For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. vanbaalenii PYR-1 Mvan_3762 (-)

annotation: diacylglycerol kinase
coordinates: 4003977 - 4004879
length: 300

VSPPARVTVLTNPTSGHGNAPHAAERAITRLHHRGVDVVAIAGRDSSHARQLVEGALERGMDALVVVGGD
GIISLALQVLAQTDIPLGLVPAGTGNDHAREFGIPTRDPEAAADVIVDGVADTVDLGRIKGADGTDRWFG
TVMAAGFDSLVTDRTNRMRWPHGRMRYNLAMVAELSKLRLLPFRLSFDGDAEFDTELTLAAFGNTKSYGG
GMKICPDADPRDGLLDATMVASASRTRLIRLFPTVFKGTHVNLDEVRTARARTITVDSPGINAYADGEYV
CPLPVEVSAVPGALKILRPS
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. vanbaalenii PYR-1Mvan_3762--100% (300)diacylglycerol kinase
M. vanbaalenii PYR-1Mvan_0430-2e-0925.16% (310) phosphoesterase, PA-phosphatase related
M. vanbaalenii PYR-1Mvan_1783-3e-0623.94% (330) diacylglycerol kinase, catalytic region

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2276-1e-11666.33% (294) diacylglycerol kinase
M. gilvum PYR-GCKMflv_2771-1e-15290.51% (295) diacylglycerol kinase
M. tuberculosis H37RvRv2252-1e-11666.33% (294) diacylglycerol kinase
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_3885-2e-8153.45% (290) hypothetical protein MAB_3885
M. marinum MMMAR_3345-1e-11766.56% (299) hypothetical protein MMAR_3345
M. avium 104MAV_2184-1e-12070.65% (293) diacylglycerol kinase
M. smegmatis MC2 155MSMEG_4335-1e-12776.37% (292) diacylglycerol kinase
M. thermoresistible (build 8)TH_1506-1e-13980.61% (294) CONSERVED HYPOTHETICAL PROTEIN
M. ulcerans Agy99MUL_1297-1e-11465.22% (299) diacylglycerol kinase

CLUSTAL 2.0.9 multiple sequence alignment


Mvan_3762|M.vanbaalenii_PYR-1       ---------------MSPPARVTVLTNPTSGHGNAPHAAERAITRLHHRG
Mflv_2771|M.gilvum_PYR-GCK          ---------------MT---RVTVLTNPASGHGSASHAAERAITRLHRRG
TH_1506|M.thermoresistible__bu      ---------------VTVG-RITMLTNPASGHGSAPHAAERAAARFTARG
MSMEG_4335|M.smegmatis_MC2_155      ---------------MTG--RVTVLTNPMSGHGNAPHAAERAVVRLQQRG
Mb2276|M.bovis_AF2122/97            --------MSAGQLRRHEIGKVTALTNPLSGHGAAVKAAHGAIARLKHRG
Rv2252|M.tuberculosis_H37Rv         --------MSAGQLRRHEIGKVTALTNPLSGHGAAVKAAHGAIARLKHRG
MMAR_3345|M.marinum_M               MTPENPVNPLAGQLRQRSISKVTALTNPLSGHGAAVQAAQHAIARLHHRG
MUL_1297|M.ulcerans_Agy99           ---------MARQLRQRSISKVTALTNPLSGHGAAVQAAQHAIARLHHRG
MAV_2184|M.avium_104                ------MTSPAARLRRYEIGKVIALTNPASGHGAAVAAAQRAIARLHRRG
MAB_3885|M.abscessus_ATCC_1997      ------------------MTHLTVLTNPTAGHG-AAQAAEAAIAHLRARG
                                                        ::  **** :*** *  **. * .::  **

