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VSPPARVTVLTNPTSGHGNAPHAAERAITRLHHRGVDVVAIAGRDSSHARQLVEGALERGMDALVVVGGD GIISLALQVLAQTDIPLGLVPAGTGNDHAREFGIPTRDPEAAADVIVDGVADTVDLGRIKGADGTDRWFG TVMAAGFDSLVTDRTNRMRWPHGRMRYNLAMVAELSKLRLLPFRLSFDGDAEFDTELTLAAFGNTKSYGG GMKICPDADPRDGLLDATMVASASRTRLIRLFPTVFKGTHVNLDEVRTARARTITVDSPGINAYADGEYV CPLPVEVSAVPGALKILRPS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3762 | - | - | 100% (300) | diacylglycerol kinase |
| M. vanbaalenii PYR-1 | Mvan_0430 | - | 2e-09 | 25.16% (310) | phosphoesterase, PA-phosphatase related |
| M. vanbaalenii PYR-1 | Mvan_1783 | - | 3e-06 | 23.94% (330) | diacylglycerol kinase, catalytic region |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2276 | - | 1e-116 | 66.33% (294) | diacylglycerol kinase |
| M. gilvum PYR-GCK | Mflv_2771 | - | 1e-152 | 90.51% (295) | diacylglycerol kinase |
| M. tuberculosis H37Rv | Rv2252 | - | 1e-116 | 66.33% (294) | diacylglycerol kinase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3885 | - | 2e-81 | 53.45% (290) | hypothetical protein MAB_3885 |
| M. marinum M | MMAR_3345 | - | 1e-117 | 66.56% (299) | hypothetical protein MMAR_3345 |
| M. avium 104 | MAV_2184 | - | 1e-120 | 70.65% (293) | diacylglycerol kinase |
| M. smegmatis MC2 155 | MSMEG_4335 | - | 1e-127 | 76.37% (292) | diacylglycerol kinase |
| M. thermoresistible (build 8) | TH_1506 | - | 1e-139 | 80.61% (294) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_1297 | - | 1e-114 | 65.22% (299) | diacylglycerol kinase |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3762|M.vanbaalenii_PYR-1 ---------------MSPPARVTVLTNPTSGHGNAPHAAERAITRLHHRG
Mflv_2771|M.gilvum_PYR-GCK ---------------MT---RVTVLTNPASGHGSASHAAERAITRLHRRG
TH_1506|M.thermoresistible__bu ---------------VTVG-RITMLTNPASGHGSAPHAAERAAARFTARG
MSMEG_4335|M.smegmatis_MC2_155 ---------------MTG--RVTVLTNPMSGHGNAPHAAERAVVRLQQRG
Mb2276|M.bovis_AF2122/97 --------MSAGQLRRHEIGKVTALTNPLSGHGAAVKAAHGAIARLKHRG
Rv2252|M.tuberculosis_H37Rv --------MSAGQLRRHEIGKVTALTNPLSGHGAAVKAAHGAIARLKHRG
MMAR_3345|M.marinum_M MTPENPVNPLAGQLRQRSISKVTALTNPLSGHGAAVQAAQHAIARLHHRG
MUL_1297|M.ulcerans_Agy99 ---------MARQLRQRSISKVTALTNPLSGHGAAVQAAQHAIARLHHRG
MAV_2184|M.avium_104 ------MTSPAARLRRYEIGKVIALTNPASGHGAAVAAAQRAIARLHRRG
MAB_3885|M.abscessus_ATCC_1997 ------------------MTHLTVLTNPTAGHG-AAQAAEAAIAHLRARG
