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MLVLHGFWSNSGGMRLWAEDSDLLVKSPSQALRSARPHPFAAPADLIAGIHPGKPATAVLLLPSLRSAPL DSPELIRLAPRPAARTDPMLLAWTVPVVDLDPTAALAAFDQPAPDVRYGASVDYLAELAVFARELVERGR VLPQLRRDTHGAAACWRPVLQGRDVVAMTSLVSAMPPVCRAEVGGHDPHELATSALDAMVDAAVRAALSP MDLLPPRRGRSKRHRAVEAWLTALTCPDGRFDAEPDELDALAEALRPWDDVGIGTVGPARATFRLSEVET ENEETPAGSLWRLEFLLQSTQDPSLLVPAEQAWNDDGSLRRWLDRPQELLLTELGRASRIFPELVPALRT ACPSGLELDADGAYRFLSGTAAVLDEAGFGVLLPSWWDRRRKLGLVLSAYTPVDGVVGKASKFGREQLVE FRWELAVGDDPLSEEEIAALTETKSPLIRLRGQWVALDTEQMRRGLEFLERKPTGRKTTAEILALAASHP DDVDTPLEVTAVRADGWLGDLLAGAAAASLQPLDPPDGFTATLRPYQQRGLAWLAFLSSLGLGSCLADDM GLGKTVQLLALETLESVQRHQDRGVGPTLLLCPMSLVGNWPQEAARFAPNLRVYAHHGGARLHGEALRDH LERTDLVVSTYTTATRDIDELAEYEWNRVVLDEAQAVKNSLSRAAKAVRRLRAAHRVALTGTPMENRLAE LWSIMDFLNPGLLGSSERFRTRYAIPIERHGHTEPAERLRASTRPYILRRLKTDPAIIDDLPEKIEIKQY CQLTTEQASLYQAVVADMMEKIENTEGIERRGNVLAAMAKLKQVCNHPAQLLHDRSPVGRRSGKVIRLEE ILEEILAEGDRVLCFTQFTEFAELLVPHLAARFGRAARDIAYLHGGTPRKRRDEMVARFQSGDGPPIFLL SLKAGGTGLNLTAANHVVHLDRWWNPAVENQATDRAFRIGQRRTVQVRKFICTGTLEEKIDEMIEEKKAL ADLVVTDGEGWLTELSTRDLREVFALSEGAVGE
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. tuberculosis H37Rv | Rv2101 | helZ | - | 100% (1013) | PROBABLE HELICASE HELZ |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2127 | helZ | 0.0 | 99.70% (1013) | helicase HelZ |
M. gilvum PYR-GCK | - | - | - | - | - |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | - | - | - | - | - |
M. marinum M | - | - | - | - | - |
M. avium 104 | - | - | - | - | - |
M. smegmatis MC2 155 | MSMEG_1196 | - | 3e-15 | 23.72% (506) | SNF2 domain-containing protein |
M. thermoresistible (build 8) | TH_3552 | - | 1e-29 | 27.92% (462) | PUTATIVE putative helicase domain protein |
M. ulcerans Agy99 | - | - | - | - | - |
M. vanbaalenii PYR-1 | Mvan_1096 | - | 9e-09 | 28.87% (194) | helicase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment Rv2101|M.tuberculosis_H37Rv -------------------------------------------------- Mb2127|M.bovis_AF2122/97 -------------------------------------------------- MSMEG_1196|M.smegmatis_MC2_155 -------------------------------------------------- TH_3552|M.thermoresistible__bu MIEKRLTEQLLETGELTLTEKECQSLELPQHSTTVELELEGEAFTAQWTG Mvan_1096|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv2101|M.tuberculosis_H37Rv -------------------------------------------------- Mb2127|M.bovis_AF2122/97 -------------------------------------------------- MSMEG_1196|M.smegmatis_MC2_155 -------------------------------------------------- TH_3552|M.thermoresistible__bu RGRVLSGDFLAERLQDYGQVNGLLRLRRVDDIYRLQLLPPGTQFTITVPP Mvan_1096|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv2101|M.tuberculosis_H37Rv -------------------------------------------------- Mb2127|M.bovis_AF2122/97 -------------------------------------------------- MSMEG_1196|M.smegmatis_MC2_155 -------------------------------------------------- TH_3552|M.thermoresistible__bu PPPPRVTSSRKAKTQRRRATVDRQFHADSDYDWGQRSTPTIGFLTEAREL Mvan_1096|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv2101|M.tuberculosis_H37Rv -------------------------------------------------- Mb2127|M.bovis_AF2122/97 -------------------------------------------------- MSMEG_1196|M.smegmatis_MC2_155 -------------------------------------------------- TH_3552|M.thermoresistible__bu LSEQLKAAGFDTRELVELRRQGEKLATLDDFEELLSVDVSNVDKMPHQEA Mvan_1096|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv2101|M.tuberculosis_H37Rv -------------------------------------------------- Mb2127|M.bovis_AF2122/97 -------------------------------------------------- MSMEG_1196|M.smegmatis_MC2_155 -------------------------------------------------- TH_3552|M.thermoresistible__bu VARHALSRLRGRAILADEVGLGKTIEAGLAVKELTLRGLAKRVLILCPAP Mvan_1096|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv2101|M.tuberculosis_H37Rv -------------------------------------------------- Mb2127|M.bovis_AF2122/97 -------------------------------------------------- MSMEG_1196|M.smegmatis_MC2_155 -------------------------------------------------- TH_3552|M.thermoresistible__bu LREQWREEMGHKFDLNFEVATRGPEIQKQDKLIMSLQLARSNIDKLTRKP Mvan_1096|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv2101|M.tuberculosis_H37Rv -------------------------------------------------- Mb2127|M.bovis_AF2122/97 -------------------------------------------------- MSMEG_1196|M.smegmatis_MC2_155 -------------------------------------------------- TH_3552|M.thermoresistible__bu WDIVILDEAHRAAGSHSVKTRILITSLTTACRYAFFLTATPVQNDLLELY Mvan_1096|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv2101|M.tuberculosis_H37Rv ----MLVLHGFWSNSGGMRLWAEDSDLLVKSPSQ------ALRSARPHPF Mb2127|M.bovis_AF2122/97 ----MLVLHGFWSNSGGMRLWAEDSDLLVKSPSQ------ALRSARPHPF MSMEG_1196|M.smegmatis_MC2_155 ---------------------MDRADLVRRADGL------LADLG----- TH_3552|M.thermoresistible__bu RLVELLRPGTFTSASDFRRQFMSPYDTRTPADPAGLRRLISSVMVRTTRA Mvan_1096|M.vanbaalenii_PYR-1 ------MLPGFAHLSPGSRVEGLAFDAVVEIVDITAAGSGAFVRYRDEFG * Rv2101|M.tuberculosis_H37Rv AAPADLIAGIHPGKPATAVLLLPSLRSAPLDSPELIRLAPRPAARTDPML Mb2127|M.bovis_AF2122/97 AAPADLIAGIHPGKPATAVLLLPSLRSAPLDSPELIRLAPRPAARTDPML MSMEG_1196|M.smegmatis_MC2_155 TLRAEIAANVRAN---TDAVVERALQSTPLAG---VRPYLTLGTRISALL TH_3552|M.thermoresistible__bu QAGVDRVVRRAVNEAITLGSREQELYALATELLRKVMRDPSDAMRRRSLA Mvan_1096|M.vanbaalenii_PYR-1 IEDSRLISADELKKILPVGRRGPTLAADPDQFWLAIEALRLRHAAVLNPL . * : . : Rv2101|M.tuberculosis_H37Rv