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DSPTNDGTCDAHPVTDEPFIDVRETHTAVVVLAGDRAFKAKKPVVTDFCDFRTAEQRERACIREFELNSR LAAQSYLGIAHLSDPSGGHAEPVVVMRRYRDKQRLASMVTAGLPVEGALDAIAEVLARFHQRAQRNRCID TQGEVGAVARRWHENLAELRHHADKVVSGDVIRRIEHMVDEFVSGREVLFAGRIKEGCIVDGHADLLADD IFLVDGEPALLDCLEFEDELRYLDRIDDAAFLAMDLEFLGRKDLGDYFLAGYAVRSGDTAPASLRDFYIA YRAVVRAKVECVRFSQGKPEAAADAVRHLIIATQHLQHATVRLALVGGNPGTGKSTLARGVAELVGAQVI STDDVRRRLRDCGVITGEPGVLDSGLYSRANVVAVYQEALRKARLLLGSGHSVILDGTWGDPQMRACARR LAADTHSAIVEFRCSATVDVMADRIVARAGGNSDATAEIAAALAARQADWDTGHRIDTAGPRERSVGQAY HIWRSAI*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2004c | - | - | 100% (498) | hypothetical protein Rv2004c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2027c | - | 0.0 | 100.00% (498) | hypothetical protein Mb2027c |
| M. gilvum PYR-GCK | Mflv_0263 | - | 1e-134 | 54.79% (480) | hypothetical protein Mflv_0263 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3902c | - | 1e-145 | 54.89% (481) | hypothetical protein MAB_3902c |
| M. marinum M | MMAR_3476 | - | 1e-173 | 65.34% (479) | hypothetical protein MMAR_3476 |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_3942 | - | 1e-142 | 56.51% (476) | hypothetical protein MSMEG_3942 |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_1384 | - | 1e-141 | 55.51% (472) | hypothetical protein Mvan_1384 |
CLUSTAL 2.0.9 multiple sequence alignment
Rv2004c|M.tuberculosis_H37Rv -MDSPTN-------DGTCDAHPVTDEPFIDVRETHTAVVVLAGDRAFKAK
Mb2027c|M.bovis_AF2122/97 -MDSPTN-------DGTCDAHPVTDEPFIDVRETHTAVVVLAGDRAFKAK
MMAR_3476|M.marinum_M ------------------------------MHETHTGVVVLVGERAYKAK
Mflv_0263|M.gilvum_PYR-GCK -MGTP-------------------GNLDAQIHETHTGLVVLLGERAYKAK
MSMEG_3942|M.smegmatis_MC2_155 MEDKPETA------VAQRDRVFAFGNLDAQIRETHTGLVALIGDLAYKAK
Mvan_1384|M.vanbaalenii_PYR-1 MSGGS---------------WLTTGNLGAEVHETHTGLVALVGDRAFKIK
MAB_3902c|M.abscessus_ATCC_199 MTGCPQLPPRNDEVMRSLRSTLSPTSVGAEIRETHTGIVILVGGMAYKIK
::****.:* * * *:* *
Rv2004c|M.tuberculosis_H37Rv KPVVTDFCDFRTAEQRERACIREFELNSRLAAQSYLGIAHLSDPSGGHAE
Mb2027c|M.bovis_AF2122/97 KPVVTDFCDFRTAEQRERACIREFELNSRLAAQSYLGIAHLSDPSGGHAE
MMAR_3476|M.marinum_M KPVLTDFLDFRTAEQRERACAREVELNSRLAPTSYLGVAHCTDPTGGPAE
Mflv_0263|M.gilvum_PYR-GCK KAVKTDFLDFSTVEQRARALHHEVTLNRRLAPQSYLGVGEFAMPGAQP-E
MSMEG_3942|M.smegmatis_MC2_155 KPVRTDFLDFTTAQQREAACLREVELNSRLAPNSYLGVAHLVGPGDRPDE
Mvan_1384|M.vanbaalenii_PYR-1 KPVVTDFLDFSTAQKRETACRREIELNRRLASSSYLGVGHFQPPSGDA-E
MAB_3902c|M.abscessus_ATCC_199 KPVITNFLDFSTPELRERACAREVALNSRISQDSYLGVSHLTDPDGGSGE
*.* *:* ** * : * * :*. ** *:: ****:.. * *
Rv2004c|M.tuberculosis_H37Rv PVVVMRRYRDKQRLASMVTAG---LPVEGALDAIAEVLARFHQRAQRNRC
Mb2027c|M.bovis_AF2122/97 PVVVMRRYRDKQRLASMVTAG---LPVEGALDAIAEVLARFHQRAQRNRC
MMAR_3476|M.marinum_M PLVVMRRYHDSDRLAYQISSGGSDESVRALLDTIATVLARFHEGAERSPT
Mflv_0263|M.gilvum_PYR-GCK PVIVMRRYPDSARLTSLVAQG---KPLTAELREIAGRLADFHRDARRGPD
MSMEG_3942|M.smegmatis_MC2_155 PVVVMRRYRDADRLSTLVTRG---AEVNDQLDVIAEILARFHRDAGRGAV
Mvan_1384|M.vanbaalenii_PYR-1 PVIVMRRYPDTERLAELVRSG---VPVETWLTAIADLLARFHSRAERGDA
MAB_3902c|M.abscessus_ATCC_199 PVVVMRRYPDAARLSAMAKSK---RVTKAHLDAIAEVLAGFHKRADRSPS
*::***** * **: * ** ** ** * *.
