For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VQARGQVLITAAELAGMIQAGDPVSILDVRWRLDEPDGHAAYLQGHLPGAVFVSLEDELSDHTIAGRGRH PLPSGASLQATVRRCGIRHDVPVVVYDDWNRAGSARAWWVLTAAGIANVRILDGGLPAWRSAGGSIETGQ VSPQLGNVTVLHDDLYAGQRLTLTAQQAGAGGVTLLDARVPERFRGDVEPVDAVAGHIPGAINVPSGSVL ADDGTFLGNGALNALLSDHGIDHGGRVGVYCGSGVSAAVIVAALAVIGQDAELFPGSWSEWSSDPTRPVG RGTA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2291 | sseB | - | 100% (284) | Probable thiosulfate sulfurtransferase SseB |
| M. tuberculosis H37Rv | Rv3117 | cysA3 | 8e-18 | 26.48% (253) | thiosulfate sulfurtransferase CysA3 |
| M. tuberculosis H37Rv | Rv0815c | cysA2 | 8e-18 | 26.48% (253) | thiosulfate sulfurtransferase CysA2 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2314 | sseB | 1e-149 | 99.22% (256) | thiosulfate sulfurtransferase SseB |
| M. gilvum PYR-GCK | Mflv_1452 | - | 4e-97 | 62.50% (280) | 3-mercaptopyruvate sulfurtransferase |
| M. leprae Br4923 | MLBr_02198 | cysA3 | 3e-14 | 28.37% (208) | thiosulfate sulfurtransferase |
| M. abscessus ATCC 19977 | MAB_0071c | - | 1e-72 | 50.36% (276) | putative thiosulfate sulfurtransferase (SseB) |
| M. marinum M | MMAR_2918 | - | 1e-117 | 70.67% (283) | thiosulfate sulfotransferase |
| M. avium 104 | MAV_2142 | - | 1e-117 | 70.42% (284) | thiosulfate sulfurtransferase |
| M. smegmatis MC2 155 | MSMEG_3238 | - | 1e-101 | 62.99% (281) | 3-mercaptopyruvate sulfurtransferase |
| M. thermoresistible (build 8) | TH_2323 | sseB | 2e-95 | 63.08% (279) | Probable thiosulfate sulfurtransferase SseB |
| M. ulcerans Agy99 | MUL_0432 | cysA2 | 1e-18 | 26.99% (289) | thiosulfate sulfurtransferase, CysA2 |
| M. vanbaalenii PYR-1 | Mvan_5322 | - | 5e-96 | 62.01% (279) | 3-mercaptopyruvate sulfurtransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Rv2291|M.tuberculosis_H37Rv -MQARGQVLITAAELAGMIQAGDPVSILDVRWRLDEPDGHAAYLQGHLPG
Mb2314|M.bovis_AF2122/97 -----------------------------MRWRLDEPDGHAAYLQGHLPG
MMAR_2918|M.marinum_M -MQARGQVLISVAELTDHIRAGLPVTILDVRWQLGEPDGHPSYLRGHLPG
MAV_2142|M.avium_104 -MGARDQVLITATELADVIEAGDPVSILDVRWRLDEPDGRAAYLQGHLPG
MSMEG_3238|M.smegmatis_MC2_155 MATTRSDVFISTAELIQLLAAGGPVTLLDVRWTLAEPNGEQAYLDGHLPG
TH_2323|M.thermoresistible__bu -MTDRDRVLISAGEVARLLDSGRPVTLLDVRWELTRPHGRAAYEQGHLPG
Mflv_1452|M.gilvum_PYR-GCK --MSRADVFVTATDLSRMIAEDRPVSVLDVRWRLDAPDGRQAYAQGHVPG
Mvan_5322|M.vanbaalenii_PYR-1 --MTRADIFITAAELARLIAEGAPVNVLDVRWELTRPDGREAYTRGHVPG
MAB_0071c|M.abscessus_ATCC_199 -----MDVLISPSELADRLTD---FRLLDVRWTVMAPDGRAAYLAGHLPG
MLBr_02198|M.leprae_Br4923 --MARSDVLVSADWAESNLDS---ANIVFVEVDEDTS----TYDGDHIAG
MUL_0432|M.ulcerans_Agy99 --MARTDVLVSADWAKSNLGNSEAANVVFVEVDEDAS----AYDDGHIAG
:. . :* .*:.*
