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CQQGRPLGWDAVSDVPELIHGPLEDRHRELGASFAEFGGWLMPVSYAGTVSEHNATRTAVGLFDVSHLGK ALVRGPGAAQFVNSALTNDLGRIGPGKAQYTLCCTESGGVIDDLIAYYVSDDEIFLVPNAANTAAVVGAL QAAAPGGLSITNLHRSYAVLAVQGPCSTDVLTALGLPTEMDYMGYADASYSGVPVRVCRTGYTGEHGYEL LPPWESAGVVFDALLAAVSAAGGEPAGLGARDTLRTEMGYPLHGHELSLDISPLQARCGWAVGWRKDAFF GRAALLAEKAAGPRRLLRGLRMVGRGVLRPGLAVLVGDETVGVTTSGTFSPTLQVGIGLALIDSDAGIED GQQINVDVRGRAVECQVVCPPFVAVKTR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2211c | gcvT | - | 100% (379) | glycine cleavage system aminomethyltransferase T |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2234c | gcvT | 0.0 | 100.00% (379) | glycine cleavage system aminomethyltransferase T |
| M. gilvum PYR-GCK | Mflv_2939 | gcvT | 1e-168 | 78.92% (370) | glycine cleavage system aminomethyltransferase T |
| M. leprae Br4923 | MLBr_00865 | gcvT | 0.0 | 84.74% (367) | glycine cleavage system aminomethyltransferase T |
| M. abscessus ATCC 19977 | MAB_1949 | gcvT | 1e-159 | 75.21% (359) | glycine cleavage system aminomethyltransferase T |
| M. marinum M | MMAR_3256 | gcvT | 0.0 | 88.83% (367) | aminomethyltransferase GcvT |
| M. avium 104 | MAV_2280 | gcvT | 0.0 | 84.74% (367) | glycine cleavage system aminomethyltransferase T |
| M. smegmatis MC2 155 | MSMEG_4278 | gcvT | 1e-174 | 82.29% (367) | glycine cleavage system aminomethyltransferase T |
| M. thermoresistible (build 8) | TH_1298 | gcvT | 1e-163 | 75.75% (367) | Probable aminomethyltransferase GcvT (Glycine cleavage |
| M. ulcerans Agy99 | MUL_3571 | gcvT | 0.0 | 88.01% (367) | glycine cleavage system aminomethyltransferase T |
| M. vanbaalenii PYR-1 | Mvan_3574 | gcvT | 1e-174 | 80.81% (370) | glycine cleavage system aminomethyltransferase T |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2939|M.gilvum_PYR-GCK ----------MWIVVSDNLLAGPLENRHRELGATFAEFGGWSMPVSYAGT
Mvan_3574|M.vanbaalenii_PYR-1 ----------MWFAVTDNLLAGPLENRHRELGASFAEFGGWLMPVSYAGT
MSMEG_4278|M.smegmatis_MC2_155 --------------MSDELLQGPLEDRHRELGAAFAEFGGWLMPVSYAGT
Rv2211c|M.tuberculosis_H37Rv MCQQGRPLGWDAVSDVPELIHGPLEDRHRELGASFAEFGGWLMPVSYAGT
Mb2234c|M.bovis_AF2122/97 MCQQGRPLGWDAVSDVPELIHGPLEDRHRELGASFAEFGGWLMPVSYAGT
