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VSPPARVTVLTNPTSGHGNAPHAAERAITRLHHRGVDVVAIAGRDSSHARQLVEGALERGMDALVVVGGD GIISLALQVLAQTDIPLGLVPAGTGNDHAREFGIPTRDPEAAADVIVDGVADTVDLGRIKGADGTDRWFG TVMAAGFDSLVTDRTNRMRWPHGRMRYNLAMVAELSKLRLLPFRLSFDGDAEFDTELTLAAFGNTKSYGG GMKICPDADPRDGLLDATMVASASRTRLIRLFPTVFKGTHVNLDEVRTARARTITVDSPGINAYADGEYV CPLPVEVSAVPGALKILRPS
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. vanbaalenii PYR-1 | Mvan_3762 | - | - | 100% (300) | diacylglycerol kinase |
M. vanbaalenii PYR-1 | Mvan_0430 | - | 2e-09 | 25.16% (310) | phosphoesterase, PA-phosphatase related |
M. vanbaalenii PYR-1 | Mvan_1783 | - | 3e-06 | 23.94% (330) | diacylglycerol kinase, catalytic region |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2276 | - | 1e-116 | 66.33% (294) | diacylglycerol kinase |
M. gilvum PYR-GCK | Mflv_2771 | - | 1e-152 | 90.51% (295) | diacylglycerol kinase |
M. tuberculosis H37Rv | Rv2252 | - | 1e-116 | 66.33% (294) | diacylglycerol kinase |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_3885 | - | 2e-81 | 53.45% (290) | hypothetical protein MAB_3885 |
M. marinum M | MMAR_3345 | - | 1e-117 | 66.56% (299) | hypothetical protein MMAR_3345 |
M. avium 104 | MAV_2184 | - | 1e-120 | 70.65% (293) | diacylglycerol kinase |
M. smegmatis MC2 155 | MSMEG_4335 | - | 1e-127 | 76.37% (292) | diacylglycerol kinase |
M. thermoresistible (build 8) | TH_1506 | - | 1e-139 | 80.61% (294) | CONSERVED HYPOTHETICAL PROTEIN |
M. ulcerans Agy99 | MUL_1297 | - | 1e-114 | 65.22% (299) | diacylglycerol kinase |
CLUSTAL 2.0.9 multiple sequence alignment Mvan_3762|M.vanbaalenii_PYR-1 ---------------MSPPARVTVLTNPTSGHGNAPHAAERAITRLHHRG Mflv_2771|M.gilvum_PYR-GCK ---------------MT---RVTVLTNPASGHGSASHAAERAITRLHRRG TH_1506|M.thermoresistible__bu ---------------VTVG-RITMLTNPASGHGSAPHAAERAAARFTARG MSMEG_4335|M.smegmatis_MC2_155 ---------------MTG--RVTVLTNPMSGHGNAPHAAERAVVRLQQRG Mb2276|M.bovis_AF2122/97 --------MSAGQLRRHEIGKVTALTNPLSGHGAAVKAAHGAIARLKHRG Rv2252|M.tuberculosis_H37Rv --------MSAGQLRRHEIGKVTALTNPLSGHGAAVKAAHGAIARLKHRG MMAR_3345|M.marinum_M MTPENPVNPLAGQLRQRSISKVTALTNPLSGHGAAVQAAQHAIARLHHRG MUL_1297|M.ulcerans_Agy99 ---------MARQLRQRSISKVTALTNPLSGHGAAVQAAQHAIARLHHRG MAV_2184|M.avium_104 ------MTSPAARLRRYEIGKVIALTNPASGHGAAVAAAQRAIARLHRRG MAB_3885|M.abscessus_ATCC_1997 ------------------MTHLTVLTNPTAGHG-AAQAAEAAIAHLRARG :: **** :*** * **. * .:: ** Mvan_3762|M.vanbaalenii_PYR-1 VDVVAIAGRDSSHARQLVEGALERGMDALVVVGGDGIISLALQVLAQTDI Mflv_2771|M.gilvum_PYR-GCK VDVVAIAGRDAVHARQLVEGALERDMDALVVVGGDGIISLALQVLAQTDI TH_1506|M.thermoresistible__bu VDVVAIAGRDADHARRLVEGALDHDMDALVVVGGDGVVSLALQVLAGTDV MSMEG_4335|M.smegmatis_MC2_155 VDVTAIVGRDARHARELVREHLDRGTDALVVVGGDGVIGLALQELAGTDV Mb2276|M.bovis_AF2122/97 VDVVEIVGGDAHDARHLLAAAVAKGTDAVMVTGGDGVVSNALQVLAGTDI Rv2252|M.tuberculosis_H37Rv VDVVEIVGGDAHDARHLLAAAVAKGTDAVMVTGGDGVVSNALQVLAGTDI MMAR_3345|M.marinum_M VEVIEIVGENAEDARYLLAAAVEKGTDAVVVTGGDGVISNALQVLAETDV MUL_1297|M.ulcerans_Agy99 VEVIEIVGENAEDARYLLAAAVEKGTDAVVVTGGDGVISNALQVLAETDV MAV_2184|M.avium_104 VEVVEIIGDDAQDARHLVGAALDKGADAVMVTGGDGVFSNALQVLAGTDI MAB_3885|M.abscessus_ATCC_1997 LTVTHHAATSAAESHALAQEAARTGARGIVAAGGDGLVSIALQAVAATPV : * . .: .:: * . .::..****:.. *** :* * : Mvan_3762|M.vanbaalenii_PYR-1 PLGLVPAGTGNDHAREFGIPTRDPEAAADVIVDGVADTVDLGRIKGADG- Mflv_2771|M.gilvum_PYR-GCK PLGVIPAGTGNDHAREFGIPTGDPEAAADVVVDGVSDHVDLGRISGADG- TH_1506|M.thermoresistible__bu PLGIIPAGTGNDHAREFGIPTKDPEAAADVVVDGVTEVVDLGRIRGADG- MSMEG_4335|M.smegmatis_MC2_155 PLGIVPAGTGNDHAREYRIPTGDPEAAADVIADGHTRTVDLGRIDADDG- Mb2276|M.bovis_AF2122/97 PLGIIPAGTGNDHAREFGLPTKNPKAAADIVVDGWTETIDLGRIQDDNG- Rv2252|M.tuberculosis_H37Rv PLGIIPAGTGNDHAREFGLPTKNPKAAADIVVDGWTETIDLGRIQDDNG- MMAR_3345|M.marinum_M PLGIIPAGTGNDHAREFEIPTKDAEAAADIVVDGWTETIDLGRIQAGSGK MUL_1297|M.ulcerans_Agy99 PLGIIPAGTGNDHAREFEIPTKDAEAAADIVVDGWTETIDLGPIQAGSGK MAV_2184|M.avium_104 PAGIVPAGTGNDHAREFGIPTKDPEAAADIIVDGWAETVDLGRIRADNG- MAB_3885|M.abscessus_ATCC_1997 ALGVIPIGTGNDCARMLDIPLSDPVAAAEVIAAGRIRVIDAGRIQYHGD- . *::* ***** ** :* :. ***:::. * :* * * .. Mvan_3762|M.vanbaalenii_PYR-1 --TDRWFGTVMAAGFDSLVTDRTNRMRWPHGRMRYNLAMVAELSKLRLLP Mflv_2771|M.gilvum_PYR-GCK --TVRWFGTVMAAGFDSLVTDRTNRMRWPHGRMRYNLAMVAEISKLRLLP TH_1506|M.thermoresistible__bu --TDKWFGTVLAAGFDSLVTDRTNRMRWPHGRMRYNLAVLAELSKLRLLP MSMEG_4335|M.smegmatis_MC2_155 --TRRWFGTVVATGFDSLVSDRANRMSWPHGRMRYNLAMVAELSKLRLLP Mb2276|M.bovis_AF2122/97 --IEKWFGTVAATGFDSLVNDRANRMRWPHGRMRYYIAMLAELSRLRPLP Rv2252|M.tuberculosis_H37Rv --IEKWFGTVAATGFDSLVNDRANRMRWPHGRMRYYIAMLAELSRLRPLP MMAR_3345|M.marinum_M DKCDKWFGTLAATGFDSLVTDRANRMTWPHGRLRYYIAMLVELSQLRPLP MUL_1297|M.ulcerans_Agy99 DKCDKWFGTLAATGFDSLVTDRANRMTWPHGRLRYYIAMLVELSQLRPLP MAV_2184|M.avium_104 --FDKWFGTVAATGFDSLVTDRANRMRWPHGRLRYYVAMLAELSQLRLLP MAB_3885|M.abscessus_ATCC_1997 ---TTWFATVVASGFDSLVNDRANRMRWPRGRRRYDIAMALEAAKLRPLP **.