Rv2291|M.tuberculosis_H37Rv AVFVSLEDELSDHTIAGRGRHPLPSGASLQATVRRCGIRHDVPVVVYDDW
Mb2314|M.bovis_AF2122/97 AVFVSLEDELSDHTIAGRGRHPLPSGASLQATVRRCGIRHDVPVVVYDDW
MMAR_2918|M.marinum_M AVYVSLEAELSDHTVAGRGRHPLPSGRNLEIAARRWGVQQDELVVVYDDW
MAV_2142|M.avium_104 AVYVSLEDELSDHTVSGRGRHPLPSGPSLQAAARRWGIRQDTPVVVYDDW
MSMEG_3238|M.smegmatis_MC2_155 AVYVSLDDELADHTVRGRGRHPLPSGRHLEAAARRWGVRDGVPTVVYDDW
TH_2323|M.thermoresistible__bu AVYVSLENELSDHRVPGRGRHPLPSGPDLQAAARRWGVRAGVPVVVYDDW
Mflv_1452|M.gilvum_PYR-GCK AVYVSLDDELSDHSVPDRGRHPLPSGVALQAAARRWGLREGVPTVVYDDW
Mvan_5322|M.vanbaalenii_PYR-1 AVYVSLEDELSDHAVTGRGRHPLPSGDSVESAARRWGLRRGVPTVVYDDW
MAB_0071c|M.abscessus_ATCC_199 AVFVDLDVDLADHSVTGRGRHPLPTPQALAASARRWGLNDGDAVVVYDDW
MLBr_02198|M.leprae_Br4923 AIKLDWRADLQDPIKR-----DFIDTQQFSKLLGDRGISNDNTVILYGGN
MUL_0432|M.ulcerans_Agy99 AIKLDWRTDLQDPIKR-----DFVDAQQFSKLLSDRGISNDDTVVLYGGN
*: :. :* * : . *: . .::*..
Rv2291|M.tuberculosis_H37Rv NRAGSARAWWVLTAAGIANVRILDGGLPAWRSAGGSIETGQVSPQLGNVT
Mb2314|M.bovis_AF2122/97 NRAGSARAWWVLTAAGIANVRILDGGLPAWRSAGGSIETGQVSPQLGNVT
MMAR_2918|M.marinum_M NRAGSARAWWLLTTAGVANVRILDGGLGAWRRAGGHLQTGAVHPRAGNVS
MAV_2142|M.avium_104 NRAGSARAWWLLRAAGLDNVRILDGGLAAWRAAGGRLVSGPVEPAPGNVT
MSMEG_3238|M.smegmatis_MC2_155 NRAGSARAWWCLTAAGISGVRILDGGLGAWVAGGGGVETGPVTPEPGDVR
TH_2323|M.thermoresistible__bu NGAGSARAWWVLTAAGIDDVRILDGGLSAWTG---ELHTGPVDPEPGEVT
Mflv_1452|M.gilvum_PYR-GCK NRAGSARAWWVLRAAGIEDVRILDGGLAAWAAAGGDLEAGEVSRPPGDVV
Mvan_5322|M.vanbaalenii_PYR-1 NRAGSARAWWVLTAAGIGGVRILDGGLAAWTAAGGRLETGVPAIDPGDVA
MAB_0071c|M.abscessus_ATCC_199 NGQAAARAWWLLRAAGVSNVRILDGGWAAWQRSGGPVATEEVVPVVGDIT
MLBr_02198|M.leprae_Br4923 NNWFAAYAYWYFKLYRHDKVKLLDGGRKKWELDGRPLSTDTVTRPATSYA
MUL_0432|M.ulcerans_Agy99 NNWFAAYAYWYFKLYGHQNVKLLDGGRKKWELDGRPLSTAAVSRPATSYT
* :* *:* : *::**** * : : .
Rv2291|M.tuberculosis_H37Rv VLHDDLYAGQRLTLTAQQAGAGGVTLLDARVPERFRGDVEP-------VD
Mb2314|M.bovis_AF2122/97 VLHDDLYAGQRLTLTAQQAGAGGVTLLDARVPERFRGDVEP-------VD
MMAR_2918|M.marinum_M VLHEDLYVGSRPTLTASQVGAGVTTLLDARAPERFRGDVEP-------ID
MAV_2142|M.avium_104 VPHDDLHSGNRPTVTTEQVTAGAATLIDARAPERYRGEMEP-------LD
MSMEG_3238|M.smegmatis_MC2_155 VVHDDLYRGALPTLTADDVQSAA-ALIDARAPERFRGEVEP-------VD
TH_2323|M.thermoresistible__bu VRYHDLYSGARRTVTADRVSGVA-VLLDARAPERFRGEREP-------VD
Mflv_1452|M.gilvum_PYR-GCK VRCADLYRGALPTLTVDEVAEFDGLLLDARAPERFRGDTEP-------VD
Mvan_5322|M.vanbaalenii_PYR-1 VEFRDLYRGALPALTAEDVTGFDGVLLDARAPERFRGDTEP-------VD
MAB_0071c|M.abscessus_ATCC_199 ITSLHGLAAVDADAVAAQAQSPDNLVFDARAAARYRGDEEP-------LD
MLBr_02198|M.leprae_Br4923 AAAPDNTIRAFRDEVIASIKIKN--LVDVRSPDEFSGKLLAPAHLPQEQS
MUL_0432|M.ulcerans_Agy99 AVAPDNSIRAFRDEVIAAIHVKN--LVDVRSPDEFSGKILAPAHLPQEQS
. . :.*.* . .: *. . .