MMAR_3256|M.marinum_M ------------MSDAPELMQGPLEDRHRALGASFAEFGGWLMPVSYAGT
MUL_3571|M.ulcerans_Agy99 ------------MSDAPELMQGPLEDRHRALGASFAEFGGWLMPVSYTGT
MLBr_00865|M.leprae_Br4923 ------------MTDAPELLKGPLEDRHRELGANFAEFGGWLMPVSYAGT
MAV_2280|M.avium_104 ------------MSNEADLLHGPLEDRHRDLGASFAEFGGWLMPVSYAGT
TH_1298|M.thermoresistible__bu ------------VTGVSDIQHGPLEERHRQLGANFAEFGGWLMPVSYAGT
MAB_1949|M.abscessus_ATCC_1997 ---------------MTDLLLGPLHDRHAAQGATFAEFGGWNMPVSYAGT
:: ***.:** ** ******* *****:**
Mflv_2939|M.gilvum_PYR-GCK VAEHTATRTTVGLFDVSHLGKALVTGPGAAEFVNSAFTNDLRRIGPGKAQ
Mvan_3574|M.vanbaalenii_PYR-1 VAEHTATRTTVGLFDVSHLGKALVKGPGAAEFVNSAFTNDLRRIGPGQAQ
MSMEG_4278|M.smegmatis_MC2_155 VAEHNATRSTVGLFDVSHLGKALVKGPGAAAYVNSALTNDLGKIGPGKAQ
Rv2211c|M.tuberculosis_H37Rv VSEHNATRTAVGLFDVSHLGKALVRGPGAAQFVNSALTNDLGRIGPGKAQ
Mb2234c|M.bovis_AF2122/97 VSEHNATRTAVGLFDVSHLGKALVRGPGAAQFVNSALTNDLGRIGPGKAQ
MMAR_3256|M.marinum_M VSEHNATRNAAGLFDVSHLGKALVRGPGAAEFVNSALTNDLRRIGPGKAQ
MUL_3571|M.ulcerans_Agy99 VSEHNATRNAAGLFDVSHLGKALVRGPGAAEFVNSALTNDLRRIGPGKAQ
MLBr_00865|M.leprae_Br4923 VSEHSATRNAVGLFDVSHLGKALVRGPGAAQFVNSVLTNDLGRIRPGKAQ
MAV_2280|M.avium_104 VSEHNATRNAVGLFDVSHLGKALVRGTGAARFVNSALTNDLNRIGPGKAQ
TH_1298|M.thermoresistible__bu VSEHTATRTTVGLFDVSHLGKARVRGPGAADFVNSAFTNDLRRIGPGSAQ
MAB_1949|M.abscessus_ATCC_1997 VGEHTATRAAVGLFDVSHLGKALVRGPGAAAFVNACFTNDLNKVGPGKAQ
*.**.*** :.*********** * *.*** :**: :**** :: **.**
Mflv_2939|M.gilvum_PYR-GCK YTLCCTEDGGVIDDLIAYYVSDDEIFLVPNAANTAAVVAALQDRAPDGIT
Mvan_3574|M.vanbaalenii_PYR-1 YTLCCTEDGGVIDDLIAYYVSDDEIFLVPNAANTAAVVAALQQRAPGGLT
MSMEG_4278|M.smegmatis_MC2_155 YTLCCTESGGVIDDLIAYYVSDDEIFLVPNAANTATVVEELQRHAPDGLT
Rv2211c|M.tuberculosis_H37Rv YTLCCTESGGVIDDLIAYYVSDDEIFLVPNAANTAAVVGALQAAAPGGLS
Mb2234c|M.bovis_AF2122/97 YTLCCTESGGVIDDLIAYYVSDDEIFLVPNAANTAAVVGALQAAAPGGLS
MMAR_3256|M.marinum_M YTLCCNESGGVIDDLIAYYVADDEIFLVPNAANTAAVVAALQAAAPSGLT
MUL_3571|M.ulcerans_Agy99 YTLCCNESGGVIDDLIAYYVADDEIFLVPNAANTAAVVAALQAAAPSGLT
MLBr_00865|M.leprae_Br4923 YTLCCSESGGVIDDLIAYYVDDDEIFLVSNAANTAAVVDALQAVVPAGLT
MAV_2280|M.avium_104 YTLCCNESGGVIDDLIAYYVDDDEIFLVPNAANTAAVVEALQGAAPAGVT
TH_1298|M.thermoresistible__bu YTLCCTESGGVVDDLIAYYISDDEIFLVPNAANNATVVDLLRRHAPAGVE
