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KSTVEQLSPTRVRINVEVPFAELEPDFQRAYKELAKQVRLPGFRPGKAPAKLLEARIGREAMLDQIVNDA LPSRYGQAVAESDVQPLGRPNIEVTKKEYGQDLQFTAEVDIRPKISPPDLSALTVSVDPIEIGEDDVDAE LQSLRTRFGTLTAVDRPVAVGDVVSIDLSATVDGEDIPNAAAEGLSHEVGSGRLIAGLDDAVVGLSADES RVFTAKLAAGEHAGQEAQVTVTVRSVKERELPEPDDEFAQLASEFDSIDELRASLSDQVRQAKRAQQAEQ IRNATIDALLEQVDVPLPESYVQAQFDSVLHSALSGLNHDEARFNELLVEQGSSRAAFDAEARTASEKDV KRQLLLDALADELQVQVGQDDLTERLVTTSRQYGIEPQQLFGYLQERNQLPTMFADVRRELAIRAAVEAA TVTDSDGNTIDTSEFFGKRVSAGEAEEAEPADEGAARAASDEATT*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. tuberculosis H37Rv | Rv2462c | tig | - | 100% (466) | trigger factor |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2489c | tig | 0.0 | 99.79% (466) | trigger factor |
M. gilvum PYR-GCK | Mflv_2587 | tig | 1e-170 | 63.44% (465) | trigger factor |
M. leprae Br4923 | MLBr_01481 | tig | 0.0 | 69.66% (468) | trigger factor |
M. abscessus ATCC 19977 | MAB_1580 | - | 1e-156 | 61.17% (461) | trigger factor (TF) |
M. marinum M | MMAR_3809 | tig | 0.0 | 79.58% (480) | trigger factor (TF) protein TIG |
M. avium 104 | MAV_1712 | tig | 0.0 | 75.22% (464) | trigger factor |
M. smegmatis MC2 155 | MSMEG_4674 | tig | 0.0 | 69.10% (466) | trigger factor |
M. thermoresistible (build 8) | TH_0351 | tig | 0.0 | 68.80% (468) | PROBABLE TRIGGER FACTOR (TF) PROTEIN TIG |
M. ulcerans Agy99 | MUL_3732 | tig | 0.0 | 84.51% (439) | trigger factor |
M. vanbaalenii PYR-1 | Mvan_4041 | tig | 1e-171 | 64.53% (468) | trigger factor |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_2587|M.gilvum_PYR-GCK MKSTVEKLSPTRVRINVEVPFAELEPDIDKAFKQLAQQIRLPGFRPGKAP Mvan_4041|M.vanbaalenii_PYR-1 MKSTVEKLSPTRVRINVEVPFTELEPDIDRAFKQLAKQIRLPGFRPGKAP MSMEG_4674|M.smegmatis_MC2_155 MKSTVEQLSPTRVRINVEVPFTELEPDFDRAFKELAKQVRLPGFRPGKAP MAB_1580|M.abscessus_ATCC_1997 MKSTVEKLSPTRVRINVEVPFAELEPDFSKAYKELAQQVRLPGFRPGKAP TH_0351|M.thermoresistible__bu VKSTVEKLSPTRVRINVEVPFTELQPDFDRAYKELAKQVRLPGFRPGKAP Rv2462c|M.tuberculosis_H37Rv MKSTVEQLSPTRVRINVEVPFAELEPDFQRAYKELAKQVRLPGFRPGKAP Mb2489c|M.bovis_AF2122/97 MKSTVEQLSPTRVRINVEVPFAELEPDFQRAYKELAKQVRLPGFRPGKAP