For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. tuberculosis H37Rv Rv2194 (qcrC)

annotation: Probable Ubiquinol-cytochrome C reductase QcrC(cytochrome C subunit)
coordinates: 2457553 - 2458395
length: 280

LTKLGFTRSGGSKSGRTRRRLRRRLSGGVLLLIALTIAGGLAAVLTPTPQVAVADESSSALLRTGKQLFD
TSCVSCHGANLQGVPDHGPSLIGVGEAAVYFQVSTGRMPAMRGEAQAPRKDPIFDEAQIDAIGAYVQANG
GGPTVVRNPDGSIATQSLRGNDLGRGGDLFRLNCASCHNFTGKGGALSSGKYAPDLAPANEQQILTAMLT
GPQNMPKFSNRQLSFEAKKDIIAYVKVATEARQPGGYLLGGFGPAPEGMAMWIIGMVAAIGLALWIGARS
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv2194qcrC-100% (280)Probable Ubiquinol-cytochrome C reductase QcrC(cytochrome C subunit)

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2217qcrC1e-160100.00% (280) ubiquinol-cytochrome C reductase QcrC (cytochrome C subunit)
M. gilvum PYR-GCKMflv_2955-1e-11574.45% (274) cytochrome c, class I
M. leprae Br4923MLBr_00881qcrC1e-14184.78% (289) putative cytochrome C reductase cytochrome C component
M. abscessus ATCC 19977MAB_1968c-1e-12177.36% (265) ubiquinol-cytochrome c reductase cytochrome c subunit
M. marinum MMMAR_3238qcrC1e-14183.06% (301) ubiquinol-cytochrome C reductase QcrC
M. avium 104MAV_2298-1e-13787.36% (269) cytochrome c family protein
M. smegmatis MC2 155MSMEG_4261-1e-12078.28% (267) ubiquinol-cytochrome c reductase cytochrome c subunit
M. thermoresistible (build 8)TH_1042qcrC6e-9875.00% (228) Probable Ubiquinol-cytochrome C reductase QcrC(cytochrome C
M. ulcerans Agy99MUL_3551qcrC1e-14082.72% (301) ubiquinol-cytochrome C reductase QcrC
M. vanbaalenii PYR-1Mvan_3558-1e-11473.70% (270) cytochrome c, class I

CLUSTAL 2.0.9 multiple sequence alignment


Rv2194|M.tuberculosis_H37Rv         MTKLGFTRSGG---------------------SKSGRTRRRLRRRLSGGV
Mb2217|M.bovis_AF2122/97            MTKLGFTRSGG---------------------SKSGRTRRRLRRRLSGGV
MLBr_00881|M.leprae_Br4923          MKKLGFTRSSRR------------CSQPQEREQESERSRRRLRRRLSEGL
MMAR_3238|M.marinum_M               MKKLGFTRSGGSEPVARRLVGALRGPRSHRSEQRTSRARRRLHRRLSGGL
MUL_3551|M.ulcerans_Agy99           MKKLGFTRSGGSEPVARRLVGALRGPRSHRSEQRTSRARRRLHRRLSGGL
MAV_2298|M.avium_104                MKKLRST--------------------------RTDRSRRRLRRRLSGGL
MSMEG_4261|M.smegmatis_MC2_155      ---------------------------------MTSKSRRRLRRRLSAGL
Mflv_2955|M.gilvum_PYR-GCK          -----------------------MTDKSRRAGRPATVRRRRLRRRATAAL
Mvan_3558|M.vanbaalenii_PYR-1       ----------------------------MRRGSMTSKSRRRLRRRVTAAL
MAB_1968c|M.abscessus_ATCC_199      MPDGPKTQPSPVKG------AQQVSVEPVKDTAAKNRARRKFRRRVSAGL
TH_1042|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Rv2194|M.tuberculosis_H37Rv         LLLIALTIAGGLAAVLTPTPQVAVADESSSALLRTGKQLFDTSCVSCHGA
Mb2217|M.bovis_AF2122/97            LLLIALTIAGGLAAVLTPTPQVAVADESSSALLRTGKQLFDTSCVSCHGA
MLBr_00881|M.leprae_Br4923          LLLVALTVSGGLAAVLTPTPQVAVADEDSSALLRTGKQLFDTSCVSCHGA
MMAR_3238|M.marinum_M               LLLIALTIAGGVAAVLTPAPQVAVADESSAALLRTGKQLFDTSCVSCHGA
MUL_3551|M.ulcerans_Agy99           LLLIALTIAGGVAAVLTPAPQVAVADESSAALLRTGKQLFDTSCVSCHGA
MAV_2298|M.avium_104                LLLIALTIAGGLAAILTPRPQVAVADESNSALLRTGKQLFDTSCVSCHGA
MSMEG_4261|M.smegmatis_MC2_155      LLLIGLAVAGGVAATLTPQPQVAVADESQSALLRTGKQLFETSCVSCHGA
Mflv_2955|M.gilvum_PYR-GCK          LLLSGLVMAGGLAATLTPQPQVAVADESASAMLRTGQQLYDTSCVSCHGV
Mvan_3558|M.vanbaalenii_PYR-1       LLLSGLVMAGGLAATLTPSPQVAVADESASALLRTGQQLYETSCVSCHGV
MAB_1968c|M.abscessus_ATCC_199      LLLIALVVAGGLASTFTPTPQVAVADEDKSALLRTGKQLYETSCITCHGA
TH_1042|M.thermoresistible__bu      -----------------------VADEAQSALLRTGKELYETSCISCHGA
                                                           ****  :*:****::*::***::***.