LAWTVPVVDLDPTAALAAFDQP--------------APDVRYGAS----- Mb2127|M.bovis_AF2122/97 LAWTVPVVDLDPTAALAAFDQP--------------APDVRYGAS----- MSMEG_1196|M.smegmatis_MC2_155 NSEYRTVADVHTVPARLLTQVP--------------GVDIATAQA----- TH_3552|M.thermoresistible__bu LRLTASPFSMGTTALRMADRHPDSRVRKVLREIGHLAMDIKTSAREDRAL Mvan_1096|M.vanbaalenii_PYR-1 LAVSSSNVEALPHQVQAVYDCM---------------------------- . . . Rv2101|M.tuberculosis_H37Rv ------VDYLAELAVFARELVERGRVLPQLRRDTHGAAACWRPVLQGRDV Mb2127|M.bovis_AF2122/97 ------VDYLAELAVFARELVERGRVLPQLRRDTHGAAACWRPVLQGRDV MSMEG_1196|M.smegmatis_MC2_155 ------VQAGAQLMADRIRTTTR----PRLDRESESDTALLADLLVLIKA TH_3552|M.thermoresistible__bu EITRNWLREHGRVLIFTQHTDTVTGLLRRLEAEGLTARSFHGSMSATERA Mvan_1096|M.vanbaalenii_PYR-1 ------LTGHPKRFLLADDPGAGKTIMAGLFIKEALARGWIRRCLIVVPG : . * . . Rv2101|M.tuberculosis_H37Rv VAMTSLVSAMPPVCRAEVGGHDPHELATSALDAMVDAAVRAALSPMDLLP Mb2127|M.bovis_AF2122/97 VAMTSLVSAMPPVCRAEVGGHDPHELATSALDAMVDAAVRAALSPMDLLP MSMEG_1196|M.smegmatis_MC2_155 TPPAKQLRRILPRVRARVEAPN---------------------------- TH_3552|M.thermoresistible__bu KTIAAFRSGEAPIMISTDAGAEGQDLQFCNCVLNYDLPWNPMRVEQRIGR Mvan_1096|M.vanbaalenii_PYR-1 SLVEQWQNELREKFSLQFEVFENSLLGDSPDESLQNFPFLIARLDQFSRS : Rv2101|M.tuberculosis_H37Rv PRRGRSKRHRAVEAWLTAL---------------TCPDGRFDAEPDELDA Mb2127|M.bovis_AF2122/97 PRRGRSKRHRAVEAWLTAL---------------TCPDGRFDAEPDELDA MSMEG_1196|M.smegmatis_MC2_155 ---GNGRRRRTEAAAVEE------------------PDPLLDKVADLVER TH_3552|M.thermoresistible__bu VDRLTQPKDEVFVANLYAQNTIDEKVFWLLAEKLRMFELLFGQVTTILGE Mvan_1096|M.vanbaalenii_PYR-1 SELTARAVDGAYDLAIFDEAH-------------KLAVSSWGSTVTKTKR . : . Rv2101|M.tuberculosis_H37Rv LAEALRPWDDVGIGTVGPARATFRLSEVETENEETPAGSLWRLEFLLQST Mb2127|M.bovis_AF2122/97 LAEALRPWDDVGIGTVGPARATFRLSEVETENEETPAGSLWRLEFLLQST MSMEG_1196|M.smegmatis_MC2_155 IECARKPETDVWAG--------YRRDGAEIDR------------------ TH_3552|M.thermoresistible__bu LDESKSASFESRVMEALFAENDTKMNALLDQLGMELVQAREKASELIAAD Mvan_1096|M.vanbaalenii_PYR-1 FKLAEAIRDAVPSTLLMTATPHNGKDADYREFLTLLGSADQPVVEDPAGN : : . : Rv2101|M.tuberculosis_H37Rv QDPSLLVPAEQAWNDDGSLRRWLDRPQELLLTELGRASRIFPELVPALRT Mb2127|M.bovis_AF2122/97 QDPSLLVPAEQAWNDDGSLRRWLDRPQELLLTELGRASRIFPELVPALRT MSMEG_1196|M.smegmatis_MC2_155 -----------------------------LLMEFASG------------- TH_3552|M.thermoresistible__bu RDVSKWMAGAFEHRKGLTKAGSTELAPEVARRARMRQRRVQTWVRNVLKA Mvan_1096|M.vanbaalenii_PYR-1 GLMRRLVKEQLVHLDGTPLFPERRASTVPYRLSPIESELYEAVSEYVREE Rv2101|M.tuberculosis_H37Rv ACPSGLELDADGAYRFLSGTAAVLDEAGFGVLLPSWWDRRRK-------- Mb2127|M.bovis_AF2122/97 ACPSGLELDADGAYRFLSGTAAVLDEAGFGVLLPSWWDRRRK-------- MSMEG_1196|M.smegmatis_MC2_155 ------TTDVDAAQGFVG--AAVAEEA----------------------- TH_3552|M.thermoresistible__bu LNADIIHDTGDGEGAFITAVFSEEFEQELGGRTTMHLAFDRFGLEHHPEA