MAB_1949|M.abscessus_ATCC_1997 YTLCCTETGGVIDDLIAYYVSDDEIFLVPNAANTSAVVAALQEQAPEGIA
*****.* ***:*******: *******.****.::** *: .* *:
Mflv_2939|M.gilvum_PYR-GCK ITDEHRSRAVLAVQGPRSADVVGGLGLPTDMDYMGFADGEVGGVETRVCR
Mvan_3574|M.vanbaalenii_PYR-1 ITDEHRSRAVLAVQGPVSADVVGGLGLPTDMDYMGYADAEFRGVEVRVCR
MSMEG_4278|M.smegmatis_MC2_155 ITNEHRSYAVLAVQGPKSAEVLDKLGLPTDMDYMGYADAEFDGVFVRVCR
Rv2211c|M.tuberculosis_H37Rv ITNLHRSYAVLAVQGPCSTDVLTALGLPTEMDYMGYADASYSGVPVRVCR
Mb2234c|M.bovis_AF2122/97 ITNLHRSYAVLAVQGPCSTDVLTALGLPTEMDYMGYADASYSGVPVRVCR
MMAR_3256|M.marinum_M ITDLHRSYAVLAVQGPRSTEVLAALGLPTEMDYMGYADSSYNGVSVRVCR
MUL_3571|M.ulcerans_Agy99 ITDLHRSYAVLAVQGPRSTEVLAALGLPTEMDYMGYADSSYNGVSVRVCR
MLBr_00865|M.leprae_Br4923 IINQHRSHAVLAVQGPRSTDVLGELGLPTGIDYMGYVDASYAGVPVRVCR
MAV_2280|M.avium_104 VSNLHRSYAVLAVQGPRSADVLAELGLPSDMDYMAYADTSFRQVPVRVCR
TH_1298|M.thermoresistible__bu VIDEHRAHAVFAVQGPRSADVLSGLGLPVDMDYMAFTDATLNGVEVRVCR
MAB_1949|M.abscessus_ATCC_1997 VTNQHRDYAVLAVQGPRSADVLQRLGLPTDMEYMAYADATLAGLPVRVCR
: : ** **:***** *::*: **** ::**.:.* : .****
Mflv_2939|M.gilvum_PYR-GCK TGYTGEHGYELLPAWDQAEVVFDALVESVRAAGGEPAGLGARDTLRTEMG
Mvan_3574|M.vanbaalenii_PYR-1 TGYTGEHGYELLPPWDQAAVVFDALVEAVQSAGGEPAGLGARDTLRTEMG
MSMEG_4278|M.smegmatis_MC2_155 TGYTGEHGYELLPAWDRAGVVFDALVAAVRAAGGEPAGLGARDTLRTEMG
Rv2211c|M.tuberculosis_H37Rv TGYTGEHGYELLPPWESAGVVFDALLAAVSAAGGEPAGLGARDTLRTEMG
Mb2234c|M.bovis_AF2122/97 TGYTGEHGYELLPPWESAGVVFDALLAAVSAAGGEPAGLGARDTLRTEMG
MMAR_3256|M.marinum_M TGYTGEHGYELLPPWESAGVVFDALAAAVAEVGGEPAGLGARDTLRTEMG
MUL_3571|M.ulcerans_Agy99 TGYTGEHGYELLPPWESAGVVFDALAAAVAEVGGSPAGLGARDTLRTEMG
MLBr_00865|M.leprae_Br4923 TGYTGEQGYELLPPWESADVVFDALVAAVVDARGEPAGLGARDTLRTEMG
MAV_2280|M.avium_104 TGYTGEHGYELLPPWESAGVVFDALAAAVSQAGGQPAGLGARDTLRTEMG
TH_1298|M.thermoresistible__bu TGYTGEHGYEVLPPWESALPVFDALVDAVQAAGGQLAGLGARDTLRTEMG
MAB_1949|M.abscessus_ATCC_1997 TGYTGEHGYELLPSWDDAGAVFDALLPVITEAGGQLAGLGARDTLRTEMG
******:***:**.*: * ***** : . *. **************
Mflv_2939|M.gilvum_PYR-GCK YPLHGHELSLDISPLQARCGWAIGWKKDAFWGRDALLAEKEAGPRRTLRG
Mvan_3574|M.vanbaalenii_PYR-1 YPLHGHELSLDISPLQARCGWAIGWKKDAFWGRDALLAEKAAGPRRTLRG
MSMEG_4278|M.smegmatis_MC2_155 YPLHGHELSLDISPLQARCGWAVGWKKDAFWGRDALLAEKADGPKRVLRG
