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MTVEVFGARVRQARVLRQMTATAVMEHMGWRSPRQTRLEQAETATLDALEFEALVALLRFPARFFTTAPV SRVAARDLLFRAPKATTVTEKEYLAVFANVVGDLVDQLNGVEKGPVVALEPLPVGTDVVTAAAKARAWLG REACEPIRYLTYDLEAAGVPVVLRTKHSRSTGRIDWDTQDEEPAGGLTEKHLGCSARTGEFRQRPLVLMR SIDSWERSRWTVAHEIGHLVLHRHGEVSDDQENEASRFASEFLAPAAAIAAEITDAPTLNHLMPVKLKWG ISLGALIMHLRESKLIDEHRAAMLQRQLYTRINSETGRTWGKTEPGWDARLPEQPRLLIKWVEACYGATS VEMLAALDLIFPADLLADILAGQRGASAPRPARVDVALAPVGGTDRGDTVVVAASERFRSRRQA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5417 | - | - | 100% (414) | hypothetical protein Mvan_5417 |
| M. vanbaalenii PYR-1 | Mvan_0511 | - | 0.0 | 100.00% (414) | hypothetical protein Mvan_0511 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2040 | - | 3e-14 | 34.59% (133) | regulatory protein |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv2017 | - | 2e-14 | 34.59% (133) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0441 | - | 1e-166 | 70.77% (414) | hypothetical protein MAB_0441 |
| M. marinum M | MMAR_0024 | - | 9e-05 | 28.69% (122) | plasmid maintenance system antidote protein |
| M. avium 104 | MAV_0506 | - | 1e-106 | 48.63% (401) | DNA-binding protein, putative |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_2779 | - | 3e-69 | 68.06% (191) | PUTATIVE protein of unknown function DUF955 |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2040|M.bovis_AF2122/97 ----MNGLGDVLAVARKARGLTQIELAELVGLTQPAINRYESGD-RDPDQ
Rv2017|M.tuberculosis_H37Rv ----MNGLGDVLAVARKARGLTQIELAELVGLTQPAINRYESGD-RDPDQ
Mvan_5417|M.vanbaalenii_PYR-1 --MTVEVFGARVRQARVLRQMTATAVMEHMGWRSPRQTRLEQAETATLDA
MAB_0441|M.abscessus_ATCC_1997 -MATVEVFGARVRQARVLRRMSSTAVMEHMGWRSPRQTRLEQSETAELDT
TH_2779|M.thermoresistible__bu --------------------------------------------------
MAV_0506|M.avium_104 MKTTVQIYGLRVNQARVMRAMTVTAVMEALGWKHSRLNRLEKSTTALVPV
MMAR_0024|M.marinum_M ----MNATGLSPRWASPP-GETIAQAAADRGISHSELATRLGLAKQQLAE
Mb2040|M.bovis_AF2122/97 HIVAKLAEILGVTDDLLIHGNRFRGALAVDAHMRRHKTTKASAWRQLEAR
Rv2017|M.tuberculosis_H37Rv HIVAKLAEILGVTDDLLIHGNRFRGALAVDAHMRRHKTTKASAWRQLEAR
Mvan_5417|M.vanbaalenii_PYR-1 LEFEALVALLRFPARFFTTAPVSR-VAARDLLFRAPKATTVTEKEYLAVF
MAB_0441|M.abscessus_ATCC_1997 AEFSRLVALLRFPARFFTSAPISR-VSAQDLLFRAPKSTTVSEKEYLAMF
TH_2779|M.thermoresistible__bu --------------------------------------------------
MAV_0506|M.avium_104 EDFDRLVEVLRFPAKFFTTAPTSR-VHPSDLLFRAPRSITVSEREYLAQF
MMAR_0024|M.marinum_M LLVGSLPITLGLAETLSATVGASR-----------------------EFW
Mb2040|M.bovis_AF2122/97 LNLLRVHASFLFEEVAINSEQHVPAFDPEFTAAEDAARLVRAQWRMPMGP
Rv2017|M.tuberculosis_H37Rv LNLLRVHASFLFEEVAINSEQHVPAFDPEFTAAEDAARLVRAQWRMPMGP
Mvan_5417|M.vanbaalenii_PYR-1 ANVVGDLVDQLNGVEKG-PVVALEPLPVGTDVVTAAAKARAWLGREACEP
MAB_0441|M.abscessus_ATCC_1997 ANVAGDLLDELNKHTKL-PGVQLEPVPVGTDVVTAAAKARSWLALEPSAP
TH_2779|M.thermoresistible__bu --------------------------------------------------
MAV_0506|M.avium_104 AALAGEFLDELDSRAQL-PPVRLPVLPSHTPVAKAAEVVRQALGFDVDVP
MMAR_0024|M.marinum_M ISRDAQYHDDLR---RVEADQWAQQFPISQMVEFGWISQPADWHEQIDAC
Mb2040|M.bovis_AF2122/97 VVNLTRWMEAAGCLVFEEDFAT---------------------QRIDGLS
Rv2017|M.tuberculosis_H37Rv VVNLTRWMEAAGCLVFEEDFAT---------------------QRIDGLS
Mvan_5417|M.vanbaalenii_PYR-1 IRYLTYDLEAAGVPVVLRTKHSRSTGRIDWDTQ-DEEPAGGLTEKHLGCS
MAB_0441|M.abscessus_ATCC_1997 VRYLTYDLECAGVPVIMRSRHSRSSRYVNWDNEIDDEPAGLLTERHLGCS
TH_2779|M.thermoresistible__bu --------------------------------------------------
MAV_0506|M.avium_104 IEYLTHEVERSGVVIVVRRLLTSSSRRV-----LGDEDSTGKLDKHLGYS
MMAR_0024|M.marinum_M LEYFQVEEPAG-------------------------------WETRYGQA
Mb2040|M.bovis_AF2122/97 QWVDDY---PVMLINANAAPDRKRLTLAHELGHLVLHST-NPTENMETEA
Rv2017|M.tuberculosis_H37Rv QWVDDY---PVMLINANAAPDRKRLTLAHELGHLVLHST-NPTENMETEA
Mvan_5417|M.vanbaalenii_PYR-1 ARTGEFRQRPLVLMRSIDSWERSRWTVAHEIGHLVLHRHGEVSDDQENEA
MAB_0441|M.abscessus_ATCC_1997 ARTGEFRQRPLVLVRGMDSWERTRWTIAHEIGHLVLHRYGAVSDEEERAA
TH_2779|M.thermoresistible__bu ----------------MESWERTRWTVAHEIGHLVLHRYGDISDEEEREA
MAV_0506|M.avium_104 VRVGEFNTRPLIVVRQSNSWERTRWTLAHEVGHLSLHASGGVTEEREEQA
MMAR_0024|M.marinum_M LCTARYRKSPTFDVDAAATSAWFRACEAQAEGQFTSGFFDADRFAKMVAD
: * *: *::
Mb2040|M.bovis_AF2122/97 TAFAAEFLMPESEIRPELR-RLDLG-KLLELKREWGVSMQALLERAYRMG
Rv2017|M.tuberculosis_H37Rv TAFAAEFLMPESEIRPELR-RLDLG-KLLELKREWGVSMQALLARAYRMG
Mvan_5417|M.vanbaalenii_PYR-1 SRFASEFLAPAAAIAAEITDAPTLN-HLMPVKLKWGISLGALIMHLRESK
MAB_0441|M.abscessus_ATCC_1997 SRFASEFLAPAAVIADELPAAVTLN-SLIPLKLRWGISLGALIMHLRQSA
TH_2779|M.thermoresistible__bu SRFASELLAPAEAIAAEIPDAPTLN-DLIEVKLKWRISIGALIIHLRESK
MAV_0506|M.avium_104 SAFASELLAPAGVLAEEVSRAPSLA-ELLPVKAKWGISLGALLRHLHVSG
MMAR_0024|M.marinum_M LVSLTRIKDPARFIPQLTARCAEAGVVVVVVRPPKGCPVSGVARTYRGRP
:.: * : :: :: .: .:
Mb2040|M.bovis_AF2122/97 LVS----AEARTKLYKAMNARG---WKTKEPGIESIVREKPSLP------
Rv2017|M.tuberculosis_H37Rv LVS----AEARTKLYKAMNARG---WKTKEPGIESIVREKPSLP------
Mvan_5417|M.vanbaalenii_PYR-1 LIDEHRAAMLQRQLYTRINSETGRTWGKTEPGWDARLPEQPRLLIKWVEA
MAB_0441|M.abscessus_ATCC_1997 LIDQDRAETLQRQLYTRINTETGCTWGKTEPGWDARKPERPRLLLKWIEE
TH_2779|M.thermoresistible__bu LIDDARALTLQRQLYTRINTDTGHTWGKTEPGWDTYKPERPRLLRRWMGV
MAV_0506|M.avium_104 LLASDRFEALRRQLYTRVNAETDTTWGRVEPGWNDRDVERPLLISRWLDI
MMAR_0024|M.marinum_M LIQLSARNLSDDHFWFSFFHEAG--HIVLHPHEEMYIDNFDEGLNDDVEA
*: ::: . .* : :
Mb2040|M.bovis_AF2122/97 ------AHIGMTLRSRGFTDQQAAAIAGYANPADNPFRPEGGRLHAI---
Rv2017|M.tuberculosis_H37Rv ------AHIGMTLRSRGFTDQQAAAIAGYANPADNPFRPEGGRLHAI---
Mvan_5417|M.vanbaalenii_PYR-1 CYG-ATSVEMLAALDLIFPADLLADILAGQRGASAPRPARVDVALAPVGG
MAB_0441|M.abscessus_ATCC_1997 CFG-ASSAVELAVHDLIFPTDLLADFLTGQRGTPPKSAAQSARERDLVNA
TH_2779|M.thermoresistible__bu CYAGADSAEALAAHNLIYPTDLLADILAGQGDAPGRSRTEHAR-TADVGA
MAV_0506|M.avium_104 AFS-ARSAAMLAPYELMWPQDVLEDFMAGQRGATG-THTHGAEERVPALA
MMAR_0024|M.marinum_M EAN-AFAERQLFPAGVDVQGRLTSRAIVRAAQANGVSTGVVVGQLQYRGA
: : :
Mb2040|M.bovis_AF2122/97 -----------------------
Rv2017|M.tuberculosis_H37Rv -----------------------
Mvan_5417|M.vanbaalenii_PYR-1 TDRGDTVVVAASERFRSRRQA--
MAB_0441|M.abscessus_ATCC_1997 GARG---QVLKLDRARSCRQA--
TH_2779|M.thermoresistible__bu GQGD---IVVPLHRAP--RQA--
MAV_0506|M.avium_104 GRHDN--VIVLSQRGN--RRG--
MMAR_0024|M.marinum_M IRQNQFNTLKRRYVWDGPNLGMK