For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. abscessus ATCC 19977 MAB_1948c (-)

annotation: cytosol aminopeptidase (leucyl aminopeptidase)
coordinates: 1945756 - 1947264
length: 502

SAYTAPSFTLATSIPQRGVSAAVLLVGVRPSDKDSDKSPRVVDAQLLDKAAVKSIEAALTAVGATGSAEQ
LTRVVVDGLPVASVLAVGLGKADDAETIRRAAAVAARSLDNVEILVTTLSERDVDATVQGLVLGGYRFAE
FRSAKTAPKDAGLQKVTLLVGDKGRAQKEAMERGAAVATAVVTARDFVNTPPSHLFPAEFAKRAKALATA
EGIEVEVLDEKELAKGGYGGIVGVGKGSSRPPRLVRLTYRGAKGKKAKSVALVGKGITFDTGGISIKPAG
GMENMTSDMGGAAAVIAVTLLAARQQLPIDVIATVPMAENMPSSTAQRPGDVLTQLDGTTVEVINTDAEG
RLILADAIVRACRDQPDYLIDTATLTGAQVVALGTRTPGVMGTDEFRDRVSAISQSVGENGWAMPLPEEL
RDDLKSRVADLANVTNHRNGGMLAAGQYLREFVADGVQWAHIDVAGPAYNTGGPWGYTPKGGTGVPVRTI
FGVLEDIAANG*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. abscessus ATCC 19977MAB_1948c--100% (502)cytosol aminopeptidase (leucyl aminopeptidase)

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2236pepB0.067.91% (511) leucyl aminopeptidase
M. gilvum PYR-GCKMflv_2938-0.070.94% (499) leucyl aminopeptidase
M. tuberculosis H37RvRv2213pepB0.068.10% (511) leucyl aminopeptidase
M. leprae Br4923MLBr_00864pepA1e-18064.29% (518) leucyl aminopeptidase
M. marinum MMMAR_3258pepB0.066.60% (512) leucyl aminopeptidase PepB
M. avium 104MAV_2279-0.069.14% (512) leucyl aminopeptidase
M. smegmatis MC2 155MSMEG_4281-0.068.95% (512) leucyl aminopeptidase
M. thermoresistible (build 8)TH_1297pepB0.068.40% (500) Probable aminopeptidase PepB
M. ulcerans Agy99MUL_3573pepB0.066.21% (512) leucyl aminopeptidase
M. vanbaalenii PYR-1Mvan_3575-0.071.40% (507) leucyl aminopeptidase

CLUSTAL 2.0.9 multiple sequence alignment


Mb2236|M.bovis_AF2122/97            ---MTTEPGYLSPSVAVATSMPKRGVGAAVLIVPVVSTG-EED----RPG
Rv2213|M.tuberculosis_H37Rv         ---MTTEPGYLSPSVAVATSMPKRGVGAAVLIVPVVSTG-EED----RPG
MMAR_3258|M.marinum_M               ---MTAESGDQIPTVHVATSLPKRGVSSSVLIVPVVSTG-DDEQSGERPG
MUL_3573|M.ulcerans_Agy99           ---MTAESGDQIPTVHVATSLPKRRVSSSVLIVPVVSTG-DDEQSGERPG
MLBr_00864|M.leprae_Br4923          -MPVTTDPGYQGPSVHVAASLPKHDVSSSVLIVPVVSAS-DSDESEDRPG
MAV_2279|M.avium_104                MMRMSTEPGYASPVVNVASSLPRRAAASTVLIVPVVSTG-DDD----KPG
TH_1297|M.thermoresistible__bu      --------------VTVSTSLPSSGVDEAVLIIPVVKAE-NGDDP-DTGT
MSMEG_4281|M.smegmatis_MC2_155      -MRVSNAPGYQAPTVTVSSSLPRRGVAEAVLVVGVVSNDSNNKRSDTDSA
Mflv_2938|M.gilvum_PYR-GCK          ---MSTSVGHQPPAVAVAGALPKRPVQSSVLIVPVVSGD-DGN-----GA
Mvan_3575|M.vanbaalenii_PYR-1       ---MSTSAGYQSPVVTVASALPKRRVDSSVLIVPVVSGG-DGEEGSEARA
MAB_1948c|M.abscessus_ATCC_199      ------MSAYTAPSFTLATSIPQRGVSAAVLLVGVRPSDKDSD------K
                                                  . :: ::*   .  :**:: *     : .       