:: **** :*** * **. * .:: **
Mvan_3762|M.vanbaalenii_PYR-1 VDVVAIAGRDSSHARQLVEGALERGMDALVVVGGDGIISLALQVLAQTDI
Mflv_2771|M.gilvum_PYR-GCK VDVVAIAGRDAVHARQLVEGALERDMDALVVVGGDGIISLALQVLAQTDI
TH_1506|M.thermoresistible__bu VDVVAIAGRDADHARRLVEGALDHDMDALVVVGGDGVVSLALQVLAGTDV
MSMEG_4335|M.smegmatis_MC2_155 VDVTAIVGRDARHARELVREHLDRGTDALVVVGGDGVIGLALQELAGTDV
Mb2276|M.bovis_AF2122/97 VDVVEIVGGDAHDARHLLAAAVAKGTDAVMVTGGDGVVSNALQVLAGTDI
Rv2252|M.tuberculosis_H37Rv VDVVEIVGGDAHDARHLLAAAVAKGTDAVMVTGGDGVVSNALQVLAGTDI
MMAR_3345|M.marinum_M VEVIEIVGENAEDARYLLAAAVEKGTDAVVVTGGDGVISNALQVLAETDV
MUL_1297|M.ulcerans_Agy99 VEVIEIVGENAEDARYLLAAAVEKGTDAVVVTGGDGVISNALQVLAETDV
MAV_2184|M.avium_104 VEVVEIIGDDAQDARHLVGAALDKGADAVMVTGGDGVFSNALQVLAGTDI
MAB_3885|M.abscessus_ATCC_1997 LTVTHHAATSAAESHALAQEAARTGARGIVAAGGDGLVSIALQAVAATPV
: * . .: .:: * . .::..****:.. *** :* * :
Mvan_3762|M.vanbaalenii_PYR-1 PLGLVPAGTGNDHAREFGIPTRDPEAAADVIVDGVADTVDLGRIKGADG-
Mflv_2771|M.gilvum_PYR-GCK PLGVIPAGTGNDHAREFGIPTGDPEAAADVVVDGVSDHVDLGRISGADG-
TH_1506|M.thermoresistible__bu PLGIIPAGTGNDHAREFGIPTKDPEAAADVVVDGVTEVVDLGRIRGADG-
MSMEG_4335|M.smegmatis_MC2_155 PLGIVPAGTGNDHAREYRIPTGDPEAAADVIADGHTRTVDLGRIDADDG-
Mb2276|M.bovis_AF2122/97 PLGIIPAGTGNDHAREFGLPTKNPKAAADIVVDGWTETIDLGRIQDDNG-
Rv2252|M.tuberculosis_H37Rv PLGIIPAGTGNDHAREFGLPTKNPKAAADIVVDGWTETIDLGRIQDDNG-
MMAR_3345|M.marinum_M PLGIIPAGTGNDHAREFEIPTKDAEAAADIVVDGWTETIDLGRIQAGSGK
MUL_1297|M.ulcerans_Agy99 PLGIIPAGTGNDHAREFEIPTKDAEAAADIVVDGWTETIDLGPIQAGSGK
MAV_2184|M.avium_104 PAGIVPAGTGNDHAREFGIPTKDPEAAADIIVDGWAETVDLGRIRADNG-
MAB_3885|M.abscessus_ATCC_1997 ALGVIPIGTGNDCARMLDIPLSDPVAAAEVIAAGRIRVIDAGRIQYHGD-
. *::* ***** ** :* :. ***:::. * :* * * ..
Mvan_3762|M.vanbaalenii_PYR-1 --TDRWFGTVMAAGFDSLVTDRTNRMRWPHGRMRYNLAMVAELSKLRLLP
Mflv_2771|M.gilvum_PYR-GCK --TVRWFGTVMAAGFDSLVTDRTNRMRWPHGRMRYNLAMVAEISKLRLLP
TH_1506|M.thermoresistible__bu --TDKWFGTVLAAGFDSLVTDRTNRMRWPHGRMRYNLAVLAELSKLRLLP
MSMEG_4335|M.smegmatis_MC2_155 --TRRWFGTVVATGFDSLVSDRANRMSWPHGRMRYNLAMVAELSKLRLLP
Mb2276|M.bovis_AF2122/97 --IEKWFGTVAATGFDSLVNDRANRMRWPHGRMRYYIAMLAELSRLRPLP
Rv2252|M.tuberculosis_H37Rv --IEKWFGTVAATGFDSLVNDRANRMRWPHGRMRYYIAMLAELSRLRPLP
MMAR_3345|M.marinum_M DKCDKWFGTLAATGFDSLVTDRANRMTWPHGRLRYYIAMLVELSQLRPLP
MUL_1297|M.ulcerans_Agy99 DKCDKWFGTLAATGFDSLVTDRANRMTWPHGRLRYYIAMLVELSQLRPLP
