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M. tuberculosis H37Rv Rv2031c (hspX)

annotation: HEAT SHOCK PROTEIN HSPX (ALPHA-CRSTALLIN HOMOLOG) (14 kDa ANTIGEN) (HSP16.3)
coordinates: 2278498 - 2278932
length: 144

ATTLPVQRHPRSLFPEFSELFAAFPSFAGLRPTFDTRLMRLEDEMKEGRYEVRAELPGVDPDKDVDIMVR
DGQLTIKAERTEQKDFDGRSEFAYGSFVRTVSLPVGADEDDIKATYDKGILTVSVAVSEGKPTEKHIQIR
STN*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv2031chspX-100% (144)HEAT SHOCK PROTEIN HSPX (ALPHA-CRSTALLIN HOMOLOG) (14 kDa ANTIGEN) (HSP16.3)
M. tuberculosis H37RvRv0251chsp2e-1241.84% (98) heat shock protein hsp (heat-stress-induced ribosome-binding

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2057chspX1e-79100.00% (144) heat shock protein hspX
M. gilvum PYR-GCKMflv_1805-4e-1241.41% (99) heat shock protein Hsp20
M. leprae Br4923MLBr_01795hsp188e-0529.13% (103) 18 KDA antigen (HSP 16.7)
M. abscessus ATCC 19977MAB_4402-7e-1338.06% (134) heat shock protein Hsp20
M. marinum MMMAR_3484hspX_18e-5772.34% (141) heat shock protein HspX_1
M. avium 104MAV_4906-2e-1343.48% (92) Hsp20/alpha crystallin family protein
M. smegmatis MC2 155MSMEG_3932-2e-4660.84% (143) 14 kDa antigen
M. thermoresistible (build 8)TH_1239hspX2e-4662.14% (140) HEAT SHOCK PROTEIN HSPX (ALPHA-CRSTALLIN HOMOLOG) (14 kDa
M. ulcerans Agy99MUL_1178hsp3e-1041.98% (81) heat shock protein Hsp
M. vanbaalenii PYR-1Mvan_1374-2e-4660.87% (138) heat shock protein Hsp20

CLUSTAL 2.0.9 multiple sequence alignment


Rv2031c|M.tuberculosis_H37Rv        ---MATTLPVQRHPRSLFPEFSELFAAFPSFAGLRPTFDTRLMRLEDEMK
Mb2057c|M.bovis_AF2122/97           ---MATTLPVQRHPRSLFPEFSELFAAFPSFAGLRPTFDTRLMRLEDEMK
MMAR_3484|M.marinum_M               ---MG-TLSVQRPARSLFPEFSELFAAFPSFAGLRPAFDSRLMKLEDEMK
MSMEG_3932|M.smegmatis_MC2_155      ---MT-KLPERSRARSLFPEMSDFFAGLPSWASIRPVFGDHIIRIEDEMK
Mvan_1374|M.vanbaalenii_PYR-1       ---MN-NVAVQQPRRSAWPEVADFFAGFPSWANLRPMFGGHLIKVEDDIK
TH_1239|M.thermoresistible__bu      MKEMIMTTVERQRAKSLFPEIADFFAGFPSWPSLRPMFDTNLMRLEDELT
MAV_4906|M.avium_104                --MSNLALWTR-PAWDTDRWLRDFFGPAAAADWNKPATSAFKPAAEIVKD
MUL_1178|M.ulcerans_Agy99           --MSNLALWSR-PAWSTDRWLRDFFGPAAASDWYKPLATGFNPAAEIVKD
MAB_4402|M.abscessus_ATCC_1997      --MSNLVWTRRSPFAEFDALVRQSFGPATS--WPTP---GFVPSADVVKD
Mflv_1805|M.gilvum_PYR-GCK          --------MLRFDPFSDIDALTRGLLTSQTGSNRTP----RFMPMDLCKI
MLBr_01795|M.leprae_Br4923          -------MLMRTDPFRELDRFAEQVLG----TSARP----AVMPMDAWRE
                                              :         .   .          *         :    

