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MSDNAKHHRDGHLVASGLQDRAARTPQHEGFLGPDRPWHLSFSLLLAGSFVLFSWWAFDYAGSGANKVIL VLATVVGMFMAFNVGGNDVANSFGTSVGAGTLTMKQALLVAAIFEVSGAVIAGGDVTETIRSGIVDLSGV SVDPRDFMNIMLSALSAAALWLLFANRMGYPVSTTHSIIGGIVGAAIALGMVSGQGGAALRMVQWDQIGQ IVVSWVLSPVLGGLVSYLLYGVIKRHILLYNEQAERRLTEIKKERIAHRERHKAAFDRLTEIQQIAYTGA LARDAVAANRKDFDPDELESDYYRELHEIDAKTSSVDAFRALQNWVPLVAAAGSMIIVAMLLFKGFKHMH LGLTTMNNYFIIAMVGAAVWMATFIFAKTLRGESLSRSTFLMFSWMQVFTASGFAFSHGSNDIANAIGPF AAILDVLRTGAIEGNAAVPAAAMVTFGVALCAGLWFIGRRVIATVGHNLTTMHPASGFAAELSAAGVVMG ATVLGLPVSSTHILIGAVLGVGIVNRSTNWGLMKPIVLAWVITLPSAAILASVGLVALRAIF
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2281 | pitB | - | 100% (552) | Putative phosphate-transport permease PitB |
| M. tuberculosis H37Rv | Rv0545c | pitA | 9e-20 | 32.97% (185) | inorganic phosphate transporter |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2302 | pitB | 0.0 | 100.00% (552) | phosphate ABC transporter permease |
| M. gilvum PYR-GCK | Mflv_0031 | - | 1e-20 | 33.97% (156) | phosphate transporter |
| M. leprae Br4923 | MLBr_02260 | pitA | 3e-17 | 30.43% (184) | low-affinity inorganic phosphate transporter |
| M. abscessus ATCC 19977 | MAB_3950c | - | 1e-21 | 33.97% (156) | inorganic phosphate transporter |
| M. marinum M | MMAR_3415 | pitB | 0.0 | 88.68% (539) | phosphate-transport permease PitB |
| M. avium 104 | MAV_4599 | - | 8e-17 | 30.65% (186) | phosphate transporter |
| M. smegmatis MC2 155 | MSMEG_1064 | - | 2e-18 | 32.24% (152) | phosphate/sulphate permease |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_2694 | pitB | 0.0 | 88.31% (539) | phosphate-transport permease PitB |
| M. vanbaalenii PYR-1 | Mvan_0939 | - | 4e-20 | 33.33% (156) | phosphate transporter |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0031|M.gilvum_PYR-GCK -------------------------------------MGSISHPPTPAKI
MSMEG_1064|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_0939|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3950c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_02260|M.leprae_Br4923 --------------------------------------------------
MAV_4599|M.avium_104 --------------------------------------------------
