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ARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEELADADDVKLDELPKPAEIREFL EGYVIGQDTAKRTLAVAVYNHYKRIQAGEKGRDSRCEPVELTKSNILMLGPTGCGKTYLAQTLAKMLNVP FAIADATALTEAGYVGEDVENILLKLIQAADYDVKRAETGIIYIDEVDKIARKSENPSITRDVSGEGVQQ ALLKILEGTQASVPPQGGRKHPHQEFIQIDTTNVLFIVAGAFAGLEKIIYERVGKRGLGFGAEVRSKAEI DTTDHFADVMPEDLIKFGLIPEFIGRLPVVASVTNLDKESLVKILSEPKNALVKQYIRLFEMDGVELEFT DDALEAIADQAIHRGTGARGLRAIMEEVLLPVMYDIPSRDDVAKVVVTKETVQDNVLPTIVPRKPSRSER RDKSA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2457c | clpX | - | 100% (426) | ATP-dependent protease ATP-binding subunit |
| M. tuberculosis H37Rv | Rv2592c | ruvB | 5e-06 | 27.34% (139) | Holliday junction DNA helicase RuvB |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2484c | clpX | 0.0 | 100.00% (426) | ATP-dependent protease ATP-binding subunit ClpX |
| M. gilvum PYR-GCK | Mflv_2591 | clpX | 0.0 | 96.48% (426) | ATP-dependent protease ATP-binding subunit |
| M. leprae Br4923 | MLBr_01477 | clpX | 0.0 | 96.01% (426) | ATP-dependent protease ATP-binding subunit ClpX |
| M. abscessus ATCC 19977 | MAB_1583 | clpX | 0.0 | 94.13% (426) | ATP-dependent protease ATP-binding subunit ClpX |
| M. marinum M | MMAR_3805 | clpX | 0.0 | 98.83% (426) | ATP-dependent Clp protease ATP-binding subunit ClpX |
| M. avium 104 | MAV_1716 | clpX | 0.0 | 98.59% (426) | ATP-dependent protease ATP-binding subunit |
| M. smegmatis MC2 155 | MSMEG_4671 | clpX | 0.0 | 97.18% (426) | ATP-dependent protease ATP-binding subunit |
| M. thermoresistible (build 8) | TH_0353 | clpX | 0.0 | 94.60% (426) | PROBABLE ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX |
| M. ulcerans Agy99 | MUL_3728 | clpX | 0.0 | 98.59% (426) | ATP-dependent protease ATP-binding subunit ClpX |
| M. vanbaalenii PYR-1 | Mvan_4036 | clpX | 0.0 | 96.01% (426) | ATP-dependent protease ATP-binding subunit |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2591|M.gilvum_PYR-GCK MARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEEL
Mvan_4036|M.vanbaalenii_PYR-1 MARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEEL
Rv2457c|M.tuberculosis_H37Rv MARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEEL
Mb2484c|M.bovis_AF2122/97 MARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEEL
MLBr_01477|M.leprae_Br4923 MARIGDSGDLLKCSFCGKSQTQVKKLIAGPGVYICDECIDLCNEIIEEEL
MAV_1716|M.avium_104 MARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEEL
MMAR_3805|M.marinum_M MARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEEL
MUL_3728|M.ulcerans_Agy99 MARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEEL
MSMEG_4671|M.smegmatis_MC2_155 MARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEEL
TH_0353|M.thermoresistible__bu MARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEEL
MAB_1583|M.abscessus_ATCC_1997 MARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEEL
******.*************.*****************************
Mflv_2591|M.gilvum_PYR-GCK ADADDVKLDELPKPAEIRDFLEGYVIGQDTAKRTLAVAVYNHYKRIQAGE
Mvan_4036|M.vanbaalenii_PYR-1 ADADDVKLDELPKPAEIREFLEGYVIGQDTAKRTLAVAVYNHYKRIQAGE
Rv2457c|M.tuberculosis_H37Rv ADADDVKLDELPKPAEIREFLEGYVIGQDTAKRTLAVAVYNHYKRIQAGE
Mb2484c|M.bovis_AF2122/97 ADADDVKLDELPKPAEIREFLEGYVIGQDTAKRTLAVAVYNHYKRIQAGE
MLBr_01477|M.leprae_Br4923 ADADDVQLDELPKPVEIREFLEGYVIGQDTAKRTLAVAVYNHYKRIQAGE
MAV_1716|M.avium_104 ADADDVKLDELPKPIEIREFLEGYVIGQDTAKRTLAVAVYNHYKRIQAGE
MMAR_3805|M.marinum_M ADADDVKLDELPKPVEIREFLEGYVIGQDTAKRTLAVAVYNHYKRIQAGE
MUL_3728|M.ulcerans_Agy99 ADADDVKLDELPKPVEIREFLEGYVIGQDTAKRTLAVAVYNHYKRIQAGE
MSMEG_4671|M.smegmatis_MC2_155 ADADDVKLDELPKPAEIREFLEGYVIGQDSAKRTLAVAVYNHYKRIQAGE
TH_0353|M.thermoresistible__bu ADADEVKLDELPKPAEIHEFLESYVIGQESAKRTLAVAVYNHYKRIQAGE
MAB_1583|M.abscessus_ATCC_1997 ADADDVKLDELPKPAEIRDFLENYVIGQDTAKKTLAVAVYNHYKRIQAGD
****:*:******* **::***.*****::**:****************:
Mflv_2591|M.gilvum_PYR-GCK KARDSRAEPVELAKSNILMLGPTGCGKTYLAQTLAKMLNVPFAIADATAL
Mvan_4036|M.vanbaalenii_PYR-1 KARDSRSEPVELAKSNILMLGPTGCGKTYLAQTLAKMLNVPFAIADATAL
Rv2457c|M.tuberculosis_H37Rv KGRDSRCEPVELTKSNILMLGPTGCGKTYLAQTLAKMLNVPFAIADATAL
Mb2484c|M.bovis_AF2122/97 KGRDSRCEPVELTKSNILMLGPTGCGKTYLAQTLAKMLNVPFAIADATAL
MLBr_01477|M.leprae_Br4923 KGRDSKREPVELAKSNILMLGPTGCGKTYLAQTLAKMLNVPFAIADATAL
MAV_1716|M.avium_104 KGRDSRHEPVELTKSNILMLGPTGCGKTYLAQTLAKMLNVPFAIADATAL
MMAR_3805|M.marinum_M KSRDSRCEAVELTKSNILMLGPTGCGKTYLAQTLAKMLNVPFAIADATAL
MUL_3728|M.ulcerans_Agy99 KSHDSRCEAVELTKSNILMLGPTGCGKTYLAQTLAKMLNVPFAIADATAL
MSMEG_4671|M.smegmatis_MC2_155 KSRDSRSEPVELTKSNILMLGPTGCGKTYLAQTLAKMLNVPFAIADATAL
TH_0353|M.thermoresistible__bu KSRDSRSEPVELAKSNILMLGPTGCGKTYLAQTLAKMLNVPFAIADATAL
MAB_1583|M.abscessus_ATCC_1997 KARDARGETVELAKSNILMLGPTGCGKTYLAQTLAKMLNVPFAIADATAL
*.:*:: *.***:*************************************
Mflv_2591|M.gilvum_PYR-GCK TEAGYVGEDVENILLKLIQAADYDVKRAETGIIYIDEVDKIARKSENPSI
Mvan_4036|M.vanbaalenii_PYR-1 TEAGYVGEDVENILLKLIQAADYDVKRAETGIIYIDEVDKIARKSENPSI
Rv2457c|M.tuberculosis_H37Rv TEAGYVGEDVENILLKLIQAADYDVKRAETGIIYIDEVDKIARKSENPSI
