For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MSAGQLRRHEIGKVTALTNPLSGHGAAVKAAHGAIARLKHRGVDVVEIVGGDAHDARHLLAAAVAKGTDA VMVTGGDGVVSNALQVLAGTDIPLGIIPAGTGNDHAREFGLPTKNPKAAADIVVDGWTETIDLGRIQDDN GIEKWFGTVAATGFDSLVNDRANRMRWPHGRMRYYIAMLAELSRLRPLPFRLVLDGTEEIVADLTLADFG NTRSYGGGLLICPNADHSDGLLDITMAQSDSRTKLLRLFPTIFKGAHVELDEVSTTRAKTVHVECPGINV YADGDFACPLPAEISAVPAALQVLRPRHG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2252 | - | - | 100% (309) | diacylglycerol kinase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2276 | - | 1e-179 | 100.00% (309) | diacylglycerol kinase |
| M. gilvum PYR-GCK | Mflv_2771 | - | 1e-113 | 66.55% (296) | diacylglycerol kinase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3885 | - | 4e-77 | 52.07% (290) | hypothetical protein MAB_3885 |
| M. marinum M | MMAR_3345 | - | 1e-140 | 79.15% (307) | hypothetical protein MMAR_3345 |
| M. avium 104 | MAV_2184 | - | 1e-142 | 79.21% (303) | diacylglycerol kinase |
| M. smegmatis MC2 155 | MSMEG_4335 | - | 1e-113 | 65.44% (298) | diacylglycerol kinase |
| M. thermoresistible (build 8) | TH_1506 | - | 1e-118 | 68.35% (297) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_1297 | - | 1e-137 | 77.85% (307) | diacylglycerol kinase |
| M. vanbaalenii PYR-1 | Mvan_3762 | - | 1e-115 | 66.33% (294) | diacylglycerol kinase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2771|M.gilvum_PYR-GCK ---------------MT---RVTVLTNPASGHGSASHAAERAITRLHRRG
Mvan_3762|M.vanbaalenii_PYR-1 ---------------MSPPARVTVLTNPTSGHGNAPHAAERAITRLHHRG
TH_1506|M.thermoresistible__bu ---------------VTVG-RITMLTNPASGHGSAPHAAERAAARFTARG
MSMEG_4335|M.smegmatis_MC2_155 ---------------MTG--RVTVLTNPMSGHGNAPHAAERAVVRLQQRG
Rv2252|M.tuberculosis_H37Rv --------MSAGQLRRHEIGKVTALTNPLSGHGAAVKAAHGAIARLKHRG
Mb2276|M.bovis_AF2122/97 --------MSAGQLRRHEIGKVTALTNPLSGHGAAVKAAHGAIARLKHRG
MMAR_3345|M.marinum_M MTPENPVNPLAGQLRQRSISKVTALTNPLSGHGAAVQAAQHAIARLHHRG
MUL_1297|M.ulcerans_Agy99 ---------MARQLRQRSISKVTALTNPLSGHGAAVQAAQHAIARLHHRG
MAV_2184|M.avium_104 ------MTSPAARLRRYEIGKVIALTNPASGHGAAVAAAQRAIARLHRRG
MAB_3885|M.abscessus_ATCC_1997 ------------------MTHLTVLTNPTAGHG-AAQAAEAAIAHLRARG
:: **** :*** * **. * .:: **
Mflv_2771|M.gilvum_PYR-GCK VDVVAIAGRDAVHARQLVEGALERDMDALVVVGGDGIISLALQVLAQTDI
