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VTTEPGYLSPSVAVATSMPKRGVGAAVLIVPVVSTGEEDRPGAVVASAEPFLRADTVAEIEAGLRALDAT GASDQVHRLAVPSLPVGSVLTVGLGKPRREWPADTIRCAAGVAARALNSSEAVITTLAELPGDGICSATV EGLILGSYRFSAFRSDKTAPKDAGLRKITVLCCAKDAKKRALHGAAVATAVATARDLVNTPPSHLFPAEF AKRAKTLSESVGLDVEVIDEKALKKAGYGGVIGVGQGSSRPPRLVRLIHRGSRLAKNPQKAKKVALVGKG ITFDTGGISIKPAASMHHMTSDMGGAAAVIATVTLAARLRLPIDVIATVPMAENMPSATAQRPGDVLTQY GGTTVEVLNTDAEGRLILADAIVRACEDKPDYLIETSTLTGAQTVALGTRIPGVMGSDEFRDRVAAISQR VGENGWPMPLPDDLKDDLKSTVADLANVSGQRFAGMLVAGVFLREFVAESVDWAHIDVAGPAYNTGSAWG YTPKGATGVPTRTMFAVLEDIAKNG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2213 | pepB | - | 100% (515) | leucyl aminopeptidase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2236 | pepB | 0.0 | 99.81% (515) | leucyl aminopeptidase |
| M. gilvum PYR-GCK | Mflv_2938 | - | 0.0 | 71.54% (520) | leucyl aminopeptidase |
| M. leprae Br4923 | MLBr_00864 | pepA | 0.0 | 83.14% (522) | leucyl aminopeptidase |
| M. abscessus ATCC 19977 | MAB_1948c | - | 0.0 | 68.10% (511) | cytosol aminopeptidase (leucyl aminopeptidase) |
| M. marinum M | MMAR_3258 | pepB | 0.0 | 84.97% (519) | leucyl aminopeptidase PepB |
| M. avium 104 | MAV_2279 | - | 0.0 | 83.30% (515) | leucyl aminopeptidase |
| M. smegmatis MC2 155 | MSMEG_4281 | - | 0.0 | 72.61% (522) | leucyl aminopeptidase |
| M. thermoresistible (build 8) | TH_1297 | pepB | 0.0 | 70.67% (508) | Probable aminopeptidase PepB |
| M. ulcerans Agy99 | MUL_3573 | pepB | 0.0 | 84.97% (519) | leucyl aminopeptidase |
| M. vanbaalenii PYR-1 | Mvan_3575 | - | 0.0 | 73.99% (519) | leucyl aminopeptidase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2938|M.gilvum_PYR-GCK ---MSTSVGHQPPAVAVAGALPKRPVQSSVLIVPVVSGD-DGN-----GA
Mvan_3575|M.vanbaalenii_PYR-1 ---MSTSAGYQSPVVTVASALPKRRVDSSVLIVPVVSGG-DGEEGSEARA
Rv2213|M.tuberculosis_H37Rv ---MTTEPGYLSPSVAVATSMPKRGVGAAVLIVPVVSTG-EED----RPG
Mb2236|M.bovis_AF2122/97 ---MTTEPGYLSPSVAVATSMPKRGVGAAVLIVPVVSTG-EED----RPG
MMAR_3258|M.marinum_M ---MTAESGDQIPTVHVATSLPKRGVSSSVLIVPVVSTG-DDEQSGERPG
MUL_3573|M.ulcerans_Agy99 ---MTAESGDQIPTVHVATSLPKRRVSSSVLIVPVVSTG-DDEQSGERPG
MLBr_00864|M.leprae_Br4923 -MPVTTDPGYQGPSVHVAASLPKHDVSSSVLIVPVVSAS-DSDESEDRPG
MAV_2279|M.avium_104 MMRMSTEPGYASPVVNVASSLPRRAAASTVLIVPVVSTG-DDD----KPG
TH_1297|M.thermoresistible__bu --------------VTVSTSLPSSGVDEAVLIIPVVKAE-NGDDP-DTGT
MSMEG_4281|M.smegmatis_MC2_155 -MRVSNAPGYQAPTVTVSSSLPRRGVAEAVLVVGVVSNDSNNKRSDTDSA
MAB_1948c|M.abscessus_ATCC_199 ------MSAYTAPSFTLATSIPQRGVSAAVLLVGVRPSDKDSD------K
. :: ::* . :**:: * : .