Mvan_1096|M.vanbaalenii_PYR-1 MNKVSDDDTRRSVGFALVVLQRRLASSPQAILRSLTRRRDR--------- . : . Rv2101|M.tuberculosis_H37Rv ---------------------------------LGLVLSAYTPVDGVVGK Mb2127|M.bovis_AF2122/97 ---------------------------------LGLVLSAYTPVDGVVGK MSMEG_1196|M.smegmatis_MC2_155 -------------------------------------------------- TH_3552|M.thermoresistible__bu ELCAVGSPVFDELLGLLRVRGDIHATVPVIPEDIGPTPYRYSDSIRLVRR Mvan_1096|M.vanbaalenii_PYR-1 ---------------------------------LRAQADQAHATEGKLAA Rv2101|M.tuberculosis_H37Rv ASKFGREQLVEFRWELAVGDDPLSEEEIAALTETKSPLIRLRGQWVALDT Mb2127|M.bovis_AF2122/97 ASKFGREQLVEFRWELAVGDDPLSEEEIAALTETKSPLIRLRGQWVALDT MSMEG_1196|M.smegmatis_MC2_155 -------------------------------------------------- TH_3552|M.thermoresistible__bu RLVPSGSWSGQATFRATVGEAETTEHLITADINSHREHLLPRRPLEDGES Mvan_1096|M.vanbaalenii_PYR-1 SLAATLGLGSDDPDEMSSLRAETYQDEVVSVATNARTPAELEAEILVLDR Rv2101|M.tuberculosis_H37Rv EQMRRGLEFLERKPTGRKTTAEILALAASHPDDVDTPLEVTAVRADGWLG Mb2127|M.bovis_AF2122/97 EQLRRGLEFLERKPTGRKTTAEILALAASHPDDVDTPLEVTAVRADGWLG MSMEG_1196|M.smegmatis_MC2_155 -----------------------------AQIDVDRSLVRTELRGYQLFG TH_3552|M.thermoresistible__bu LPPAFGTAPQVIARFERAAIPQLESLRRERLDEVERQQALELERVTSGYR Mvan_1096|M.vanbaalenii_PYR-1 LVIKAEAVYSARADAKWAALAELLTSEAMFEADRQRRKIIIFSENRDTLD : : . Rv2101|M.tuberculosis_H37Rv DLLAG----------------AAAASLQPLDPPDGFTATLRPYQQRGLAW Mb2127|M.bovis_AF2122/97 DLLAG----------------AAAASLQPLDPPDGFTATLRPYQQRGLAW MSMEG_1196|M.smegmatis_MC2_155 AQYAL----------------ARRR------------------------- TH_3552|M.thermoresistible__bu AQIAESSGDERARLQRALRTEEKRLTRRPDIRARAKVLAVTLDEDDWLVE Mvan_1096|M.vanbaalenii_PYR-1 YLEDR------------------------------------------LVE Rv2101|M.tuberculosis_H37Rv LAFLSSLGLGSCLADDMGLGKTVQLLALET-------------------- Mb2127|M.bovis_AF2122/97 LAFLSSLGLGSCLADDMGLGKTVQLLALET-------------------- MSMEG_1196|M.smegmatis_MC2_155 ----------VLLCDELGLGKTLQALTVAA-------------------- TH_3552|M.thermoresistible__bu ETWAGPSGDETTLTYEWGVERPIIESAVTGGPIGVLALCSDMHWVDESEV Mvan_1096|M.vanbaalenii_PYR-1 LLGRTVDVQVIHGAMSWTDRRRAQANFIAE-------------------- . : : Rv2101|M.tuberculosis_H37Rv --LESVQRHQDRGVGPTLLLCPMSLVGNWPQEAARFAPNLRVYAHHGGAR Mb2127|M.bovis_AF2122/97 --LESVQRHQDRGVGPTLLLCPMSLVGNWQQEAARFAPNLRVYAHHGGAR MSMEG_1196|M.smegmatis_MC2_155 --HLAAAETMR----HTLVICPANTGIHWAEETLKHT---WLTPLEIRGR TH_3552|M.thermoresistible__bu TRCGSCERSLCDACGEDAVFAACAVCAQWCCGRCRRETGGLCRTCASPQR Mvan_1096|M.vanbaalenii_PYR-1 --PSSSVLIATDAAGEGVNLQVAHLMVNYDVPWNPNRLEQRFGRIHRIGQ : : :: : Rv2101|M.tuberculosis_H37Rv L---HGEALRDHLERTDLVVSTYTTATRDIDELAEYEWNRVVLDEAQAVK Mb2127|M.bovis_AF2122/97 L---HGEALRDHLERTDLVVSTYTTATRDIDELSEYEWNRVVLDEAQAVK MSMEG_1196|M.smegmatis_MC2_155 