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M. tuberculosis H37Rv Rv2235 (-)

annotation: PROBABLE CONSERVED TRANSMEMBRANE PROTEIN
coordinates: 2507637 - 2508452
length: 271

MPRLAFLLRPGWLALALVVVAFTYLCFTVLAPWQLGKNAKTSRENQQIRYSLDTPPVPLKTLLPQQDSSA
PDAQWRRVTATGQYLPDVQVLARLRVVEGDQAFEVLAPFVVDGGPTVLVDRGYVRPQVGSHVPPIPRLPV
QTVTITARLRDSEPSVAGKDPFVRDGFQQVYSINTGQVAALTGVQLAGSYLQLIEDQPGGLGVLGVPHLD
PGPFLSYGIQWISFGILAPIGLGYFAYAEIRARRREKAGSPPPDKPMTVEQKLADRYGRRR
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv2235--100% (271)PROBABLE CONSERVED TRANSMEMBRANE PROTEIN

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2259-1e-157100.00% (271) transmembrane protein
M. gilvum PYR-GCKMflv_2887-1e-10568.00% (275) putative transmembrane protein
M. leprae Br4923MLBr_01644-1e-11574.17% (271) hypothetical protein MLBr_01644
M. abscessus ATCC 19977MAB_1899c-2e-9363.97% (272) hypothetical protein MAB_1899c
M. marinum MMMAR_3310-1e-12980.66% (274) transmembrane protein
M. avium 104MAV_2204-1e-11674.28% (276) hypothetical protein MAV_2204
M. smegmatis MC2 155MSMEG_4311-1e-10669.06% (278) hypothetical protein MSMEG_4311
M. thermoresistible (build 8)TH_1462-1e-10768.68% (281) PROBABLE CONSERVED TRANSMEMBRANE PROTEIN
M. ulcerans Agy99MUL_1318-1e-13080.66% (274) transmembrane protein
M. vanbaalenii PYR-1Mvan_3623-1e-11069.29% (280) putative transmembrane protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2887|M.gilvum_PYR-GCK          --MTVRRWAFLLRPQWLALFVVVAAFAYLCFTVLAPWQLGKNTQTSRENA
Mvan_3623|M.vanbaalenii_PYR-1       ----MRRWAFLLRPQWLALFVVVLAFAYLCFTVLAPWQLGKNTKTSREND
MSMEG_4311|M.smegmatis_MC2_155      ----MRRLGFLLRPQWLALIVVVLAFAYLCFTVLAPWQLGKNTKTSRENS
TH_1462|M.thermoresistible__bu      ----MRRWAFLLRPSWLALIVVVLAFAYLCFTVLAPWQLGKNSKTSRENA
Rv2235|M.tuberculosis_H37Rv         ----MPRLAFLLRPGWLALALVVVAFTYLCFTVLAPWQLGKNAKTSRENQ
Mb2259|M.bovis_AF2122/97            ----MPRLAFLLRPGWLALALVVVAFTYLCFTVLAPWQLGKNAKTSRENQ
MMAR_3310|M.marinum_M               ----MRRLAFLLRPGWIALALVVIAFTYLCFTVLAPWQLGKNTKTSRENR
MUL_1318|M.ulcerans_Agy99           ----MRRLAFLLRPGWIALALVVIAFTYLCFTVLAPWQLGKNTKTSRENR
MLBr_01644|M.leprae_Br4923          ----MRHLALLLRPGWIALTLVVTAFTYLCFMVLAPWQLGKNTRMSRENN
MAV_2204|M.avium_104                MPRWLRGLSFLLRPGWVVLALVVVAFAYLCFTVLAPWQLGKHSRTSQQNH
MAB_1899c|M.abscessus_ATCC_199      ----MRRLAFLLRPGWIALALVVVAFAYLCFTVLAPWQLGKNTKTSRENN
                                        :   .:**** *:.* :** **:**** *********::: *::* 

