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KSSVEQLNPTRVRINVEVPFTELEPDFQRAYKELARHVQLPGFRPGKVPARLLEARFGRETLLDQVVNEA MPSRYGQALAESEVQPIGQPEIEVIRKEYGQDLAFTVEVEVRPKIALPDFSTLKVVVDPVEVSTDDVEAE LRSLRARFGTLIGVDRPVALGDFVSIDLSATINGEKVPNADAEGLSHEVGYGRLIAGLDDALVGLSAGES RVFTTQLATSKHAGQDAEVIVTVKSVKERELPEPDDEFAQLVSEFDTMAELRANLGDQVRKAKYAQQAEK IRDAAVDALLERVDVPLPEGIVQAQFNNALHDALSGLGHDEAKFAEVLAERGSSREEFEAEARSAAERDV TRQLLLDVVADDQKIQVGQDDLNERLLATSQQYGVDAQQLFGFLRENNRLSSLVTDARRRLAVAAVVEAA TFTDSDGNTIDTSEFFGKHAQSDKADQKTEEADPNSDAIDEEVDEAAE*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. leprae Br4923 | MLBr_01481 | tig | - | 100% (469) | trigger factor |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2489c | tig | 0.0 | 69.87% (468) | trigger factor |
| M. gilvum PYR-GCK | Mflv_2587 | tig | 1e-156 | 58.17% (471) | trigger factor |
| M. tuberculosis H37Rv | Rv2462c | tig | 0.0 | 69.66% (468) | trigger factor |
| M. abscessus ATCC 19977 | MAB_1580 | - | 1e-141 | 53.25% (477) | trigger factor (TF) |
| M. marinum M | MMAR_3809 | tig | 0.0 | 68.72% (470) | trigger factor (TF) protein TIG |
| M. avium 104 | MAV_1712 | tig | 0.0 | 69.35% (460) | trigger factor |
| M. smegmatis MC2 155 | MSMEG_4674 | tig | 1e-164 | 61.59% (466) | trigger factor |
| M. thermoresistible (build 8) | TH_0351 | tig | 1e-169 | 61.62% (469) | PROBABLE TRIGGER FACTOR (TF) PROTEIN TIG |
| M. ulcerans Agy99 | MUL_3732 | tig | 0.0 | 68.72% (470) | trigger factor |
| M. vanbaalenii PYR-1 | Mvan_4041 | tig | 1e-157 | 58.69% (472) | trigger factor |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2587|M.gilvum_PYR-GCK MKSTVEKLSPTRVRINVEVPFAELEPDIDKAFKQLAQQIRLPGFRPGKAP
Mvan_4041|M.vanbaalenii_PYR-1 MKSTVEKLSPTRVRINVEVPFTELEPDIDRAFKQLAKQIRLPGFRPGKAP
MSMEG_4674|M.smegmatis_MC2_155 MKSTVEQLSPTRVRINVEVPFTELEPDFDRAFKELAKQVRLPGFRPGKAP
MAB_1580|M.abscessus_ATCC_1997 MKSTVEKLSPTRVRINVEVPFAELEPDFSKAYKELAQQVRLPGFRPGKAP
TH_0351|M.thermoresistible__bu VKSTVEKLSPTRVRINVEVPFTELQPDFDRAYKELAKQVRLPGFRPGKAP
Mb2489c|M.bovis_AF2122/97 MKSTVEQLSPTRVRINVEVPFAELEPDFQRAYKELAKQVRLPGFRPGKAP
Rv2462c|M.tuberculosis_H37Rv MKSTVEQLSPTRVRINVEVPFAELEPDFQRAYKELAKQVRLPGFRPGKAP
