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M. tuberculosis H37Rv Rv1939 (-)

annotation: PROBABLE OXIDOREDUCTASE
coordinates: 2192094 - 2192609
length: 171

VSCTFDMVPETVDHLDEVGLRRVFGCFPCGVIAVCAMVDDQPVGMAASSFTSVSVDPPLVSICVQNCSTT
WPKLRDRPRLGVSVLAEGHDAACMSLSRKEGNRFAGVFWSELSSGGVVIAGAGAWLDCRPYAEIPAGDHL
IALLEICAVRADPETPPLVFHGSRFRRLESR
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv1939--100% (171)PROBABLE OXIDOREDUCTASE
M. tuberculosis H37RvRv0245-4e-3949.37% (158) oxidoreductase
M. tuberculosis H37RvRv3567c-5e-1829.94% (157) oxidoreductase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1974-1e-97100.00% (167) oxidoreductase
M. gilvum PYR-GCKMflv_0399-6e-4050.65% (154) flavin reductase domain-containing protein
M. leprae Br4923MLBr_02561-2e-3750.34% (149) putative oxidoreductase
M. abscessus ATCC 19977MAB_4430c-2e-4150.65% (154) putative oxidoreductase
M. marinum MMMAR_2867-1e-7780.36% (168) oxidoreducatse
M. avium 104MAV_4912-1e-3953.02% (149) NADH-FMN oxidoreductase
M. smegmatis MC2 155MSMEG_0415-9e-4050.00% (154) NADH-FMN oxidoreductase
M. thermoresistible (build 8)TH_4645-4e-4254.36% (149) PUTATIVE flavin reductase domain protein, FMN-binding
M. ulcerans Agy99MUL_2887-2e-7880.95% (168) oxidoreducatse
M. vanbaalenii PYR-1Mvan_4001-3e-6373.20% (153) flavin reductase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0399|M.gilvum_PYR-GCK          -------MSGSEPQR--------------ISLDPSSLREAFGHFPSGVIA
MSMEG_0415|M.smegmatis_MC2_155      -------MSATD-------------------LSPTSLREAFGHFPSGVIA
MLBr_02561|M.leprae_Br4923          -------MRAMN------------------SLTPSLLRDAFGHFPSGVVA
MAV_4912|M.avium_104                -------MNSNN------------------KLTASSLREAFGHFPSGVVA
MAB_4430c|M.abscessus_ATCC_199      -------MTSDT------------------TLDAATLREAFGHFPTGVVA
TH_4645|M.thermoresistible__bu      -------MAMAQEGSRTAVLGDGAGFIGGAELTPEVLRRSFAHYPSGVTA
Rv1939|M.tuberculosis_H37Rv         MSCTFDMVPETVD-----------------HLDEVGLRRVFGCFPCGVIA
Mb1974|M.bovis_AF2122/97            MSCTFDMVPETVD-----------------HLDEVGLRRVFGCFPCGVIA
MMAR_2867|M.marinum_M               MSCAFDMIPQTVD-----------------PLDGAALRYAFGCFPSGVIA
MUL_2887|M.ulcerans_Agy99           MSCTFDMIPQTVD-----------------PLDGAALRYAFGCFPSGVIA
Mvan_4001|M.vanbaalenii_PYR-1       -------MELRDC-----------------PADGTELRRAFGCFPSGVTA
                                           :                            **  *. :* ** *

Mflv_0399|M.gilvum_PYR-GCK          IAAEVDGTRVGLAASTFVPVSLDPPLVSFCVQNSSSTWPLLKDLPYLGIS
MSMEG_0415|M.smegmatis_MC2_155      IAAEVDGTRVGLAASTFVPVSLEPPLVAFCVQNSSTTWPKLKDLPSLGIS
MLBr_02561|M.leprae_Br4923          IAAEVEGVREGLAASTFVPVSLEPPLVSFCVQNVSTTWLKLKAVPMLGIS
MAV_4912|M.avium_104                IAAEVNGTLEGLAASTFVPVSLDPPLVSFCVQNTSTTWPKLKDRPMLGIS
MAB_4430c|M.abscessus_ATCC_199      IAAEIDGTRTGLAASTFVPVSLDPPLVAFCVQNSSTTWPNLRGAPRLGIS
TH_4645|M.thermoresistible__bu      ICALLDGEPVGMAASSFTSVSLDPPLVSVCMAHTSETWPKLRSAERLGVS
Rv1939|M.tuberculosis_H37Rv         VCAMVDDQPVGMAASSFTSVSVDPPLVSICVQNCSTTWPKLRDRPRLGVS
Mb1974|M.bovis_AF2122/97            VCAMVDDQPVGMAASSFTSVSVDPPLVSICVQNCSTTWPKLRDRPRLGVS
MMAR_2867|M.marinum_M               VCAMVGDAPVGMAASSFTSVSIDPPLVSICVQNTSTTWPKLRNRPRLGVS
MUL_2887|M.ulcerans_Agy99           VCAMVGDAPVGMAASSFTSVSIDPPLVSICVQNTSTTWPKLRNRPRLGVS
Mvan_4001|M.vanbaalenii_PYR-1       VCAIIDGEPVGMAASSFTPVSIDPPLASICVQNTSTTWPRLRNQPRLGLS
                                    :.* : .   *:***:*..**::***.:.*: : * **  *:    **:*