Mflv_2938|M.gilvum_PYR-GCK TVVG--NPYLDAEATGEIEVALRALGAKGGNEQLTRVVVPALPVSSVLAV
Mvan_3575|M.vanbaalenii_PYR-1 AVVA--GPHLDADAVAEIEAALQALGAKGGSEQLTRVVVPALPVTSVLAV
Rv2213|M.tuberculosis_H37Rv AVVASAEPFLRADTVAEIEAGLRALDATGASDQVHRLAVPSLPVGSVLTV
Mb2236|M.bovis_AF2122/97 AVVASAEPFLRADTVAEIEAGLRALDATGASDQVHRLAVPSLPVGSVLTV
MMAR_3258|M.marinum_M AVVASAEPFLSADAIAEIEAGLRALDATGASDQVHRLVVSSLPVSSVLTV
MUL_3573|M.ulcerans_Agy99 AVVASAEPFLSADAIAEIEAGLRALDATGASDQVHRLVVSSLPVSSVLTV
MLBr_00864|M.leprae_Br4923 AVVAAAEPFLTAAAVAEIEAGLRALEATGGSDQVHRLVAPSLPVGSVLTV
MAV_2279|M.avium_104 AVVAPAGSFLSSDAVAEIESGLRALAATGGAEQLHRLVVGSLPVSSVLTV
TH_1297|M.thermoresistible__bu PAVLAADRYLPDAAVGAIESALTAVGGTGAEGQVHRLVIDSLPVASVLTI
MSMEG_4281|M.smegmatis_MC2_155 PKLLTPAPFFDATVVTAIESGLRALGATGGEGQTHRLVVDALPVGSVLAV
MAB_1948c|M.abscessus_ATCC_199 SPRVVDAQLLDKAAVKSIEAALTAVGATGSAEQLTRVVVDGLPVASVLAV
. : . ** .* *: ..*. * *:. .*** ***::
Mflv_2938|M.gilvum_PYR-GCK GLGKSRDEWSAETIRRAAGAAARSLS-GVENVFTTLSDLDLEA-------
Mvan_3575|M.vanbaalenii_PYR-1 GLGKSRDDWSAETIRRAAGAAARSLS-GVEHVITTLSDLDLEA-------
Rv2213|M.tuberculosis_H37Rv GLGKPRREWPADTIRCAAGVAARALN-SSEAVITTLAELPGDG---ICSA
Mb2236|M.bovis_AF2122/97 GLGKPRREWPADTIRCAAGVAARALN-SSEAVITTLAELPGDG---ICSA
MMAR_3258|M.marinum_M GLGKPRYEWTPDAVRRAAGAAARALG-TAKTVVTTLADLPGDG---VCAA
MUL_3573|M.ulcerans_Agy99 GLGKPRYEWTPDAVRRAAGAAARALG-TAKAVVTTLADLPGDG---VCAA
MLBr_00864|M.leprae_Br4923 SLGKPRSEWPADTIRRAAGVAARSLG-RAEVVITTLAELPGESGASICSA
MAV_2279|M.avium_104 GLGKPRSEWPADTVRRAAGVAARSLS-NTETVFTTLAALPGEG---VASA
TH_1297|M.thermoresistible__bu GMGSRRDEWPADVVRRAAGTAARSLD-KTAAAVTTLSAVDLEA-------
MSMEG_4281|M.smegmatis_MC2_155 GLGKDRDEWPADVIRRAAGNAARALDGKVATVITTLSASGPQA----LSA
MAB_1948c|M.abscessus_ATCC_199 GLGKADD---AETIRRAAAVAARSLD-NVEILVTTLSERDVDA-------
.:*. .:.:* **. ***:*. .***: :.
