2164|M.marinum_M PTLSSAQLAELAARIEAMPWQWVGQELPAFSSAPTDH-AGVLSSAGVGMR MUL_1748|M.ulcerans_Agy99 PTLSSAQLAELAARIEAMPWQWVGQELPAFSSAPTDH-AGVLSSAGVGMR MAV_3438|M.avium_104 PALSSRQLAQLAARIETAPWQWIGQELPQFSSAPTDH-AGVLSSAGVGIR MLBr_02679|M.leprae_Br4923 PSLSSGQLTEMAARIAAKPWQWVGQELPQFSTAPTDH-DGVLSPASIGMR MAB_2858c|M.abscessus_ATCC_199 PLESAQTLETLRARIEAQPWRWVGQELPELSVAPTYLRSGALTAAPVGMR . * : .** : **:*:*** * * ** . *:.: :*:* Mflv_3770|M.gilvum_PYR-GCK LFTVSQRSGYAPMIGGLGYLLAPGADAYRLKSVAAKDVWVRTATRVTAEA Mvan_2629|M.vanbaalenii_PYR-1 LFTVSQRSGYAPMIGGLGYLAAPGADGYRLKSVAAKDIWVRPPSRVTVEK MSMEG_3017|M.smegmatis_MC2_155 LFTVAQRSGYAPMVGGLGYLMAPGNAAFRTNTVAAKDIWVRTPDRVTAER Rv2567|M.tuberculosis_H37Rv LFTVAQRSGYAPMIGGLGYVLAPGPAAYTLKTVAAKDIWVRPTERAHAEV Mb2597|M.bovis_AF2122/97 LFTVAQRSGYAPMIGGLGYVLAPGPAAYTLKTVAAKDIWVRPTERAHAEV MMAR_2164|M.marinum_M LFTVAQRSGYSPMIGGLGYVLAPGPAAYTLRSVAAKDIWVRPTERAIVET MUL_1748|M.ulcerans_Agy99 LFTVAQRSGYSPMIGGLGYVLAPGPAAYTLRSVAAKDIWVRPTERAIVET MAV_3438|M.avium_104 LFTVAQRGGYAPMIGGIGYLLAAGPAAYTLKSVAAKDVWVRPTERARAEA MLBr_02679|M.leprae_Br4923 VFTVAQRSGYAPMIGGLGYALASGIDAYSLKKVAAKDIWVLPTERARTEA MAB_2858c|M.abscessus_ATCC_199 LFTVAQRGGYAPMIGGLGYVAASGYSGSTLNSFAAKDLWVQQPDRDQTER :***:**.**:**:**:** *.* . ...****:** . * .* Mflv_3770|M.gilvum_PYR-GCK VP-LPALAT---------------SSPTQEVSSPRVLSDLFWIGRYAERA Mvan_2629|M.vanbaalenii_PYR-1 TPALPTLAT---------------SSPTQEVSSPRVLSDLFWIGRYAERA MSMEG_3017|M.smegmatis_MC2_155 IQAPVELATP-----------ETRPSPTRVVSSPRVLADLFWLGRYAERA Rv2567|M.tuberculosis_H37Rv ITVPVLAP------------PAKTGAGTWAVSSPRVLSDLFWMGRYGERA Mb2597|M.bovis_AF2122/97 ITVPVLAP------------PAKTGAGTWAVSSPRVLSDLFWMGRYGERA MMAR_2164|M.marinum_M VAAPVTGPIVQPILEPSALVPIKTGAGTLGVSSPRVLSDLFWMGRYGERA MUL_1748|M.ulcerans_Agy99 VAAPVTGPIVQPILEPSALVPIKTGAGTLGVSSPRVLSDLFWMGRYGERA MAV_3438|M.avium_104 VGVPAVEP------------PAKTAAGTWAVSFPRVLSELFWIGRYGERA MLBr_02679|M.leprae_Br4923 ITHSLLES------------PPMTGTGTLGVSSPRVLSDLFWMGRYGERA MAB_2858c|M.abscessus_ATCC_199 ALTVAPLDLP-----------GGRSAGSDAVSSPRVLSDLFWLGRYGERA : : ** ****::***:***.