Rv2281|M.tuberculosis_H37Rv MSDNAKHHRDGHLVASGLQDRAARTPQHEGFLGPDRPWHLSFSLLLAGSF
Mb2302|M.bovis_AF2122/97 MSDNAKHHRDGHLVASGLQDRAARTPQHEGFLGPDRPWHLSFSLLLAGSF
MMAR_3415|M.marinum_M -------------MASGLQDPITPTPQYGGLFGQDRAWHLSFGLLLAGSF
MUL_2694|M.ulcerans_Agy99 -------------MASGLQDPITPTPQYGGLFGQDRAWHLSFGLLLAGSF
Mflv_0031|M.gilvum_PYR-GCK RKTGAEGRRINSMSAELVVLVLLIITALAFDFTNGFHDTGNAMATSIATG
MSMEG_1064|M.smegmatis_MC2_155 ------------MSAELVVLVLLIATALAFDFTNGFHDTGNAMATSIATR
Mvan_0939|M.vanbaalenii_PYR-1 ------------MSAELIILVLLIATALAFDFTNGFHDTGNAMATSIATG
MAB_3950c|M.abscessus_ATCC_199 ------------MDATMIILVLLIATALAFDFTNGFHDTGNAMATSIATG
MLBr_02260|M.leprae_Br4923 ------------MNINLFLLIIVVITALAFDFTNGFHDTGNAMATSIASG
MAV_4599|M.avium_104 ------------MNIQLFLLIIVVITALAFDFTNGFHDTGNAMATSIASG
Rv2281|M.tuberculosis_H37Rv VLFSWWAFDYAGSGANKVILVLATVVGMFMAFNVGGNDVANSFGTSVGAG
Mb2302|M.bovis_AF2122/97 VLFSWWAFDYAGSGANKVILVLATVVGMFMAFNVGGNDVANSFGTSVGAG
MMAR_3415|M.marinum_M VLFSFWAFDYAGPSANKLILVLATVVGMFMAFNVGGNDVANSFGTSVGAG
MUL_2694|M.ulcerans_Agy99 VLFSFWAFDYAGPGANKLILVLATVVGMFMAFNVGGNDVANSFGTSVGAG
. .:*:: ..: : *. * :*..*::.**:.:
Mflv_0031|M.gilvum_PYR-GCK ALKPKTAVLLAGILNLVGAFLS-VEVAVTVTTSVLKVQDSTSGELLSGID
MSMEG_1064|M.smegmatis_MC2_155 ALKPKTAVLLAGVLNLVGAFLS-VEVAITVTSSVLKIQDSSTGQLVGSID
Mvan_0939|M.vanbaalenii_PYR-1 ALKPKTAVILAGVLNLVGAFLS-VEVAVTVTTSVLKIQDSKTGQLIPSID
MAB_3950c|M.abscessus_ATCC_199 ALKPKTAVLLAGILNLVGAFLS-VEVAVTVTTSVIKVQDSKTGHLLPNIT
MLBr_02260|M.leprae_Br4923 ALAPKVAVFFSAILNLVGAFLS-TAVAATIAKDLIEAD------------
MAV_4599|M.avium_104 ALKPKTAVALSAVLNLVGAFMS-TAVAATIAKGLIDSN------------
Rv2281|M.tuberculosis_H37Rv TLTMKQALLVAAIFEVSGAVIAGGDVTETIRSGIVDLSG-------VSVD
Mb2302|M.bovis_AF2122/97 TLTMKQALLVAAIFEVSGAVIAGGDVTETIRSGIVDLSG-------VSVD
MMAR_3415|M.marinum_M TLSMKQALLVAAIFEVSGAVIAGGDVTETIRSGIVDLSG-------VSVA
MUL_2694|M.ulcerans_Agy99 TLSMKQALLVAAIFEVSGAVIAGGDVTETIRSGIVDLSG-------VSVA
:* * *: .:.:::: **.:: *: *: ..::. .
Mflv_0031|M.gilvum_PYR-GCK ASTGLTIIFAGLIGGILWNLLTWLFGIPSSSSHALFGGLIGAGLAALGLA
MSMEG_1064|M.smegmatis_MC2_155 ASTGLTIIFAGLIGGILWNLLTWLFGIPSSSSHALFGGLIGAGLAAIGLA
Mvan_0939|M.vanbaalenii_PYR-1 ASTGLTIIFAGLIGGILWNLLTWLFGIPSSSSHALFGGLIGAGLAAVGLA