R---REERLAEWKDKGGLAIVTFSALSKITLPERP---GLVIVDEAHLLR TH_3552|M.thermoresistible__bu VPELDDEFFVAWRLGGGNIVRVGERVAELVRPDGSPPAVLVSAQDYDDPR Mvan_1096|M.vanbaalenii_PYR-1 RHTCHLWNLVAADTREGDVFRTLLEKVEVQREALGDQVFDVLGEVLTEIS : . . . . * : Rv2101|M.tuberculosis_H37Rv NS----------------LSRAAKAVRRLRAAHR--VALTGTPMENRLAE Mb2127|M.bovis_AF2122/97 NS----------------LSRAAKAVRRLRAAHR--VALTGTPMENRLAE MSMEG_1196|M.smegmatis_MC2_155 DP----------------KSDRARAVRNVLTADACVLFLSGVPLHNRIEG TH_3552|M.thermoresistible__bu MARLRAYAHQNGLPLDCGLVKRDLTVRDETPVSTRLRLHTSRTVAVELSI Mvan_1096|M.vanbaalenii_PYR-1 LS---------------QLLRRAVGGEAPRGEIASQLDSVSGRLESAVEK . . . : : Rv2101|M.tuberculosis_H37Rv LWSIMDFLNPGLLGSSERFRTRYAIPIERHGHTEPAERLRASTR------ Mb2127|M.bovis_AF2122/97 LWSIMDFLNPGLLGSSERFRTRYAIPIERHGHTEPAERLRASTR------ MSMEG_1196|M.smegmatis_MC2_155 FRHLADFLQPDVATKVP----------PNAGAQGSVAFRRTADR------ TH_3552|M.thermoresistible__bu DSSLDAALDLDVVEAVPAAPEVPVSREEDFGLSVALTQMRREAPPPRRPA Mvan_1096|M.vanbaalenii_PYR-1 RAASVSTLTPEELAVLR----------REMEIAKAMSFQPDVAR------ * . Rv2101|M.tuberculosis_H37Rv -----------PYILRRLKTDPAIIDDLPEKIEIK-------QYCQLTTE Mb2127|M.bovis_AF2122/97 -----------PYILRRLKTDPAIIDDLPEKIEIK-------QYCQLTTE MSMEG_1196|M.smegmatis_MC2_155 -----------VYLRRDYR---DVVAELPQRISTD-------EWVRLTGE TH_3552|M.thermoresistible__bu VVVTHRAQFVDLYLETDRLVREELVVTNDKALTLTGTSSTDLQWVEPSVD Mvan_1096|M.vanbaalenii_PYR-1 -----------DFMVRAASLFHVDITMRGDAWQVG--------YVPTRLR :: : . : Rv2101|M.tuberculosis_H37Rv QASLYQAVVADMMEKIENTEGIERRGNVLAAMAKLKQVCNHPAQ------ Mb2127|M.bovis_AF2122/97 QASLYQAVVADMMEKIENTEGIERRGNVLAAMAKLKQVCNHPAQ------ MSMEG_1196|M.smegmatis_MC2_155 DRVRYRRAVD---------------GGNFSAIRQAAWPSGMPGP------ TH_3552|M.thermoresistible__bu HPLVAEGRLDDLHVSVERRNEALVVDARLGSASVGRWVACPDGTSIAEQV Mvan_1096|M.vanbaalenii_PYR-1 DQFGSSLMARYDRVAFEHSDDQVFAADPPELMAPGHPLVSALAD------ . . Rv2101|M.tuberculosis_H37Rv -----LLHDRSPVGRRSGKVIRLEEILEEILAEGDRVLCFTQFTEFAELL Mb2127|M.bovis_AF2122/97 -----LLHDRSPVGRRSGKVIRLEEILEEILAEGDRVLCFTQFTEFAELL MSMEG_1196|M.smegmatis_MC2_155 -----PGP--------SAKLDRLIELISEAHINGARVVVLSHFPGVLETI TH_3552|M.thermoresistible__bu SCYEHLQTLGTPGGRLGKQTYSIEEIVTSFPAPSECTAADRTIRVVAGTV Mvan_1096|M.vanbaalenii_PYR-1 ----------------AAGEEFGSSLNHGIVLSDNRSSDDYVLVTVVATA . .: . : . Rv2101|M.tuberculosis_H37Rv VP-----------HLAARFGRAARDIAYLHGGTPRKRRDEMVARFQ---- Mb2127|M.bovis_AF2122/97 VP-----------HLAARFGRAARDIAYLHGGTPRKRRDEMVARFQ---- MSMEG_1196|M.smegmatis_MC2_155 RK-----------ALPG------TVFGPLDESVPD--RQAMLDAFA---- TH_3552|M.thermoresistible__bu PTTKDTDVVPADTESLAALGISPANRAPSAEPVPRDLAKDLLDRAARSYT Mvan_1096|M.vanbaalenii_PYR-1 EG------------NPSTVTTYAVTVGGDRQQVSPGLYTDLEMGAT---- . . .. : Rv2101|M.tuberculosis_H37Rv ------------------------SGDGPPIFLLSLKAGGTGLN------ Mb2127|M.bovis_AF2122/97 ------------------------SGDGPPIFLLSLKAGGTGLN------ MSMEG_1196|M.smegmatis_MC2_155 ------------------------TARGPATLLAQLDVGPLDLRR----- TH_3552|M.thermoresistible__bu AAIRNGLEVTETWRGHGTATHVYRTFDGQPLSPNLDDIGARHSDFGVCRD Mvan_1096|M.vanbaalenii_PYR-1 -------------------------PEPREVAAAEAAVAAFSDDPD---- . Rv2101|M.tuberculosis_H37Rv -----------------------LTAANHVVHLDRWWNPAVENQATDRAF Mb2127|M.bovis_AF2122/97 -----------------------LTAANHVVHLDRWWNPAVENQATDRAF MSMEG_1196|M.smegmatis_MC2_155 -----------------------LSMPLVAIVTEPQWQPRAERRMIGRTQ TH_3552|M.thermoresistible__bu GHFYAAGTAALCEACHTWACRACDMLEHRASVECPGCAHAVCRRCVASVH Mvan_1096|M.vanbaalenii_PYR-1 -----------------------RDIAAVAYVRGTASPETADGWRAARGQ . . Rv2101|M.tuberculosis_H37Rv RIGQRRTVQVRKFICTGTLEEK-----------------IDEMIEEKKAL Mb2127|M.bovis_AF2122/97 RIGQRRTVQVRKFICTGTLEEK-----------------IDEMIEEKKAL MSMEG_1196|M.smegmatis_MC2_155 RLSDLHTVRVHRLLARGSIDEP-----------------IRRLAHHPDEP TH_3552|M.thermoresistible__bu SVPKTRCLLCGDRACPDCGRDPDVAACVMCDRAMCGSCRIGDTCPACSRL Mvan_1096|M.vanbaalenii_PYR-1 LRDELTARGLDPVAALPGQGWDFTTG--------------ADVIMFWSAA . . . Rv2101|M.tuberculosis_H37Rv ADLVVTDGEGWLTELSTRDLREVFALSEGAVGE----------------- Mb2127|M.bovis_AF2122/97 ADLVVTDGEGWLTELSTRDLREVFALSEGAVGE----------------- MSMEG_1196|M.smegmatis_MC2_155 PPHQDEMVRAEQTRLARLDRMR---------------------------- TH_3552|M.thermoresistible__bu APATDDERRSLPDALAVEGASLLIASDEDATVVLIDRGSAREQAIIRDGS Mvan_1096|M.vanbaalenii_PYR-1 PPGEMERRRAEKHVAANVGGKYRVALG----------------------- . .. : . Rv2101|M.tuberculosis_H37Rv -------------------------------------------------- Mb2127|M.bovis_AF2122/97 -------------------------------------------------- MSMEG_1196|M.smegmatis_MC2_155 -------------------------------------------------- TH_3552|M.thermoresistible__bu VNRWVAFDRTQIDSAYRLRLAASRALKFPVVPRVELLKPEVPHPGPRILL Mvan_1096|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv2101|M.tuberculosis_H37Rv -------------------------------------------------- Mb2127|M.bovis_AF2122/97 -------------------------------------------------- MSMEG_1196|M.smegmatis_MC2_155 -------------------------------------------------- TH_3552|M.thermoresistible__bu RSDRRFYPAWSAATLAGRDPEGRPTPDDDLAAAVADQFPPLSSCPEPVIK Mvan_1096|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv2101|M.tuberculosis_H37Rv -------------------------------------------------- Mb2127|M.bovis_AF2122/97 -------------------------------------------------- MSMEG_1196|M.smegmatis_MC2_155 -------------------------------------------------- TH_3552|M.thermoresistible__bu APARLRPLLASLNPPPTTPMVIRWERVGSDVAVVPSGISVATIDGPNQHE Mvan_1096|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv2101|M.tuberculosis_H37Rv -------------------------------------------------- Mb2127|M.bovis_AF2122/97 -------------------------------------------------- MSMEG_1196|M.smegmatis_MC2_155 -------------------------------------------------- TH_3552|M.thermoresistible__bu AITEWREPDRPTEWISQSWNPVPAVRMTAADGEVEAALVSMGALVALGVH Mvan_1096|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv2101|M.tuberculosis_H37Rv -------------------------------------------------- Mb2127|M.bovis_AF2122/97 -------------------------------------------------- MSMEG_1196|M.smegmatis_MC2_155 -------------------------------------------------- TH_3552|M.thermoresistible__bu ISGRTDWYVVAASAHAPAATLLSRSMGLADADEVGTFTDPSRIRLSTIAN Mvan_1096|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv2101|M.tuberculosis_H37Rv -------------------------------------------------- Mb2127|M.bovis_AF2122/97 -------------------------------------------------- MSMEG_1196|M.smegmatis_MC2_155 -------------------------------------------------- TH_3552|M.thermoresistible__bu ASSVSHDVTPRGELKPASARADHETAAALAAWCPDATVMTPPLLVMPDEL Mvan_1096|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv2101|M.tuberculosis_H37Rv -------------------------------------------------- Mb2127|M.bovis_AF2122/97 -------------------------------------------------- MSMEG_1196|M.smegmatis_MC2_155 -------------------------------------------------- TH_3552|M.thermoresistible__bu RIALRKVITPAQRYTLDIGASVVETVSTQDGQEWKYEVALAPGSTDARRL Mvan_1096|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv2101|M.tuberculosis_H37Rv -------------------------------------------------- Mb2127|M.bovis_AF2122/97 -------------------------------------------------- MSMEG_1196|M.smegmatis_MC2_155 -------------------------------------------------- TH_3552|M.thermoresistible__bu DHITRQTLDWGGIDREGHFGTAHVMCGYCNQICCSACTDGMVACDCCGAP Mvan_1096|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv2101|M.tuberculosis_H37Rv -------------------------------------------------- Mb2127|M.bovis_AF2122/97 -------------------------------------------------- MSMEG_1196|M.smegmatis_MC2_155 -------------------------------------------------- TH_3552|M.thermoresistible__bu ICKRCVREPSAGTYLCHACASMRPPTRQEARNHGRLLFTRGMLIGIDPLH Mvan_1096|M.vanbaalenii_PYR-1 -------------------------------------------------- Rv2101|M.tuberculosis_H37Rv ---------------------------------------------- Mb2127|M.bovis_AF2122/97 ---------------------------------------------- MSMEG_1196|M.smegmatis_MC2_155 ---------------------------------------------- TH_3552|M.thermoresistible__bu TVVVERAKPRWELHVGNGEKQAIANPSVLRHLDQRLAGADDQEQGG Mvan_1096|M.vanbaalenii_PYR-1 ----------------------------------------------