Mb2236|M.bovis_AF2122/97            AVVASAEPFLRADTVAEIEAGLRALDATGASDQVHRLAVPSLPVGSVLTV
Rv2213|M.tuberculosis_H37Rv         AVVASAEPFLRADTVAEIEAGLRALDATGASDQVHRLAVPSLPVGSVLTV
MMAR_3258|M.marinum_M               AVVASAEPFLSADAIAEIEAGLRALDATGASDQVHRLVVSSLPVSSVLTV
MUL_3573|M.ulcerans_Agy99           AVVASAEPFLSADAIAEIEAGLRALDATGASDQVHRLVVSSLPVSSVLTV
MLBr_00864|M.leprae_Br4923          AVVAAAEPFLTAAAVAEIEAGLRALEATGGSDQVHRLVAPSLPVGSVLTV
MAV_2279|M.avium_104                AVVAPAGSFLSSDAVAEIESGLRALAATGGAEQLHRLVVGSLPVSSVLTV
TH_1297|M.thermoresistible__bu      PAVLAADRYLPDAAVGAIESALTAVGGTGAEGQVHRLVIDSLPVASVLTI
MSMEG_4281|M.smegmatis_MC2_155      PKLLTPAPFFDATVVTAIESGLRALGATGGEGQTHRLVVDALPVGSVLAV
Mflv_2938|M.gilvum_PYR-GCK          TVVG--NPYLDAEATGEIEVALRALGAKGGNEQLTRVVVPALPVSSVLAV
Mvan_3575|M.vanbaalenii_PYR-1       AVVA--GPHLDADAVAEIEAALQALGAKGGSEQLTRVVVPALPVTSVLAV
MAB_1948c|M.abscessus_ATCC_199      SPRVVDAQLLDKAAVKSIEAALTAVGATGSAEQLTRVVVDGLPVASVLAV
                                    .        :   .   ** .* *: ..*.  *  *:.  .*** ***::

Mb2236|M.bovis_AF2122/97            GLGKPRREWPADTIRCAAGVAARALN-SSEAVITTLAELPGDG---ICSA
Rv2213|M.tuberculosis_H37Rv         GLGKPRREWPADTIRCAAGVAARALN-SSEAVITTLAELPGDG---ICSA
MMAR_3258|M.marinum_M               GLGKPRYEWTPDAVRRAAGAAARALG-TAKTVVTTLADLPGDG---VCAA
MUL_3573|M.ulcerans_Agy99           GLGKPRYEWTPDAVRRAAGAAARALG-TAKAVVTTLADLPGDG---VCAA
MLBr_00864|M.leprae_Br4923          SLGKPRSEWPADTIRRAAGVAARSLG-RAEVVITTLAELPGESGASICSA
MAV_2279|M.avium_104                GLGKPRSEWPADTVRRAAGVAARSLS-NTETVFTTLAALPGEG---VASA
TH_1297|M.thermoresistible__bu      GMGSRRDEWPADVVRRAAGTAARSLD-KTAAAVTTLSAVDLEA-------
MSMEG_4281|M.smegmatis_MC2_155      GLGKDRDEWPADVIRRAAGNAARALDGKVATVITTLSASGPQA----LSA
Mflv_2938|M.gilvum_PYR-GCK          GLGKSRDEWSAETIRRAAGAAARSLS-GVENVFTTLSDLDLEA-------
Mvan_3575|M.vanbaalenii_PYR-1       GLGKSRDDWSAETIRRAAGAAARSLS-GVEHVITTLSDLDLEA-------
MAB_1948c|M.abscessus_ATCC_199      GLGKADD---AETIRRAAAVAARSLD-NVEILVTTLSERDVDA-------
                                    .:*.      .:.:* **. ***:*.      .***:    :.       

Mb2236|M.bovis_AF2122/97            TVEGLILGSYRFSAFRSDKTAPKDAGLRKITVLCCAKDAK-KRALHGAA-
Rv2213|M.tuberculosis_H37Rv         TVEGLILGSYRFSAFRSDKTAPKDAGLRKITVLCCAKDAK-KRALHGAA-
MMAR_3258|M.marinum_M               AIEGLILGSYRFSAFRSAKTAPKDAGLHKVTVLTTAKDAR-KHCAHGAA-
MUL_3573|M.ulcerans_Agy99           AVEGLILGSYRFSAFRSAKTAPKDAGLHKITVLTTTKDAR-KHCAHGAA-
MLBr_00864|M.leprae_Br4923          VVEGLMLGSYRFTDFRSRKTAPKDNGLRKITVLANAKDAK-KQSAHGAT-
MAV_2279|M.avium_104                AVEGLILGSYRFTEFRSAKTAPKDKGLQKITVLATAKDAK-QEVAHGAA-
TH_1297|M.thermoresistible__bu      TVEGLIMGAYRFTEFRSDKTAPKDDGLRSVTVLTSEADAA-ESAVRRATQ
MSMEG_4281|M.smegmatis_MC2_155      AVEGLILGAYRFSDFRSEKTAPKGPGLTAITVLAHDTKAPTKAEAQRGVD
Mflv_2938|M.gilvum_PYR-GCK          AIEGLLLGAYRFTEFRSAKTAPTDAGIRKVTALTPDTRSATKDAAARAEA
Mvan_3575|M.vanbaalenii_PYR-1       TIEGLVLGAYRFSEFRSEKTAPKDAGVRKITVLAPDTKAATKDAAAHAEA
MAB_1948c|M.abscessus_ATCC_199      TVQGLVLGGYRFAEFRSAKTAPKDAGLQKVTLLVGDKGRAQKEAMERGAA
                                    .::**::*.***: *** ****.. *:  :* *        :     .  

