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M. bovis AF2122 / 97 Mb1974 (-)

annotation: oxidoreductase
coordinates: 2183729 - 2184463
length: 244

VSCTFDMVPETVDHLDEVGLRRVFGCFPCGVIAVCAMVDDQPVGMAASSFTSVSVDPPLVSICVQNCSTT
WPKLRDRPRLGVSVLAEGHDAACMSLSRKEGNRFAGVFWSELSSGGVVIAGAGAWLDCRPYAEIPAGDHL
IALLEICAVRADPETPPLVFHGSRFRRWSLDEDDRCAGTSCDHGDGGRSRRGPDRRPQWRWLSRLRRPGR
DAAAGCLCGPAHLGLFARRAAGRRMRATAPAAHV
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1974--100% (244)oxidoreductase
M. bovis AF2122 / 97Mb0251-2e-3849.04% (157) putative oxidoreductase
M. bovis AF2122 / 97Mb3598c-1e-1732.41% (145) oxidoreductase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_0399-3e-3950.33% (153) flavin reductase domain-containing protein
M. tuberculosis H37RvRv1939-2e-97100.00% (167) oxidoreductase
M. leprae Br4923MLBr_02561-1e-3650.00% (148) putative oxidoreductase
M. abscessus ATCC 19977MAB_4430c-8e-4150.33% (153) putative oxidoreductase
M. marinum MMMAR_2867-6e-7780.24% (167) oxidoreducatse
M. avium 104MAV_4912-6e-3952.70% (148) NADH-FMN oxidoreductase
M. smegmatis MC2 155MSMEG_0415-5e-3949.67% (153) NADH-FMN oxidoreductase
M. thermoresistible (build 8)TH_4645-1e-4154.42% (147) PUTATIVE flavin reductase domain protein, FMN-binding
M. ulcerans Agy99MUL_2887-1e-7780.84% (167) oxidoreducatse
M. vanbaalenii PYR-1Mvan_4001-3e-6370.00% (160) flavin reductase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0399|M.gilvum_PYR-GCK          -------MSGSEPQR--------------ISLDPSSLREAFGHFPSGVIA
MSMEG_0415|M.smegmatis_MC2_155      -------MSATD-------------------LSPTSLREAFGHFPSGVIA
MLBr_02561|M.leprae_Br4923          -------MRAMN------------------SLTPSLLRDAFGHFPSGVVA
MAV_4912|M.avium_104                -------MNSNN------------------KLTASSLREAFGHFPSGVVA
MAB_4430c|M.abscessus_ATCC_199      -------MTSDT------------------TLDAATLREAFGHFPTGVVA
TH_4645|M.thermoresistible__bu      -------MAMAQEGSRTAVLGDGAGFIGGAELTPEVLRRSFAHYPSGVTA
Mb1974|M.bovis_AF2122/97            MSCTFDMVPETVD-----------------HLDEVGLRRVFGCFPCGVIA
Rv1939|M.tuberculosis_H37Rv         MSCTFDMVPETVD-----------------HLDEVGLRRVFGCFPCGVIA
MMAR_2867|M.marinum_M               MSCAFDMIPQTVD-----------------PLDGAALRYAFGCFPSGVIA
MUL_2887|M.ulcerans_Agy99           MSCTFDMIPQTVD-----------------PLDGAALRYAFGCFPSGVIA
Mvan_4001|M.vanbaalenii_PYR-1       -------MELRDC-----------------PADGTELRRAFGCFPSGVTA
                                           :                            **  *. :* ** *

Mflv_0399|M.gilvum_PYR-GCK          IAAEVDGTRVGLAASTFVPVSLDPPLVSFCVQNSSSTWPLLKDLPYLGIS
MSMEG_0415|M.smegmatis_MC2_155      IAAEVDGTRVGLAASTFVPVSLEPPLVAFCVQNSSTTWPKLKDLPSLGIS
MLBr_02561|M.leprae_Br4923          IAAEVEGVREGLAASTFVPVSLEPPLVSFCVQNVSTTWLKLKAVPMLGIS
MAV_4912|M.avium_104                IAAEVNGTLEGLAASTFVPVSLDPPLVSFCVQNTSTTWPKLKDRPMLGIS
MAB_4430c|M.abscessus_ATCC_199      IAAEIDGTRTGLAASTFVPVSLDPPLVAFCVQNSSTTWPNLRGAPRLGIS
TH_4645|M.thermoresistible__bu      ICALLDGEPVGMAASSFTSVSLDPPLVSVCMAHTSETWPKLRSAERLGVS
Mb1974|M.bovis_AF2122/97            VCAMVDDQPVGMAASSFTSVSVDPPLVSICVQNCSTTWPKLRDRPRLGVS
Rv1939|M.tuberculosis_H37Rv         VCAMVDDQPVGMAASSFTSVSVDPPLVSICVQNCSTTWPKLRDRPRLGVS
MMAR_2867|M.marinum_M               VCAMVGDAPVGMAASSFTSVSIDPPLVSICVQNTSTTWPKLRNRPRLGVS
MUL_2887|M.ulcerans_Agy99           VCAMVGDAPVGMAASSFTSVSIDPPLVSICVQNTSTTWPKLRNRPRLGVS
Mvan_4001|M.vanbaalenii_PYR-1       VCAIIDGEPVGMAASSFTPVSIDPPLASICVQNTSTTWPRLRNQPRLGLS
                                    :.* : .   *:***:*..**::***.:.*: : * **  *:    **:*