*** Mflv_3770|M.gilvum_PYR-GCK EHTARLLTVTRERYHEYRYRRTMDGSECVPVLLTALGEITG----TDTGA Mvan_2629|M.vanbaalenii_PYR-1 EHMARLLTVTRERYHEYRYRRTMDGSECVPVLLTALGEITG----TDTGA MSMEG_3017|M.smegmatis_MC2_155 ESTARLLNVTRERYHEYRYRQAFEESRCVPVLLGALGSIKG----TDTGA Rv2567|M.tuberculosis_H37Rv ENMARLLIVTRERYHVFRHQQDTDESECVPVLMAALGKITGYDTATGAGS Mb2597|M.bovis_AF2122/97 ENMARLLIVTRERYHVFRHQQDTDESECVPVLMAALGKITGYDTATGAGS MMAR_2164|M.marinum_M ENMARLLMVARERYHLFRHHQDTEESECVPVLMAALGNITG----TDTGA MUL_1748|M.ulcerans_Agy99 ENMARLLMVARERYYLFRHHQDIEESECVPVLMAALGNITG----TDTGA MAV_3438|M.avium_104 ESMARLLIVTRDRFHVYRHHQHSEESECVPVLMAALGRITGTDTGTGAAA MLBr_02679|M.leprae_Br4923 ENMARLLIVTREHYHDSRHRQNTEENACLPVLIAALGKITG----TDTGS MAB_2858c|M.abscessus_ATCC_199 ENLVRLLSVTRERFHEYRYRQFMEASECVPVLLKALGDITG--------- * .*** *:*:::: *::: : . *:***: *** *.* Mflv_3770|M.gilvum_PYR-GCK AGDYAEMVATAPTTLWSLTADRHRPGSLAQSVERLGLAARAVRDQMSNDT Mvan_2629|M.vanbaalenii_PYR-1 GGDYTEMVATAPTTLWSLTADRHRAGSLAQSVERLGLTARAVRDQMSNDT MSMEG_3017|M.smegmatis_MC2_155 RDDDHEAIATAPTTLWSVTADRYRPGSLAQSVERLGLAARAVRDQMSNDT Rv2567|M.tuberculosis_H37Rv AYDRADMIAVAPSTLWSLTVDPDRPGSLVQSVEGLALAAQAVRDQLSNDT Mb2597|M.bovis_AF2122/97 AYDRADMIAVAPSTLWSLTVDPDRPGSLVQSVEGLALAARAVRDQLSNDT MMAR_2164|M.marinum_M ANDHAEMIAVAPSMLWSMTVDLEWPGSLVQSVEGLALAARAVRDQLSNDT MUL_1748|M.ulcerans_Agy99 ANDHAEMIAVAPSMLWSMTVDLEWPGSLVQSVEGLALAARAVRDQLSNDT MAV_3438|M.avium_104 GGDAAETIAVAPSTLWSLTVDPQRPGSLVQSVEGLALAARAVRDQMSNDT MLBr_02679|M.leprae_Br4923 G-GQADVIAVAPSTLWSLTTDRNLPGSLVQSVDGLVLAARAVRAQLSRDT MAB_2858c|M.abscessus_ATCC_199 ---TDTAAEDLGTQLWSLTVDKERSGSLAQSVERLGLAARAVRDQMSNDT : ***:*.* .***.***: * *:*:*** *:*.