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VSRADVFVTATDLSRMIAEDRPVSVLDVRWRLDAPDGRQAYAQGHVPGAVYVSLDDELSDHSVPDRGRHP LPSGVALQAAARRWGLREGVPTVVYDDWNRAGSARAWWVLRAAGIEDVRILDGGLAAWAAAGGDLEAGEV SRPPGDVVVRCADLYRGALPTLTVDEVAEFDGLLLDARAPERFRGDTEPVDPVAGHIPGATNAPSTGVLD GDGVLLPTEELVAFAERVGADGDSAVGVYCGSGVTAAVTVAALMATGVPARLFPGSWSQWSADPSRPVAT GH
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1452 | - | - | 100% (282) | 3-mercaptopyruvate sulfurtransferase |
| M. gilvum PYR-GCK | Mflv_1646 | - | 1e-16 | 24.91% (293) | thiosulfate sulfurtransferase |
| M. gilvum PYR-GCK | Mflv_4780 | - | 2e-14 | 27.67% (253) | rhodanese domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2314 | sseB | 6e-90 | 63.78% (254) | thiosulfate sulfurtransferase SseB |
| M. tuberculosis H37Rv | Rv2291 | sseB | 3e-97 | 62.50% (280) | thiosulfate sulfurtransferase SseB |
| M. leprae Br4923 | MLBr_00728 | sseA | 5e-14 | 28.85% (253) | putative thiosulfate sulfurtransferase |
| M. abscessus ATCC 19977 | MAB_0071c | - | 4e-77 | 51.62% (277) | putative thiosulfate sulfurtransferase (SseB) |
| M. marinum M | MMAR_2918 | - | 4e-92 | 58.48% (277) | thiosulfate sulfotransferase |
| M. avium 104 | MAV_2142 | - | 1e-100 | 62.50% (280) | thiosulfate sulfurtransferase |
| M. smegmatis MC2 155 | MSMEG_3238 | - | 1e-105 | 65.60% (282) | 3-mercaptopyruvate sulfurtransferase |
| M. thermoresistible (build 8) | TH_2323 | sseB | 3e-96 | 62.72% (279) | Probable thiosulfate sulfurtransferase SseB |
| M. ulcerans Agy99 | MUL_0432 | cysA2 | 2e-16 | 25.25% (297) | thiosulfate sulfurtransferase, CysA2 |
| M. vanbaalenii PYR-1 | Mvan_5322 | - | 1e-118 | 73.31% (281) | 3-mercaptopyruvate sulfurtransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2314|M.bovis_AF2122/97 ----------------------------------------MRWRLDEPDG
Rv2291|M.tuberculosis_H37Rv ------------MQARGQVLITAAELAGMIQAGDPVSILDVRWRLDEPDG
MMAR_2918|M.marinum_M ------------MQARGQVLISVAELTDHIRAGLPVTILDVRWQLGEPDG
MAV_2142|M.avium_104 ------------MGARDQVLITATELADVIEAGDPVSILDVRWRLDEPDG
Mflv_1452|M.gilvum_PYR-GCK -------------MSRADVFVTATDLSRMIAEDRPVSVLDVRWRLDAPDG
Mvan_5322|M.vanbaalenii_PYR-1 -------------MTRADIFITAAELARLIAEGAPVNVLDVRWELTRPDG
MSMEG_3238|M.smegmatis_MC2_155 -----------MATTRSDVFISTAELIQLLAAGGPVTLLDVRWTLAEPNG
TH_2323|M.thermoresistible__bu ------------MTDRDRVLISAGEVARLLDSGRPVTLLDVRWELTRPHG
MAB_0071c|M.abscessus_ATCC_199 ----------------MDVLISPSELADRLTD---FRLLDVRWTVMAPDG
MLBr_00728|M.leprae_Br4923 MPLPTDPSPSLSAYAHPERLVTGDWLYFHLGKP---GLAIVES----DEN
MUL_0432|M.ulcerans_Agy99 -------------MARTDVLVSADWAKSNLGNSEAANVVFVEV----DED
:. ..