Rv2291|M.tuberculosis_H37Rv AVAGHIPGAINVPSGSVLADDGTFLGNGALNALLSDHGIDH--GGRVGVY
Mb2314|M.bovis_AF2122/97 AVAGHIPGAINVPSGSVLADDGTFLGNGALNALLSDHGIDH--GGRVGVY
MMAR_2918|M.marinum_M PVGGHIPGAKNLPSGAVLTADGTFVDTGALDELLSGCGIDR--DGAMGAY
MAV_2142|M.avium_104 PVAGHIPGAENLPSGDVLAADGTFLDDDALARVFAEHRIER--HGAVAAY
MSMEG_3238|M.smegmatis_MC2_155 PVAGHVPGAVNLPSTGLLNPDGTLRDEAQVRALLADRGVDDTGDTAVGAY
TH_2323|M.thermoresistible__bu PVAGHIPGAVNLPSTSLLAG-GRFRDHDELRRLVRDLAIDP--ETDVAAY
Mflv_1452|M.gilvum_PYR-GCK PVAGHIPGATNAPSTGVLDGDGVLLPTEELVAFAERVGADG--DSAVGVY
Mvan_5322|M.vanbaalenii_PYR-1 RVAGHIPGARNAPSVETLSVDGTFLPDDELVRYFRGRGAT---EGGVGVY
MAB_0071c|M.abscessus_ATCC_199 PRAGHIPGAVSAPTAENLTADGTFKPVAELRERFDKLGAGA---APVTVY
MLBr_02198|M.leprae_Br4923 QRPGHIPSAINIPWSKAANEDGTFKSDEQLAKLYADAGLDR--LKETIVY
MUL_0432|M.ulcerans_Agy99 QRPGHVPGAINVPWSRTANEDGTFRTDEQLAKLYADAGLDG--AKETIAY
**:*.* . * * : : .*
Rv2291|M.tuberculosis_H37Rv CGSGVSAAVIVAALAVIG--QDAELFPGSWSEWSSDPTRPVGRGTA----
Mb2314|M.bovis_AF2122/97 CGSGVSAAVIVAALAVIG--QDAALFPGSWSEWSSDPTRPVGRGTA----
MMAR_2918|M.marinum_M CGSGITAAVTVAALVAAG--GDAALYPGSWSEWCSDPNRPVERSTE----
MAV_2142|M.avium_104 CGSGVTATVTIAALAAVG--RTAALYPGSWSEWCADPARPVERGGA----
MSMEG_3238|M.smegmatis_MC2_155 CGSGVTAALTVAGLAAAG--VDAALFPGSWSEWVCDPGRPVARGEK----
TH_2323|M.thermoresistible__bu CGSGVTAAVVVAALASVG--VDAALFPGSWSQWCSEPGRPVEVGAGQGRS
Mflv_1452|M.gilvum_PYR-GCK CGSGVTAAVTVAALMATG--VPARLFPGSWSQWSADPSRPVATGH-----
Mvan_5322|M.vanbaalenii_PYR-1 CGSGVTAAVTIAALRATG--VEAKLFPGSWSQWSADASRPVATGE-----
MAB_0071c|M.abscessus_ATCC_199 CGSGVTATHQIAALAIAG--YDAALYPGSWSEWSSDPQRPVATGPNPA--
MLBr_02198|M.leprae_Br4923 CRIGERSSHTWFVLRELLGYQNVKNYDGSWTEYGSLVGVPIELGS-----
MUL_0432|M.ulcerans_Agy99 CRIGERSSHTWFVLHELLGHKNVKNYDGSWTEYGSLVGAPIELGN-----
* * :: * . : ***::: . *: .
Rv2291|M.tuberculosis_H37Rv -
Mb2314|M.bovis_AF2122/97 -
MMAR_2918|M.marinum_M -
MAV_2142|M.avium_104 -
MSMEG_3238|M.smegmatis_MC2_155 -
TH_2323|M.thermoresistible__bu R
Mflv_1452|M.gilvum_PYR-GCK -
Mvan_5322|M.vanbaalenii_PYR-1 -
MAB_0071c|M.abscessus_ATCC_199 -
MLBr_02198|M.leprae_Br4923 -
MUL_0432|M.ulcerans_Agy99 -