Mflv_0399|M.gilvum_PYR-GCK          VLGEAHDEAARTLAAKTGDRFAGLETASSERGAVFVHGTSVWLETSIDQL
MSMEG_0415|M.smegmatis_MC2_155      VLGEAHDTAARTLAAKTGDRFAGLETESRDSGAVFIHGTAVWLESAIEQL
MLBr_02561|M.leprae_Br4923          VLGEVHDEVACTLATKHGDRFAGLETVSNDTGAVFIKGTSLWLESAIKQL
MAV_4912|M.avium_104                VLGEEHDEAARTLAAKTGDRFAGLETVSRPTGAVFIKGTALWLESAVEQL
MAB_4430c|M.abscessus_ATCC_199      VLGESHDEAARTLAAKTGDRFAGLDTSTTETGAVFIGGTTAWIETSVESE
TH_4645|M.thermoresistible__bu      VLSHHHGAVARALAAKTGDRFASVDWVADSQGSVFIGEATLWLDCTLSDQ
Mb1974|M.bovis_AF2122/97            VLAEGHDAACMSLSRKEGNRFAGVFWSELSSGGVVIAGAGAWLDCRPYAE
Rv1939|M.tuberculosis_H37Rv         VLAEGHDAACMSLSRKEGNRFAGVFWSELSSGGVVIAGAGAWLDCRPYAE
MMAR_2867|M.marinum_M               VLAEGHDEACISLSRKEGDRFAGVFHSELPGGGVVVLGASAWLECRLHSE
MUL_2887|M.ulcerans_Agy99           VLAEGHDEACISLSRKEGDRFAGVFHSELPGGGVVVLGASAWLECRLHSE
Mvan_4001|M.vanbaalenii_PYR-1       VLAEDHTAAAISLSRKVGDRFAGVSWAELPSGGVFVDGASAWWDCRVYAE
                                    **.. *  .. :*: * *:***.:       *.*.:  :  * :      

Mflv_0399|M.gilvum_PYR-GCK          VPAGDHTIVVLRVADITVHPDIAPIVFHRSVFRRLGA-------------
MSMEG_0415|M.smegmatis_MC2_155      VPAGDHTIVVLRVSDIVVNDDVAPIVFHRSSFRKLGA-------------
MLBr_02561|M.leprae_Br4923          IPAGDHTIVVLRVSQVTVDPDVAPIVFHRSMFRRLGF-------------
MAV_4912|M.avium_104                IPAGDHTIVVLRVNEVTVDANVAPIVFHRSGFRRLGA-------------
MAB_4430c|M.abscessus_ATCC_199      VPAGDHAIVILNIHGLTVHSSVAPIVFHRSKFRKLLG-------------
TH_4645|M.thermoresistible__bu      VRAGDHDIVILNVERVASNPDIAPIVFHGSTFRALA--------------
Mb1974|M.bovis_AF2122/97            IPAGDHLIALLEICAVRADPETPPLVFHGSRFRRWSLDEDDRCAGTSCDH
Rv1939|M.tuberculosis_H37Rv         IPAGDHLIALLEICAVRADPETPPLVFHGSRFRRLESR------------
MMAR_2867|M.marinum_M               VPAGDHTIALLEICSLGADPETPPLVFHGSRFRRLAAHPATEPG------
MUL_2887|M.ulcerans_Agy99           VPAGDHTIALLEICSLGADPETPPLVFHGSRFRRLAAHPATEPG------
Mvan_4001|M.vanbaalenii_PYR-1       VAAGDHTIVLLEICALGAAPSTPPLVFHGSRFRRLAMVMEERNEDH----
                                    : **** *.:*.:  :    . .*:*** * **                 

Mflv_0399|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_0415|M.smegmatis_MC2_155      --------------------------------------------------
MLBr_02561|M.leprae_Br4923          --------------------------------------------------
MAV_4912|M.avium_104                --------------------------------------------------
MAB_4430c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4645|M.thermoresistible__bu      --------------------------------------------------
Mb1974|M.bovis_AF2122/97            GDGGRSRRGPDRRPQWRWLSRLRRPGRDAAAGCLCGPAHLGLFARRAAGR
Rv1939|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_2867|M.marinum_M               --------------------------------------------------
MUL_2887|M.ulcerans_Agy99           --------------------------------------------------
Mvan_4001|M.vanbaalenii_PYR-1       --------------------------------------------------
                                                                                      

Mflv_0399|M.gilvum_PYR-GCK          -----------
MSMEG_0415|M.smegmatis_MC2_155      -----------
MLBr_02561|M.leprae_Br4923          -----------
MAV_4912|M.avium_104                -----------
MAB_4430c|M.abscessus_ATCC_199      -----------
TH_4645|M.thermoresistible__bu      -----------
Mb1974|M.bovis_AF2122/97            RMRATAPAAHV
Rv1939|M.tuberculosis_H37Rv         -----------
MMAR_2867|M.marinum_M               -----------
MUL_2887|M.ulcerans_Agy99           -----------
Mvan_4001|M.vanbaalenii_PYR-1       -----------