MMAR_3809|M.marinum_M MKSSVEQLSPTRVRIKVEVPFAELEPDFQRAYKELAKQVRLPGFRPGRAP
MUL_3732|M.ulcerans_Agy99 MKSSVEQLSPTRVRIKVEVPFAELEPDFQRAYKELAKQVRLPGFRPGRAP
MLBr_01481|M.leprae_Br4923 MKSSVEQLNPTRVRINVEVPFTELEPDFQRAYKELARHVQLPGFRPGKVP
MAV_1712|M.avium_104 MKSTVEQLSPTRVRINVEVPFAELEPDFQRAYKELAKQVRLPGFRPGKAP
:**:**:*.******:*****:**:**:.:*:*:**::::*******:.*
Mflv_2587|M.gilvum_PYR-GCK RKLLEARVGRGAVLEQVVNDALPTRYSQAVTSESLQPIGQPEIEVTKLED
Mvan_4041|M.vanbaalenii_PYR-1 RKLLEARVGRGAVLEQVVNDALPARYSEAVTAESLQPIGQPEIEVTKLED
MSMEG_4674|M.smegmatis_MC2_155 RKLLEARIGRGAVLEQVVNDALPSRYSEAVSTSDLKPLGQPEIEITKLED
MAB_1580|M.abscessus_ATCC_1997 AKLLEARVGRAAVLEQVVNAALPARYSEAVTASDVKPLGQPEIEVTKIED
TH_0351|M.thermoresistible__bu AKLLEARIGREAMLDQVVSDAIPARYSEAVASSDVRPLGQPDIEITKKEY
Mb2489c|M.bovis_AF2122/97 AKLLEARIGREAMLDQIVNDALPSRYGQAVAESDVQPLGRPNIEVTKKEY
Rv2462c|M.tuberculosis_H37Rv AKLLEARIGREAMLDQIVNDALPSRYGQAVAESDVQPLGRPNIEVTKKEY
MMAR_3809|M.marinum_M VKLLEARFGREAMLDQIVNDAVPSRYGQALAESEIQPLGRPDIEVTQKEY
MUL_3732|M.ulcerans_Agy99 VKLLEARFGREAMLDQIVNDAVPSRYGQALAESEIQPLGRPDIEVTQKEY
MLBr_01481|M.leprae_Br4923 ARLLEARFGRETLLDQVVNEAMPSRYGQALAESEVQPIGQPEIEVIRKEY
MAV_1712|M.avium_104 AKLLEARFGREAMLDQVVTEALPARYGQAVAESEVHPLGQPEIEVTKKEY
:*****.** ::*:*:*. *:*:**.:*:: ..::*:*:*:**: : *
Mflv_2587|M.gilvum_PYR-GCK NEELVFTAEVDVRPEIDLPDLSTLTITVDPVSVTDEDIEAEIEALQKRFG
Mvan_4041|M.vanbaalenii_PYR-1 NEELVFTAEVDVRPDIDLPDLGALKITVDPISVTDEDVDAEIEALQKRFG
MSMEG_4674|M.smegmatis_MC2_155 NEELVFTAEVDIRPEITLPELESLKITVDPIEVTDEEVDAELQSLRARFG
MAB_1580|M.abscessus_ATCC_1997 GQELTFTAEVDVRPEIELPDLSGVAVTVKPVTVEDSEVEAELDALRARFG
TH_0351|M.thermoresistible__bu GETIEFTAEVDIRPDIELPDLEALKIKVDPIEVTDEDIDAELQNLRARFG
Mb2489c|M.bovis_AF2122/97 GQDLQFTAEVDIRPKISLPDLSALTVSVDPIEIGEDDVDAELQSLRTRFG
Rv2462c|M.tuberculosis_H37Rv GQDLQFTAEVDIRPKISPPDLSALTVSVDPIEIGEDDVDAELQSLRTRFG
MMAR_3809|M.marinum_M GQDLAFTAEVDVRPEIALPDLTGLSVSVDAIEATDDEVNAELESLRARFG
MUL_3732|M.ulcerans_Agy99 GQDLAFTAEVDVRPEIALPDLTGLSVSVDAIEATDDEVNAELESLRARFG
MLBr_01481|M.leprae_Br4923 GQDLAFTVEVEVRPKIALPDFSTLKVVVDPVEVSTDDVEAELRSLRARFG
MAV_1712|M.avium_104 GQELAFTAEVDVRPELNLPDPGALKISVDPIEVTDEDVDAELQSLRARFG
.: : **.**::**.: *: : : *..: .:::**: *: ***
Mflv_2587|M.gilvum_PYR-GCK TLTGVERPAENGDFVSIDLSATVDGKDVPEAKTEGLSHELGSGQLIEGLD
Mvan_4041|M.vanbaalenii_PYR-1 TLTGVDRAAEDGDFVSIDLSATVDGKDVPEANTEGLSHEVGSGQLIEGLD
MSMEG_4674|M.smegmatis_MC2_155 TLKGVERGVQEGDFVSIDLSATVDGNEVPEAATEGLSHEVGSGQLIDGLD
MAB_1580|M.abscessus_ATCC_1997 TLKGVERAAENGDFVSIDLSATVDGKEVEEAATTGLSHEIGSGQLIDGLD
TH_0351|M.thermoresistible__bu TLKGVERPVQDGDFVSIDLSATVDGTPVPEAATEGLSHEVGSGQLIEGLD
Mb2489c|M.bovis_AF2122/97 TLTAVDRPVAVGDVVSIDLSATVDGEDIPNAAAEGLSHEVGSGRLIAGLD
Rv2462c|M.tuberculosis_H37Rv TLTAVDRPVAVGDVVSIDLSATVDGEDIPNAAAEGLSHEVGSGRLIAGLD
MMAR_3809|M.marinum_M TLTEVERPVATGDFISIDLSAAVDGEDVPNAAAEGLSHEVGSGRLIAGLD
MUL_3732|M.ulcerans_Agy99 TLTGVERPVATGDFISIDLSAAVDGEDVPNAAAEGLSHEVRSGRLIAGLD
MLBr_01481|M.leprae_Br4923 TLIGVDRPVALGDFVSIDLSATINGEKVPNADAEGLSHEVGYGRLIAGLD
MAV_1712|M.avium_104 TLTGVERPVAEGDFVSIDLSATIDGQEVPGATAQGLSHEVGSGRLIEGLD
** *:* . **.:******:::* : * : *****: *:** ***
Mflv_2587|M.gilvum_PYR-GCK EAIIGLSEDESKTFTTTLVAGEHAGREAEVTVTVKSIKVRELPELDDEFA
Mvan_4041|M.vanbaalenii_PYR-1 EAIIGLKADESKVFTTTLVAGEHAGQEAEVTVTVKSIKVRELPEVDDDFA
MSMEG_4674|M.smegmatis_MC2_155 EAIIGLKADESKTFTTKLVAGEYAGQDAEVTVTVKSVKERELPEPDDEFA
MAB_1580|M.abscessus_ATCC_1997 EAIIGLKAGEEKVFTTKLAAGEFAGQEAEVTVKVGSIKERELPDADDDFA
TH_0351|M.thermoresistible__bu ETLVGMTEGETKTFTSKLVAGEHAGKEAEVTVTVKSVKERELPEPDDEFA
Mb2489c|M.bovis_AF2122/97 DAVVGLSADESRVFTAKLAAGEHAGQEAQVTVTVRSVKERELPEPDDEFA
Rv2462c|M.tuberculosis_H37Rv DAVVGLSADESRVFTAKLAAGEHAGQEAQVTVTVRSVKERELPEPDDEFA
MMAR_3809|M.marinum_M DAVVGLSVDESRVFTAKLAAGDHAGRDAEVTVTVKSVKERELPEPDDEFA
MUL_3732|M.ulcerans_Agy99 DAVVGLSVDESRVFTAKLAAGDHAGRDAEVTVTVKSVKERELPEPDDEFA
MLBr_01481|M.leprae_Br4923 DALVGLSAGESRVFTTQLATSKHAGQDAEVIVTVKSVKERELPEPDDEFA
MAV_1712|M.avium_104 EALIGMSVDESREFTTKLVSGEHAGQDAQVTVTVKSVKERELPEPDDEFA
::::*:. .* : **: *.:...**::*:* *.* *:* ****: **:**
Mflv_2587|M.gilvum_PYR-GCK QLASEFDTMDELRADLREKVTRVKTVQQAEAIRDKAIEVLLEQTEVPLPE
Mvan_4041|M.vanbaalenii_PYR-1 QLASEFDTVEELRADLKEKISRFKRVQQAEAIRDKAIEVLLEQTEIPVPE