Mb2314|M.bovis_AF2122/97 HAAYLQGHLPGAVFVSLEDELSDHTIAGRGRHPLPSGASLQATVRRCGIR
Rv2291|M.tuberculosis_H37Rv HAAYLQGHLPGAVFVSLEDELSDHTIAGRGRHPLPSGASLQATVRRCGIR
MMAR_2918|M.marinum_M HPSYLRGHLPGAVYVSLEAELSDHTVAGRGRHPLPSGRNLEIAARRWGVQ
MAV_2142|M.avium_104 RAAYLQGHLPGAVYVSLEDELSDHTVSGRGRHPLPSGPSLQAAARRWGIR
Mflv_1452|M.gilvum_PYR-GCK RQAYAQGHVPGAVYVSLDDELSDHSVPDRGRHPLPSGVALQAAARRWGLR
Mvan_5322|M.vanbaalenii_PYR-1 REAYTRGHVPGAVYVSLEDELSDHAVTGRGRHPLPSGDSVESAARRWGLR
MSMEG_3238|M.smegmatis_MC2_155 EQAYLDGHLPGAVYVSLDDELADHTVRGRGRHPLPSGRHLEAAARRWGVR
TH_2323|M.thermoresistible__bu RAAYEQGHLPGAVYVSLENELSDHRVPGRGRHPLPSGPDLQAAARRWGVR
MAB_0071c|M.abscessus_ATCC_199 RAAYLAGHLPGAVFVDLDVDLADHSVTGRGRHPLPTPQALAASARRWGLN
MLBr_00728|M.leprae_Br4923 VLLYDVGHIPGAVKVDWHTDLNDPKVR-----DYITGEQFADLMNRKGIA
MUL_0432|M.ulcerans_Agy99 ASAYDDGHIAGAIKLDWRTDLQDPIKR-----DFVDAQQFSKLLSDRGIS
* **:.**: :. :* * . *:
Mb2314|M.bovis_AF2122/97 HDVPVVVYDDWNRAGSARAWWVLTAAGIANVRILDGGLPAWRSAGGSIET
Rv2291|M.tuberculosis_H37Rv HDVPVVVYDDWNRAGSARAWWVLTAAGIANVRILDGGLPAWRSAGGSIET
MMAR_2918|M.marinum_M QDELVVVYDDWNRAGSARAWWLLTTAGVANVRILDGGLGAWRRAGGHLQT
MAV_2142|M.avium_104 QDTPVVVYDDWNRAGSARAWWLLRAAGLDNVRILDGGLAAWRAAGGRLVS
Mflv_1452|M.gilvum_PYR-GCK EGVPTVVYDDWNRAGSARAWWVLRAAGIEDVRILDGGLAAWAAAGGDLEA
Mvan_5322|M.vanbaalenii_PYR-1 RGVPTVVYDDWNRAGSARAWWVLTAAGIGGVRILDGGLAAWTAAGGRLET
MSMEG_3238|M.smegmatis_MC2_155 DGVPTVVYDDWNRAGSARAWWCLTAAGISGVRILDGGLGAWVAGGGGVET
TH_2323|M.thermoresistible__bu AGVPVVVYDDWNGAGSARAWWVLTAAGIDDVRILDGGLSAWTG---ELHT
MAB_0071c|M.abscessus_ATCC_199 DGDAVVVYDDWNGQAAARAWWLLRAAGVSNVRILDGGWAAWQRSGGPVAT
MLBr_00728|M.leprae_Br4923 RDDTVVIYGDKSNWWAAYALWVFTLFGHPDVRLLNGGRDLWLAERRDTSL
MUL_0432|M.ulcerans_Agy99 NDDTVVLYGGNNNWFAAYAYWYFKLYGHQNVKLLDGGRKKWELDGRPLST
. .*:*.. . :* * * : * .*::*:** *
Mb2314|M.bovis_AF2122/97 GQVSPQLGNVTVLHDDLYAGQRLTLTAQQAGAGGVTLLDARVPERFRGDV
Rv2291|M.tuberculosis_H37Rv GQVSPQLGNVTVLHDDLYAGQRLTLTAQQAGAGGVTLLDARVPERFRGDV
MMAR_2918|M.marinum_M GAVHPRAGNVSVLHEDLYVGSRPTLTASQVGAGVTTLLDARAPERFRGDV
MAV_2142|M.avium_104 GPVEPAPGNVTVPHDDLHSGNRPTVTTEQVTAGAATLIDARAPERYRGEM
Mflv_1452|M.gilvum_PYR-GCK GEVSRPPGDVVVRCADLYRGALPTLTVDEVAEFDGLLLDARAPERFRGDT
Mvan_5322|M.vanbaalenii_PYR-1 GVPAIDPGDVAVEFRDLYRGALPALTAEDVTGFDGVLLDARAPERFRGDT
MSMEG_3238|M.smegmatis_MC2_155 GPVTPEPGDVRVVHDDLYRGALPTLTADDVQSAA-ALIDARAPERFRGEV
TH_2323|M.thermoresistible__bu GPVDPEPGEVTVRYHDLYSGARRTVTADRVSGVA-VLLDARAPERFRGER
MAB_0071c|M.abscessus_ATCC_199 EEVVPVVGDITITSLHGLAAVDADAVAAQAQSPDNLVFDARAAARYRGDE
MLBr_00728|M.leprae_Br4923 AVPNKTSTSYPVVNRNDAP-IRAFKDDVLAILGTQPLIDVRSLDEYTGKC
MUL_0432|M.ulcerans_Agy99 AAVSRPATSYTAVAPDNS--IRAFRDEVIAAIHVKNLVDVRSPDEFSGKI
. . . :.*.* .: *.