MAB_3950c|M.abscessus_ATCC_199 PSMGLTIIFAGLIGGILWNLLTWLFGIPSSSSHALFGGLIGAALAAIGTS
MLBr_02260|M.leprae_Br4923 -LVTLELVFAGLVGGIVWNLLTWLLGIPSSSSHALIGGIVGARIAAVGGH
MAV_4599|M.avium_104 -IVTLELVFAGLVGGVVWNLLTWLLGIPSSSSHALIGGIVGATIAAVGAH
Rv2281|M.tuberculosis_H37Rv PRDFMNIMLSALSAAALWLLFANRMGYPVSTTHSIIGGIVGAAIALGMVS
Mb2302|M.bovis_AF2122/97 PRDFMNIMLSALSAAALWLLFANRMGYPVSTTHSIIGGIVGAAIALGMVS
MMAR_3415|M.marinum_M PNDFMNIMLAALLAAALWLLFANRMGYPVSTTHSIVGGIVGAAVTLGIVD
MUL_2694|M.ulcerans_Agy99 PNDFMNIMLAALLAAAMWLLFANRMGYPVSTTHSIVGGIVGAAVTLGIVD
: ::::.* .. :* *:: :* * *::*::.**::** ::
Mflv_0031|M.gilvum_PYR-GCK G---VNWSGVTQKVLIPALAAPMIACLVAGCGTWLVYRLTRRVAEKRRRE
MSMEG_1064|M.smegmatis_MC2_155 G---VNWAGVTQKVLIPAVAAPVIACLVASCGTWLIYRITRNVAQKRREQ
Mvan_0939|M.vanbaalenii_PYR-1 G---VNWSGVTQKVLIPAVAAPLIACLVAGCGTWLVYRITRNVMKNRREQ
MAB_3950c|M.abscessus_ATCC_199 G---VKWDGILQKVIIPAVAAPLIAGLVAAAGTWLVYRITRNVVKKRREE
MLBr_02260|M.leprae_Br4923 G---VIWSGVISKVIIPAIIAALLAIVVGAVATWLVYAITRSVPAMSTDT
MAV_4599|M.avium_104 G---VIWKGVISKAIIPAIVSAILAILVGAVATWLVYRITRGVPKKRTEA
Rv2281|M.tuberculosis_H37Rv GQGGAALRMVQWDQIGQIVVSWVLSPVLGGLVSYLLYGVIKRHILLYNEQ
Mb2302|M.bovis_AF2122/97 GQGGAALRMVQWDQIGQIVVSWVLSPVLGGLVSYLLYGVIKRHILLYNEQ
MMAR_3415|M.marinum_M GKGLSALQMVQWDEIGQIAISWVLSPLLGGLVSYALYGAIKRHILLYNEE
MUL_2694|M.ulcerans_Agy99 GKGLSALQMVQWDEIGQIAISWVLSPLLGGLVSYALYGAIKRHILLYNEE
* : . : : ::: ::.. :: :* :
Mflv_0031|M.gilvum_PYR-GCK GFRWGQIATASLVALSHGTNDAQKTMGVIALALITTGHLTGDVKEEG---
MSMEG_1064|M.smegmatis_MC2_155 GFRVGQIATASLVALSHGTNDAQKTMGVIALALITTGHLSGDVKENG---
Mvan_0939|M.vanbaalenii_PYR-1 GFRWGQIATASLVALSHGTNDAQKTMGVIALALITTGHLTGDVKEQG---
MAB_3950c|M.abscessus_ATCC_199 GFRWGQIATASLVALSHGTNDAQKTMGVIALALITTGHLTGNVKETG---
MLBr_02260|M.leprae_Br4923 RFRRGQIGSASLVSLAHGTNDAQKTMGVIFLALMSYGTVSKTASTP----
MAV_4599|M.avium_104 GFRRGQIGSASLVSLAHGTNDAQKTMGIIFLALISYGSVSKTAAMP----
Rv2281|M.tuberculosis_H37Rv AERRLTEIKKERIAHRERHKAAFDRLTEIQQIAYTGALARDAVAANRKDF
Mb2302|M.bovis_AF2122/97 AERRLTEIKKERIAHRERHKAAFDRLTEIQQIAYTGALARDAVAANRKDF
MMAR_3415|M.marinum_M AERKLLEIKKERIAHRERHKAAFERLSEIQQIAYTGAIARDAVAANRRDF
MUL_2694|M.ulcerans_Agy99 AERKLLEIKKERIAHRERHKAAFERLSEIQQIAYTGAFARDAVAANRRDF
* . . :: . : * . : * : . .