Mflv_2938|M.gilvum_PYR-GCK AIEGLLLGAYRFTEFRSAKTAPTDAGIRKVTALTPDTRSATKDAAARAEA
Mvan_3575|M.vanbaalenii_PYR-1 TIEGLVLGAYRFSEFRSEKTAPKDAGVRKITVLAPDTKAATKDAAAHAEA
Rv2213|M.tuberculosis_H37Rv TVEGLILGSYRFSAFRSDKTAPKDAGLRKITVLCCAKDAK-KRALHGAA-
Mb2236|M.bovis_AF2122/97 TVEGLILGSYRFSAFRSDKTAPKDAGLRKITVLCCAKDAK-KRALHGAA-
MMAR_3258|M.marinum_M AIEGLILGSYRFSAFRSAKTAPKDAGLHKVTVLTTAKDAR-KHCAHGAA-
MUL_3573|M.ulcerans_Agy99 AVEGLILGSYRFSAFRSAKTAPKDAGLHKITVLTTTKDAR-KHCAHGAA-
MLBr_00864|M.leprae_Br4923 VVEGLMLGSYRFTDFRSRKTAPKDNGLRKITVLANAKDAK-KQSAHGAT-
MAV_2279|M.avium_104 AVEGLILGSYRFTEFRSAKTAPKDKGLQKITVLATAKDAK-QEVAHGAA-
TH_1297|M.thermoresistible__bu TVEGLIMGAYRFTEFRSDKTAPKDDGLRSVTVLTSEADAA-ESAVRRATQ
MSMEG_4281|M.smegmatis_MC2_155 AVEGLILGAYRFSDFRSEKTAPKGPGLTAITVLAHDTKAPTKAEAQRGVD
MAB_1948c|M.abscessus_ATCC_199 TVQGLVLGGYRFAEFRSAKTAPKDAGLQKVTLLVGDKGRAQKEAMERGAA
.::**::*.***: *** ****.. *: :* * : .
Mflv_2938|M.gilvum_PYR-GCK IAVAVATARDFVNTPPSHLFPAEFAERAKTLGEQAGLEVKILDEKALARD
Mvan_3575|M.vanbaalenii_PYR-1 VAAAVATARDFVNTPPSHLFPVEFAKRAKALGEAAGLQVEVLDEKALARD
Rv2213|M.tuberculosis_H37Rv VATAVATARDLVNTPPSHLFPAEFAKRAKTLSESVGLDVEVIDEKALKKA
Mb2236|M.bovis_AF2122/97 VATAVATARDLVNTPPSHLFPAELAKRAKTLSESVGLDVEVIDEKALKKA
MMAR_3258|M.marinum_M VATAVATARDLVNTPPSHLYPAELARRAKVLGESVGLEVQVLDEKALQKA
MUL_3573|M.ulcerans_Agy99 VATAVATARDLVNTPPSHLYPAELARRAKVLGESVGLEVQVLDEKALQKA
MLBr_00864|M.leprae_Br4923 VASAVATARDLVNTPPSHLFPAEFAKCAKTLGESAGLEVEVLDDKALQKA
MAV_2279|M.avium_104 VATAVATARDLVNTPPSHLFPDEFAKRARALGESVGLEVEVIDEKALQKG
TH_1297|M.thermoresistible__bu VASAVAIARDFVNTPPSHLYPDEFARRAKALGESAGLTVEVLDEKALAEA
MSMEG_4281|M.smegmatis_MC2_155 IATAVATARDFVNTPPSHLFPDEFAKRAKAFGESVGLKVEVLDDKALEKA
MAB_1948c|M.abscessus_ATCC_199 VATAVVTARDFVNTPPSHLFPAEFAKRAKALATAEGIEVEVLDEKELAKG
:* **. ***:********:* *:*. *:.:. *: *:::*:* * .
Mflv_2938|M.gilvum_PYR-GCK GYGGIIGVGKGSSRPPRLVRLAHRGG-----GRKGKKVALVGKGITFDTG
Mvan_3575|M.vanbaalenii_PYR-1 GYGGIVGVGKGSSRPPRLVRLAHLGG-----GRKGKKVALVGKGITFDTG
Rv2213|M.tuberculosis_H37Rv GYGGVIGVGQGSSRPPRLVRLIHRGSRLAKNPQKAKKVALVGKGITFDTG
Mb2236|M.bovis_AF2122/97 GYGGVIGVGQGSSRPPRLVRLIHRGSRLAKNPQKAKKVALVGKGITFDTG
MMAR_3258|M.marinum_M GYGGLVGVGQGSSRPPRLVRLTHRGSRLAKNPRRAKKVALVGKGVTFDTG
MUL_3573|M.ulcerans_Agy99 GYGGLVGVGQGSSRPPRLVRLTHRGSRLAKNPRRAKKVALVGKGVTFDTG
MLBr_00864|M.leprae_Br4923 GYGGVIGVGQGSSRTPRLVRLIHQGSRLAKNPKNARKVALVGKGITFDTG
