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MNGLGDVLAVARKARGLTQIELAELVGLTQPAINRYESGDRDPDQHIVAKLAEILGVTDDLLIHGNRFRG ALAVDAHMRRHKTTKASAWRQLEARLNLLRVHASFLFEEVAINSEQHVPAFDPEFTAAEDAARLVRAQWR MPMGPVVNLTRWMEAAGCLVFEEDFATQRIDGLSQWVDDYPVMLINANAAPDRKRLTLAHELGHLVLHST NPTENMETEATAFAAEFLMPESEIRPELRRLDLGKLLELKREWGVSMQALLARAYRMGLVSAEARTKLYK AMNARGWKTKEPGIESIVREKPSLPAHIGMTLRSRGFTDQQAAAIAGYANPADNPFRPEGGRLHAI
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2017 | - | - | 100% (346) | POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN |
| M. tuberculosis H37Rv | Rv2515c | - | 1e-09 | 23.70% (308) | hypothetical protein Rv2515c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2040 | - | 0.0 | 99.71% (346) | regulatory protein |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4876c | - | 2e-17 | 27.05% (329) | hypothetical protein MAB_4876c |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_0506 | - | 8e-17 | 33.52% (176) | DNA-binding protein, putative |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_2779 | - | 7e-11 | 36.07% (122) | PUTATIVE protein of unknown function DUF955 |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_5417 | - | 3e-14 | 34.59% (133) | hypothetical protein Mvan_5417 |
CLUSTAL 2.0.9 multiple sequence alignment
TH_2779|M.thermoresistible__bu --------------------------------------------------
Mvan_5417|M.vanbaalenii_PYR-1 --MTVEVFGARVRQARVLRQMTATAVMEHMGWRSPRQTRLEQAETATLDA
MAB_4876c|M.abscessus_ATCC_199 MTKTVEIFGLRVRQARLMRRLTAKHVMEAVGWSGARLSRLERSETAQVSE
MAV_0506|M.avium_104 MKTTVQIYGLRVNQARVMRAMTVTAVMEALGWKHSRLNRLEKSTTALVPV
Rv2017|M.tuberculosis_H37Rv ----MNGLGDVLAVARKARGLTQIELAELVGLTQPAINRYESGD-RDPDQ
Mb2040|M.bovis_AF2122/97 ----MNGLGDVLAVARKARGLTQIELAELVGLTQPAINRYESGD-RDPDQ
TH_2779|M.thermoresistible__bu --------------------------------------------------
Mvan_5417|M.vanbaalenii_PYR-1 LEFEALVALLRFPARFFTTAPVSR--VAARDLLFRAPKATTVTEKEYLAV
MAB_4876c|M.abscessus_ATCC_199 GELAALMDVLRVPALFFTSVPVCR--VEPDQLLFRAPKSTTETEKNRMAQ
MAV_0506|M.avium_104 EDFDRLVEVLRFPAKFFTTAPTSR--VHPSDLLFRAPRSITVSEREYLAQ
Rv2017|M.tuberculosis_H37Rv HIVAKLAEILGVTDDLLIHGNRFRGALAVDAHMRRHKTTKASAWRQLEAR
Mb2040|M.bovis_AF2122/97 HIVAKLAEILGVTDDLLIHGNRFRGALAVDAHMRRHKTTKASAWRQLEAR
TH_2779|M.thermoresistible__bu --------------------------------------------------
Mvan_5417|M.vanbaalenii_PYR-1 FANVVGDLVDQLNGVEKGPVVALEPLPVGTDVVTAAAKARAWLGREACEP
MAB_4876c|M.abscessus_ATCC_199 FIALSGDFLLEMNGRHKLPPVQISAAPDPDPVS-AALHARQCLGVDRDVP
MAV_0506|M.avium_104 FAALAGEFLDELDSRAQLPPVRLPVLPSHTPVAKAAEVVRQALGFDVDVP
Rv2017|M.tuberculosis_H37Rv LNLLRVHASFLFEEVAINSEQHVPAFDPEFTAAEDAARLVRAQWRMPMGP
Mb2040|M.bovis_AF2122/97 LNLLRVHASFLFEEVAINSEQHVPAFDPEFTAAEDAARLVRAQWRMPMGP