MSMEG_4674|M.smegmatis_MC2_155 QLASEYDTIEELRNSLVDQVRRLKSVQQAEQIRDKAIEALLEQTEVPLPE
MAB_1580|M.abscessus_ATCC_1997 QLASEFDTIGELKDSLTEQVKGRKRIAQADEIRDETITALLDKIEIPVPE
TH_0351|M.thermoresistible__bu QLASEFDTIEELRESLAEQVRRVKRVQQAEQIRDKALEVLLEQVEVPLPE
Mb2489c|M.bovis_AF2122/97 QLASEFDSIDELRASLSDQVRQAKRAQQAEQIRNATIDALLEQVDVPLPE
Rv2462c|M.tuberculosis_H37Rv QLASEFDSIDELRASLSDQVRQAKRAQQAEQIRNATIDALLEQVDVPLPE
MMAR_3809|M.marinum_M QLASEFDTIDELRASLREQVLQAKRVGQAEQIRNATIDALLERVDVPTPE
MUL_3732|M.ulcerans_Agy99 QLASEFDTIDELRASLREQVLQAKRVGQAEQIRNATIDALLERVDVPTPE
MLBr_01481|M.leprae_Br4923 QLVSEFDTMAELRANLGDQVRKAKYAQQAEKIRDAAVDALLERVDVPLPE
MAV_1712|M.avium_104 QLASEFDTIDELRANLREQVGRVKRAQQAERIRDAAIDTLLEQVDIPLPE
**.**:*:: **: .* ::: * **: **: :: .**:: ::* **
Mflv_2587|M.gilvum_PYR-GCK AVVQAQVDDTLHNAIHGLDHDEDRFADSLKEQGSSREEFDADNRANAEKA
Mvan_4041|M.vanbaalenii_PYR-1 AVVQAQVDDTLHNAIHGLDHDEDKFAESLKEQGSSREEFDADNRANAEKA
MSMEG_4674|M.smegmatis_MC2_155 KIVQAQIDEVVHNAIHGLDHDEEKFAEQLAEQGSSREEFDAETRTEAEKA
MAB_1580|M.abscessus_ATCC_1997 KILEEQIGNNLHEAVHGLDHNEERLNELLQEQGSSREEFDKDMRESATKS
TH_0351|M.thermoresistible__bu KAVQAQIDDTLHNAIHDLDHDEERFAEVLAARGSSREEFDAENRANAEKA
Mb2489c|M.bovis_AF2122/97 SYVQAQFDSVLHSALSGLNHDEARFNELLVEQGSSRAAFDAEARTASEKD
Rv2462c|M.tuberculosis_H37Rv SYVQAQFDSVLHSALSGLNHDEARFNELLVEQGSSRAAFDAEARTASEKD
MMAR_3809|M.marinum_M SYVQAQYEGVLHSALSGINNDEARFNELLVEQGSSRDAFDAEARTASEKD
MUL_3732|M.ulcerans_Agy99 SYVQAQYEGVLHSALSGINNDEARFNELLVEQGSSRDAFDAEARTASEKD
MLBr_01481|M.leprae_Br4923 GIVQAQFNNALHDALSGLGHDEAKFAEVLAERGSSREEFEAEARSAAERD
MAV_1712|M.avium_104 AIVKAQVDSALHGALHSLNHDESKLEEVLAQQGKSREEFENETRTAAETD
:: * :* *: .:.::* :: : * :*.** *: : * :
Mflv_2587|M.gilvum_PYR-GCK IKTQLLMDAIADKLEIQVGQNDLSERLVLMSRQYGLEPQQLLQMLQQNNQ
Mvan_4041|M.vanbaalenii_PYR-1 IKTQLLMDSIADKLEIQVGQNDLTERLVLMSRQYGLEPQQLLQMLQQNNQ
MSMEG_4674|M.smegmatis_MC2_155 VKTQLLMDAVADKLEIQVSQNDLTERLVLMSRQYGLEPQQLIQILQQNNQ
MAB_1580|M.abscessus_ATCC_1997 IKTELLLDVIADKFDINVDQQDLTERLVLMSRQYGIEPQQLVQYLTQQQQ
TH_0351|M.thermoresistible__bu IKTQLLVDAIADHLEIQVGQEDITERLVLMSRQYGVEPQQMLAFLQQNNQ
Mb2489c|M.bovis_AF2122/97 VKRQLLLDALADELQVQVGQDDLTERLVTTSRQYGIEPQQLFGYLQERNQ