Mflv_0031|M.gilvum_PYR-GCK ----------------------------LPFWIIFSCAVAIGLGTYLGGW
MSMEG_1064|M.smegmatis_MC2_155 ----------------------------LPFWIIASCALAIGLGTYLGGW
Mvan_0939|M.vanbaalenii_PYR-1 ----------------------------LPIWIIASCALAIGLGTYLGGW
MAB_3950c|M.abscessus_ATCC_199 ----------------------------LPFWIIASCALAIGLGTYLGGW
MLBr_02260|M.leprae_Br4923 -----------------------------PLWVIVCCAIAIAAGTYLGGW
MAV_4599|M.avium_104 -----------------------------PLWVIVSCALAMATGTYLGGW
Rv2281|M.tuberculosis_H37Rv DPDELESDYYRELHEIDAKTSSVDAFRALQNWVPLVAAAGSMIIVAMLLF
Mb2302|M.bovis_AF2122/97 DPDELESDYYRELHEIDAKTSSVDAFRALQNWVPLVAAAGSMIIVAMLLF
MMAR_3415|M.marinum_M DPDELESDYYRELHEIDTKRSSVDAFRALQNWVPLVAAAGSMIISAMLLF
MUL_2694|M.ulcerans_Agy99 DPDELESDYYRELHEIDTKRSSVDAFRALQNWVPLVAAAGSMIISAMLLF
*: .* . : :
Mflv_0031|M.gilvum_PYR-GCK RVIRTLGKGLVEIQ------------------SPQGFAAEASSAAIILSS
MSMEG_1064|M.smegmatis_MC2_155 RVIRTLGKGLVEIE------------------SPQGLAAEASSAAIILSS
Mvan_0939|M.vanbaalenii_PYR-1 RVIRTLGKGLVEIE------------------SPQGLAAEASSAAIILSS
MAB_3950c|M.abscessus_ATCC_199 RVIRTLGKGLVEIE------------------SPQGLAAEASSAAIILSS
MLBr_02260|M.leprae_Br4923 RIIRTLGKGMVEIK------------------PPQGMAAESSSAAVILLS
MAV_4599|M.avium_104 RIIRTLGKGLVEIQ------------------SPQGMAAESSSAAVILLS
Rv2281|M.tuberculosis_H37Rv KGFKHMHLGLTTMNNYFIIAMVGAAVWMATFIFAKTLRGESLSRSTFLMF
Mb2302|M.bovis_AF2122/97 KGFKHMHLGLTTMNNYFIIAMVGAAVWMATFIFAKTLRGESLSRSTFLMF
MMAR_3415|M.marinum_M KGFKHMHLGLTTMNNFFIMGMVGAAVWMATFILAKTLRGESLSRSTYLMF
MUL_2694|M.ulcerans_Agy99 KGFKHMHLGLTTMNNFFIMGMVGAAVWMATFILAKTLRGESLSRSTYLMF
: :: : *:. :: .: : .*: * : *
Mflv_0031|M.gilvum_PYR-GCK ------SAAGMALSTTHVATGSILGSGVGKPGAEVRWAVAGRMAVAWLIT
MSMEG_1064|M.smegmatis_MC2_155 ------SAAGMALSTTHVATGSILGSGVGKPGAEVRWAVAGRMAVAWLVT
Mvan_0939|M.vanbaalenii_PYR-1 ------SAAGMALSTTHVATGSILGSGVGKPGAEVRWAVAGRMAVAWLIT
MAB_3950c|M.abscessus_ATCC_199 ------SAAGMALSTTHVATGSILGTGVGKPGAEVRWAVAGRMVLAWLVT
MLBr_02260|M.leprae_Br4923 ------AHFGYALSTTQVCTGSVLGSGLGKPGGEVRWGVAGRMATAWLVT
MAV_4599|M.avium_104 ------AHFGYALSTTQVCTGSVLGSGLGKPGGEVRWGVAGRMGVAWLVT
Rv2281|M.tuberculosis_H37Rv SWMQVFTASGFAFSHGSNDIANAIGPFAAILDVLRTGAIEGNAAVPAAAM
Mb2302|M.bovis_AF2122/97 SWMQVFTASGFAFSHGSNDIANAIGPFAAILDVLRTGAIEGNAAVPAAAM
MMAR_3415|M.marinum_M SWMQVFTASGFAFSHGSNDIANAIGPFAAVLDVLRSGSIEGKAAVPAAAM
MUL_2694|M.ulcerans_Agy99 SWMQVFTASGFAFSHGSNDIANAIGPFAAVLDVLRSGSIEGKAAVPAAAM
: * *:* .. :*. . . .: *. .
