For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
ARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEELADADDVKLDELPKPVEIREFL EGYVIGQDTAKRTLAVAVYNHYKRIQAGEKSHDSRCEAVELTKSNILMLGPTGCGKTYLAQTLAKMLNVP FAIADATALTEAGYVGEDVENILLKLIQAADYDVKRAETGIIYIDEVDKIARKSENPSITRDVSGEGVQQ ALLKILEGTQASVPPQGGRKHPHQEFIQIDTTNVLFIVAGAFAGLEKIIYERVGKRGLGFGAEVRSKAEI DTTDHFAEVMPEDLIKFGLIPEFIGRLPVVASVTNLDKESLVKILSEPKNALVKQYTRLFEMDGVELEFT DDALEAIADQAIHRGTGARGLRAIMEEVLLPVMYDIPSRDDVAKVVVTKETVQDNVLPTIVPRKPSRSER RDKSA*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. ulcerans Agy99 | MUL_3728 | clpX | - | 100% (426) | ATP-dependent protease ATP-binding subunit ClpX |
M. ulcerans Agy99 | MUL_1716 | ruvB | 6e-05 | 26.76% (142) | Holliday junction DNA helicase RuvB |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2484c | clpX | 0.0 | 98.59% (426) | ATP-dependent protease ATP-binding subunit ClpX |
M. gilvum PYR-GCK | Mflv_2591 | clpX | 0.0 | 96.24% (426) | ATP-dependent protease ATP-binding subunit |
M. tuberculosis H37Rv | Rv2457c | clpX | 0.0 | 98.59% (426) | ATP-dependent protease ATP-binding subunit ClpX |
M. leprae Br4923 | MLBr_01477 | clpX | 0.0 | 95.54% (426) | ATP-dependent protease ATP-binding subunit ClpX |
M. abscessus ATCC 19977 | MAB_1583 | clpX | 0.0 | 94.13% (426) | ATP-dependent protease ATP-binding subunit ClpX |
M. marinum M | MMAR_3805 | clpX | 0.0 | 99.77% (426) | ATP-dependent Clp protease ATP-binding subunit ClpX |
M. avium 104 | MAV_1716 | clpX | 0.0 | 98.36% (426) | ATP-dependent protease ATP-binding subunit |
M. smegmatis MC2 155 | MSMEG_4671 | clpX | 0.0 | 96.95% (426) | ATP-dependent protease ATP-binding subunit |
M. thermoresistible (build 8) | TH_0353 | clpX | 0.0 | 94.60% (426) | PROBABLE ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX |
M. vanbaalenii PYR-1 | Mvan_4036 | clpX | 0.0 | 95.77% (426) | ATP-dependent protease ATP-binding subunit |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_2591|M.gilvum_PYR-GCK MARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEEL Mvan_4036|M.vanbaalenii_PYR-1 MARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEEL MUL_3728|M.ulcerans_Agy99 MARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEEL MMAR_3805|M.marinum_M MARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEEL MLBr_01477|M.leprae_Br4923 MARIGDSGDLLKCSFCGKSQTQVKKLIAGPGVYICDECIDLCNEIIEEEL MAV_1716|M.avium_104 MARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEEL Mb2484c|M.bovis_AF2122/97 MARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEEL Rv2457c|M.tuberculosis_H37Rv MARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEEL MSMEG_4671|M.smegmatis_MC2_155 MARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEEL TH_0353|M.thermoresistible__bu MARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEEL MAB_1583|M.abscessus_ATCC_1997 MARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEEL ******.*************.***************************** Mflv_2591|M.gilvum_PYR-GCK ADADDVKLDELPKPAEIRDFLEGYVIGQDTAKRTLAVAVYNHYKRIQAGE Mvan_4036|M.vanbaalenii_PYR-1 ADADDVKLDELPKPAEIREFLEGYVIGQDTAKRTLAVAVYNHYKRIQAGE MUL_3728|M.ulcerans_Agy99 ADADDVKLDELPKPVEIREFLEGYVIGQDTAKRTLAVAVYNHYKRIQAGE MMAR_3805|M.marinum_M ADADDVKLDELPKPVEIREFLEGYVIGQDTAKRTLAVAVYNHYKRIQAGE MLBr_01477|M.leprae_Br4923 ADADDVQLDELPKPVEIREFLEGYVIGQDTAKRTLAVAVYNHYKRIQAGE MAV_1716|M.avium_104 ADADDVKLDELPKPIEIREFLEGYVIGQDTAKRTLAVAVYNHYKRIQAGE Mb2484c|M.bovis_AF2122/97 ADADDVKLDELPKPAEIREFLEGYVIGQDTAKRTLAVAVYNHYKRIQAGE Rv2457c|M.tuberculosis_H37Rv ADADDVKLDELPKPAEIREFLEGYVIGQDTAKRTLAVAVYNHYKRIQAGE MSMEG_4671|M.smegmatis_MC2_155 ADADDVKLDELPKPAEIREFLEGYVIGQDSAKRTLAVAVYNHYKRIQAGE TH_0353|M.thermoresistible__bu ADADEVKLDELPKPAEIHEFLESYVIGQESAKRTLAVAVYNHYKRIQAGE MAB_1583|M.abscessus_ATCC_1997 ADADDVKLDELPKPAEIRDFLENYVIGQDTAKKTLAVAVYNHYKRIQAGD ****:*:******* **::***.*****::**:****************: Mflv_2591|M.gilvum_PYR-GCK KARDSRAEPVELAKSNILMLGPTGCGKTYLAQTLAKMLNVPFAIADATAL Mvan_4036|M.vanbaalenii_PYR-1 KARDSRSEPVELAKSNILMLGPTGCGKTYLAQTLAKMLNVPFAIADATAL MUL_3728|M.ulcerans_Agy99 KSHDSRCEAVELTKSNILMLGPTGCGKTYLAQTLAKMLNVPFAIADATAL MMAR_3805|M.marinum_M KSRDSRCEAVELTKSNILMLGPTGCGKTYLAQTLAKMLNVPFAIADATAL MLBr_01477|M.leprae_Br4923 KGRDSKREPVELAKSNILMLGPTGCGKTYLAQTLAKMLNVPFAIADATAL MAV_1716|M.avium_104 KGRDSRHEPVELTKSNILMLGPTGCGKTYLAQTLAKMLNVPFAIADATAL Mb2484c|M.bovis_AF2122/97 KGRDSRCEPVELTKSNILMLGPTGCGKTYLAQTLAKMLNVPFAIADATAL Rv2457c|M.tuberculosis_H37Rv KGRDSRCEPVELTKSNILMLGPTGCGKTYLAQTLAKMLNVPFAIADATAL MSMEG_4671|M.smegmatis_MC2_155 KSRDSRSEPVELTKSNILMLGPTGCGKTYLAQTLAKMLNVPFAIADATAL TH_0353|M.thermoresistible__bu KSRDSRSEPVELAKSNILMLGPTGCGKTYLAQTLAKMLNVPFAIADATAL MAB_1583|M.abscessus_ATCC_1997 KARDARGETVELAKSNILMLGPTGCGKTYLAQTLAKMLNVPFAIADATAL *.:*:: *.