Mvan_3762|M.vanbaalenii_PYR-1       VDVVAIAGRDSSHARQLVEGALERGMDALVVVGGDGIISLALQVLAQTDI
Mflv_2771|M.gilvum_PYR-GCK          VDVVAIAGRDAVHARQLVEGALERDMDALVVVGGDGIISLALQVLAQTDI
TH_1506|M.thermoresistible__bu      VDVVAIAGRDADHARRLVEGALDHDMDALVVVGGDGVVSLALQVLAGTDV
MSMEG_4335|M.smegmatis_MC2_155      VDVTAIVGRDARHARELVREHLDRGTDALVVVGGDGVIGLALQELAGTDV
Mb2276|M.bovis_AF2122/97            VDVVEIVGGDAHDARHLLAAAVAKGTDAVMVTGGDGVVSNALQVLAGTDI
Rv2252|M.tuberculosis_H37Rv         VDVVEIVGGDAHDARHLLAAAVAKGTDAVMVTGGDGVVSNALQVLAGTDI
MMAR_3345|M.marinum_M               VEVIEIVGENAEDARYLLAAAVEKGTDAVVVTGGDGVISNALQVLAETDV
MUL_1297|M.ulcerans_Agy99           VEVIEIVGENAEDARYLLAAAVEKGTDAVVVTGGDGVISNALQVLAETDV
MAV_2184|M.avium_104                VEVVEIIGDDAQDARHLVGAALDKGADAVMVTGGDGVFSNALQVLAGTDI
MAB_3885|M.abscessus_ATCC_1997      LTVTHHAATSAAESHALAQEAARTGARGIVAAGGDGLVSIALQAVAATPV
                                    : *    . .: .:: *       .  .::..****:.. *** :* * :

Mvan_3762|M.vanbaalenii_PYR-1       PLGLVPAGTGNDHAREFGIPTRDPEAAADVIVDGVADTVDLGRIKGADG-
Mflv_2771|M.gilvum_PYR-GCK          PLGVIPAGTGNDHAREFGIPTGDPEAAADVVVDGVSDHVDLGRISGADG-
TH_1506|M.thermoresistible__bu      PLGIIPAGTGNDHAREFGIPTKDPEAAADVVVDGVTEVVDLGRIRGADG-
MSMEG_4335|M.smegmatis_MC2_155      PLGIVPAGTGNDHAREYRIPTGDPEAAADVIADGHTRTVDLGRIDADDG-
Mb2276|M.bovis_AF2122/97            PLGIIPAGTGNDHAREFGLPTKNPKAAADIVVDGWTETIDLGRIQDDNG-
Rv2252|M.tuberculosis_H37Rv         PLGIIPAGTGNDHAREFGLPTKNPKAAADIVVDGWTETIDLGRIQDDNG-
MMAR_3345|M.marinum_M               PLGIIPAGTGNDHAREFEIPTKDAEAAADIVVDGWTETIDLGRIQAGSGK
MUL_1297|M.ulcerans_Agy99           PLGIIPAGTGNDHAREFEIPTKDAEAAADIVVDGWTETIDLGPIQAGSGK
MAV_2184|M.avium_104                PAGIVPAGTGNDHAREFGIPTKDPEAAADIIVDGWAETVDLGRIRADNG-
MAB_3885|M.abscessus_ATCC_1997      ALGVIPIGTGNDCARMLDIPLSDPVAAAEVIAAGRIRVIDAGRIQYHGD-
                                    . *::* ***** **   :*  :. ***:::. *    :* * *   .. 

Mvan_3762|M.vanbaalenii_PYR-1       --TDRWFGTVMAAGFDSLVTDRTNRMRWPHGRMRYNLAMVAELSKLRLLP
Mflv_2771|M.gilvum_PYR-GCK          --TVRWFGTVMAAGFDSLVTDRTNRMRWPHGRMRYNLAMVAEISKLRLLP
TH_1506|M.thermoresistible__bu      --TDKWFGTVLAAGFDSLVTDRTNRMRWPHGRMRYNLAVLAELSKLRLLP
MSMEG_4335|M.smegmatis_MC2_155      --TRRWFGTVVATGFDSLVSDRANRMSWPHGRMRYNLAMVAELSKLRLLP
Mb2276|M.bovis_AF2122/97            --IEKWFGTVAATGFDSLVNDRANRMRWPHGRMRYYIAMLAELSRLRPLP
Rv2252|M.tuberculosis_H37Rv         --IEKWFGTVAATGFDSLVNDRANRMRWPHGRMRYYIAMLAELSRLRPLP
MMAR_3345|M.marinum_M               DKCDKWFGTLAATGFDSLVTDRANRMTWPHGRLRYYIAMLVELSQLRPLP
MUL_1297|M.ulcerans_Agy99           DKCDKWFGTLAATGFDSLVTDRANRMTWPHGRLRYYIAMLVELSQLRPLP
MAV_2184|M.avium_104                --FDKWFGTVAATGFDSLVTDRANRMRWPHGRLRYYVAMLAELSQLRLLP
MAB_3885|M.abscessus_ATCC_1997      ---TTWFATVVASGFDSLVNDRANRMRWPRGRRRYDIAMALEAAKLRPLP
                                         **.*: *:******.**:*** **:** ** :*:  * ::** **