Mflv_0031|M.gilvum_PYR-GCK LPAAGLVGALTYWLSSGVTSATGSDLAGDGLIFVILVGLSAF-MWWRAQQ
MSMEG_1064|M.smegmatis_MC2_155 LPAAGIVGALAFWLSHGVERLTGSSLAGDGLIFMVLVGLSFY-MWWRAQQ
Mvan_0939|M.vanbaalenii_PYR-1 LPAAGIVGALSFWLSHGAESLTGSSLAGDGLIFLLLCGLSFY-LWWRAQQ
MAB_3950c|M.abscessus_ATCC_199 LPAAGIVGALSYWLSHLVGNLT-TPMVGDLIIFALLVVLSGY-MWWRAQQ
MLBr_02260|M.leprae_Br4923 LPLAGSVGAVTYWIVHLIGGYPGAVIG-----FSLLVAASVA-IYIRSRK
MAV_4599|M.avium_104 LPLAGLVGAVTYWIVHLIGGYPGAIIG-----FALLVAVSAT-IYLRSRK
Rv2281|M.tuberculosis_H37Rv VTFGVALCAGLWFIGRRVIATVGHNLTTMHPASGFAAELSAAGVVMGATV
Mb2302|M.bovis_AF2122/97 VTFGVALCAGLWFIGRRVIATVGHNLTTMHPASGFAAELSAAGVVMGATV
MMAR_3415|M.marinum_M ITFGVALCAGLWFIGRRVIATVGHNLTTMHPASGFAAELSAAGVVMGATV
MUL_2694|M.ulcerans_Agy99 ITFGVALCARLWFIGRRVIATVGHNLTTMHPASGFAAELSAAGVVMGATV
:. . : * ::: : . * : :
Mflv_0031|M.gilvum_PYR-GCK QKVDHKNVNADWDDTTNSVVPAELRVTTTPD-----------PKPVATV-
MSMEG_1064|M.smegmatis_MC2_155 QKVDHNNVNADWDESTNSVVPADLKVTIPDNS--------ERPTPAGV--
Mvan_0939|M.vanbaalenii_PYR-1 QKVDHSNVNADWDASTNSVVPAEVREATTNGTPPTDTKPPAGSKPAAAV-
MAB_3950c|M.abscessus_ATCC_199 EKVDSSNVNAEWDDSTNSVVPADVRESRAEAPVEAPNKQAPNKEAANKEA
MLBr_02260|M.leprae_Br4923 VKVDHKNVNENWEGSLTAGLDGSDEHKPHSDVGPKLSATLPRYRSSHHTV
MAV_4599|M.avium_104 VKVDHHNVNAEWKGDLTTGLEGADDHSPPPDAGPPFGGPGDRYQSDDPTL
Rv2281|M.tuberculosis_H37Rv LGLPVSSTHILIGAVLGVGIVNRSTNWGLMKPIVLAWVITLPSAAILASV
Mb2302|M.bovis_AF2122/97 LGLPVSSTHILIGAVLGVGIVNRSTNWGLMKPIVLAWVITLPSAAILASV
MMAR_3415|M.marinum_M LGLPVSSTHILIGAVLGVGIVNRATNWALMKPIALAWVITLPSAAILSAV
MUL_2694|M.ulcerans_Agy99 LGLPVSSTHILIGAVLGVGIVNRATNWALMKPIALAWVIALPSAAILSAV
: ..: : .
Mflv_0031|M.gilvum_PYR-GCK ------------
MSMEG_1064|M.smegmatis_MC2_155 ------------
Mvan_0939|M.vanbaalenii_PYR-1 ------------
MAB_3950c|M.abscessus_ATCC_199 PKKDSANDTASV
MLBr_02260|M.leprae_Br4923 GVRNAS------
MAV_4599|M.avium_104 KAS-AS------
Rv2281|M.tuberculosis_H37Rv GLVALRAIF---
Mb2302|M.bovis_AF2122/97 GLVALRAIF---
MMAR_3415|M.marinum_M GLVTLRAIF---
MUL_2694|M.ulcerans_Agy99 GLVTLRAIF---