MMAR_3809|M.marinum_M MKSSVEQLSPTRVRIKVEVPFAELEPDFQRAYKELAKQVRLPGFRPGRAP MUL_3732|M.ulcerans_Agy99 MKSSVEQLSPTRVRIKVEVPFAELEPDFQRAYKELAKQVRLPGFRPGRAP MLBr_01481|M.leprae_Br4923 MKSSVEQLNPTRVRINVEVPFTELEPDFQRAYKELARHVQLPGFRPGKVP MAV_1712|M.avium_104 MKSTVEQLSPTRVRINVEVPFAELEPDFQRAYKELAKQVRLPGFRPGKAP :**:**:*.******:*****:**:**:.:*:*:**::::*******:.* Mflv_2587|M.gilvum_PYR-GCK RKLLEARVGRGAVLEQVVNDALPTRYSQAVTSESLQPIGQPEIEVTKLED Mvan_4041|M.vanbaalenii_PYR-1 RKLLEARVGRGAVLEQVVNDALPARYSEAVTAESLQPIGQPEIEVTKLED MSMEG_4674|M.smegmatis_MC2_155 RKLLEARIGRGAVLEQVVNDALPSRYSEAVSTSDLKPLGQPEIEITKLED MAB_1580|M.abscessus_ATCC_1997 AKLLEARVGRAAVLEQVVNAALPARYSEAVTASDVKPLGQPEIEVTKIED TH_0351|M.thermoresistible__bu AKLLEARIGREAMLDQVVSDAIPARYSEAVASSDVRPLGQPDIEITKKEY Rv2462c|M.tuberculosis_H37Rv AKLLEARIGREAMLDQIVNDALPSRYGQAVAESDVQPLGRPNIEVTKKEY Mb2489c|M.bovis_AF2122/97 AKLLEARIGREAMLDQIVNDALPSRYGQAVAESDVQPLGRPNIEVTKKEY MMAR_3809|M.marinum_M VKLLEARFGREAMLDQIVNDAVPSRYGQALAESEIQPLGRPDIEVTQKEY MUL_3732|M.ulcerans_Agy99 VKLLEARFGREAMLDQIVNDAVPSRYGQALAESEIQPLGRPDIEVTQKEY MLBr_01481|M.leprae_Br4923 ARLLEARFGRETLLDQVVNEAMPSRYGQALAESEVQPIGQPEIEVIRKEY MAV_1712|M.avium_104 AKLLEARFGREAMLDQVVTEALPARYGQAVAESEVHPLGQPEIEVTKKEY :*****.** ::*:*:*. *:*:**.:*:: ..::*:*:*:**: : * Mflv_2587|M.gilvum_PYR-GCK NEELVFTAEVDVRPEIDLPDLSTLTITVDPVSVTDEDIEAEIEALQKRFG Mvan_4041|M.vanbaalenii_PYR-1 NEELVFTAEVDVRPDIDLPDLGALKITVDPISVTDEDVDAEIEALQKRFG MSMEG_4674|M.smegmatis_MC2_155 NEELVFTAEVDIRPEITLPELESLKITVDPIEVTDEEVDAELQSLRARFG MAB_1580|M.abscessus_ATCC_1997 GQELTFTAEVDVRPEIELPDLSGVAVTVKPVTVEDSEVEAELDALRARFG TH_0351|M.thermoresistible__bu GETIEFTAEVDIRPDIELPDLEALKIKVDPIEVTDEDIDAELQNLRARFG Rv2462c|M.tuberculosis_H37Rv GQDLQFTAEVDIRPKISPPDLSALTVSVDPIEIGEDDVDAELQSLRTRFG Mb2489c|M.bovis_AF2122/97 GQDLQFTAEVDIRPKISLPDLSALTVSVDPIEIGEDDVDAELQSLRTRFG MMAR_3809|M.marinum_M GQDLAFTAEVDVRPEIALPDLTGLSVSVDAIEATDDEVNAELESLRARFG MUL_3732|M.ulcerans_Agy99 GQDLAFTAEVDVRPEIALPDLTGLSVSVDAIEATDDEVNAELESLRARFG MLBr_01481|M.leprae_Br4923 GQDLAFTVEVEVRPKIALPDFSTLKVVVDPVEVSTDDVEAELRSLRARFG MAV_1712|M.avium_104 GQELAFTAEVDVRPELNLPDPGALKISVDPIEVTDEDVDAELQSLRARFG .: : **.**::**.: *: : : *..: .:::**: *: *** Mflv_2587|M.gilvum_PYR-GCK TLTGVERPAENGDFVSIDLSATVDGKDVPEAKTEGLSHELGSGQLIEGLD Mvan_4041|M.vanbaalenii_PYR-1 TLTGVDRAAEDGDFVSIDLSATVDGKDVPEANTEGLSHEVGSGQLIEGLD MSMEG_4674|M.smegmatis_MC2_155 TLKGVERGVQEGDFVSIDLSATVDGNEVPEAATEGLSHEVGSGQLIDGLD MAB_1580|M.abscessus_ATCC_1997 TLKGVERAAENGDFVSIDLSATVDGKEVEEAATTGLSHEIGSGQLIDGLD TH_0351|M.thermoresistible__bu TLKGVERPVQDGDFVSIDLSATVDGTPVPEAATEGLSHEVGSGQLIEGLD Rv2462c|M.tuberculosis_H37Rv TLTAVDRPVAVGDVVSIDLSATVDGEDIPNAAAEGLSHEVGSGRLIAGLD Mb2489c|M.bovis_AF2122/97 TLTAVDRPVAVGDVVSIDLSATVDGEDIPNAAAEGLSHEVGSGRLIAGLD MMAR_3809|M.marinum_M TLTEVERPVATGDFISIDLSAAVDGEDVPNAAAEGLSHEVGSGRLIAGLD MUL_3732|M.ulcerans_Agy99 TLTGVERPVATGDFISIDLSAAVDGEDVPNAAAEGLSHEVRSGRLIAGLD MLBr_01481|M.leprae_Br4923 TLIGVDRPVALGDFVSIDLSATINGEKVPNADAEGLSHEVGYGRLIAGLD MAV_1712|M.avium_104 TLTGVERPVAEGDFVSIDLSATIDGQEVPGATAQGLSHEVGSGRLIEGLD ** *:* . **.:******:::* : * : *****: *:** *** Mflv_2587|M.gilvum_PYR-GCK EAIIGLSEDESKTFTTTLVAGEHAGREAEVTVTVKSIKVRELPELDDEFA Mvan_4041|M.vanbaalenii_PYR-1 EAIIGLKADESKVFTTTLVAGEHAGQEAEVTVTVKSIKVRELPEVDDDFA MSMEG_4674|M.smegmatis_MC2_155 EAIIGLKADESKTFTTKLVAGEYAGQDAEVTVTVKSVKERELPEPDDEFA MAB_1580|M.abscessus_ATCC_1997 EAIIGLKAGEEKVFTTKLAAGEFAGQEAEVTVKVGSIKERELPDADDDFA TH_0351|M.thermoresistible__bu ETLVGMTEGETKTFTSKLVAGEHAGKEAEVTVTVKSVKERELPEPDDEFA Rv2462c|M.tuberculosis_H37Rv DAVVGLSADESRVFTAKLAAGEHAGQEAQVTVTVRSVKERELPEPDDEFA Mb2489c|M.bovis_AF2122/97 DAVVGLSADESRVFTAKLAAGEHAGQEAQVTVTVRSVKERELPEPDDEFA MMAR_3809|M.marinum_M DAVVGLSVDESRVFTAKLAAGDHAGRDAEVTVTVKSVKERELPEPDDEFA MUL_3732|M.ulcerans_Agy99 DAVVGLSVDESRVFTAKLAAGDHAGRDAEVTVTVKSVKERELPEPDDEFA MLBr_01481|M.leprae_Br4923 DALVGLSAGESRVFTTQLATSKHAGQDAEVIVTVKSVKERELPEPDDEFA MAV_1712|M.avium_104 EALIGMSVDESREFTTKLVSGEHAGQDAQVTVTVKSVKERELPEPDDEFA ::::*:. .* : **: *.:...**::*:* *.