** Mflv_3770|M.gilvum_PYR-GCK WMVLSALDRALLNAPDTPPDSQAEGDA-------FLASTNTLALAGMMAL Mvan_2629|M.vanbaalenii_PYR-1 WMVLSALERTLLNAPGVPPDSQAEGDA-------FLARASTLTLGGMLAL MSMEG_3017|M.smegmatis_MC2_155 WMVLAGVERAVLRTSSIPPDSHSAGET-------YLANAHSQTLAGMLAL Rv2567|M.tuberculosis_H37Rv WMVLANVERAVEHKS-DPPQSLAEADA-------VLASAQAETLAGMLTL Mb2597|M.bovis_AF2122/97 WMVLANVERAVEHKS-DPPQSLAEADA-------VLASAQAETLAGMLTL MMAR_2164|M.marinum_M WIVLADVERAVTLRS-DPPQSLAEADG-------LLAEAQAQTLAGMLTL MUL_1748|M.ulcerans_Agy99 WIVLADVERAVTLRS-DPPQSLAEADG-------LLAEAQAQTLAGMLTL MAV_3438|M.avium_104 WMVLAGVERALALDS-EPPDSLAEADA-------LLTAAQTQTLAGMLTL MLBr_02679|M.leprae_Br4923 WMVLSEVERAMVHET-EPPESLVEGDA-------LLASVQARTLAGMLTL MAB_2858c|M.abscessus_ATCC_199 WMVLGGMDRAIAAAAAEYDEFRRSGDAPTRADDTVLAATQTQVLAGLLAL *:**. ::*:: . : .: *: . : .*.*:::* Mflv_3770|M.gilvum_PYR-GCK SGVAAESMVHDVGWTMMDIGKRIERGLALTALLRATLTTVRTPGAEQTVT Mvan_2629|M.vanbaalenii_PYR-1 SGVVAESMVHDVGWMMMDTGKRIERALALTALLRATLTTVRTPGAERTVT MSMEG_3017|M.smegmatis_MC2_155 SGVVSESMVQDIGWTMMDIGKRIERGLHLTALLRATLAQVHSPAAEHAVA Rv2567|M.tuberculosis_H37Rv SGVAGESMVHDVGWTMMDIGKRIERGLWLTALLQATLSTVRHPAAEQAII Mb2597|M.bovis_AF2122/97 SGVAGESMVHDVGWTMMDIGKRIERGLWLTALLQATLSTVRHPAAEQAII MMAR_2164|M.marinum_M SGVASESMVRDVGWTMMDIGKRIERGLWLTALLADTLTTVRGVVAEQTII MUL_1748|M.ulcerans_Agy99 SGVASESMVRDVGWTMMDIGKRIERGLWLTALLADTLTTVRGVVAEQTII MAV_3438|M.avium_104 SGVAGESMVRDVGWTMMDIGKRIERGLWLTALLRATLTVVRGAAAEQTIL MLBr_02679|M.leprae_Br4923 SGLAGESMVRDIGWTIMDIGKRIERGLALTALLHATLTDVRSPAAEHSII MAB_2858c|M.abscessus_ATCC_199 SGLAAESTVHDIGWTIMDIGKRIERGLGLTALLRSTLTTERGRAAEQSVT **:..** *:*:** :** ******.* ***** **: : **::: Mflv_3770|M.gilvum_PYR-GCK ESALVACESLVIYRRRNPGKISVAGVADLMLFDADNPRSLAYQLERLRTH Mvan_2629|M.vanbaalenii_PYR-1 ESTLVACESLVIYRRRNPGKISVAGLTELVLFDAGNPRSLVYQLERLRSH MSMEG_3017|M.smegmatis_MC2_155 ESTLVACESSVIYRRRNPGRISVAAIAELVLFDAENPRSLIYQLERLRTR Rv2567|M.tuberculosis_H37Rv EATLVACESSVIYRRRTVGKFSVAAVTELMLFDAQNPRSLVYQLERLRAD Mb2597|M.bovis_AF2122/97 EATLVACESSVIYRRRTVGKFSVAAVTELMLFDAQNPRSLVYQLERLRAD MMAR_2164|M.marinum_M