Mb2236|M.bovis_AF2122/97            VATAVATARDLVNTPPSHLFPAELAKRAKTLSESVGLDVEVIDEKALKKA
Rv2213|M.tuberculosis_H37Rv         VATAVATARDLVNTPPSHLFPAEFAKRAKTLSESVGLDVEVIDEKALKKA
MMAR_3258|M.marinum_M               VATAVATARDLVNTPPSHLYPAELARRAKVLGESVGLEVQVLDEKALQKA
MUL_3573|M.ulcerans_Agy99           VATAVATARDLVNTPPSHLYPAELARRAKVLGESVGLEVQVLDEKALQKA
MLBr_00864|M.leprae_Br4923          VASAVATARDLVNTPPSHLFPAEFAKCAKTLGESAGLEVEVLDDKALQKA
MAV_2279|M.avium_104                VATAVATARDLVNTPPSHLFPDEFAKRARALGESVGLEVEVIDEKALQKG
TH_1297|M.thermoresistible__bu      VASAVAIARDFVNTPPSHLYPDEFARRAKALGESAGLTVEVLDEKALAEA
MSMEG_4281|M.smegmatis_MC2_155      IATAVATARDFVNTPPSHLFPDEFAKRAKAFGESVGLKVEVLDDKALEKA
Mflv_2938|M.gilvum_PYR-GCK          IAVAVATARDFVNTPPSHLFPAEFAERAKTLGEQAGLEVKILDEKALARD
Mvan_3575|M.vanbaalenii_PYR-1       VAAAVATARDFVNTPPSHLFPVEFAKRAKALGEAAGLQVEVLDEKALARD
MAB_1948c|M.abscessus_ATCC_199      VATAVVTARDFVNTPPSHLFPAEFAKRAKALATAEGIEVEVLDEKELAKG
                                    :* **. ***:********:* *:*. *:.:.   *: *:::*:* * . 

Mb2236|M.bovis_AF2122/97            GYGGVIGVGQGSSRPPRLVRLIHRGSRLAKNPQKAKKVALVGKGITFDTG
Rv2213|M.tuberculosis_H37Rv         GYGGVIGVGQGSSRPPRLVRLIHRGSRLAKNPQKAKKVALVGKGITFDTG
MMAR_3258|M.marinum_M               GYGGLVGVGQGSSRPPRLVRLTHRGSRLAKNPRRAKKVALVGKGVTFDTG
MUL_3573|M.ulcerans_Agy99           GYGGLVGVGQGSSRPPRLVRLTHRGSRLAKNPRRAKKVALVGKGVTFDTG
MLBr_00864|M.leprae_Br4923          GYGGVIGVGQGSSRTPRLVRLIHQGSRLAKNPKNARKVALVGKGITFDTG
MAV_2279|M.avium_104                GYGGILGVGQGSSRPPRLVRLIHRGSRLAKKSKQAKKVALVGKGVTFDTG
TH_1297|M.thermoresistible__bu      GYGGIVGVGQGSSRPPRLVRLTHRGG----DGENRKKVALVGKGITFDTG
MSMEG_4281|M.smegmatis_MC2_155      GYGGIIGVGKGSSRPPRLVRLSHLGAK-----RKGKRVALVGKGITFDTG
Mflv_2938|M.gilvum_PYR-GCK          GYGGIIGVGKGSSRPPRLVRLAHRGG-----GRKGKKVALVGKGITFDTG
Mvan_3575|M.vanbaalenii_PYR-1       GYGGIVGVGKGSSRPPRLVRLAHLGG-----GRKGKKVALVGKGITFDTG
MAB_1948c|M.abscessus_ATCC_199      GYGGIVGVGKGSSRPPRLVRLTYRGAK----GKKAKSVALVGKGITFDTG
                                    ****::***:****.****** : *.      .. : *******:*****