* *:* ****: **:** Mflv_2587|M.gilvum_PYR-GCK QLASEFDTMDELRADLREKVTRVKTVQQAEAIRDKAIEVLLEQTEVPLPE Mvan_4041|M.vanbaalenii_PYR-1 QLASEFDTVEELRADLKEKISRFKRVQQAEAIRDKAIEVLLEQTEIPVPE MSMEG_4674|M.smegmatis_MC2_155 QLASEYDTIEELRNSLVDQVRRLKSVQQAEQIRDKAIEALLEQTEVPLPE MAB_1580|M.abscessus_ATCC_1997 QLASEFDTIGELKDSLTEQVKGRKRIAQADEIRDETITALLDKIEIPVPE TH_0351|M.thermoresistible__bu QLASEFDTIEELRESLAEQVRRVKRVQQAEQIRDKALEVLLEQVEVPLPE Rv2462c|M.tuberculosis_H37Rv QLASEFDSIDELRASLSDQVRQAKRAQQAEQIRNATIDALLEQVDVPLPE Mb2489c|M.bovis_AF2122/97 QLASEFDSIDELRASLSDQVRQAKRAQQAEQIRNATIDALLEQVDVPLPE MMAR_3809|M.marinum_M QLASEFDTIDELRASLREQVLQAKRVGQAEQIRNATIDALLERVDVPTPE MUL_3732|M.ulcerans_Agy99 QLASEFDTIDELRASLREQVLQAKRVGQAEQIRNATIDALLERVDVPTPE MLBr_01481|M.leprae_Br4923 QLVSEFDTMAELRANLGDQVRKAKYAQQAEKIRDAAVDALLERVDVPLPE MAV_1712|M.avium_104 QLASEFDTIDELRANLREQVGRVKRAQQAERIRDAAIDTLLEQVDIPLPE **.**:*:: **: .* ::: * **: **: :: .**:: ::* ** Mflv_2587|M.gilvum_PYR-GCK AVVQAQVDDTLHNAIHGLDHDEDRFADSLKEQGSSREEFDADNRANAEKA Mvan_4041|M.vanbaalenii_PYR-1 AVVQAQVDDTLHNAIHGLDHDEDKFAESLKEQGSSREEFDADNRANAEKA MSMEG_4674|M.smegmatis_MC2_155 KIVQAQIDEVVHNAIHGLDHDEEKFAEQLAEQGSSREEFDAETRTEAEKA MAB_1580|M.abscessus_ATCC_1997 KILEEQIGNNLHEAVHGLDHNEERLNELLQEQGSSREEFDKDMRESATKS TH_0351|M.thermoresistible__bu KAVQAQIDDTLHNAIHDLDHDEERFAEVLAARGSSREEFDAENRANAEKA Rv2462c|M.tuberculosis_H37Rv SYVQAQFDSVLHSALSGLNHDEARFNELLVEQGSSRAAFDAEARTASEKD Mb2489c|M.bovis_AF2122/97 SYVQAQFDSVLHSALSGLNHDEARFNELLVEQGSSRAAFDAEARTASEKD MMAR_3809|M.marinum_M SYVQAQYEGVLHSALSGINNDEARFNELLVEQGSSRDAFDAEARTASEKD MUL_3732|M.ulcerans_Agy99 SYVQAQYEGVLHSALSGINNDEARFNELLVEQGSSRDAFDAEARTASEKD MLBr_01481|M.leprae_Br4923 GIVQAQFNNALHDALSGLGHDEAKFAEVLAERGSSREEFEAEARSAAERD MAV_1712|M.avium_104 AIVKAQVDSALHGALHSLNHDESKLEEVLAQQGKSREEFENETRTAAETD :: * :* *: .:.::* :: : * :*.** *: : * : Mflv_2587|M.gilvum_PYR-GCK IKTQLLMDAIADKLEIQVGQNDLSERLVLMSRQYGLEPQQLLQMLQQNNQ Mvan_4041|M.vanbaalenii_PYR-1 IKTQLLMDSIADKLEIQVGQNDLTERLVLMSRQYGLEPQQLLQMLQQNNQ MSMEG_4674|M.smegmatis_MC2_155 VKTQLLMDAVADKLEIQVSQNDLTERLVLMSRQYGLEPQQLIQILQQNNQ MAB_1580|M.abscessus_ATCC_1997 IKTELLLDVIADKFDINVDQQDLTERLVLMSRQYGIEPQQLVQYLTQQQQ TH_0351|M.thermoresistible__bu IKTQLLVDAIADHLEIQVGQEDITERLVLMSRQYGVEPQQMLAFLQQNNQ Rv2462c|M.tuberculosis_H37Rv VKRQLLLDALADELQVQVGQDDLTERLVTTSRQYGIEPQQLFGYLQERNQ Mb2489c|M.bovis_AF2122/97 VKRQLLLDALADELQVQVGQDDLTERLVTTSRQYGIEPQQLFGYLQERNQ MMAR_3809|M.marinum_M VKRQLLLDALADDLKVQVGQEDLTERLVLTSRQYGIEPQQLFAYLQENNQ MUL_3732|M.ulcerans_Agy99 VKRQLLLDALADDLKVQVGQEDLTERLVLTSRQYGIEPQQLFVYLQENNQ MLBr_01481|M.leprae_Br4923 VTRQLLLDVVADDQKIQVGQDDLNERLLATSQQYGVDAQQLFGFLRENNR MAV_1712|M.avium_104 VKKQLLLDALADKLQVQVGQEDLTERLVATSRQYGIEPQQLLAYLQENNQ :. :**:* :**. .::*.*:*:.***: *:***::.**:. * :.:: Mflv_2587|M.gilvum_PYR-GCK LPAMFADVRRGLTVAAVVYAATVTDTDGTEIDTTEFFGP-----SGDQAA Mvan_4041|M.vanbaalenii_PYR-1 LPAMFADVRRGLTVAAVVHGATVTDTDGAEIDTAEFFGP-----SGEQAE MSMEG_4674|M.smegmatis_MC2_155 LPAMFADVRRGLTIAAVVHAATVTDTDGNVIDTMEFFGP-----SGEQAA MAB_1580|M.abscessus_ATCC_1997 LPGLYVDVRRGKAIAEVIRQAKVTDSTGADVDVDAVLGPRRG--GADEAG TH_0351|M.thermoresistible__bu LPVMFADVRRGLAIAAVVHRATVTDTDGNVLDTSEFFGP------REKAE Rv2462c|M.tuberculosis_H37Rv LPTMFADVRRELAIRAAVEAATVTDSDGNTIDTSEFFGKR---------- Mb2489c|M.bovis_AF2122/97 LPTMFADVRRELAIRAAVEAATVTDSDGNTIDTSEFFGKR---------- MMAR_3809|M.marinum_M LPSMFADVRRELAVKAVAQAATVTDTDGNTIDTSEFFGKPPENDVTDLLD MUL_3732|M.ulcerans_Agy99 LPSMFADVRRELAVKAVAQAATVTDTDGNTIDTSEFFGKPPENDVTDLLD MLBr_01481|M.leprae_Br4923 LSSLVTDARRRLAVAAVVEAATFTDSDGNTIDTSEFFGKHAQ-------- MAV_1712|M.avium_104 LPAMFADVRRALAIAEVIRAATVTDTAGNTIDTSEFFGKR---------- *. : .*.** :: . *..**: * :*. .:* Mflv_2587|M.gilvum_PYR-GCK AQQGAGEDDSEAAVEVSEDTADDASEDDTADDTK-------- Mvan_4041|M.vanbaalenii_PYR-1 AEQ----DEAAPAEDATEETDADS--DEAADDSK-------- MSMEG_4674|M.smegmatis_MC2_155 EDS------AEESTDAAEGEAAED-----ADDTDK------- MAB_1580|M.abscessus_ATCC_1997 AEAEAAEEKPAKAKKSADSEKTDKSEKAEKKSKKKSKDDDAE TH_0351|M.thermoresistible__bu GGETEQAAGSGDAADDAPENAADESPENAADEA--------- Rv2462c|M.tuberculosis_H37Rv --------VSAG--EAEEAEPADEGAARAASDEATT------ Mb2489c|M.bovis_AF2122/97 --------VSAG--EAEEAEPADEGAARAASDEATT------ MMAR_3809|M.marinum_M DDADGDAGVDADGDTENSAEPADADSADAAQGAG-------- MUL_3732|M.ulcerans_Agy99 DDADGDAGVDADGDTENSAEPADADSADTAQGAG-------- MLBr_01481|M.leprae_Br4923 --------SDKADQKTEEADPNSDAIDEEVDEAAE------- MAV_1712|M.avium_104 --------PSGDGAADEDADQADESTTADAGE---------- .