Rv2004c|M.tuberculosis_H37Rv IDTQGEVGAVARRWHENLAELRHHADKVVSGDVIRRIEHMVDEFVSGREV
Mb2027c|M.bovis_AF2122/97 IDTQGEVGAVARRWHENLAELRHHADKVVSGDVIRRIEHMVDEFVSGREV
MMAR_3476|M.marinum_M INTAGEPAAIGRRFGDNLAELHRYAGTSFPDESIGRIEDLVAAFISGRET
Mflv_0263|M.gilvum_PYR-GCK IDAQGRPEAVWERWAQNLTELGRHADVVFDRADLDEIHALAQRFLAGRSV
MSMEG_3942|M.smegmatis_MC2_155 IDDQARATSVWARWDENLTELARMSLVPPE--QLSEVRRLASQYLSGRAE
Mvan_1384|M.vanbaalenii_PYR-1 IDREATARVLSDRWQQNLTELRRHAGTVVDDGQIAEVERLASAYLAGREP
MAB_3902c|M.abscessus_ATCC_199 IDEAGSLDAIVDRWDDTLTALEKYAGTVLAADDVRLVRTLATQFISGRAV
*: . : *: :.*: * : : : :. :. :::**
Rv2004c|M.tuberculosis_H37Rv LFAGRIKEGCIVDGHADLLADDIFLVDGEPALLDCLEFEDELRYLDRIDD
Mb2027c|M.bovis_AF2122/97 LFAGRIKEGCIVDGHADLLADDIFLVDGEPALLDCLEFEDELRYLDRIDD
MMAR_3476|M.marinum_M LLAQRIAQGCIVDGHGDLLADDIFCAEGGPALLDCLEFDDRLRYVDRVDD
Mflv_0263|M.gilvum_PYR-GCK LMAQRIAQGRIVDGHADLLTDDIFCMPDGPAMLDCLEFDDLLRYVDGVDD
MSMEG_3942|M.smegmatis_MC2_155 LFAERIADGRIVDGHADLLADDIFCTPEGPAILDCLEFDDTLRYVDGVDD
Mvan_1384|M.vanbaalenii_PYR-1 LYQARIAAHRVVDGHGDLLSQDIFCTAEGPMLLDCLEFDDRLRYVDGIDD
MAB_3902c|M.abscessus_ATCC_199 LFAQRVADGRIIDGHGDLLASDIFCLPNGPVLLDCLEFDDRLRHVDGLDD
* *: ::***.***:.*** * :******:* **::* :**
Rv2004c|M.tuberculosis_H37Rv AAFLAMDLEFLGRKDLGDYFLAGYAVRSGDTAPASLRDFYIAYRAVVRAK
Mb2027c|M.bovis_AF2122/97 AAFLAMDLEFLGRKDLGDYFLAGYAVRSGDTAPASLRDFYIAYRAVVRAK
MMAR_3476|M.marinum_M AAFLAMDLEFLGRKDLGEYFLDRYLAHSGDVAPASLRDFYIAYRAVVRAK
Mflv_0263|M.gilvum_PYR-GCK AAFLAMDLEFHGRGNLGDEFLREYVARAADPAPRSLQNFYIAYRAVVRAK
MSMEG_3942|M.smegmatis_MC2_155 AAFLAMDLEFLGSPELSAFFVDRYRHHAHDTAPQSLMDFYVAYRAVVRAK
Mvan_1384|M.vanbaalenii_PYR-1 AGFLAMDLEFLGRRDLADFFLDEYCRRADDPAAHSLRHFCIAYRAVVRAK
MAB_3902c|M.abscessus_ATCC_199 AAFLAMDLEFLGRPDLGDYFMNRYVELSADTAPEPLRHFYIAYRALVRAK
*.******** * :*. *: * : * *. .* .* :****:****
Rv2004c|M.tuberculosis_H37Rv VECVRFSQGKPEAAADAVRHLIIATQHLQHATVRLALVGGNPGTGKSTLA
Mb2027c|M.bovis_AF2122/97 VECVRFSQGKPEAAADAVRHLIIATQHLQHATVRLALVGGNPGTGKSTLA
MMAR_3476|M.marinum_M TDCVRLSQGKPEAAADAARHLELATRHLETGAVRLALVGGNPGTGKSTLA
Mflv_0263|M.gilvum_PYR-GCK VDCVRVEQGHPEAADDARRHLHLAADRLRDGAVRLVIVGGGPGSGKTTVS
MSMEG_3942|M.smegmatis_MC2_155 VECIRVGQGRPEAATDACRHIDIALDRLRAATVQLVIVGGGPGTGKTTVS
Mvan_1384|M.vanbaalenii_PYR-1 VDCVRVDQGHAEAIPDAQRHLAIALAHLRSGRVQLVVVGGGPGTGKTTLA
