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RDGPAAPAQVVAPADGFVALRVADDRTVRLLSLGGAATDRLLSRIAAGIDAAVDEVVAFWGTDWSHDIFV VAAGSDEQFHAAAGGGLASQWADIAAITVVDRVDPARRTVVGQRIVFAPGAAHMSPAALRIVLGHELFHY AARADTALDAPRWLAEGVADFVARPKTPPPADAVSVALSLPSDTDLDTPGPQRSLAYDRAWWFARFVAAA YGTAKLRELYLATCGVGHFDLATAAHDVLGIDAAGLLARWQRWLMG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2189c | - | - | 100% (257) | hypothetical protein Rv2189c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2212c | - | 1e-148 | 100.00% (257) | hypothetical protein Mb2212c |
| M. gilvum PYR-GCK | Mflv_2960 | - | 3e-50 | 48.00% (225) | hypothetical protein Mflv_2960 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1975 | - | 3e-35 | 39.00% (241) | hypothetical protein MAB_1975 |
| M. marinum M | MMAR_3233 | - | 1e-92 | 68.24% (255) | hypothetical protein MMAR_3233 |
| M. avium 104 | MAV_2305 | - | 7e-99 | 68.99% (258) | hypothetical protein MAV_2305 |
| M. smegmatis MC2 155 | MSMEG_4255 | - | 2e-67 | 54.55% (253) | hypothetical protein MSMEG_4255 |
| M. thermoresistible (build 8) | TH_1112 | - | 1e-62 | 57.33% (225) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_3551 | - | 1e-57 | 51.42% (247) | hypothetical protein Mvan_3551 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2960|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3551|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv2189c|M.tuberculosis_H37Rv --------------------------------------------------
Mb2212c|M.bovis_AF2122/97 --------------------------------------------------
MAV_2305|M.avium_104 --------------------------------------------------
MMAR_3233|M.marinum_M --------------------------------------------------
MSMEG_4255|M.smegmatis_MC2_155 --------------------------------------------------
TH_1112|M.thermoresistible__bu --------------------------------------------------
MAB_1975|M.abscessus_ATCC_1997 MVFVTLCGGCATRPAAPATRAGDARTSIQALLGSYATALRSNDVAALRAV
Mflv_2960|M.gilvum_PYR-GCK ------------------------MRRSTTSVATSPSRLPRSVDRRRLGA
Mvan_3551|M.vanbaalenii_PYR-1 ------------------------MRRSTTSVGTEQS---GAVARRRVGA
Rv2189c|M.tuberculosis_H37Rv --------------------------------------------------
Mb2212c|M.bovis_AF2122/97 --------------------------------------------------
MAV_2305|M.avium_104 --------------------------------------------------
MMAR_3233|M.marinum_M -----------------------------------------MLRHRSRWF