Mflv_2887|M.gilvum_PYR-GCK          QISRSLGAEPLPVTSVLPHQDSAAPQEQWQRVTATGRYLPDAQVLARLRL
Mvan_3623|M.vanbaalenii_PYR-1       QISRSLDADPISVTTVLPEQDSAAPDEQWQQVTATGRYLPEAQVLARLRL
MSMEG_4311|M.smegmatis_MC2_155      QIANSLQAEPVPLTDILPHQDSTS-DDQWRRVTATGRYLPEGQVLARLRV
TH_1462|M.thermoresistible__bu      QIERSLTAEPVPVTTLLPEQDSAAPDEQWRRVTATGRYLPEAQVLARLRS
Rv2235|M.tuberculosis_H37Rv         QIRYSLDTPPVPLKTLLPQQDSSAPDAQWRRVTATGQYLPDVQVLARLRV
Mb2259|M.bovis_AF2122/97            QIRYSLDTPPVPLKTLLPQQDSSAPDAQWRRVTATGQYLPDVQVLARLRV
MMAR_3310|M.marinum_M               QINHALTSPAVPVKTLLPQQDSSAPEAQWRSVTATGHYLSDVQVLARLRV
MUL_1318|M.ulcerans_Agy99           QINHALSSPAVPVKTLLPQQDSSAPEAQWRSVTATGHYLSDVQVLARLRV
MLBr_01644|M.leprae_Br4923          QIEYSLNTPPVPVKTLLSHQDLSTSKSQWRQVTATGRYLPDVQVLARLRV
MAV_2204|M.avium_104                QIEHSLTTPPVPLKTLLPQQNSAAPAEQWRQVSATGHYLADVQVLARLRV
MAB_1899c|M.abscessus_ATCC_199      RIAQSVNADPVPLKNELRPDHSMPEDAEWRRVTATGHYLPDRQVLARLRV
                                    :*  :: : .:.:.  *  :.  .   :*: *:***:**.: ******* 

Mflv_2887|M.gilvum_PYR-GCK          IDGDPAFEVLVPFAVDGGPTVLVDRGYVRPVAGSQPPAIDAPPSETVTIT
Mvan_3623|M.vanbaalenii_PYR-1       IDGDPAFEVLVPFAVDGGPTVLVDRGYVRPIEGSKVPPIDALPTGTVTIT
MSMEG_4311|M.smegmatis_MC2_155      IEGEPAFEVLTPFAVEGGPTILVDRGYVRPVEGSGVPAIDPPPTDTVSIT
TH_1462|M.thermoresistible__bu      IGGEPAFEVLVPFAVDGGPTVLVDRGYVRPEQGR-VPDIPPVPREPVTIT
Rv2235|M.tuberculosis_H37Rv         VEGDQAFEVLAPFVVDGGPTVLVDRGYVRPQVGSHVPPIPRLPVQTVTIT
Mb2259|M.bovis_AF2122/97            VEGDQAFEVLAPFVVDGGPTVLVDRGYVRPQVGSHVPPIPRLPVQTVTIT
MMAR_3310|M.marinum_M               VDGDQAFEVLTPFAVDGGPTVLVDRGYVRPEPGSHVPPIPRAPDQTLTIT
MUL_1318|M.ulcerans_Agy99           VDGDQAFEVLTPFAVDGGPTVLVDRGYVRPEPGSHVPPIPRAPDQTLTIT
MLBr_01644|M.leprae_Br4923          VDSGQAFEVLAPFVVDDGPTVLVDRGYVRPEPGSHVPPIPRPPNEAVSIT
MAV_2204|M.avium_104                IDSKPAFEVLAPFVVDGGPTVLVDRGYVRPLEGSRVPPIPRPPADTVTIT
MAB_1899c|M.abscessus_ATCC_199      VDAKPAYEALTVFQVDDGPAILVNRGYVRPEQGTSVPPIPPAPAGQVTIN
                                    : .  *:*.*. * *:.**::**:******  *   * *   *   ::*.