***:************************************* Mflv_2591|M.gilvum_PYR-GCK TEAGYVGEDVENILLKLIQAADYDVKRAETGIIYIDEVDKIARKSENPSI Mvan_4036|M.vanbaalenii_PYR-1 TEAGYVGEDVENILLKLIQAADYDVKRAETGIIYIDEVDKIARKSENPSI MUL_3728|M.ulcerans_Agy99 TEAGYVGEDVENILLKLIQAADYDVKRAETGIIYIDEVDKIARKSENPSI MMAR_3805|M.marinum_M TEAGYVGEDVENILLKLIQAADYDVKRAETGIIYIDEVDKIARKSENPSI MLBr_01477|M.leprae_Br4923 TEAGYVGEDVENILLKLIQAADYDVKRAETGIIYIDEVDKIARKSENPSI MAV_1716|M.avium_104 TEAGYVGEDVENILLKLIQAADYDVKRAETGIIYIDEVDKIARKSENPSI Mb2484c|M.bovis_AF2122/97 TEAGYVGEDVENILLKLIQAADYDVKRAETGIIYIDEVDKIARKSENPSI Rv2457c|M.tuberculosis_H37Rv TEAGYVGEDVENILLKLIQAADYDVKRAETGIIYIDEVDKIARKSENPSI MSMEG_4671|M.smegmatis_MC2_155 TEAGYVGEDVENILLKLIQAADYDVKRAETGIIYIDEVDKIARKSENPSI TH_0353|M.thermoresistible__bu TEAGYVGEDVENILLKLIQAADYDVKRAETGIIYIDEVDKIARKSENPSI MAB_1583|M.abscessus_ATCC_1997 TEAGYVGEDVENILLKLIQAADYDVKRAETGIIYIDEVDKIARKSENPSI ************************************************** Mflv_2591|M.gilvum_PYR-GCK TRDVSGEGVQQALLKILEGTQASVPPQGGRKHPHQEFIQIDTTNVLFIVA Mvan_4036|M.vanbaalenii_PYR-1 TRDVSGEGVQQALLKILEGTQASVPPQGGRKHPHQEFIQIDTTNVLFIVA MUL_3728|M.ulcerans_Agy99 TRDVSGEGVQQALLKILEGTQASVPPQGGRKHPHQEFIQIDTTNVLFIVA MMAR_3805|M.marinum_M TRDVSGEGVQQALLKILEGTQASVPPQGGRKHPHQEFIQIDTTNVLFIVA MLBr_01477|M.leprae_Br4923 TRDVSGEGVQQALLKILEGTQASVPPQGGRKHPHQEFIQIDTTNVLFIVA MAV_1716|M.avium_104 TRDVSGEGVQQALLKILEGTQASVPPQGGRKHPHQEFIQIDTTNVLFIVA Mb2484c|M.bovis_AF2122/97 TRDVSGEGVQQALLKILEGTQASVPPQGGRKHPHQEFIQIDTTNVLFIVA Rv2457c|M.tuberculosis_H37Rv TRDVSGEGVQQALLKILEGTQASVPPQGGRKHPHQEFIQIDTTNVLFIVA MSMEG_4671|M.smegmatis_MC2_155 TRDVSGEGVQQALLKILEGTQASVPPQGGRKHPHQEFIQIDTTNVLFIVA TH_0353|M.thermoresistible__bu TRDVSGEGVQQALLKILEGTQASVPPQGGRKHPHQEFIQIDTTNVLFIVA MAB_1583|M.abscessus_ATCC_1997 TRDVSGEGVQQALLKILEGTQASVPPQGGRKHPHQEFIQIDTTNVLFIVA ************************************************** Mflv_2591|M.gilvum_PYR-GCK GAFAGLEKIVSDRVGKRGLGFGAEVHSKAEIDTQDHFAEVMPEDLIKFGL Mvan_4036|M.vanbaalenii_PYR-1 GAFAGLERIVSDRVGKRGLGFGAEVKSKAEIDTQDHFAEVMPEDLIKFGL MUL_3728|M.ulcerans_Agy99 GAFAGLEKIIYERVGKRGLGFGAEVRSKAEIDTTDHFAEVMPEDLIKFGL MMAR_3805|M.marinum_M GAFAGLEKIIYERVGKRGLGFGAEVRSKAEIDTTDHFAEVMPEDLIKFGL MLBr_01477|M.leprae_Br4923 GAFAGLDKIIYERIGKRGLGFGAEVRSKAEIDTTDHFADVMPEDLIKFGL MAV_1716|M.avium_104 GAFAGLEKIIYERVGKRGLGFGAEVRSKAEIDTTDHFAEVMPEDLIKFGL Mb2484c|M.bovis_AF2122/97 GAFAGLEKIIYERVGKRGLGFGAEVRSKAEIDTTDHFADVMPEDLIKFGL Rv2457c|M.tuberculosis_H37Rv GAFAGLEKIIYERVGKRGLGFGAEVRSKAEIDTTDHFADVMPEDLIKFGL MSMEG_4671|M.smegmatis_MC2_155 GAFAGLEKIVSDRVGKRGLGFGAEVRSKAEIDTQDHFAEVMPEDLIKFGL TH_0353|M.thermoresistible__bu GAFAGLEKIVQDRVGKRGLGFGAEVHSKSEIDTTDHFAEVMPEDLIKYGL MAB_1583|M.abscessus_ATCC_1997 GAFAGLEKIVSDRVGKRGLGFGAEVKSKADIDTTDHFAEVMPEDLIKFGL ******::*: :*:***********:**::*** ****:********:** Mflv_2591|M.gilvum_PYR-GCK IPEFIGRLPVVASVTNLDKESLVKILSEPKNALVKQYTRLFEMDGVELEF Mvan_4036|M.vanbaalenii_PYR-1 IPEFIGRLPVVASVTNLDKESLVQILSQPKNALVKQYTRLFEMDGVELEF MUL_3728|M.ulcerans_Agy99 IPEFIGRLPVVASVTNLDKESLVKILSEPKNALVKQYTRLFEMDGVELEF MMAR_3805|M.marinum_M IPEFIGRLPVVASVTNLDKESLVKILSEPKNALVKQYTRLFEMDGVELEF MLBr_01477|M.leprae_Br4923 IPEFIGRLPVIASVINLDMESLVKILSEPKNALVKQYTWLFEMDGVELEF MAV_1716|M.avium_104 IPEFIGRLPVVASVTNLDRESLVKILSEPKNALVKQYTRLFEMDGVELEF Mb2484c|M.bovis_AF2122/97 IPEFIGRLPVVASVTNLDKESLVKILSEPKNALVKQYIRLFEMDGVELEF Rv2457c|M.tuberculosis_H37Rv IPEFIGRLPVVASVTNLDKESLVKILSEPKNALVKQYIRLFEMDGVELEF MSMEG_4671|M.smegmatis_MC2_155 IPEFIGRLPVVASVTNLDKASLVKILSEPKNALVKQYVRLFEMDGVELEF TH_0353|M.thermoresistible__bu IPEFIGRLPVVASVTNLDKNSLVQILSKPKNALVKQYTKLFEMDGVELEF MAB_1583|M.abscessus_ATCC_1997 IPEFIGRLPIVASVTNLDRESLIKILSEPKNALVKQYTRLFEMDGVELEF *********::*** *** **::***:********* *********** Mflv_2591|M.gilvum_PYR-GCK AEDALEAIADQAIHRGTGARGLRAIMEEVLLPVMYDIPSRDDVAKVVVTK Mvan_4036|M.vanbaalenii_PYR-1 AEDALEAIADQAIHRGTGARGLRAIMEEVLLPVMYDIPSRDDVAKVVVTK MUL_3728|M.ulcerans_Agy99 TDDALEAIADQAIHRGTGARGLRAIMEEVLLPVMYDIPSRDDVAKVVVTK MMAR_3805|M.marinum_M TDDALEAIADQAIHRGTGARGLRAIMEEVLLPVMYDIPSRDDVAKVVVTK MLBr_01477|M.leprae_Br4923 TNDALEAVADQAIHRGTGARGLRAIMEEVLLPVMYDIPSRDDVAKVVVTK MAV_1716|M.avium_104 TDDALEAIADQAIHRGTGARGLRAIMEEVLLPVMYDIPSRDDVAKVVVTK Mb2484c|M.bovis_AF2122/97 TDDALEAIADQAIHRGTGARGLRAIMEEVLLPVMYDIPSRDDVAKVVVTK Rv2457c|M.tuberculosis_H37Rv TDDALEAIADQAIHRGTGARGLRAIMEEVLLPVMYDIPSRDDVAKVVVTK MSMEG_4671|M.smegmatis_MC2_155 TEEALEAIADQAIHRGTGARGLRAIMEEVLLPVMYDIPSRDDVAKVVVTK TH_0353|M.thermoresistible__bu TDDALEAIADQAIHRGTGARGLRAIMEEVLLPVMYDIPSRDDVAKVVVTK MAB_1583|M.abscessus_ATCC_1997 SQDALEAIADQAIHRGTGARGLRAIMEEVLQPVMYDIPSRDDVAKVVVTG :::****:********************** ****************** Mflv_2591|M.gilvum_PYR-GCK ETVDDNVLPTIVPRKPSRSERRDKTA Mvan_4036|M.vanbaalenii_PYR-1 ETVLDNVLPTIVPRKPSRTERRDKSA MUL_3728|M.ulcerans_Agy99 ETVQDNVLPTIVPRKPSRSERRDKSA MMAR_3805|M.marinum_M ETVQDNVLPTIVPRKPSRSERRDKSA MLBr_01477|M.leprae_Br4923 ETVQDNVLPTIVPRKPSRTERRDKSA MAV_1716|M.avium_104 ETVQDNVLPTIVPRKPSRTERRDKSA Mb2484c|M.bovis_AF2122/97 ETVQDNVLPTIVPRKPSRSERRDKSA Rv2457c|M.tuberculosis_H37Rv ETVQDNVLPTIVPRKPSRSERRDKSA MSMEG_4671|M.smegmatis_MC2_155 ETVQDNVLPTIVPRKPSRSERRDKSA TH_0353|M.thermoresistible__bu ETVLDNVLPTIVPRKPSRAERRDKTA MAB_1583|M.abscessus_ATCC_1997 ETVIDNVLPTIVPRKPSRTERRDKSA *** **************:*****:*