Mb2236|M.bovis_AF2122/97            GISIKPAASMHHMTSDMGGAAAVIATVTLAARLRLPIDVIATVPMAENMP
Rv2213|M.tuberculosis_H37Rv         GISIKPAASMHHMTSDMGGAAAVIATVTLAARLRLPIDVIATVPMAENMP
MMAR_3258|M.marinum_M               GISIKPAASMHYMTSDMGGAAAVIATVALAAQLELPIDVIATVPIAENMP
MUL_3573|M.ulcerans_Agy99           GISIKPAASMHYMTSDMGGAAAVIATVALAAQLELPINVIATVPIAENMP
MLBr_00864|M.leprae_Br4923          GISIKPAASMHHMTSDMAGAAAVIATITLAAQLKLPIDVVATVPMAENMP
MAV_2279|M.avium_104                GISIKPAASMHHMTSDMGGAAAVIATVALAARLQLPIDVIATVPMAENMP
TH_1297|M.thermoresistible__bu      GISIKPAANMHHMTSDMSGAAAVIATMVLVAQQQLPIDVIATVPMAENMP
MSMEG_4281|M.smegmatis_MC2_155      GISIKPAANMHHMTSDMGGAAAVIATVALAAVRQLPIDVIATVPMAENMP
Mflv_2938|M.gilvum_PYR-GCK          GISIKPAANMHHMTSDMGGAAAVIATVVLAARQKLPIDVVAYVPMAENMP
Mvan_3575|M.vanbaalenii_PYR-1       GISIKPAANMHHMTSDMGGAAAVIATVLLAARRRLPIDVVAYVPMAENMP
MAB_1948c|M.abscessus_ATCC_199      GISIKPAGGMENMTSDMGGAAAVIAVTLLAARQQLPIDVIATVPMAENMP
                                    *******..*. *****.*******.  *.*  .***:*:* **:*****

Mb2236|M.bovis_AF2122/97            SATAQRPGDVLTQYGGTTVEVLNTDAEGRLILADAIVRACEDKPDYLIET
Rv2213|M.tuberculosis_H37Rv         SATAQRPGDVLTQYGGTTVEVLNTDAEGRLILADAIVRACEDKPDYLIET
MMAR_3258|M.marinum_M               SATAQRPGDVLTQYGGTTVEVLNTDAEGRLILADAIVRACEDNPDYLIET
MUL_3573|M.ulcerans_Agy99           SATAQRPGDVLTQYGGTTVEVLNTDAEGRLILADAIVRACEDNPDYLIET
MLBr_00864|M.leprae_Br4923          SGTAQRPGDVLTQYGGITVEVLNTDAEGRLILADAIVRACQDNPDYLIET
MAV_2279|M.avium_104                SGTAQRPGDVLTQYGGTTVEVQNTDAEGRLILADAIVRACEDNPDYLIET
TH_1297|M.thermoresistible__bu      SATAQRPGDVLTQYGGTTVEVLNTDAEGRLILADAIVRACEDEPDYLIET
MSMEG_4281|M.smegmatis_MC2_155      SATAQRPGDVLTQYGGITVEVLNTDAEGRLILADAIVRACEDNPDYLIET
Mflv_2938|M.gilvum_PYR-GCK          SSTAQRPGDVLTQYGGITVEVLNTDAEGRLVLADAIVRACEDNPDYLIET
Mvan_3575|M.vanbaalenii_PYR-1       SATAQRPGDVLTQYGGITVEVLNTDAEGRLILADAIARACEDAPDYLIET
MAB_1948c|M.abscessus_ATCC_199      SSTAQRPGDVLTQLDGTTVEVINTDAEGRLILADAIVRACRDQPDYLIDT
                                    *.*********** .* **** ********:*****.***.* *****:*