Mb2314|M.bovis_AF2122/97 EPVDA-------VAGHIPGAINVPSGSVLADDGTFLGNGALNALLSDHGI
Rv2291|M.tuberculosis_H37Rv EPVDA-------VAGHIPGAINVPSGSVLADDGTFLGNGALNALLSDHGI
MMAR_2918|M.marinum_M EPIDP-------VGGHIPGAKNLPSGAVLTADGTFVDTGALDELLSGCGI
MAV_2142|M.avium_104 EPLDP-------VAGHIPGAENLPSGDVLAADGTFLDDDALARVFAEHRI
Mflv_1452|M.gilvum_PYR-GCK EPVDP-------VAGHIPGATNAPSTGVLDGDGVLLPTEELVAFAERVGA
Mvan_5322|M.vanbaalenii_PYR-1 EPVDR-------VAGHIPGARNAPSVETLSVDGTFLPDDELVRYFRGRGA
MSMEG_3238|M.smegmatis_MC2_155 EPVDP-------VAGHVPGAVNLPSTGLLNPDGTLRDEAQVRALLADRGV
TH_2323|M.thermoresistible__bu EPVDP-------VAGHIPGAVNLPSTSLLAG-GRFRDHDELRRLVRDLAI
MAB_0071c|M.abscessus_ATCC_199 EPLDP-------RAGHIPGAVSAPTAENLTADGTFKPVAELRERFDKLGA
MLBr_00728|M.leprae_Br4923 TEMPDSPEESVLRAGHIPTARSIPWEMTVDKSGRFRSSEELERLYDFITP
MUL_0432|M.ulcerans_Agy99 LAPAHLPQEQSQRPGHVPGAINVPWSRTANEDGTFRTDEQLAKLYADAGL
**:* * . * * : :
Mb2314|M.bovis_AF2122/97 DH--GGRVGVYCGSGVSAAVIVAALAVIG--QDAALFPGSWSEWSSDPTR
Rv2291|M.tuberculosis_H37Rv DH--GGRVGVYCGSGVSAAVIVAALAVIG--QDAELFPGSWSEWSSDPTR
MMAR_2918|M.marinum_M DR--DGAMGAYCGSGITAAVTVAALVAAG--GDAALYPGSWSEWCSDPNR
MAV_2142|M.avium_104 ER--HGAVAAYCGSGVTATVTIAALAAVG--RTAALYPGSWSEWCADPAR
Mflv_1452|M.gilvum_PYR-GCK DG--DSAVGVYCGSGVTAAVTVAALMATG--VPARLFPGSWSQWSADPSR
Mvan_5322|M.vanbaalenii_PYR-1 T---EGGVGVYCGSGVTAAVTIAALRATG--VEAKLFPGSWSQWSADASR
MSMEG_3238|M.smegmatis_MC2_155 DDTGDTAVGAYCGSGVTAALTVAGLAAAG--VDAALFPGSWSEWVCDPGR
TH_2323|M.thermoresistible__bu DP--ETDVAAYCGSGVTAAVVVAALASVG--VDAALFPGSWSQWCSEPGR
MAB_0071c|M.abscessus_ATCC_199 GA---APVTVYCGSGVTATHQIAALAIAG--YDAALYPGSWSEWSSDPQR
MLBr_00728|M.leprae_Br4923 N----DKTIVYCRIGERSSHTWFVLTHLLGKPGVRNYDGSWTEWGNTVRV
MUL_0432|M.ulcerans_Agy99 DG--AKETIAYCRIGERSSHTWFVLHELLGHKNVKNYDGSWTEYGSLVGA
.** * :: * . : ***:::
Mb2314|M.bovis_AF2122/97 PVGRGTA------
Rv2291|M.tuberculosis_H37Rv PVGRGTA------
MMAR_2918|M.marinum_M PVERSTE------
MAV_2142|M.avium_104 PVERGGA------
Mflv_1452|M.gilvum_PYR-GCK PVATGH-------
Mvan_5322|M.vanbaalenii_PYR-1 PVATGE-------
MSMEG_3238|M.smegmatis_MC2_155 PVARGEK------
TH_2323|M.thermoresistible__bu PVEVGAGQGRSR-
MAB_0071c|M.abscessus_ATCC_199 PVATGPNPA----
MLBr_00728|M.leprae_Br4923 PITAGESPGAVPV
MUL_0432|M.ulcerans_Agy99 PIELGN-------
*: .