Rv2194|M.tuberculosis_H37Rv         NLQGVPDHGPSLIGVGEAAVYFQVSTGRMPAMRGEAQAPRKDPIFDEAQI
Mb2217|M.bovis_AF2122/97            NLQGVPDHGPSLIGVGEAAVYFQVSTGRMPAMRGEAQAPRKDPIFDEAQI
MLBr_00881|M.leprae_Br4923          NLQGVPDHGPSLIGVGEAAVYFQVSTGRMPAMRGEAQVARKDPIFNESQI
MMAR_3238|M.marinum_M               NLQGVPDHGPSLIGVGEAAVYFQVSTGRMPAMRGEAQAQRKEPIFDEAQT
MUL_3551|M.ulcerans_Agy99           NLQGVPDHGPSLIGVGEAAVYFQVSTGRMPAMRGEAQAQRKEPIFDEAQT
MAV_2298|M.avium_104                NLQGVPDRGPSLIGVGEEAVYFQVSTGRMPAMTGEAQAPRKEPVFDEAQT
MSMEG_4261|M.smegmatis_MC2_155      NLQGVPDRGPSLIGTGEAAVYFQVSTGRMPAMRGEAQAPSKPPHFDESQI
Mflv_2955|M.gilvum_PYR-GCK          NLQGVADRGPSLIGVGEAAVYFQVSTGRMPAMRGEAQAPQKPRQFDEAQT
Mvan_3558|M.vanbaalenii_PYR-1       NLQGVADRGPSLIGVGEAAVYFQVSSGRMPAMRNEAQIERKDPVFDEAQT
MAB_1968c|M.abscessus_ATCC_199      NLQGVPDRGPSLIGVGEAAVYFQVSTGRMPAMRNEAQAQRKDPIFDEEQT
TH_1042|M.thermoresistible__bu      NLQGVYDRGPSLIGVGEASVYFQVSTGRMPAKTGQAQAPEKTPDFDQAQM
                                    ***** *:******.** :******:*****  .:**   *   *:: * 

Rv2194|M.tuberculosis_H37Rv         DAIGAYVQANGGGPTVVRNPDGSIATQSLRGNDLGRGGDLFRLNCASCHN
Mb2217|M.bovis_AF2122/97            DAIGAYVQANGGGPTVVRNPDGSIATQSLRGNDLGRGGDLFRLNCASCHN
MLBr_00881|M.leprae_Br4923          DAIGAYIQANGGGPTVARNPDGSVAMQSLRGTDLGRGGDLFRLNCASCHN
MMAR_3238|M.marinum_M               DALGAFVQANGGGPTVVRNPDGSLAMKSLRGDDLGRGGDLFRLNCTSCHN
MUL_3551|M.ulcerans_Agy99           DALGAFVQANGGGPTVVRNPDGSLAMKSLRGDDLGRGGDLFRLNCTSCHN
MAV_2298|M.avium_104                DALGAYVQANGGGPTTVRNPDGSLAMRSLRGEDLGRGGDLFRLNCSSCHN
MSMEG_4261|M.smegmatis_MC2_155      DALGAYVQANGGGPTVPRDDHGAVAQESLIGGDVARGGDLFRLNCASCHN
Mflv_2955|M.gilvum_PYR-GCK          DALGAYIQANGGGPVVPRDENGEIASQSLIGNDVARGGDLFRLNCASCHN
Mvan_3558|M.vanbaalenii_PYR-1       DALGAYIQANGGGPVVPRDENGHVAEQSLIGNDVARGGDLFRLNCASCHN
MAB_1968c|M.abscessus_ATCC_199      DALGAYIQANGGGPQVIRDRDGAVAQESLRGNNIARGGDLFRLNCASCHN
TH_1042|M.thermoresistible__bu      DALGAYIQANGGGPTVVRDANGEIAQQSLIGDNVARGGDLFRMNCASCHN
                                    **:**::******* . *: .* :* .** * ::.*******:**:****