Mvan_3762|M.vanbaalenii_PYR-1       FRLSFDGDAEFDTELTLAAFGNTKSYGGGMKICPDADPRDGLLDATMVAS
Mflv_2771|M.gilvum_PYR-GCK          FRLSFDGD-EISTQLTLAAFGNTRSYGGGMKICPGADPRDGLLDVTMVAS
TH_1506|M.thermoresistible__bu      FRLTLDGR-EVQTMLTLAAVGNTRSYGGGMLICPNADPRDGLLDVTMIAT
MSMEG_4335|M.smegmatis_MC2_155      FRLSFDGGDAEDHALTMTAIGNTRSYGGGMLICPGADPTDGLLDITMIAS
Mb2276|M.bovis_AF2122/97            FRLVLDGTEEIVADLTLADFGNTRSYGGGLLICPNADHSDGLLDITMAQS
Rv2252|M.tuberculosis_H37Rv         FRLVLDGTEEIVADLTLADFGNTRSYGGGLLICPNADHSDGLLDITMAQS
MMAR_3345|M.marinum_M               FRLVLDGTEEIETDLTLATFGNTRSYGGGMLMCPNADRTDGLLDITMVRS
MUL_1297|M.ulcerans_Agy99           FRLVLDGTEEIETDLTLATFGNTRSYGGGMLMCPNADRTDDLLDITMVRS
MAV_2184|M.avium_104                FRLVLDGAREIDADITLAAFGNTRSYGGGMRICPAADHADGLLDITMVHE
MAB_3885|M.abscessus_ATCC_1997      FRIELDDQ-VIDTDVTLVAVGNGTSYGGGMRICPGAILDDGLLDITVVAA
                                    **: :*.       :*:. .**  *****: :** *   *.*** *:   

Mvan_3762|M.vanbaalenii_PYR-1       ASRTRLIRLFPTVFKGTHVNLDEVRTARARTITVDSPGINAYADGEYVCP
Mflv_2771|M.gilvum_PYR-GCK          ASRTRLIRLFPTVFKGTHVNLDEVSTRRARTITVDSPGINSYADGEYVCP
TH_1506|M.thermoresistible__bu      ESRTRLIRLFPTVFKGTHVELDEVTTERVRTIGIDCPGINAYADGEYACP
MSMEG_4335|M.smegmatis_MC2_155      ASRSRLIRLFPTVFKGTHVNLDTVTTRRARSVRVECPGINAYADGDFAAP
Mb2276|M.bovis_AF2122/97            DSRTKLLRLFPTIFKGAHVELDEVSTTRAKTVHVECPGINVYADGDFACP
Rv2252|M.tuberculosis_H37Rv         DSRTKLLRLFPTIFKGAHVELDEVSTTRAKTVHVECPGINVYADGDFACP
MMAR_3345|M.marinum_M               GSRSRFLRLFPTVVKGTHVELDEVTTARAKSIDVECPGINVYADGDYACP
MUL_1297|M.ulcerans_Agy99           GPRSSFLRLFPTVVKGTHVELDEVTTARAKSIDVECPGINVYADGDYACP
MAV_2184|M.avium_104                ASRAKLVRLFPTVMKGTHVELEQVSTARAKSIHVECPGINVYADGDFACP
MAB_3885|M.abscessus_ATCC_1997      GGRLRLLRLSPTVYKGTHVDLPEVSTFRSRRVRLSAADITAYADGDPVAP
                                      *  ::** **: **:**:*  * * * : : :....*. ****: ..*

Mvan_3762|M.vanbaalenii_PYR-1       LPVEVSAVPGALKILRPS--
Mflv_2771|M.gilvum_PYR-GCK          LPVEVSAVPKALKILRPA--
TH_1506|M.thermoresistible__bu      LPVEVSAVPGALRIRTPRR-
MSMEG_4335|M.smegmatis_MC2_155      LPATITAVPGALKILTSAPG
Mb2276|M.bovis_AF2122/97            LPAEISAVPAALQVLRPRHG
Rv2252|M.tuberculosis_H37Rv         LPAEISAVPAALQVLRPRHG
MMAR_3345|M.marinum_M               LPANISAVAGALQILRPNDR
MUL_1297|M.ulcerans_Agy99           LPANISAVAGALQILRPNDR
MAV_2184|M.avium_104                LPAEISAVPGALRILRAGP-
MAB_3885|M.abscessus_ATCC_1997      LPVDIDVVPGALSVFA----
                                    **. : .*. ** :