Mb2484c|M.bovis_AF2122/97 TEAGYVGEDVENILLKLIQAADYDVKRAETGIIYIDEVDKIARKSENPSI
MLBr_01477|M.leprae_Br4923 TEAGYVGEDVENILLKLIQAADYDVKRAETGIIYIDEVDKIARKSENPSI
MAV_1716|M.avium_104 TEAGYVGEDVENILLKLIQAADYDVKRAETGIIYIDEVDKIARKSENPSI
MMAR_3805|M.marinum_M TEAGYVGEDVENILLKLIQAADYDVKRAETGIIYIDEVDKIARKSENPSI
MUL_3728|M.ulcerans_Agy99 TEAGYVGEDVENILLKLIQAADYDVKRAETGIIYIDEVDKIARKSENPSI
MSMEG_4671|M.smegmatis_MC2_155 TEAGYVGEDVENILLKLIQAADYDVKRAETGIIYIDEVDKIARKSENPSI
TH_0353|M.thermoresistible__bu TEAGYVGEDVENILLKLIQAADYDVKRAETGIIYIDEVDKIARKSENPSI
MAB_1583|M.abscessus_ATCC_1997 TEAGYVGEDVENILLKLIQAADYDVKRAETGIIYIDEVDKIARKSENPSI
**************************************************
Mflv_2591|M.gilvum_PYR-GCK TRDVSGEGVQQALLKILEGTQASVPPQGGRKHPHQEFIQIDTTNVLFIVA
Mvan_4036|M.vanbaalenii_PYR-1 TRDVSGEGVQQALLKILEGTQASVPPQGGRKHPHQEFIQIDTTNVLFIVA
Rv2457c|M.tuberculosis_H37Rv TRDVSGEGVQQALLKILEGTQASVPPQGGRKHPHQEFIQIDTTNVLFIVA
Mb2484c|M.bovis_AF2122/97 TRDVSGEGVQQALLKILEGTQASVPPQGGRKHPHQEFIQIDTTNVLFIVA
MLBr_01477|M.leprae_Br4923 TRDVSGEGVQQALLKILEGTQASVPPQGGRKHPHQEFIQIDTTNVLFIVA
MAV_1716|M.avium_104 TRDVSGEGVQQALLKILEGTQASVPPQGGRKHPHQEFIQIDTTNVLFIVA
MMAR_3805|M.marinum_M TRDVSGEGVQQALLKILEGTQASVPPQGGRKHPHQEFIQIDTTNVLFIVA
MUL_3728|M.ulcerans_Agy99 TRDVSGEGVQQALLKILEGTQASVPPQGGRKHPHQEFIQIDTTNVLFIVA
MSMEG_4671|M.smegmatis_MC2_155 TRDVSGEGVQQALLKILEGTQASVPPQGGRKHPHQEFIQIDTTNVLFIVA
TH_0353|M.thermoresistible__bu TRDVSGEGVQQALLKILEGTQASVPPQGGRKHPHQEFIQIDTTNVLFIVA
MAB_1583|M.abscessus_ATCC_1997 TRDVSGEGVQQALLKILEGTQASVPPQGGRKHPHQEFIQIDTTNVLFIVA
**************************************************
Mflv_2591|M.gilvum_PYR-GCK GAFAGLEKIVSDRVGKRGLGFGAEVHSKAEIDTQDHFAEVMPEDLIKFGL
Mvan_4036|M.vanbaalenii_PYR-1 GAFAGLERIVSDRVGKRGLGFGAEVKSKAEIDTQDHFAEVMPEDLIKFGL
Rv2457c|M.tuberculosis_H37Rv GAFAGLEKIIYERVGKRGLGFGAEVRSKAEIDTTDHFADVMPEDLIKFGL
Mb2484c|M.bovis_AF2122/97 GAFAGLEKIIYERVGKRGLGFGAEVRSKAEIDTTDHFADVMPEDLIKFGL
MLBr_01477|M.leprae_Br4923 GAFAGLDKIIYERIGKRGLGFGAEVRSKAEIDTTDHFADVMPEDLIKFGL
MAV_1716|M.avium_104 GAFAGLEKIIYERVGKRGLGFGAEVRSKAEIDTTDHFAEVMPEDLIKFGL
MMAR_3805|M.marinum_M GAFAGLEKIIYERVGKRGLGFGAEVRSKAEIDTTDHFAEVMPEDLIKFGL
MUL_3728|M.ulcerans_Agy99 GAFAGLEKIIYERVGKRGLGFGAEVRSKAEIDTTDHFAEVMPEDLIKFGL
MSMEG_4671|M.smegmatis_MC2_155 GAFAGLEKIVSDRVGKRGLGFGAEVRSKAEIDTQDHFAEVMPEDLIKFGL
TH_0353|M.thermoresistible__bu GAFAGLEKIVQDRVGKRGLGFGAEVHSKSEIDTTDHFAEVMPEDLIKYGL
MAB_1583|M.abscessus_ATCC_1997 GAFAGLEKIVSDRVGKRGLGFGAEVKSKADIDTTDHFAEVMPEDLIKFGL