MAV_2279|M.avium_104 GYGGILGVGQGSSRPPRLVRLIHRGSRLAKKSKQAKKVALVGKGVTFDTG
TH_1297|M.thermoresistible__bu GYGGIVGVGQGSSRPPRLVRLTHRGG----DGENRKKVALVGKGITFDTG
MSMEG_4281|M.smegmatis_MC2_155 GYGGIIGVGKGSSRPPRLVRLSHLGAK-----RKGKRVALVGKGITFDTG
MAB_1948c|M.abscessus_ATCC_199 GYGGIVGVGKGSSRPPRLVRLTYRGAK----GKKAKSVALVGKGITFDTG
****::***:****.****** : *. .. : *******:*****
Mflv_2938|M.gilvum_PYR-GCK GISIKPAANMHHMTSDMGGAAAVIATVVLAARQKLPIDVVAYVPMAENMP
Mvan_3575|M.vanbaalenii_PYR-1 GISIKPAANMHHMTSDMGGAAAVIATVLLAARRRLPIDVVAYVPMAENMP
Rv2213|M.tuberculosis_H37Rv GISIKPAASMHHMTSDMGGAAAVIATVTLAARLRLPIDVIATVPMAENMP
Mb2236|M.bovis_AF2122/97 GISIKPAASMHHMTSDMGGAAAVIATVTLAARLRLPIDVIATVPMAENMP
MMAR_3258|M.marinum_M GISIKPAASMHYMTSDMGGAAAVIATVALAAQLELPIDVIATVPIAENMP
MUL_3573|M.ulcerans_Agy99 GISIKPAASMHYMTSDMGGAAAVIATVALAAQLELPINVIATVPIAENMP
MLBr_00864|M.leprae_Br4923 GISIKPAASMHHMTSDMAGAAAVIATITLAAQLKLPIDVVATVPMAENMP
MAV_2279|M.avium_104 GISIKPAASMHHMTSDMGGAAAVIATVALAARLQLPIDVIATVPMAENMP
TH_1297|M.thermoresistible__bu GISIKPAANMHHMTSDMSGAAAVIATMVLVAQQQLPIDVIATVPMAENMP
MSMEG_4281|M.smegmatis_MC2_155 GISIKPAANMHHMTSDMGGAAAVIATVALAAVRQLPIDVIATVPMAENMP
MAB_1948c|M.abscessus_ATCC_199 GISIKPAGGMENMTSDMGGAAAVIAVTLLAARQQLPIDVIATVPMAENMP
*******..*. *****.*******. *.* .***:*:* **:*****
Mflv_2938|M.gilvum_PYR-GCK SSTAQRPGDVLTQYGGITVEVLNTDAEGRLVLADAIVRACEDNPDYLIET
Mvan_3575|M.vanbaalenii_PYR-1 SATAQRPGDVLTQYGGITVEVLNTDAEGRLILADAIARACEDAPDYLIET
Rv2213|M.tuberculosis_H37Rv SATAQRPGDVLTQYGGTTVEVLNTDAEGRLILADAIVRACEDKPDYLIET
Mb2236|M.bovis_AF2122/97 SATAQRPGDVLTQYGGTTVEVLNTDAEGRLILADAIVRACEDKPDYLIET
MMAR_3258|M.marinum_M SATAQRPGDVLTQYGGTTVEVLNTDAEGRLILADAIVRACEDNPDYLIET
MUL_3573|M.ulcerans_Agy99 SATAQRPGDVLTQYGGTTVEVLNTDAEGRLILADAIVRACEDNPDYLIET
MLBr_00864|M.leprae_Br4923 SGTAQRPGDVLTQYGGITVEVLNTDAEGRLILADAIVRACQDNPDYLIET
MAV_2279|M.avium_104 SGTAQRPGDVLTQYGGTTVEVQNTDAEGRLILADAIVRACEDNPDYLIET
TH_1297|M.thermoresistible__bu SATAQRPGDVLTQYGGTTVEVLNTDAEGRLILADAIVRACEDEPDYLIET
MSMEG_4281|M.smegmatis_MC2_155 SATAQRPGDVLTQYGGITVEVLNTDAEGRLILADAIVRACEDNPDYLIET
MAB_1948c|M.abscessus_ATCC_199 SSTAQRPGDVLTQLDGTTVEVINTDAEGRLILADAIVRACRDQPDYLIDT
*.*********** .* **** ********:*****.***.* *****:*
Mflv_2938|M.gilvum_PYR-GCK STLTGAQTVALGSRTPGVMGSDEFRDRVAEISQEVGENAWAMPLPEELKD
Mvan_3575|M.vanbaalenii_PYR-1 STLTGAQTVALGARTPGVMGSDDFRDRVAGISQAVGENGWAMPLPEELKD
Rv2213|M.tuberculosis_H37Rv STLTGAQTVALGTRIPGVMGSDEFRDRVAAISQRVGENGWPMPLPDDLKD
Mb2236|M.bovis_AF2122/97 STLTGAQTVALGTRIPGVMGSDEFRDRVAAISQRVGENGWPMPLPDDLKD
MMAR_3258|M.marinum_M STLTGAQTVALGARIPGVMGSDEFRDRVAAISQQVGENGWPMPLPDELKD
MUL_3573|M.ulcerans_Agy99 STLTGAQTVALGARIPGVMGSDEFRDRVAAISQQVGENGWPMPLPDELKD
MLBr_00864|M.leprae_Br4923 STLTGAQTVALGSRIPGVMGSDKFRDRVAKTSQQVGENGWPMPLPDELKD
MAV_2279|M.avium_104 STLTGAQTVALGARIPGVMGSDEFRDRVAAISQRVGENGWPMPLPDELKE
TH_1297|M.thermoresistible__bu STLTGAQTIALGARTPGVMGSDEFRDRVAALSQRVGENGWAMPLPEELKE
MSMEG_4281|M.smegmatis_MC2_155 STLTGAQTVALGARTPGVMGSDEFRDRVAKLSQDVGENGWPMPLPEELRD
MAB_1948c|M.abscessus_ATCC_199 ATLTGAQVVALGTRTPGVMGTDEFRDRVSAISQSVGENGWAMPLPEELRD
:******.:***:* *****:*.*****: ** ****.*.****::*::
Mflv_2938|M.gilvum_PYR-GCK DLKSTVADLANVSGSRFAGMLVAGTYLREFVADGVEWAHIDIAAPAYNSG
Mvan_3575|M.vanbaalenii_PYR-1 DLKSTVADLANVSGSRFAGMLVAGTYLREFVADGVEWAHIDVAAPAYNSG
Rv2213|M.tuberculosis_H37Rv DLKSTVADLANVSGQRFAGMLVAGVFLREFVAESVDWAHIDVAGPAYNTG
Mb2236|M.bovis_AF2122/97 DLKSTVADLANVSGQRFAGMLVAGVFLREFVAESVDWAHIDVAGPAYNTG
MMAR_3258|M.marinum_M DLKSTVADLANVSGQRFAGMLVAGVFLREFVADAVDWAHIDVAGPAYNTG
MUL_3573|M.ulcerans_Agy99 DLKSTVADLANVSGQRFAGMLVAGVFLREFVADAVDWAHIDVAGPAYNTG
MLBr_00864|M.leprae_Br4923 DLKSTVADLANVSGQRFAGMLVAGAFLREFVADGVDWAHIDIAGPAYNTD
MAV_2279|M.avium_104 DLKSTVADLSNISGQRFAGMLVAGVFLREFVADGVGWAHIDVAGPAYNTG
TH_1297|M.thermoresistible__bu ELKSTVADLANVGSSRYAGMLLAGAFLREFVADGVQWAHIDIAAPAYNTG
MSMEG_4281|M.smegmatis_MC2_155 DLKSTVADLANVSGSRFAGMLVAGTYLREFVAEGVQWAHIDVAAPAYNTG
MAB_1948c|M.abscessus_ATCC_199 DLKSRVADLANVTNHRNGGMLAAGQYLREFVADGVQWAHIDVAGPAYNTG
:*** ****:*: . * .*** ** :******:.* *****:*.****:.
Mflv_2938|M.gilvum_PYR-GCK GPWGYTPKGGTGVPTRTMFAVLEDIAANG
Mvan_3575|M.vanbaalenii_PYR-1 GPWGYTPKGGTGVPTRTMFAVLEDIAANG
Rv2213|M.tuberculosis_H37Rv SAWGYTPKGATGVPTRTMFAVLEDIAKNG
Mb2236|M.bovis_AF2122/97 SAWGYTPKGATGVPTRTMFAVLEDIAKNG
MMAR_3258|M.marinum_M SAWGYTPKGATGVPTRTMFAVLEDIAANG
MUL_3573|M.ulcerans_Agy99 SAWGYTPKGATGVPTRTMFAVLEDIAANG
MLBr_00864|M.leprae_Br4923 SPWGYTPKGATGVPTRTMFAMLEDIANHG
MAV_2279|M.avium_104 SPWGYSPKGATGVPTRTMFAVLEDIAANG
TH_1297|M.thermoresistible__bu SPWGYTPKGGTGVPTRTLFAVLKDICRNG
MSMEG_4281|M.smegmatis_MC2_155 GPWGYTPKGGTGVPARTMFAVLEDIAANG
MAB_1948c|M.abscessus_ATCC_199 GPWGYTPKGGTGVPVRTIFGVLEDIAANG
..***:***.****.**:*.:*:**. :*