Rv2194|M.tuberculosis_H37Rv         FTGKGGALSSGKYAPDLAPANEQQILTAMLTGPQNMPKFSNRQLSFEAKK
Mb2217|M.bovis_AF2122/97            FTGKGGALSSGKYAPDLAPANEQQILTAMLTGPQNMPKFSNRQLSFEAKK
MLBr_00881|M.leprae_Br4923          FTGKGGALSSGKYAPDLGPANEQQILTAMLTGPQNMPKFADRQLSFEAKK
MMAR_3238|M.marinum_M               FTGKGGALSSGKFAPDLGPANEQQILTAMLTGPQNMPKFSDRQLSFDAKK
MUL_3551|M.ulcerans_Agy99           FTGKGGALSSGKFAPDLGPANEQQILTAMLTGPQNMPKFSDRQLSFDAKK
MAV_2298|M.avium_104                FTGKGGALSSGKYAPDLEPANEQQILAAMRTGPQNMPKFSDRQLSFEAKK
MSMEG_4261|M.smegmatis_MC2_155      FTGKGGALSSGKYAPDLGDANPAQIYTAMLTGPQNMPKFSDRQLTPDEKR
Mflv_2955|M.gilvum_PYR-GCK          FTGKGGALSSGKYAPDLGTANEAQIYTAMLTGPQNMPKFSDRQLSPEEKR
Mvan_3558|M.vanbaalenii_PYR-1       FTGKGGALSSGKYAPDLGVATPAQIYTAMVTGPQNMPKFSERQLSPEEKR
MAB_1968c|M.abscessus_ATCC_199      FTGRGGALSSGKFAPELDPATEQQIYTAMLTGPQNMPKFSDRQLTVDEKK
TH_1042|M.thermoresistible__bu      FTGRGGALSSGKYAPDLDNLEPAQIYTAMLTGPENMPKFSDRQLSPEDKA
                                    ***:********:**:*      ** :** ***:*****::***: : * 

Rv2194|M.tuberculosis_H37Rv         DIIAYVKVATEARQPGGYLLGGFGPAPEGMAMWIIGMVAAIGLALWIGAR
Mb2217|M.bovis_AF2122/97            DIIAYVKVATEARQPGGYLLGGFGPAPEGMAMWIIGMVAAIGLALWIGAR
MLBr_00881|M.leprae_Br4923          DIIGYVRTVIEERQPGGYSLGGFGPAPEGMAIWIIGMVTAIGLALWIGAR
MMAR_3238|M.marinum_M               DIIAYVRNAAEERQPGGYGLGGFGPAPEGMAIWIIGMVAAIGLALWIGAR
MUL_3551|M.ulcerans_Agy99           DIIAYVRNAAEERQPGGYGLGGFGPAPEGMAIWIIGMVAATGLALWIGAR
MAV_2298|M.avium_104                DIIGYIKAVTEERQPGGYGLGGFGPAPEGMAAWIIGMVAAIGLALWIGAR
MSMEG_4261|M.smegmatis_MC2_155      DIVAYVRESAETPSYGGYGLGGFGPAPEGMAMWIIGMVAAIGVAMWIGSR
Mflv_2955|M.gilvum_PYR-GCK          DIVAYVREAAETPTPGGLGLGGFGPTSEGMVAWIVGMVAIIAAALWIGAR
Mvan_3558|M.vanbaalenii_PYR-1       DIVAYVREAAETPTPGGLGLGGFGPTSEGMVAWIVGMVAIIAAALWIGAR
MAB_1968c|M.abscessus_ATCC_199      DIIAYVRASSETPDPGGYGLGGFGPTSEGMAMWIIGIVAAIAAALWIGAR
TH_1042|M.thermoresistible__bu      DIIAYVQQATKAGNPGGYGLGGFGPVGEGMAIWIIGTVAVIAAALWIGAR
                                    **:.*::   :    **  ******. ***. **:* *:  . *:***:*

Rv2194|M.tuberculosis_H37Rv         S
Mb2217|M.bovis_AF2122/97            S
MLBr_00881|M.leprae_Br4923          A
MMAR_3238|M.marinum_M               S
MUL_3551|M.ulcerans_Agy99           S
MAV_2298|M.avium_104                A
MSMEG_4261|M.smegmatis_MC2_155      A
Mflv_2955|M.gilvum_PYR-GCK          A
Mvan_3558|M.vanbaalenii_PYR-1       A
MAB_1968c|M.abscessus_ATCC_199      A
TH_1042|M.thermoresistible__bu      A
                                    :