Mvan_3762|M.vanbaalenii_PYR-1 VDVVAIAGRDSSHARQLVEGALERGMDALVVVGGDGIISLALQVLAQTDI
TH_1506|M.thermoresistible__bu VDVVAIAGRDADHARRLVEGALDHDMDALVVVGGDGVVSLALQVLAGTDV
MSMEG_4335|M.smegmatis_MC2_155 VDVTAIVGRDARHARELVREHLDRGTDALVVVGGDGVIGLALQELAGTDV
Rv2252|M.tuberculosis_H37Rv VDVVEIVGGDAHDARHLLAAAVAKGTDAVMVTGGDGVVSNALQVLAGTDI
Mb2276|M.bovis_AF2122/97 VDVVEIVGGDAHDARHLLAAAVAKGTDAVMVTGGDGVVSNALQVLAGTDI
MMAR_3345|M.marinum_M VEVIEIVGENAEDARYLLAAAVEKGTDAVVVTGGDGVISNALQVLAETDV
MUL_1297|M.ulcerans_Agy99 VEVIEIVGENAEDARYLLAAAVEKGTDAVVVTGGDGVISNALQVLAETDV
MAV_2184|M.avium_104 VEVVEIIGDDAQDARHLVGAALDKGADAVMVTGGDGVFSNALQVLAGTDI
MAB_3885|M.abscessus_ATCC_1997 LTVTHHAATSAAESHALAQEAARTGARGIVAAGGDGLVSIALQAVAATPV
: * . .: .:: * . .::..****:.. *** :* * :
Mflv_2771|M.gilvum_PYR-GCK PLGVIPAGTGNDHAREFGIPTGDPEAAADVVVDGVSDHVDLGRISGADG-
Mvan_3762|M.vanbaalenii_PYR-1 PLGLVPAGTGNDHAREFGIPTRDPEAAADVIVDGVADTVDLGRIKGADG-
TH_1506|M.thermoresistible__bu PLGIIPAGTGNDHAREFGIPTKDPEAAADVVVDGVTEVVDLGRIRGADG-
MSMEG_4335|M.smegmatis_MC2_155 PLGIVPAGTGNDHAREYRIPTGDPEAAADVIADGHTRTVDLGRIDADDG-
Rv2252|M.tuberculosis_H37Rv PLGIIPAGTGNDHAREFGLPTKNPKAAADIVVDGWTETIDLGRIQDDNG-
Mb2276|M.bovis_AF2122/97 PLGIIPAGTGNDHAREFGLPTKNPKAAADIVVDGWTETIDLGRIQDDNG-
MMAR_3345|M.marinum_M PLGIIPAGTGNDHAREFEIPTKDAEAAADIVVDGWTETIDLGRIQAGSGK
MUL_1297|M.ulcerans_Agy99 PLGIIPAGTGNDHAREFEIPTKDAEAAADIVVDGWTETIDLGPIQAGSGK
MAV_2184|M.avium_104 PAGIVPAGTGNDHAREFGIPTKDPEAAADIIVDGWAETVDLGRIRADNG-
MAB_3885|M.abscessus_ATCC_1997 ALGVIPIGTGNDCARMLDIPLSDPVAAAEVIAAGRIRVIDAGRIQYHGD-
. *::* ***** ** :* :. ***:::. * :* * * ..
Mflv_2771|M.gilvum_PYR-GCK --TVRWFGTVMAAGFDSLVTDRTNRMRWPHGRMRYNLAMVAEISKLRLLP
Mvan_3762|M.vanbaalenii_PYR-1 --TDRWFGTVMAAGFDSLVTDRTNRMRWPHGRMRYNLAMVAELSKLRLLP
TH_1506|M.thermoresistible__bu --TDKWFGTVLAAGFDSLVTDRTNRMRWPHGRMRYNLAVLAELSKLRLLP
MSMEG_4335|M.smegmatis_MC2_155 --TRRWFGTVVATGFDSLVSDRANRMSWPHGRMRYNLAMVAELSKLRLLP
Rv2252|M.tuberculosis_H37Rv --IEKWFGTVAATGFDSLVNDRANRMRWPHGRMRYYIAMLAELSRLRPLP
Mb2276|M.bovis_AF2122/97 --IEKWFGTVAATGFDSLVNDRANRMRWPHGRMRYYIAMLAELSRLRPLP
MMAR_3345|M.marinum_M DKCDKWFGTLAATGFDSLVTDRANRMTWPHGRLRYYIAMLVELSQLRPLP
MUL_1297|M.ulcerans_Agy99 DKCDKWFGTLAATGFDSLVTDRANRMTWPHGRLRYYIAMLVELSQLRPLP
MAV_2184|M.avium_104 --FDKWFGTVAATGFDSLVTDRANRMRWPHGRLRYYVAMLAELSQLRLLP