Mb2236|M.bovis_AF2122/97            STLTGAQTVALGTRIPGVMGSDEFRDRVAAISQRVGENGWPMPLPDDLKD
Rv2213|M.tuberculosis_H37Rv         STLTGAQTVALGTRIPGVMGSDEFRDRVAAISQRVGENGWPMPLPDDLKD
MMAR_3258|M.marinum_M               STLTGAQTVALGARIPGVMGSDEFRDRVAAISQQVGENGWPMPLPDELKD
MUL_3573|M.ulcerans_Agy99           STLTGAQTVALGARIPGVMGSDEFRDRVAAISQQVGENGWPMPLPDELKD
MLBr_00864|M.leprae_Br4923          STLTGAQTVALGSRIPGVMGSDKFRDRVAKTSQQVGENGWPMPLPDELKD
MAV_2279|M.avium_104                STLTGAQTVALGARIPGVMGSDEFRDRVAAISQRVGENGWPMPLPDELKE
TH_1297|M.thermoresistible__bu      STLTGAQTIALGARTPGVMGSDEFRDRVAALSQRVGENGWAMPLPEELKE
MSMEG_4281|M.smegmatis_MC2_155      STLTGAQTVALGARTPGVMGSDEFRDRVAKLSQDVGENGWPMPLPEELRD
Mflv_2938|M.gilvum_PYR-GCK          STLTGAQTVALGSRTPGVMGSDEFRDRVAEISQEVGENAWAMPLPEELKD
Mvan_3575|M.vanbaalenii_PYR-1       STLTGAQTVALGARTPGVMGSDDFRDRVAGISQAVGENGWAMPLPEELKD
MAB_1948c|M.abscessus_ATCC_199      ATLTGAQVVALGTRTPGVMGTDEFRDRVSAISQSVGENGWAMPLPEELRD
                                    :******.:***:* *****:*.*****:  ** ****.*.****::*::

Mb2236|M.bovis_AF2122/97            DLKSTVADLANVSGQRFAGMLVAGVFLREFVAESVDWAHIDVAGPAYNTG
Rv2213|M.tuberculosis_H37Rv         DLKSTVADLANVSGQRFAGMLVAGVFLREFVAESVDWAHIDVAGPAYNTG
MMAR_3258|M.marinum_M               DLKSTVADLANVSGQRFAGMLVAGVFLREFVADAVDWAHIDVAGPAYNTG
MUL_3573|M.ulcerans_Agy99           DLKSTVADLANVSGQRFAGMLVAGVFLREFVADAVDWAHIDVAGPAYNTG
MLBr_00864|M.leprae_Br4923          DLKSTVADLANVSGQRFAGMLVAGAFLREFVADGVDWAHIDIAGPAYNTD
MAV_2279|M.avium_104                DLKSTVADLSNISGQRFAGMLVAGVFLREFVADGVGWAHIDVAGPAYNTG
TH_1297|M.thermoresistible__bu      ELKSTVADLANVGSSRYAGMLLAGAFLREFVADGVQWAHIDIAAPAYNTG
MSMEG_4281|M.smegmatis_MC2_155      DLKSTVADLANVSGSRFAGMLVAGTYLREFVAEGVQWAHIDVAAPAYNTG
Mflv_2938|M.gilvum_PYR-GCK          DLKSTVADLANVSGSRFAGMLVAGTYLREFVADGVEWAHIDIAAPAYNSG
Mvan_3575|M.vanbaalenii_PYR-1       DLKSTVADLANVSGSRFAGMLVAGTYLREFVADGVEWAHIDVAAPAYNSG
MAB_1948c|M.abscessus_ATCC_199      DLKSRVADLANVTNHRNGGMLAAGQYLREFVADGVQWAHIDVAGPAYNTG
                                    :*** ****:*: . * .*** ** :******:.* *****:*.****:.

Mb2236|M.bovis_AF2122/97            SAWGYTPKGATGVPTRTMFAVLEDIAKNG
Rv2213|M.tuberculosis_H37Rv         SAWGYTPKGATGVPTRTMFAVLEDIAKNG
MMAR_3258|M.marinum_M               SAWGYTPKGATGVPTRTMFAVLEDIAANG
MUL_3573|M.ulcerans_Agy99           SAWGYTPKGATGVPTRTMFAVLEDIAANG
MLBr_00864|M.leprae_Br4923          SPWGYTPKGATGVPTRTMFAMLEDIANHG
MAV_2279|M.avium_104                SPWGYSPKGATGVPTRTMFAVLEDIAANG
TH_1297|M.thermoresistible__bu      SPWGYTPKGGTGVPTRTLFAVLKDICRNG
MSMEG_4281|M.smegmatis_MC2_155      GPWGYTPKGGTGVPARTMFAVLEDIAANG
Mflv_2938|M.gilvum_PYR-GCK          GPWGYTPKGGTGVPTRTMFAVLEDIAANG
Mvan_3575|M.vanbaalenii_PYR-1       GPWGYTPKGGTGVPTRTMFAVLEDIAANG
MAB_1948c|M.abscessus_ATCC_199      GPWGYTPKGGTGVPVRTIFGVLEDIAANG
                                    ..***:***.****.**:*.:*:**. :*