MSMEG_4255|M.smegmatis_MC2_155 --------------------------------------------------
TH_1112|M.thermoresistible__bu --------------------------------------------------
MAB_1975|M.abscessus_ATCC_1997 LVPDNPTFVAAQLRLQANLIHLKTDTFEYRTATDVPADPIATHQQWTLDA
Mflv_2960|M.gilvum_PYR-GCK VFGAELICAVLLIAGPQVSAPVPAVAAPVPATHSPQPAPTGPSTRTVATP
Mvan_3551|M.vanbaalenii_PYR-1 VLGAELVCALVLVGVPRIAPAATGPAAPMSYTQSASPVP-----HTVLTA
Rv2189c|M.tuberculosis_H37Rv ----------------------MRDGPAAPAQVVAPADG-FVALR---VA
Mb2212c|M.bovis_AF2122/97 ----------------------MRDGPAAPAQVVAPADG-FVALR---VA
MAV_2305|M.avium_104 ------MFVVELVVAAAVPFDAERDGRTRPAQLVSPVRSQFSASSRSLVV
MMAR_3233|M.marinum_M SIALACIFVIELVTAAAV----TRHPDSAPQRSLASAED---PGPPTVVI
MSMEG_4255|M.smegmatis_MC2_155 MLLVELGLAVALLGTASNPPSAGQQPHPPVSATSAPADA--APVQTFTLP
TH_1112|M.thermoresistible__bu --------------------------------------------------
MAB_1975|M.abscessus_ATCC_1997 ELFYAVSGVDTVGVQRPVTIGVRRDNDAWRLSDVSAIAVPWQFGPVIETR
Mflv_2960|M.gilvum_PYR-GCK DGRTAQLADLGAPGGGALLDRIAAELPSATAAVTAFWGPQWPRDIPIVVA
Mvan_3551|M.vanbaalenii_PYR-1 DGRTAQIIDLGGEGG-AALDRIAAELPAATEAVTAFWGPQWRRDITIVLA
Rv2189c|M.tuberculosis_H37Rv DDRTVRLLSLGGAATDRLLSRIAAGIDAAVDEVVAFWGTDWSHDIFVVAA
Mb2212c|M.bovis_AF2122/97 DDRTVRLLSLGGAATDRLLSRIAAGIDAAVDEVVAFWGTDWSHDIFVVAA
MAV_2305|M.avium_104 GDRTVRLLGLGGPASDRLLARVAAGMGAAITAVEAFWGADWSREISVVAA
MMAR_3233|M.marinum_M GDRTVRLINLGGANSDLLLSRVGADIRGAVNAVVAFWGTDWAREISVVAA
MSMEG_4255|M.smegmatis_MC2_155 DGRTARLLTLGGPQTDVLLDRIRDELLGAADAVTAFWGPDWPREIDIAVA
TH_1112|M.thermoresistible__bu -------VDLGGPHTAGLLNRIAAELDAAAAAVTAFWGDDWSREIVIAAA
MAB_1975|M.abscessus_ATCC_1997 KNVGDKKVVVLGHPGAQLAPRIADEVGGAMRSLSEFWGPQGYPGVLFVAA
: . *: : .* : *** : : .. *
Mflv_2960|M.gilvum_PYR-GCK GTTGQFATLGGGG-----DGIAATTTAQ------------RITFAPGATA
Mvan_3551|M.vanbaalenii_PYR-1 GSAEQFATLAGGG-----ADVAATTTPE------------RIMFSPAAAG
Rv2189c|M.tuberculosis_H37Rv GSDEQFHAAAGGGLASQWADIAAITVVDRVDPARRTVVGQRIVFAPGAAH
Mb2212c|M.bovis_AF2122/97 GSDEQFHAAAGGGLASQWADIAAITVVDRVDPARRTVVGQRIVFAPGAAH
MAV_2305|M.avium_104 GTDEEFRAAAGGGPATQWADIAAVTVSDRVDPVRRIASGQRIVFAPGAAN
MMAR_3233|M.marinum_M GSDEQFRTAAGGGTASQWADIAAVTVAERFDPGSRAVAGQRIVFAPGAVK
MSMEG_4255|M.smegmatis_MC2_155 GTPEQFRVLGGVG-----ADIAAITTAD------------RIVFAPGAAT
TH_1112|M.thermoresistible__bu ATDEQFTALAGGG-----PDIAAAAVDG------------RIVFAPGAAG
MAB_1975|M.abscessus_ATCC_1997 GTEAEFAALVGGEHT---EGIAAAAVADRVDGG--IAVGQRVVVAPGAAA
.: :* . * .:** :. *: .:*.*.