MAV_2184|M.avium_104 --FDKWFGTVAATGFDSLVTDRANRMRWPHGRLRYYVAMLAELSQLRLLP
MAB_3885|M.abscessus_ATCC_1997 ---TTWFATVVASGFDSLVNDRANRMRWPRGRRRYDIAMALEAAKLRPLP
**.*: *:******.**:*** **:** ** :*: * ::** **
Mvan_3762|M.vanbaalenii_PYR-1 FRLSFDGDAEFDTELTLAAFGNTKSYGGGMKICPDADPRDGLLDATMVAS
Mflv_2771|M.gilvum_PYR-GCK FRLSFDGD-EISTQLTLAAFGNTRSYGGGMKICPGADPRDGLLDVTMVAS
TH_1506|M.thermoresistible__bu FRLTLDGR-EVQTMLTLAAVGNTRSYGGGMLICPNADPRDGLLDVTMIAT
MSMEG_4335|M.smegmatis_MC2_155 FRLSFDGGDAEDHALTMTAIGNTRSYGGGMLICPGADPTDGLLDITMIAS
Mb2276|M.bovis_AF2122/97 FRLVLDGTEEIVADLTLADFGNTRSYGGGLLICPNADHSDGLLDITMAQS
Rv2252|M.tuberculosis_H37Rv FRLVLDGTEEIVADLTLADFGNTRSYGGGLLICPNADHSDGLLDITMAQS
MMAR_3345|M.marinum_M FRLVLDGTEEIETDLTLATFGNTRSYGGGMLMCPNADRTDGLLDITMVRS
MUL_1297|M.ulcerans_Agy99 FRLVLDGTEEIETDLTLATFGNTRSYGGGMLMCPNADRTDDLLDITMVRS
MAV_2184|M.avium_104 FRLVLDGAREIDADITLAAFGNTRSYGGGMRICPAADHADGLLDITMVHE
MAB_3885|M.abscessus_ATCC_1997 FRIELDDQ-VIDTDVTLVAVGNGTSYGGGMRICPGAILDDGLLDITVVAA
**: :*. :*:. .** *****: :** * *.*** *:
Mvan_3762|M.vanbaalenii_PYR-1 ASRTRLIRLFPTVFKGTHVNLDEVRTARARTITVDSPGINAYADGEYVCP
Mflv_2771|M.gilvum_PYR-GCK ASRTRLIRLFPTVFKGTHVNLDEVSTRRARTITVDSPGINSYADGEYVCP
TH_1506|M.thermoresistible__bu ESRTRLIRLFPTVFKGTHVELDEVTTERVRTIGIDCPGINAYADGEYACP
MSMEG_4335|M.smegmatis_MC2_155 ASRSRLIRLFPTVFKGTHVNLDTVTTRRARSVRVECPGINAYADGDFAAP
Mb2276|M.bovis_AF2122/97 DSRTKLLRLFPTIFKGAHVELDEVSTTRAKTVHVECPGINVYADGDFACP
Rv2252|M.tuberculosis_H37Rv DSRTKLLRLFPTIFKGAHVELDEVSTTRAKTVHVECPGINVYADGDFACP
MMAR_3345|M.marinum_M GSRSRFLRLFPTVVKGTHVELDEVTTARAKSIDVECPGINVYADGDYACP
MUL_1297|M.ulcerans_Agy99 GPRSSFLRLFPTVVKGTHVELDEVTTARAKSIDVECPGINVYADGDYACP
MAV_2184|M.avium_104 ASRAKLVRLFPTVMKGTHVELEQVSTARAKSIHVECPGINVYADGDFACP
MAB_3885|M.abscessus_ATCC_1997 GGRLRLLRLSPTVYKGTHVDLPEVSTFRSRRVRLSAADITAYADGDPVAP
* ::** **: **:**:* * * * : : :....*. ****: ..*
Mvan_3762|M.vanbaalenii_PYR-1 LPVEVSAVPGALKILRPS--
Mflv_2771|M.gilvum_PYR-GCK LPVEVSAVPKALKILRPA--
TH_1506|M.thermoresistible__bu LPVEVSAVPGALRIRTPRR-
MSMEG_4335|M.smegmatis_MC2_155 LPATITAVPGALKILTSAPG
Mb2276|M.bovis_AF2122/97 LPAEISAVPAALQVLRPRHG
Rv2252|M.tuberculosis_H37Rv LPAEISAVPAALQVLRPRHG
MMAR_3345|M.marinum_M LPANISAVAGALQILRPNDR
MUL_1297|M.ulcerans_Agy99 LPANISAVAGALQILRPNDR
MAV_2184|M.avium_104 LPAEISAVPGALRILRAGP-
MAB_3885|M.abscessus_ATCC_1997 LPVDIDVVPGALSVFA----
**. : .*. ** :