MAB_3885|M.abscessus_ATCC_1997 ---TTWFATVVASGFDSLVNDRANRMRWPRGRRRYDIAMALEAAKLRPLP
**.*: *:******.**:*** **:** ** :*: * ::** **
Mflv_2771|M.gilvum_PYR-GCK FRLSFDGD-EISTQLTLAAFGNTRSYGGGMKICPGADPRDGLLDVTMVAS
Mvan_3762|M.vanbaalenii_PYR-1 FRLSFDGDAEFDTELTLAAFGNTKSYGGGMKICPDADPRDGLLDATMVAS
TH_1506|M.thermoresistible__bu FRLTLDGR-EVQTMLTLAAVGNTRSYGGGMLICPNADPRDGLLDVTMIAT
MSMEG_4335|M.smegmatis_MC2_155 FRLSFDGGDAEDHALTMTAIGNTRSYGGGMLICPGADPTDGLLDITMIAS
Rv2252|M.tuberculosis_H37Rv FRLVLDGTEEIVADLTLADFGNTRSYGGGLLICPNADHSDGLLDITMAQS
Mb2276|M.bovis_AF2122/97 FRLVLDGTEEIVADLTLADFGNTRSYGGGLLICPNADHSDGLLDITMAQS
MMAR_3345|M.marinum_M FRLVLDGTEEIETDLTLATFGNTRSYGGGMLMCPNADRTDGLLDITMVRS
MUL_1297|M.ulcerans_Agy99 FRLVLDGTEEIETDLTLATFGNTRSYGGGMLMCPNADRTDDLLDITMVRS
MAV_2184|M.avium_104 FRLVLDGAREIDADITLAAFGNTRSYGGGMRICPAADHADGLLDITMVHE
MAB_3885|M.abscessus_ATCC_1997 FRIELDDQ-VIDTDVTLVAVGNGTSYGGGMRICPGAILDDGLLDITVVAA
**: :*. :*:. .** *****: :** * *.*** *:
Mflv_2771|M.gilvum_PYR-GCK ASRTRLIRLFPTVFKGTHVNLDEVSTRRARTITVDSPGINSYADGEYVCP
Mvan_3762|M.vanbaalenii_PYR-1 ASRTRLIRLFPTVFKGTHVNLDEVRTARARTITVDSPGINAYADGEYVCP
TH_1506|M.thermoresistible__bu ESRTRLIRLFPTVFKGTHVELDEVTTERVRTIGIDCPGINAYADGEYACP
MSMEG_4335|M.smegmatis_MC2_155 ASRSRLIRLFPTVFKGTHVNLDTVTTRRARSVRVECPGINAYADGDFAAP
Rv2252|M.tuberculosis_H37Rv DSRTKLLRLFPTIFKGAHVELDEVSTTRAKTVHVECPGINVYADGDFACP
Mb2276|M.bovis_AF2122/97 DSRTKLLRLFPTIFKGAHVELDEVSTTRAKTVHVECPGINVYADGDFACP
MMAR_3345|M.marinum_M GSRSRFLRLFPTVVKGTHVELDEVTTARAKSIDVECPGINVYADGDYACP
MUL_1297|M.ulcerans_Agy99 GPRSSFLRLFPTVVKGTHVELDEVTTARAKSIDVECPGINVYADGDYACP
MAV_2184|M.avium_104 ASRAKLVRLFPTVMKGTHVELEQVSTARAKSIHVECPGINVYADGDFACP
MAB_3885|M.abscessus_ATCC_1997 GGRLRLLRLSPTVYKGTHVDLPEVSTFRSRRVRLSAADITAYADGDPVAP
* ::** **: **:**:* * * * : : :....*. ****: ..*
Mflv_2771|M.gilvum_PYR-GCK LPVEVSAVPKALKILRPA--
Mvan_3762|M.vanbaalenii_PYR-1 LPVEVSAVPGALKILRPS--
TH_1506|M.thermoresistible__bu LPVEVSAVPGALRIRTPRR-
MSMEG_4335|M.smegmatis_MC2_155 LPATITAVPGALKILTSAPG
Rv2252|M.tuberculosis_H37Rv LPAEISAVPAALQVLRPRHG
Mb2276|M.bovis_AF2122/97 LPAEISAVPAALQVLRPRHG
MMAR_3345|M.marinum_M LPANISAVAGALQILRPNDR
MUL_1297|M.ulcerans_Agy99 LPANISAVAGALQILRPNDR
MAV_2184|M.avium_104 LPAEISAVPGALRILRAGP-
MAB_3885|M.abscessus_ATCC_1997 LPVDIDVVPGALSVFA----
**. : .*. ** :