TH_2779|M.thermoresistible__bu --------------------------------------------------
Mvan_5417|M.vanbaalenii_PYR-1 IRYLTYDLEAAGVPVVLRTKHSRSTGRIDWDTQDEEPAGGLTEKHLGCSA
MAB_4876c|M.abscessus_ATCC_199 IGDLTHLFERGGIPVVMRYERFGGS-------APEDNSRGRLEKHLGCST
MAV_0506|M.avium_104 IEYLTHEVERSGVVIVVRRLLTSSSRRV----LGDEDSTGKLDKHLGYSV
Rv2017|M.tuberculosis_H37Rv VVNLTRWMEAAGCLVFEEDFA--------------------TQRIDGLSQ
Mb2040|M.bovis_AF2122/97 VVNLTRWMEAAGCLVFEEDFA--------------------TQRIDGLSQ
TH_2779|M.thermoresistible__bu ---------------MESWERTRWTVAHEIGHLVLHRY-GDISDEEEREA
Mvan_5417|M.vanbaalenii_PYR-1 RTGEFRQRPLVLMRSIDSWERSRWTVAHEIGHLVLHRH-GEVSDDQENEA
MAB_4876c|M.abscessus_ATCC_199 WVGEFRERPLIVLRELDSWERTRWTLAHELGHLILHTNVAELTDDHEDQA
MAV_0506|M.avium_104 RVGEFNTRPLIVVRQSNSWERTRWTLAHEVGHLSLHAS-GGVTEEREEQA
Rv2017|M.tuberculosis_H37Rv WVDDY---PVMLINANAAPDRKRLTLAHELGHLVLHST--NPTENMETEA
Mb2040|M.bovis_AF2122/97 WVDDY---PVMLINANAAPDRKRLTLAHELGHLVLHST--NPTENMETEA
: :*.* *:***:*** ** ::: * :*
TH_2779|M.thermoresistible__bu SRFASELLAPAEAIAAEIPDAPTLNDLIEVKLKWRISIGALIIHLRESKL
Mvan_5417|M.vanbaalenii_PYR-1 SRFASEFLAPAAAIAAEITDAPTLNHLMPVKLKWGISLGALIMHLRESKL
MAB_4876c|M.abscessus_ATCC_199 SRFASEFLAPFAAVSQSVKAAPSLLNLLPVKQKWGISVGALLRHFHDSGA
MAV_0506|M.avium_104 SAFASELLAPAGVLAEEVSRAPSLAELLPVKAKWGISLGALLRHLHVSGL
Rv2017|M.tuberculosis_H37Rv TAFAAEFLMPESEIRPELRRLD-LGKLLELKREWGVSMQALLARAYRMGL
Mb2040|M.bovis_AF2122/97 TAFAAEFLMPESEIRPELRRLD-LGKLLELKREWGVSMQALLERAYRMGL
: **:*:* * : .: * .*: :* :* :*: **: :
TH_2779|M.thermoresistible__bu IDDARALTLQRQLYTRINTDTGHTWGKTEPGWDTYKPERPRLLRRWMGVC
Mvan_5417|M.vanbaalenii_PYR-1 IDEHRAAMLQRQLYTRINSETGRTWGKTEPGWDARLPEQPRLLIKWVEAC
MAB_4876c|M.abscessus_ATCC_199 LDTERYDMLRTQLYTRINADTGFTWGRTEPGWDDRKPERPRLMSKWIEFA
MAV_0506|M.avium_104 LASDRFEALRRQLYTRVNAETDTTWGRVEPGWNDRDVERPLLISRWLDIA
Rv2017|M.tuberculosis_H37Rv VS----AEARTKLYKAMNARG---WKTKEPGIESIVREKP----------
Mb2040|M.bovis_AF2122/97 VS----AEARTKLYKAMNARG---WKTKEPGIESIVREKP----------
: : :**. :*: * *** : *:*
TH_2779|M.thermoresistible__bu YAGADSAEALAAHNLIYPTDLLADILAGQ--GDAPGRSRTEHARTADVGA
Mvan_5417|M.vanbaalenii_PYR-1 YG-ATSVEMLAALDLIFPADLLADILAGQRGASAPRPARVDVALAPVGGT
MAB_4876c|M.abscessus_ATCC_199 FG-VSSPEALMAHRVMWPLDMLQEFLVGQR-MAVPAT---GAPRPPSPRG
MAV_0506|M.avium_104 FS-ARSAAMLAPYELMWPQDVLEDFMAGQR-GATGTHTHGAEERVPALAG
Rv2017|M.tuberculosis_H37Rv -----------SLPAHIGMTLRSRGFTDQQAAAIAGYANPADNPFRPEGG
Mb2040|M.bovis_AF2122/97 -----------SLPAHIGMTLRSRGFTDQQAAAIAGYANPADNPFRPEGG
. : :..*
TH_2779|M.thermoresistible__bu GQGDIVVPLH----RAPRQA
Mvan_5417|M.vanbaalenii_PYR-1 DRGDTVVVAASERFRSRRQA
MAB_4876c|M.abscessus_ATCC_199 -SGGVADFAA----YRRRRA
MAV_0506|M.avium_104 RHDNVIVLSQ----RGNRRG
Rv2017|M.tuberculosis_H37Rv RLHAI---------------
Mb2040|M.bovis_AF2122/97 RLHAI---------------