*: *:******.**:*** **:** ** :*: * ::** ** Mvan_3762|M.vanbaalenii_PYR-1 FRLSFDGDAEFDTELTLAAFGNTKSYGGGMKICPDADPRDGLLDATMVAS Mflv_2771|M.gilvum_PYR-GCK FRLSFDGD-EISTQLTLAAFGNTRSYGGGMKICPGADPRDGLLDVTMVAS TH_1506|M.thermoresistible__bu FRLTLDGR-EVQTMLTLAAVGNTRSYGGGMLICPNADPRDGLLDVTMIAT MSMEG_4335|M.smegmatis_MC2_155 FRLSFDGGDAEDHALTMTAIGNTRSYGGGMLICPGADPTDGLLDITMIAS Mb2276|M.bovis_AF2122/97 FRLVLDGTEEIVADLTLADFGNTRSYGGGLLICPNADHSDGLLDITMAQS Rv2252|M.tuberculosis_H37Rv FRLVLDGTEEIVADLTLADFGNTRSYGGGLLICPNADHSDGLLDITMAQS MMAR_3345|M.marinum_M FRLVLDGTEEIETDLTLATFGNTRSYGGGMLMCPNADRTDGLLDITMVRS MUL_1297|M.ulcerans_Agy99 FRLVLDGTEEIETDLTLATFGNTRSYGGGMLMCPNADRTDDLLDITMVRS MAV_2184|M.avium_104 FRLVLDGAREIDADITLAAFGNTRSYGGGMRICPAADHADGLLDITMVHE MAB_3885|M.abscessus_ATCC_1997 FRIELDDQ-VIDTDVTLVAVGNGTSYGGGMRICPGAILDDGLLDITVVAA **: :*. :*:. .** *****: :** * *.*** *: Mvan_3762|M.vanbaalenii_PYR-1 ASRTRLIRLFPTVFKGTHVNLDEVRTARARTITVDSPGINAYADGEYVCP Mflv_2771|M.gilvum_PYR-GCK ASRTRLIRLFPTVFKGTHVNLDEVSTRRARTITVDSPGINSYADGEYVCP TH_1506|M.thermoresistible__bu ESRTRLIRLFPTVFKGTHVELDEVTTERVRTIGIDCPGINAYADGEYACP MSMEG_4335|M.smegmatis_MC2_155 ASRSRLIRLFPTVFKGTHVNLDTVTTRRARSVRVECPGINAYADGDFAAP Mb2276|M.bovis_AF2122/97 DSRTKLLRLFPTIFKGAHVELDEVSTTRAKTVHVECPGINVYADGDFACP Rv2252|M.tuberculosis_H37Rv DSRTKLLRLFPTIFKGAHVELDEVSTTRAKTVHVECPGINVYADGDFACP MMAR_3345|M.marinum_M GSRSRFLRLFPTVVKGTHVELDEVTTARAKSIDVECPGINVYADGDYACP MUL_1297|M.ulcerans_Agy99 GPRSSFLRLFPTVVKGTHVELDEVTTARAKSIDVECPGINVYADGDYACP MAV_2184|M.avium_104 ASRAKLVRLFPTVMKGTHVELEQVSTARAKSIHVECPGINVYADGDFACP MAB_3885|M.abscessus_ATCC_1997 GGRLRLLRLSPTVYKGTHVDLPEVSTFRSRRVRLSAADITAYADGDPVAP * ::** **: **:**:* * * * : : :....*. ****: ..* Mvan_3762|M.vanbaalenii_PYR-1 LPVEVSAVPGALKILRPS-- Mflv_2771|M.gilvum_PYR-GCK LPVEVSAVPKALKILRPA-- TH_1506|M.thermoresistible__bu LPVEVSAVPGALRIRTPRR- MSMEG_4335|M.smegmatis_MC2_155 LPATITAVPGALKILTSAPG Mb2276|M.bovis_AF2122/97 LPAEISAVPAALQVLRPRHG Rv2252|M.tuberculosis_H37Rv LPAEISAVPAALQVLRPRHG MMAR_3345|M.marinum_M LPANISAVAGALQILRPNDR MUL_1297|M.ulcerans_Agy99 LPANISAVAGALQILRPNDR MAV_2184|M.avium_104 LPAEISAVPGALRILRAGP- MAB_3885|M.abscessus_ATCC_1997 LPVDIDVVPGALSVFA---- **. : .*. ** :