Rv2211c|M.tuberculosis_H37Rv YPLHGHELSLDISPLQARCGWAVGWRKDAFFGRAALLAEKAAGPRRLLRG
Mb2234c|M.bovis_AF2122/97 YPLHGHELSLDISPLQARCGWAVGWRKDAFFGRAALLAEKAAGPRRLLRG
MMAR_3256|M.marinum_M YPLHGHELSLDISPLQARCGWAIGWKKDAFFGREALLAEKAAGPRRLLRG
MUL_3571|M.ulcerans_Agy99 YPLHGHELSLDISPLQARCGWAIGWKKDAFFGREALLAEKAAGPRRLPRG
MLBr_00865|M.leprae_Br4923 YPLYGHELSLDISPLQARCGWAIGWKKDAFLGRDALLAEKAAGPRRLLRG
MAV_2280|M.avium_104 YPLHGHELSPDISPLQARCGWAIGWKKEAFFGRDALLAEKEAGPRRLLRG
TH_1298|M.thermoresistible__bu YPLHGHELSPDISPLEARCGWAVGWKKERFWGRDALLAEKQAGPRRLLRG
MAB_1949|M.abscessus_ATCC_1997 YPLHGHELSLDISPVQARAGWAVGWKKDAFWGREALTQEKTDGPRRTLRG
***:***** ****::**.***:**:*: * ** ** ** **:* **
Mflv_2939|M.gilvum_PYR-GCK LRAVGRGVLRADLSVLTDDTPVGFTTSGTFSPTLKVGIALALIDTAAGIA
Mvan_3574|M.vanbaalenii_PYR-1 LRAVGRGVLRQDLTVLDGENRVGVTTSGTFSPTLKVGIALALIDTEADIT
MSMEG_4278|M.smegmatis_MC2_155 LKALGRGVLRADLAVLDGDTRVGVTTSGTFSPTLKVGIALALIDTEYDIA
Rv2211c|M.tuberculosis_H37Rv LRMVGRGVLRPGLAVLVGDETVGVTTSGTFSPTLQVGIGLALIDSDAGIE
Mb2234c|M.bovis_AF2122/97 LRMVGRGVLRPGLAVLVGDETVGVTTSGTFSPTLQVGIGLALIDSDAGIE
MMAR_3256|M.marinum_M LRMVGRGVLRPGLTVLNGSTPVGVTTSGTFSPTLQIGIALALIDTDAGVE
MUL_3571|M.ulcerans_Agy99 LRMVGRGVLRPGLTVLNGSTPVGVTTSGTFSPTLQIGIALALIDTDAGVE
MLBr_00865|M.leprae_Br4923 LRMAGRGVLRPGLTVCAGDIPIGVTTSGTFSPTLQVGVALALIDSEAAVQ
MAV_2280|M.avium_104 LRMVGRGVLRAGLTVLVGDTPVGVTTSGTFSPTLQAGIALALIDTDADVR
TH_1298|M.thermoresistible__bu LRAVDRGVLRAGLSVYDGDTVVGTTTSGTFSPTLKVGIALALIDTEHGIP
MAB_1949|M.abscessus_ATCC_1997 LRATGRGVLRPDLTVLSDGQSIGVTTSGTFSPTLKTGIALALLDTAAQIP
*: .***** .*:* . :* **********: *:.***:*: :
Mflv_2939|M.gilvum_PYR-GCK DGDHVTVDVRGRRVECEVVKPPFVDTRTR
Mvan_3574|M.vanbaalenii_PYR-1 DGAHVDVDVRGRRIECEVVKPPFVDTRTR
MSMEG_4278|M.smegmatis_MC2_155 DGTTVTVDVRGRAVECEVVKPPFVTPSTR
Rv2211c|M.tuberculosis_H37Rv DGQQINVDVRGRAVECQVVCPPFVAVKTR
Mb2234c|M.bovis_AF2122/97 DGQQINVDVRGRAVECQVVCPPFVAVKTR
MMAR_3256|M.marinum_M DGQQITVDVRGRAVECEVVRPPFVEAKTR
MUL_3571|M.ulcerans_Agy99 DGQQITVDVRGRAVECEVVRPPFVEAKTR
MLBr_00865|M.leprae_Br4923 DGQQIIVDVRGRAVECEVVRPPFIEVKTR
MAV_2280|M.avium_104 DGQKVTVDVRGRAATCEVVRPPFVAVKTR
TH_1298|M.thermoresistible__bu DGARVSVDVRGRRIGCEVVKPPFVEVKTR
MAB_1949|M.abscessus_ATCC_1997 DGASVVVDVRGREIECEVVKPPFVDVNVG
** : ****** *:** ***: .