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M. tuberculosis H37Rv Rv2122c (hisE)

annotation: phosphoribosyl-ATP pyrophosphatase
coordinates: 2380663 - 2380944
length: 93

QQSLAVKTFEDLFAELGDRARTRPADSTTVAALDGGVHALGKKLLEEAGEVWLAAEHESNDALAEEISQL
LYWTQVLMISRGLSLDDVYRKL*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv2122chisE-100% (93)phosphoribosyl-ATP pyrophosphatase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2146chisE3e-48100.00% (93) phosphoribosyl-ATP pyrophosphatase
M. gilvum PYR-GCKMflv_3056hisE4e-3982.80% (93) phosphoribosyl-ATP pyrophosphatase
M. leprae Br4923MLBr_01309hisE4e-4387.10% (93) phosphoribosyl-ATP pyrophosphatase
M. abscessus ATCC 19977MAB_2131-8e-3780.46% (87) phosphoribosyl-ATP pyrophosphatase
M. marinum MMMAR_3104hisE2e-4288.17% (93) phosphoribosyl-AMP pyrophosphatase HisE
M. avium 104MAV_2392hisE2e-4390.32% (93) phosphoribosyl-ATP pyrophosphatase
M. smegmatis MC2 155MSMEG_4181hisE3e-3878.49% (93) phosphoribosyl-ATP pyrophosphatase
M. thermoresistible (build 8)TH_0038hisI3e-3982.42% (91) Probable phosphoribosyl-AMP pyrophosphatase HisE
M. ulcerans Agy99MUL_2353hisE1e-4288.17% (93) phosphoribosyl-ATP pyrophosphatase
M. vanbaalenii PYR-1Mvan_3471hisE8e-3982.80% (93) phosphoribosyl-ATP pyrophosphatase

CLUSTAL 2.0.9 multiple sequence alignment


Rv2122c|M.tuberculosis_H37Rv        MQQSLAVKTFEDLFAELGDRARTRPADSTTVAALDGGVHALGKKLLEEAG
Mb2146c|M.bovis_AF2122/97           MQQSLAVKTFEDLFAELGDRARTRPADSTTVAALDGGVHALGKKLLEEAG
MMAR_3104|M.marinum_M               MKQSLAVKTFEDLFAELGDRARTRPPGSATVAALDAGVHTLGKKVLEEAG
MUL_2353|M.ulcerans_Agy99           MKQSLAVKTFEDLFAELGDRARTRPPGSATVAALDAGVHTLGKKVLEEAG
MLBr_01309|M.leprae_Br4923          MKQSLAVKTFEDLFAELSERARTRPTDSATVASLDGGIHALGKKILEEAG
MAV_2392|M.avium_104                MKQSLAVKTFEDLFAELGERARTRPAGSATVAALDGGVHGLGKKILEEAG
Mflv_3056|M.gilvum_PYR-GCK          MTQSSNVKTFDALFAELSERARTRPAGSGTVAALDGGVHGIGKKILEEAG
Mvan_3471|M.vanbaalenii_PYR-1       MTQSPNVKTFDALFAELSERARTRPAGSGTVAALDGGVHGIGKKILEEAG
MSMEG_4181|M.smegmatis_MC2_155      MKQFMLVKTFDALFAELSDKARTRPAGSGTVAALDAGVHGIGKKILEEAG
TH_0038|M.thermoresistible__bu      MGQSIIVKTFDALFAELSDKARTRPAGSGTVAALDAGVHGIGKKVLEEAG
MAB_2131|M.abscessus_ATCC_1997      ------MKTFDELFAELSDRAKTRPEGSGTVAALDAGVHTLGKKLLEEAG
                                          :***: *****.::*:*** .* ***:**.*:* :***:*****

Rv2122c|M.tuberculosis_H37Rv        EVWLAAEHESNDALAEEISQLLYWTQVLMISRGLSLDDVYRKL
Mb2146c|M.bovis_AF2122/97           EVWLAAEHESNDALAEEISQLLYWTQVLMISRGLSLDDVYRKL
MMAR_3104|M.marinum_M               EVWLAAEHESNEALAEEISQLLYWTQVLMISRGVSLDEVYRKL
MUL_2353|M.ulcerans_Agy99           EVWLAAEHESNEALAEEISQLLYWTQVLMISRGVSLDEVYRKL
MLBr_01309|M.leprae_Br4923          EVWLAAEHEPKEVLAEEISQLLYWTQVLMISRGLSLDDVYRKL
MAV_2392|M.avium_104                EVWLAAEHESDDALAGEISQLLYWTQVLMIARGLSLDDVYRKL
Mflv_3056|M.gilvum_PYR-GCK          EVWLAAEHESDDALAEEISQLLYWTQVLMLARGLSLDDVYGKL
Mvan_3471|M.vanbaalenii_PYR-1       EVWLAAEHESDEALAEEISQLLYWTQVLMLSRGLSLDDVYGKL
MSMEG_4181|M.smegmatis_MC2_155      EVWLAAEHEGDEALAEEISQLLYWTQVLMVSRGLTLDDVYRKL
TH_0038|M.thermoresistible__bu      EVWLAAEHESDDALAEEISQLLYWTQVLMIARGITLDDVYRKL
MAB_2131|M.abscessus_ATCC_1997      EVWLAAEHESDESLAEEVSQLLYWAQVLLIARGLTLDDVYRKL
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