Mflv_2960|M.gilvum_PYR-GCK MDDADLRTVVRHELFHYAARADTAADAPVWFTEGVADYVARPPAATP---
Mvan_3551|M.vanbaalenii_PYR-1 MNTADLRTVLRHELFHYAARADTAADAPVWLTEGVADFVGRPPAAEP---
Rv2189c|M.tuberculosis_H37Rv MSPAALRIVLGHELFHYAARADTALDAPRWLAEGVADFVARPKTPPP---
Mb2212c|M.bovis_AF2122/97 MSPAALRIVLGHELFHYAARADTALDAPRWLAEGVADFVARPKTPPP---
MAV_2305|M.avium_104 MSPASLRIVVAHELFHYASRADTVADAPRWLTEGVADFVGRPPAPVP---
MMAR_3233|M.marinum_M MSATALRIVLTHELFHYAARVDTALDAPRWLTEGVADFVARPTTSRP---
MSMEG_4255|M.smegmatis_MC2_155 MSPAALRIVLRHELFHYAARSVTAYDAPRWLTEGVADYVARPDAPRPG--
TH_1112|M.thermoresistible__bu MSADALRMVLRHELFHHAALPRTAGDAPRWLTEGVADFVARPGGRPEL--
MAB_1975|M.abscessus_ATCC_1997 LPADQFRVVLRHELFHAAARTVTGDHAPLWLVEGVADYNGRRGSGTPFRN
: :* *: ***** *: * .** *:.*****: .*
Mflv_2960|M.gilvum_PYR-GCK -----------PAAPRGFPSDAEMAAPGPARDEAYDRAWEFASYVAGVYG
Mvan_3551|M.vanbaalenii_PYR-1 -----------PGAPASLPTDAELATPGPGRSDAYDRAWQFASHIAATYG
Rv2189c|M.tuberculosis_H37Rv --------ADAVSVALSLPSDTDLDTPGPQRSLAYDRAWWFARFVAAAYG
Mb2212c|M.bovis_AF2122/97 --------ADAVSVALSLPSDTDLDTPGPQRSLAYDRAWWFARFVAAAYG
MAV_2305|M.avium_104 --------ADAL-LPLTLPSDTDLDVPGPQRSSAYDRAWWFARFVADSYG
MMAR_3233|M.marinum_M --------AEAP--PAALPSDDDLDIPGPARSRAYDRAWWFTRFVADTYG
MSMEG_4255|M.smegmatis_MC2_155 --------PQAAQMLARLPTDADLDTPGSTRSTAYDRAWWFTRYVADAYG
TH_1112|M.thermoresistible__bu --------TDAEAQATRLPTDDDLDTPGPVRAHAYDRAWWFSSYVADRYG
MAB_1975|M.abscessus_ATCC_1997 AAPTLANALASGQVPDHLPTDEELDNAGTRRTQAYEEAWSVAQYVAETFG
:*:* :: .*. * **:.** .: .:* :*
Mflv_2960|M.gilvum_PYR-GCK EDTLRALYVAACGHGHADFDGAVRTVLGVEPASLWADS----------
Mvan_3551|M.vanbaalenii_PYR-1 VEKLRALYVAACGHGHADVDTAVREVLGADLSTLSASPR---------
Rv2189c|M.tuberculosis_H37Rv TAKLRELYLATCGVGHFDLATAAHDVLGIDAAGLLARWQRWLMG----
Mb2212c|M.bovis_AF2122/97 TAKLRELYLATCGVGHFDLATAAHDVLGIDAAGLLARWQRWLMG----
MAV_2305|M.avium_104 PPKLRELYLATCGLRRADLATAAQEVLGTSPAGLLTRWHQWLTH----
MMAR_3233|M.marinum_M TTKLRDLYLAACGPGHSDLPRAALEVLGTDAAGLLAGWQQWMSVSS--
MSMEG_4255|M.smegmatis_MC2_155 PAKLRDLYVRACGFDHPDIATAVRTSLGAELDAVVDGWRRWMSG----
TH_1112|M.thermoresistible__bu PAALRDLYLRACGPGHRDVATAVRDALGAEPDVVLAGWRRWLTD----
MAB_1975|M.abscessus_ATCC_1997 EPRLVRLYRDGAGLAPQPRGAAIQRALGVDEATLVRQWQGWLGSRRLR
* ** .* * ** . :