ESTLEVCESSVIYRRRTVGKFSVTAVNELMLFDAHNPRSLVYQMERLRAN MUL_1748|M.ulcerans_Agy99 ESTLEVCESSVIYRRRTVGKFRVTAVNELMLFDAHNPRSLIYQLERLRAN MAV_3438|M.avium_104 ESTLVACESSVSYRRRTAGKVSVAAMAELMLFDAQNPRSLLYQVERLRAD MLBr_02679|M.leprae_Br4923 ESILVICESSVIYQRRTVSTIDVAVVAELMLFDATNPRSLVYQLDRLRVD MAB_2858c|M.abscessus_ATCC_199 ESTLVACESSVMYRRRTRGKISLEAVADLLLFDADNPRSLLYQVESLRTD *: * *** * *:**. . . : : :*:**** ***** **:: ** Mflv_3770|M.gilvum_PYR-GCK LRSLPESTGSSRPERMVDEIAARLRRMEPGELEEVAADGTRDGLRALLTA Mvan_2629|M.vanbaalenii_PYR-1 LKSLPGSSGSSRPERMVDEIAARLRRIEPAELEAVTADGRRAEFDGLLSG MSMEG_3017|M.smegmatis_MC2_155 LKTLPGSSGSSRSERLVDEIATRLRRLDPDDLETVT-DGMRVELADLLDA Rv2567|M.tuberculosis_H37Rv LKDLPGSSGSSRPERMVDEMNTRLRRSHPEELEEVSADGLRAELAELLAG Mb2597|M.bovis_AF2122/97 LKDLPGSSGSSRPERMVDEMNTRLRRSHPEELEEVSADGLRAELAELLAG MMAR_2164|M.marinum_M LKDLPGTSGSSRPERMVDEISARLRRSHPAELEEIT-DGRRTELAELLNG MUL_1748|M.ulcerans_Agy99 LEDLPGTSGSSRPERMVGEISARLRRSHPAELEEIT-DGRRTELAELLNG MAV_3438|M.avium_104 LKDLPGASGSSRPERLVDEIGTRLRRSHPAELERISDDGRRTELAELLDS MLBr_02679|M.leprae_Br4923 LADLPGSSRSSLPERMVAEMSTRLRRSAPAQLKEVSADGRRYVLAELLAA MAB_2858c|M.abscessus_ATCC_199 LKSLPSASGTSRPERLVEDLVTQLRRIDPADLETTGEQGLRDTLAETLDS * ** :: :* .**:* :: ::*** * :*: :* * : * . Mflv_3770|M.gilvum_PYR-GCK IHRDLRELSAVITTVHLSLPGDMQPLWGPDERRVVP- Mvan_2629|M.vanbaalenii_PYR-1 IHHDLRELSSAITAVHLSLPGDMQPLWGPDERRVVP- MSMEG_3017|M.smegmatis_MC2_155 IHIGLRDLATVITAAHLSVPGGMQPLWGPDERRILP- Rv2567|M.tuberculosis_H37Rv IHASLRDVADVLTATQLALPGGMQPLWGPDQRRVMPA Mb2597|M.bovis_AF2122/97 IHASLRDVADVLTATQLALPGGMQPLWGPDQRRVMPA MMAR_2164|M.marinum_M IHVSLRELAEVITDTQLALPGGMQPLWGPEERRTMPA MUL_1748|M.ulcerans_Agy99 IHVSLRELAEVITDTQLALPGGMQPLWGPEERRTMPA MAV_3438|M.avium_104 VHAELRSLAEVLTTTQLALPGGMQPLWGPDVRRVMPA MLBr_02679|M.leprae_Br4923 VDTALRDLADAITATQLAVPCGMQPLWGPDNRQTMS- MAB_2858c|M.abscessus_ATCC_199 VHHALRELSSVVTATHLSMPTGMQPLWGPDTRRRLP- :. **.:: .:* .:*::* .*******: *: :.