******::*: :*:***********:**::*** ****:********:**
Mflv_2591|M.gilvum_PYR-GCK IPEFIGRLPVVASVTNLDKESLVKILSEPKNALVKQYTRLFEMDGVELEF
Mvan_4036|M.vanbaalenii_PYR-1 IPEFIGRLPVVASVTNLDKESLVQILSQPKNALVKQYTRLFEMDGVELEF
Rv2457c|M.tuberculosis_H37Rv IPEFIGRLPVVASVTNLDKESLVKILSEPKNALVKQYIRLFEMDGVELEF
Mb2484c|M.bovis_AF2122/97 IPEFIGRLPVVASVTNLDKESLVKILSEPKNALVKQYIRLFEMDGVELEF
MLBr_01477|M.leprae_Br4923 IPEFIGRLPVIASVINLDMESLVKILSEPKNALVKQYTWLFEMDGVELEF
MAV_1716|M.avium_104 IPEFIGRLPVVASVTNLDRESLVKILSEPKNALVKQYTRLFEMDGVELEF
MMAR_3805|M.marinum_M IPEFIGRLPVVASVTNLDKESLVKILSEPKNALVKQYTRLFEMDGVELEF
MUL_3728|M.ulcerans_Agy99 IPEFIGRLPVVASVTNLDKESLVKILSEPKNALVKQYTRLFEMDGVELEF
MSMEG_4671|M.smegmatis_MC2_155 IPEFIGRLPVVASVTNLDKASLVKILSEPKNALVKQYVRLFEMDGVELEF
TH_0353|M.thermoresistible__bu IPEFIGRLPVVASVTNLDKNSLVQILSKPKNALVKQYTKLFEMDGVELEF
MAB_1583|M.abscessus_ATCC_1997 IPEFIGRLPIVASVTNLDRESLIKILSEPKNALVKQYTRLFEMDGVELEF
*********::*** *** **::***:********* ***********
Mflv_2591|M.gilvum_PYR-GCK AEDALEAIADQAIHRGTGARGLRAIMEEVLLPVMYDIPSRDDVAKVVVTK
Mvan_4036|M.vanbaalenii_PYR-1 AEDALEAIADQAIHRGTGARGLRAIMEEVLLPVMYDIPSRDDVAKVVVTK
Rv2457c|M.tuberculosis_H37Rv TDDALEAIADQAIHRGTGARGLRAIMEEVLLPVMYDIPSRDDVAKVVVTK
Mb2484c|M.bovis_AF2122/97 TDDALEAIADQAIHRGTGARGLRAIMEEVLLPVMYDIPSRDDVAKVVVTK
MLBr_01477|M.leprae_Br4923 TNDALEAVADQAIHRGTGARGLRAIMEEVLLPVMYDIPSRDDVAKVVVTK
MAV_1716|M.avium_104 TDDALEAIADQAIHRGTGARGLRAIMEEVLLPVMYDIPSRDDVAKVVVTK
MMAR_3805|M.marinum_M TDDALEAIADQAIHRGTGARGLRAIMEEVLLPVMYDIPSRDDVAKVVVTK
MUL_3728|M.ulcerans_Agy99 TDDALEAIADQAIHRGTGARGLRAIMEEVLLPVMYDIPSRDDVAKVVVTK
MSMEG_4671|M.smegmatis_MC2_155 TEEALEAIADQAIHRGTGARGLRAIMEEVLLPVMYDIPSRDDVAKVVVTK
TH_0353|M.thermoresistible__bu TDDALEAIADQAIHRGTGARGLRAIMEEVLLPVMYDIPSRDDVAKVVVTK
MAB_1583|M.abscessus_ATCC_1997 SQDALEAIADQAIHRGTGARGLRAIMEEVLQPVMYDIPSRDDVAKVVVTG
:::****:********************** ******************
Mflv_2591|M.gilvum_PYR-GCK ETVDDNVLPTIVPRKPSRSERRDKTA
Mvan_4036|M.vanbaalenii_PYR-1 ETVLDNVLPTIVPRKPSRTERRDKSA
Rv2457c|M.tuberculosis_H37Rv ETVQDNVLPTIVPRKPSRSERRDKSA
Mb2484c|M.bovis_AF2122/97 ETVQDNVLPTIVPRKPSRSERRDKSA
MLBr_01477|M.leprae_Br4923 ETVQDNVLPTIVPRKPSRTERRDKSA
MAV_1716|M.avium_104 ETVQDNVLPTIVPRKPSRTERRDKSA
MMAR_3805|M.marinum_M ETVQDNVLPTIVPRKPSRSERRDKSA
MUL_3728|M.ulcerans_Agy99 ETVQDNVLPTIVPRKPSRSERRDKSA
MSMEG_4671|M.smegmatis_MC2_155 ETVQDNVLPTIVPRKPSRSERRDKSA
TH_0353|M.thermoresistible__bu ETVLDNVLPTIVPRKPSRAERRDKTA
MAB_1583|M.abscessus_ATCC_1997 ETVIDNVLPTIVPRKPSRTERRDKSA
*** **************:*****:*