Rv2031c|M.tuberculosis_H37Rv        EGRYEVRAELPGVDPDKDVDIMVRDGQLTIKAERTEQKDFDG-------R
Mb2057c|M.bovis_AF2122/97           EGRYEVRAELPGVDPDKDVDIMVRDGQLTIKAERTEQKDFDG-------R
MMAR_3484|M.marinum_M               GDRYELRAEIPGVDPEKDIEITVLDGQLTIKAERSEKKEFNG-------R
MSMEG_3932|M.smegmatis_MC2_155      DGGYELRAEVPGIDPAKDIDITVRDGVLTIKAERTEKKETNG-------R
Mvan_1374|M.vanbaalenii_PYR-1       DGKYELQAEIPGVDPEKDVDITVRDGVLTIKAERSEKKESNG-------R
TH_1239|M.thermoresistible__bu      DDKYMVRAEIPGVDPDKDIEITVQDGRLTIRAERQEKKETNG-------R
MAV_4906|M.avium_104                GDDAIVRVELPGVDVDQDVQVELDRGRLVIRGEHRDEHAEEK---DGRTL
MUL_1178|M.ulcerans_Agy99           GDDAVVRLELPGVDVENDVNVEVERGELVIRGEHRDEHAQEAGEANRRTL
MAB_4402|M.abscessus_ATCC_1997      GDDALVRLDLPGVDVGKDVTVEVERGTLVVSGERRDERAEQT---EGRTL
Mflv_1805|M.gilvum_PYR-GCK          DDHYVLTADLPGVDPG-SVDVDVDNGTLTISAHRTARSDESA----QWLS
MLBr_01795|M.leprae_Br4923          GEEFVVEFDLPGIKAD-SLDIDIERNVVTVRAERPG-VDPDR----EMLA
                                         :  ::**:.   .: : :  . :.: ..:      .         

Rv2031c|M.tuberculosis_H37Rv        SEFAYGSFVRTVSLPVGADEDDIKATYDKGILTVSVAVSEGK-PTEKHIQ
Mb2057c|M.bovis_AF2122/97           SEFAYGSFVRTVSLPVGADEDDIKATYDKGILTVSVAVSEGK-PTEKHIQ
MMAR_3484|M.marinum_M               SEFCYGSFIRTVPLPAGVTEDGIEASYDKGILTVSVPVAEAK-PAERRVR
MSMEG_3932|M.smegmatis_MC2_155      SEFAYGSFMRSVTLPPGADEDAIKAGYDKGILTISVPVTEPEAAAEKRVA
Mvan_1374|M.vanbaalenii_PYR-1       SEFSYGSFTRAVTLPAGADEDGIKASYDKGILSVSVPLKESE-APEKHIA
TH_1239|M.thermoresistible__bu      SEFNYGSFVRTVSLPASADEENITADYDKGILTVSVPLRETQ-PSPKRIE
MAV_4906|M.avium_104                REIRYGSFHRSFQLPGHVTDDDITASYDAGVLTVRVTGAY---AGNQAKR
MUL_1178|M.ulcerans_Agy99           REIRYGSFRRSFQLPEHVTSEAVSASYDAGVLTVRVQGAYRDPAASEPQR
MAB_4402|M.abscessus_ATCC_1997      REVRYGTFRRTFTLPTHVTGDAISASYDAGILTVKVAGAY---ANAAAQK
Mflv_1805|M.gilvum_PYR-GCK          SERFYGTYRRQLSLGDGIDTGAISATYENGVLTVTIPVAAKARPRKIAIN
MLBr_01795|M.leprae_Br4923          AERPRGVFNRQLVLGENLDTERILASYQEGVLKLSIPVAERAKPRKISVD
                                     *   * : * . *        : * *: *:*.: :       .      

Rv2031c|M.tuberculosis_H37Rv        IRSTN--------------
Mb2057c|M.bovis_AF2122/97           IRSTN--------------
MMAR_3484|M.marinum_M               VQSVN--------------
MSMEG_3932|M.smegmatis_MC2_155      VETVSP-------------
Mvan_1374|M.vanbaalenii_PYR-1       VEAAN--------------
TH_1239|M.thermoresistible__bu      VKAGT--------------
MAV_4906|M.avium_104                IAITK--------------
MUL_1178|M.ulcerans_Agy99           IAITK--------------
MAB_4402|M.abscessus_ATCC_1997      IEITT--------------
Mflv_1805|M.gilvum_PYR-GCK          HTKSQTSIEANTVDAE---
MLBr_01795|M.leprae_Br4923          RGNNGHQTINKTAHEIIDA