Rv2462c|M.tuberculosis_H37Rv VKRQLLLDALADELQVQVGQDDLTERLVTTSRQYGIEPQQLFGYLQERNQ
MMAR_3809|M.marinum_M VKRQLLLDALADDLKVQVGQEDLTERLVLTSRQYGIEPQQLFAYLQENNQ
MUL_3732|M.ulcerans_Agy99 VKRQLLLDALADDLKVQVGQEDLTERLVLTSRQYGIEPQQLFVYLQENNQ
MLBr_01481|M.leprae_Br4923 VTRQLLLDVVADDQKIQVGQDDLNERLLATSQQYGVDAQQLFGFLRENNR
MAV_1712|M.avium_104 VKKQLLLDALADKLQVQVGQEDLTERLVATSRQYGIEPQQLLAYLQENNQ
:. :**:* :**. .::*.*:*:.***: *:***::.**:. * :.::
Mflv_2587|M.gilvum_PYR-GCK LPAMFADVRRGLTVAAVVYAATVTDTDGTEIDTTEFFGP-----SGDQAA
Mvan_4041|M.vanbaalenii_PYR-1 LPAMFADVRRGLTVAAVVHGATVTDTDGAEIDTAEFFGP-----SGEQAE
MSMEG_4674|M.smegmatis_MC2_155 LPAMFADVRRGLTIAAVVHAATVTDTDGNVIDTMEFFGP-----SGEQAA
MAB_1580|M.abscessus_ATCC_1997 LPGLYVDVRRGKAIAEVIRQAKVTDSTGADVDVDAVLGPRRG--GADEAG
TH_0351|M.thermoresistible__bu LPVMFADVRRGLAIAAVVHRATVTDTDGNVLDTSEFFGP------REKAE
Mb2489c|M.bovis_AF2122/97 LPTMFADVRRELAIRAAVEAATVTDSDGNTIDTSEFFGKR----------
Rv2462c|M.tuberculosis_H37Rv LPTMFADVRRELAIRAAVEAATVTDSDGNTIDTSEFFGKR----------
MMAR_3809|M.marinum_M LPSMFADVRRELAVKAVAQAATVTDTDGNTIDTSEFFGKPPENDVTDLLD
MUL_3732|M.ulcerans_Agy99 LPSMFADVRRELAVKAVAQAATVTDTDGNTIDTSEFFGKPPENDVTDLLD
MLBr_01481|M.leprae_Br4923 LSSLVTDARRRLAVAAVVEAATFTDSDGNTIDTSEFFGKHAQ--------
MAV_1712|M.avium_104 LPAMFADVRRALAIAEVIRAATVTDTAGNTIDTSEFFGKR----------
*. : .*.** :: . *..**: * :*. .:*
Mflv_2587|M.gilvum_PYR-GCK AQQGAGEDDSEAAVEVSEDTADDASEDDTADDTK--------
Mvan_4041|M.vanbaalenii_PYR-1 AEQ----DEAAPAEDATEETDADS--DEAADDSK--------
MSMEG_4674|M.smegmatis_MC2_155 EDS------AEESTDAAEGEAAED-----ADDTDK-------
MAB_1580|M.abscessus_ATCC_1997 AEAEAAEEKPAKAKKSADSEKTDKSEKAEKKSKKKSKDDDAE
TH_0351|M.thermoresistible__bu GGETEQAAGSGDAADDAPENAADESPENAADEA---------
Mb2489c|M.bovis_AF2122/97 --------VSAG--EAEEAEPADEGAARAASDEATT------
Rv2462c|M.tuberculosis_H37Rv --------VSAG--EAEEAEPADEGAARAASDEATT------
MMAR_3809|M.marinum_M DDADGDAGVDADGDTENSAEPADADSADAAQGAG--------
MUL_3732|M.ulcerans_Agy99 DDADGDAGVDADGDTENSAEPADADSADTAQGAG--------
MLBr_01481|M.leprae_Br4923 --------SDKADQKTEEADPNSDAIDEEVDEAAE-------
MAV_1712|M.avium_104 --------PSGDGAADEDADQADESTTADAGE----------
.