Mflv_2887|M.gilvum_PYR-GCK          ARLRDSEGLARDKEPFQVDGVQQVYSININQISTLTGVPLVGSYLQLVDN
Mvan_3623|M.vanbaalenii_PYR-1       ARLRDSEGVARDKTPFEADGVKQVYSINTEQISSVTGVPLAGSYLQLVAD
MSMEG_4311|M.smegmatis_MC2_155      ARLRDSEAVATGKEPFRADGALQVYSINTGQVSQLTGTPLAGSYLQLVDN
TH_1462|M.thermoresistible__bu      ARLRDSEGVNPGREPFHGDGALQVYSINTAQIAELTGVPLTGSYLQLVGG
Rv2235|M.tuberculosis_H37Rv         ARLRDSEPSVAGKDPFVRDGFQQVYSINTGQVAALTGVQLAGSYLQLIED
Mb2259|M.bovis_AF2122/97            ARLRDSEPSVAGKDPFVRDGFQQVYSINTGQVAALTGVQLAGSYLQLIED
MMAR_3310|M.marinum_M               ARLRDFEPTMAGKEPFSRDGFEQVYSINAKQISTLTGVPLAGSYLQLVEN
MUL_1318|M.ulcerans_Agy99           ARLRDFEPTMAGKEPFSRDGFEQVYSINAKQISTLTGVPLAGSYLQLVEN
MLBr_01644|M.leprae_Br4923          ARLRDSEPVMKDKEPFSRDGVQQVYSINIEQVARLTKIPLAGSYLQLVDN
MAV_2204|M.avium_104                ARLRNSEPAAAGKDPFVGDGVRQVYSIDTEQIAVLTKVPLAGSYLQLVDG
MAB_1899c|M.abscessus_ATCC_199      ARLREPEQ-QSEKSPFLENGQYQVYSIVPVQVSTLVKIPLAGPYLQLSEG
                                    ****: *     : **  :*  *****   *:: :.   *.*.****  .

Mflv_2887|M.gilvum_PYR-GCK          QPGGLGVIPLPHLDAGPFLSYGIQWIAFGIIAPIGVGYFVYSEIKVRRRE
Mvan_3623|M.vanbaalenii_PYR-1       QPGGLGVIPLPHLDAGPFLSYGIQWIAFGIIAPIGVGYFVYSEIRVRRRE
MSMEG_4311|M.smegmatis_MC2_155      QPGGLGAIPLPHLDAGPFLSYGIQWIAFGIIAPIGLGYFMYAEIQQRRRE
TH_1462|M.thermoresistible__bu      QPGGLGEIELPHLDAGPFLSYGIQWIAFGIIAPIGLGYFVWAEVQQRRRE
Rv2235|M.tuberculosis_H37Rv         QPGGLGVLGVPHLDPGPFLSYGIQWISFGILAPIGLGYFAYAEIRARRRE
Mb2259|M.bovis_AF2122/97            QPGGLGVLGVPHLDPGPFLSYGIQWISFGILAPIGLGYFAYAEIRARRRE
MMAR_3310|M.marinum_M               QPGGLGLIGLPHLDSGPFLSYGIQWIAFGILAPIGLGYFAYAELRARRRE
MUL_1318|M.ulcerans_Agy99           QPGGLGLIGLPHLDSGPFLSYGIQWIAFGILAPIGLGYFAYAELRARRRE
MLBr_01644|M.leprae_Br4923          QPGGLGVIDIPHLDAGPFLSYGIQWISFGIIAPIGLGYLAYAEIRTHRQE
MAV_2204|M.avium_104                QPGGLGVVGVPQLDAGPFLSYGIQWIAFGILAPIGVGYFAYSELRARRAE
MAB_1899c|M.abscessus_ATCC_199      QPGGLGAIPLPQLDAGPFLSYGIQWIAFGILAPIGLGYFVFSEIRQRRAA
                                    ****** : :*:**.***********:***:****:**: ::*:: :*  

Mflv_2887|M.gilvum_PYR-GCK          KALAA--AAAES---AEAGAAPTTEQKLADRYGKRR
Mvan_3623|M.vanbaalenii_PYR-1       KALAD--AASSESSGDEPAAPLSTEQKLADRYGKRR
MSMEG_4311|M.smegmatis_MC2_155      RAAQAKKDAAGPR----PAAELTPEEKLADRYGKRR
TH_1462|M.thermoresistible__bu      KAAQQDRAQADIRGDAAAGKPLTAEEKLADRYGRR-
Rv2235|M.tuberculosis_H37Rv         ---KAGSPPPDK--------PMTVEQKLADRYGRRR
Mb2259|M.bovis_AF2122/97            ---KAGSPPPDK--------PMTVEQKLADRYGRRR
MMAR_3310|M.marinum_M               TRAREDAPPADT--------PMTVEQKLADRYGRRR
MUL_1318|M.ulcerans_Agy99           TRAREDAPPADT--------PMTVEQKLADRYGRRR
MLBr_01644|M.leprae_Br4923          ----KLAKPSQA--------PMAVEEKLADRYGHPR
MAV_2204|M.avium_104                K--QPAAPAAEA--------PQSVQDKLADRYGRRR
MAB_1899c|M.abscessus_ATCC_199      AAAVKAVKPGTP---------QTTEERLADRYGRR-
                                                          : :::******: