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M. tuberculosis H37Rv Rv2067c (-)

annotation: hypothetical protein Rv2067c
coordinates: 2324647 - 2325870
length: 407

TDDHPRADIVSRQYHRWLYPHPIADLEAWTTANWEWFDPVHSHRILWPDREYRPDLDILIAGCGTNQAAI
FAFTNRAAKVVAIDISRPALDHQQYLKDKHGLANLELHLLPIEELATLGRDFDLVVSTGVLHHLADPRAG
MKELAHCLRRDGVVAAMLYGKYGRIGVELLGSVFRDLGLGQDDASIKLAKEAISLLPTYHPLRNYLTKAR
DLLSDSALVDTFLHGRQRSYTVEECVDLVTSAGLVFQGWFHKAPYYPHDFFVPNSEFYAAVNTLPEVKAW
SVMERLETLNATHLFMACRRDRPKEQYTIDFSTVAALDYVPLMRTRCGVSGTDMFWPGWRMAPSPAQLAF
LQQVDGRRTIREIAGCVARTGEPSGGSLADLEEFGRKLFQSLWRLDFVAVALPASG*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv2067c--100% (407)hypothetical protein Rv2067c

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2093c-0.0100.00% (407) hypothetical protein Mb2093c
M. gilvum PYR-GCK-----
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum MMMAR_3047-0.078.80% (401) hypothetical protein MMAR_3047
M. avium 104MAV_1181-1e-14963.16% (399) hypothetical protein MAV_1181
M. smegmatis MC2 155-----
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_2291-0.078.30% (401) hypothetical protein MUL_2291
M. vanbaalenii PYR-1Mvan_4620-1e-0529.41% (102) methyltransferase type 11

CLUSTAL 2.0.9 multiple sequence alignment


Rv2067c|M.tuberculosis_H37Rv       MTDDHPRADIVSRQYHRWLYPHPIADLEAWTTANWEWFDPVHSHRILWPD
Mb2093c|M.bovis_AF2122/97          MTDDHPRADIVSRQYHRWLYPHPIADLEAWTTANWEWFDPVHSHRILWPD
MMAR_3047|M.marinum_M              MNDD-PRADIVSRQYQRWVYPHPIEDLPAWTSANWEWFDPVYSHRILWPD
MUL_2291|M.ulcerans_Agy99          MNDD-PRADIVSRQYQRWVYPHPIEDLPAWTSANWEWFDPVYSHRILWPD
MAV_1181|M.avium_104               MSED-ARADGVSRQYDRWQYPPPVTDLDAWTTNHWDWFDPFWAHRLLWPD
Mvan_4620|M.vanbaalenii_PYR-1      -----MSFVVASEAYGRFMG---------------RYAEPLAEAFVAFAG
                                             .*. * *:                  : :*.    : :..

Rv2067c|M.tuberculosis_H37Rv       REYRPDLDILIAGCGTNQAAIFAFTNRAAKVVAIDISRPALDHQQYLKDK
Mb2093c|M.bovis_AF2122/97          REYRPDLDILIAGCGTNQAAIFAFTNRAAKVVAIDISRPALDHQQYLKDK
MMAR_3047|M.marinum_M              RAYQPDLDILIAGCGTNQAAIFAFTNRSAKVVAVDVSQTSLDHQQYLKDK
MUL_2291|M.ulcerans_Agy99          RAYQPDLDILIAGCGTNQAAIFAFTNRSAKVVAVDVSQTSLDHQQYLKDK
MAV_1181|M.avium_104               RDYRPGLDILIAGCGTFQAAVYAYTNRAAKVVAIDVSRTALDHQQFLKDK
Mvan_4620|M.vanbaalenii_PYR-1      --VGVGDKVLDVGCGP-GALTARLRSVGADIAAIDPSPPFIDAIR-----
                                        . .:* .***.  *      . .*.:.*:* * . :*  :     

Rv2067c|M.tuberculosis_H37Rv       HGLANLELHLLPIEELATLGRDFDLVVSTGVLHHLADPRAGMKELAHCLR
Mb2093c|M.bovis_AF2122/97          HGLANLELHLLPIEELATLGRDFDLVVSTGVLHHLADPRAGMKELAHCLR
MMAR_3047|M.marinum_M              YGLTNLELHLLPIEDLHTLGRDFDLVVSSGVLHHMADPLTGMKALAGCLR
MUL_2291|M.ulcerans_Agy99          YGLTNLELHLLPIEDLHTLGRDFDLVVSSGVLHHMADPLTGMKALAGCLR
MAV_1181|M.avium_104               HRLHNLELHRLAIEEVAALDRDFDLIVSTGVLHHLADPLTGLTALGRCLR
Mvan_4620|M.vanbaalenii_PYR-1      RSFPDVDVRQGPAEELPYDSAAFDAALAQLVVHFMTDPVAGLRQMSRVTR
                                     : :::::  . *::   .  **  ::  *:*.::** :*:  :.   *

Rv2067c|M.tuberculosis_H37Rv       RDGVVAAMLYGKYGRIGVELLGSVFRDLGLGQDDASIKLAKEAISLLPTY
Mb2093c|M.bovis_AF2122/97          RDGVVAAMLYGKYGRIGVELLGSVFRDLGLGQDDASIKLAKEAISLLPTY
MMAR_3047|M.marinum_M              PDGVVAAMLYGKYGRIGVDLLDSVFRDLGLGQDDVSVTMVKEAIALMPPY
MUL_2291|M.ulcerans_Agy99          PDGVVAAMLYGKYGRIGVDLLDSVFRDLGLGQDDVSVTMVKEAIALMPPY
MAV_1181|M.avium_104               PDGVLGVMLYASYGRIGVEMLASVFRDLGLSQDEASVELVKEAVAALPAD
Mvan_4620|M.vanbaalenii_PYR-1      PGGVVAACVWDGP--------------------TGALAPFWDAVHVVDPE
                                    .**:.. ::                         ::    :*:  : . 

Rv2067c|M.tuberculosis_H37Rv       HPLRNYLTKARDLLSDSALVDTFLHGRQRSYTVEECVDLVTSAGLVFQGW
Mb2093c|M.bovis_AF2122/97          HPLRNYLTKARDLLSDSALVDTFLHGRQRSYTVEECVDLVTSAGLVFQGW
MMAR_3047|M.marinum_M              HPVQNYLKKARDLTSDAALVDTFLHGRQRSYTVEECVDLVADAGLVFQGW
MUL_2291|M.ulcerans_Agy99          HPVQNYLKKARDLTSDAALVDTFLHGRQRSYTVEECVDLVADAGLVFQGW
MAV_1181|M.avium_104               HPVHTYLKGARDLSTDGGLVDTFLHARQRSYTVEQCLELVAAAGLAFQGW
Mvan_4620|M.vanbaalenii_PYR-1      AEDEALLSGAR----SGHLTELFEAAGLRDVVEDSIAVDVVHP--TFEQW
                                      .  *. **    .. *.: *  .  *. . :.    *. .  .*: *

Rv2067c|M.tuberculosis_H37Rv       FHKAPYYPHDFFVP--NSEFYAAVNTLPEVKAWSVMERLETLNATHLFMA
Mb2093c|M.bovis_AF2122/97          FHKAPYYPHDFFVP--NSEFYAAVNTLPEVKAWSVMERLETLNATHLFMA
MMAR_3047|M.marinum_M              FQKTPYYPHDFFVP--NSKFYAAVNALPEPKLWSVMERVETLNGVHLFMA
MUL_2291|M.ulcerans_Agy99          FQKTPYYPHDFFVP--NSKFYAAVNALPEPKLWSVMEHVETLNGVHLFMA
MAV_1181|M.avium_104               LRNSPYYPHDALFGSAATQFQSALNRLPDTTLWSVMERLQPANATHFFLA
Mvan_4620|M.vanbaalenii_PYR-1      WEPYTYGVG---------------------PAGDYVQQLDDEGRARLESA
                                    .  .*                           . :::::  . .::  *

Rv2067c|M.tuberculosis_H37Rv       CRRDRPKEQYTIDFSTVAALDYVPLMRTRCGVSGTDMFWPGWRMAPSPAQ
Mb2093c|M.bovis_AF2122/97          CRRDRPKEQYTIDFSTVAALDYVPLMRTRCGVSGTDMFWPGWRMAPSPAQ
MMAR_3047|M.marinum_M              CHPDRPKESYTIDFSAADALDYVPVLRTRCAVSGNEMIWPGFQMTPKPEQ
MUL_2291|M.ulcerans_Agy99          CHPDRPKESYTIDFSAADALDYVPVLRTHCAVSGSEMIWPGFQMTPKPEQ
MAV_1181|M.avium_104               CRPERPRERYRIDFSSPTYLGYVPLLRTACLLSGDQIHLPGAKLTLTPAQ
Mvan_4620|M.vanbaalenii_PYR-1      ARERLGKGPFTVTAVAWAARGTA---------------------------
                                   .:    :  : :   :    . .                           

Rv2067c|M.tuberculosis_H37Rv       LAFLQQVDGRRTIREIAGCVARTGEPSGGSLADLEEFGRKLFQSLWRLDF
Mb2093c|M.bovis_AF2122/97          LAFLQQVDGRRTIREIAGCVARTGEPSGGSLADLEEFGRKLFQSLWRLDF
MMAR_3047|M.marinum_M              LAFLRKVDGRRTIGEIAAGVAQSGEGPGGGIAELEEFGRHLFRSLWRLDF
MUL_2291|M.ulcerans_Agy99          LAFLRKVDGRRTIGEIAAGVAQSGEGPGGGIAELEEFGRHLFKSLWRLDF
MAV_1181|M.avium_104               LPFVQQVDGRRSIAEIIDGVAGAGRDD-----RAREFGRRLFDSLWRLDF
Mvan_4620|M.vanbaalenii_PYR-1      --------------------------------------------------
                                                                                     

Rv2067c|M.tuberculosis_H37Rv       VAVALPASG--
Mb2093c|M.bovis_AF2122/97          VAVALPASG--
MMAR_3047|M.marinum_M              IAVALNTGPAG
MUL_2291|M.ulcerans_Agy99          IAVALNTGPAG
MAV_1181|M.avium_104               LAMGLAPGR--
Mvan_4620|M.vanbaalenii_PYR-1      -----------