Mflv_0399|M.gilvum_PYR-GCK          VLGEAHDEAARTLAAKTGDRFAGLETASSERGAVFVHGTSVWLETSIDQL
MSMEG_0415|M.smegmatis_MC2_155      VLGEAHDTAARTLAAKTGDRFAGLETESRDSGAVFIHGTAVWLESAIEQL
MLBr_02561|M.leprae_Br4923          VLGEVHDEVACTLATKHGDRFAGLETVSNDTGAVFIKGTSLWLESAIKQL
MAV_4912|M.avium_104                VLGEEHDEAARTLAAKTGDRFAGLETVSRPTGAVFIKGTALWLESAVEQL
MAB_4430c|M.abscessus_ATCC_199      VLGESHDEAARTLAAKTGDRFAGLDTSTTETGAVFIGGTTAWIETSVESE
TH_4645|M.thermoresistible__bu      VLSHHHGAVARALAAKTGDRFASVDWVADSQGSVFIGEATLWLDCTLSDQ
Rv1939|M.tuberculosis_H37Rv         VLAEGHDAACMSLSRKEGNRFAGVFWSELSSGGVVIAGAGAWLDCRPYAE
Mb1974|M.bovis_AF2122/97            VLAEGHDAACMSLSRKEGNRFAGVFWSELSSGGVVIAGAGAWLDCRPYAE
MMAR_2867|M.marinum_M               VLAEGHDEACISLSRKEGDRFAGVFHSELPGGGVVVLGASAWLECRLHSE
MUL_2887|M.ulcerans_Agy99           VLAEGHDEACISLSRKEGDRFAGVFHSELPGGGVVVLGASAWLECRLHSE
Mvan_4001|M.vanbaalenii_PYR-1       VLAEDHTAAAISLSRKVGDRFAGVSWAELPSGGVFVDGASAWWDCRVYAE
                                    **.. *  .. :*: * *:***.:       *.*.:  :  * :      

Mflv_0399|M.gilvum_PYR-GCK          VPAGDHTIVVLRVADITVHPDIAPIVFHRSVFRRLGA-------------
MSMEG_0415|M.smegmatis_MC2_155      VPAGDHTIVVLRVSDIVVNDDVAPIVFHRSSFRKLGA-------------
MLBr_02561|M.leprae_Br4923          IPAGDHTIVVLRVSQVTVDPDVAPIVFHRSMFRRLGF-------------
MAV_4912|M.avium_104                IPAGDHTIVVLRVNEVTVDANVAPIVFHRSGFRRLGA-------------
MAB_4430c|M.abscessus_ATCC_199      VPAGDHAIVILNIHGLTVHSSVAPIVFHRSKFRKLLG-------------
TH_4645|M.thermoresistible__bu      VRAGDHDIVILNVERVASNPDIAPIVFHGSTFRALA--------------
Rv1939|M.tuberculosis_H37Rv         IPAGDHLIALLEICAVRADPETPPLVFHGSRFRRLESR------------
Mb1974|M.bovis_AF2122/97            IPAGDHLIALLEICAVRADPETPPLVFHGSRFRRWSLDEDDRCAGTSCDH
MMAR_2867|M.marinum_M               VPAGDHTIALLEICSLGADPETPPLVFHGSRFRRLAAHPATEPG------
MUL_2887|M.ulcerans_Agy99           VPAGDHTIALLEICSLGADPETPPLVFHGSRFRRLAAHPATEPG------
Mvan_4001|M.vanbaalenii_PYR-1       VAAGDHTIVLLEICALGAAPSTPPLVFHGSRFRRLAMVMEERNEDH----
                                    : **** *.:*.:  :    . .*:*** * **                 

Mflv_0399|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_0415|M.smegmatis_MC2_155      --------------------------------------------------
MLBr_02561|M.leprae_Br4923          --------------------------------------------------
MAV_4912|M.avium_104                --------------------------------------------------
MAB_4430c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4645|M.thermoresistible__bu      --------------------------------------------------
Rv1939|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1974|M.bovis_AF2122/97            GDGGRSRRGPDRRPQWRWLSRLRRPGRDAAAGCLCGPAHLGLFARRAAGR
MMAR_2867|M.marinum_M               --------------------------------------------------
MUL_2887|M.ulcerans_Agy99           --------------------------------------------------
Mvan_4001|M.vanbaalenii_PYR-1       --------------------------------------------------
                                                                                      

Mflv_0399|M.gilvum_PYR-GCK          -----------
MSMEG_0415|M.smegmatis_MC2_155      -----------
MLBr_02561|M.leprae_Br4923          -----------
MAV_4912|M.avium_104                -----------
MAB_4430c|M.abscessus_ATCC_199      -----------
TH_4645|M.thermoresistible__bu      -----------
Rv1939|M.tuberculosis_H37Rv         -----------
Mb1974|M.bovis_AF2122/97            RMRATAPAAHV
MMAR_2867|M.marinum_M               -----------
MUL_2887|M.ulcerans_Agy99           -----------
Mvan_4001|M.vanbaalenii_PYR-1       -----------