MAB_3902c|M.abscessus_ATCC_199 VDCIRFTQGQRSAAGRAAKHVAMALSHLGAATVRLVLVGGGPGAGKSTLA
.:*:*. **: .* * :*: :* :* . *:*.:***.**:**:*::
Rv2004c|M.tuberculosis_H37Rv RGVAELVGAQVISTDDVRRRLRDCGVITGEPGVLDSGLYSRANVVAVYQE
Mb2027c|M.bovis_AF2122/97 RGVAELVGAQVISTDDVRRRLRDCGVITGEPGVLDSGLYSRANVVAVYQE
MMAR_3476|M.marinum_M RALAEQVGAQVISTDDVRKELRDRGDIHGESGVLDEGLYTRDNVTVVYDL
Mflv_0263|M.gilvum_PYR-GCK RALAEVLGAQVISTDDVRRELRDAGVISGAVGALDSGLYAPESVARVYDE
MSMEG_3942|M.smegmatis_MC2_155 RALAEELGAVVISTDDVRRYLQESGVIGGAAGELDTGLYAPKNVAAVYDE
Mvan_1384|M.vanbaalenii_PYR-1 RALAQCVDAQLISTDEVRRELVGSGVVHGRAGELNTGLYTPENLSAVYDE
MAB_3902c|M.abscessus_ATCC_199 RRISEDIGAQVISTDEVRQQLHRLGVISGGKGVLDAGLYSTENVGAVYDA
* ::: :.* :****:**: * * : * * *: ***: .: **:
Rv2004c|M.tuberculosis_H37Rv ALRKARLLLGSGHSVILDGTWGDPQMRACARRLAADTHSAIVEFRCSATV
Mb2027c|M.bovis_AF2122/97 ALRKARLLLGSGHSVILDGTWGDPQMRACARRLAADTHSAIVEFRCSATV
MMAR_3476|M.marinum_M VLSRARRCLQEGRSVILDGTWRDPQSRARAHHLGGQTHAALVELLCTLPV
Mflv_0263|M.gilvum_PYR-GCK VLRRAEAAVTGGCSVILDGTWRDEEETGRARRLADSTATPLIEFTCVLPV
MSMEG_3942|M.smegmatis_MC2_155 VLARARHALTHGRSVILDGTWRDVGRRQRAHLLASETAVPVVEFTCSLPV
Mvan_1384|M.vanbaalenii_PYR-1 VLSRARAWLGAGHSVIVDGTWRDAGHRQRAHAVAAQTYSSIVELRCTLPV
MAB_3902c|M.abscessus_ATCC_199 VLRRARLALAGGHTVILDGTWRSPRHRLRAHQLAYEAGAPMVEFLCLAPL
.* :*. : * :**:**** . *: :. .: .::*: * .:
Rv2004c|M.tuberculosis_H37Rv DVMADRIVARAGGNSDATAEIAAAL----AARQADWDTGHRIDTAGPRER
Mb2027c|M.bovis_AF2122/97 DVMADRIVARAGGNSDATAEIAAAL----AARQADWDTGHRIDTAGPRER
MMAR_3476|M.marinum_M DMAADRISTRAPGNSEVTAEIAATM----AAQHAGWDTALPMDTSRPIEF
Mflv_0263|M.gilvum_PYR-GCK EEAGARIRARTQTTSDATPQIAEAL----AGR-TGVAGRHPLDTGRPLAE
MSMEG_3942|M.smegmatis_MC2_155 VAAGERIASRSGTTSDATPEIADAL----AEQGAGIVHGHSIDTSRPLRE
Mvan_1384|M.vanbaalenii_PYR-1 AEAERRIAGRGATASDATPAMAAEL----SRWESDWPGAHPIDTAGPLAD
MAB_3902c|M.abscessus_ATCC_199 VTAQHRVAARHDGVSDATGDIAAALGAEFAGPDRGWGEAHVIDTRLPLDR
*: * *:.* :* : : . :** *
Rv2004c|M.tuberculosis_H37Rv SVGQAYHIWRSAI---------
Mb2027c|M.bovis_AF2122/97 SVGQAYHIWRSAI---------
MMAR_3476|M.marinum_M SLNEAHDAWCRAIYPE------
Mflv_0263|M.gilvum_PYR-GCK SVAEAQRICRKVISPFTRG---
MSMEG_3942|M.smegmatis_MC2_155 SVTEAQRVCCLAI---------
Mvan_1384|M.vanbaalenii_PYR-1 SVAAARQVCLDTV---------
MAB_3902c|M.abscessus_ATCC_199 STAEAEELCRQALYAPVPCHPR
* * .: