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M. tuberculosis H37Rv Rv1909c (furA)

annotation: FERRIC UPTAKE REGULATION PROTEIN FURA (FUR)
coordinates: 2156149 - 2156601
length: 150

SSVSSIPDYAEQLRTADLRVTRPRVAVLEAVNAHPHADTETIFGAVRFALPDVSRQAVYDVLHALTAAGL
VRKIQPSGSVARYESRVGDNHHHIVCRSCGVIADVDCAVGEAPCLTASDHNGFLLDEAEVIYWGLCPDCS
ISDTSRSHP*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv1909cfurA-100% (150)FERRIC UPTAKE REGULATION PROTEIN FURA (FUR)
M. tuberculosis H37RvRv2359furB8e-0826.92% (130) ferric uptake regulation protein FURB

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1944cfurA2e-85100.00% (150) ferric uptake regulation protein furA (fur)
M. gilvum PYR-GCKMflv_3452-1e-5875.74% (136) ferric uptake regulator family protein
M. leprae Br4923MLBr_00824furB4e-0827.56% (127) putative ferric uptake regulatory protein
M. abscessus ATCC 19977MAB_2471c-7e-6581.16% (138) ferric uptake regulation protein FurA
M. marinum MMMAR_2915furA2e-5776.09% (138) ferric uptake regulation protein FurA
M. avium 104MAV_2752-4e-5983.72% (129) transcriptional regulator, Fur family protein
M. smegmatis MC2 155MSMEG_6383-1e-5969.93% (153) transcription regulator FurA
M. thermoresistible (build 8)TH_0864furA4e-5076.27% (118) FERRIC UPTAKE REGULATION PROTEIN FURA (FUR)
M. ulcerans Agy99MUL_2189furA5e-5876.81% (138) ferric uptake regulation protein FurA
M. vanbaalenii PYR-1Mvan_2983-1e-6480.00% (145) ferric uptake regulator family protein

CLUSTAL 2.0.9 multiple sequence alignment


Rv1909c|M.tuberculosis_H37Rv        MSSVSSIPDYAEQLRTADLRVTRPRVAVLEAVN-AHPHADTETIFGAVRF
Mb1944c|M.bovis_AF2122/97           MSSVSSIPDYAEQLRTADLRVTRPRVAVLEAVN-AHPHADTETIFGAVRF
Mvan_2983|M.vanbaalenii_PYR-1       MTS-----DYAELLRGADLRVTRPRIAVLEAVE-AHPHADTDTIFGAVRT
MAB_2471c|M.abscessus_ATCC_199      MAFTS--DEYAALLRTADLRVTRPRVAVLEAVE-ANPHADTETVFGVVRT
MMAR_2915|M.marinum_M               ---------------MADLRVTRPRLAVLEAMG-DHPHADTETIYSAVRE
MUL_2189|M.ulcerans_Agy99           ---------------MADLRVTRPRLAVLEAVG-DHPHADTETIYSAVRE
MAV_2752|M.avium_104                ---------------MADLRVTRPRVAVLEVVD-ANPHADTETIFSAVRM
TH_0864|M.thermoresistible__bu      ---------------------------VLEAVH-DHPHADTESIYLAVRA
Mflv_3452|M.gilvum_PYR-GCK          ---MTDERDFSDVLRSAALRVTRPRMAVLSAVG-QHPHADTEVIIRAARQ
MSMEG_6383|M.smegmatis_MC2_155      ---MTHTTDFEQLLRSAGMRVTRPRIAVLRSVY-AHPHADTDTVIRAVRE
MLBr_00824|M.leprae_Br4923          ------------MMTGASVRSTRQRAAISTLLETVDDFRSAQELHNELRR
                                                               :   :   . . .:: :    * 

Rv1909c|M.tuberculosis_H37Rv        ALPDVSRQAVYDVLHALTAAGLVRKIQPSGSVARYESRVGDNHHHIVCRS
Mb1944c|M.bovis_AF2122/97           ALPDVSRQAVYDVLHALTAAGLVRKIQPSGSVARYESRVGDNHHHIVCRS
Mvan_2983|M.vanbaalenii_PYR-1       ALPEVSRQAVYDVLAALTGAGLVRKIQPSGSVARYETRVGDNHHHVVCRS
MAB_2471c|M.abscessus_ATCC_199      GLPEVSRQAVYDVLAALTSAGLIRKIQPSGSVARYESRVGDNHHHVVCRS
MMAR_2915|M.marinum_M               ILPDVSRQAVYDVLGALTSVGLVRRIQPSGSVARYESRVGDNHHHVVCRS
MUL_2189|M.ulcerans_Agy99           ILPDVSRQAVYDVLGALTSVGLVRRIQPSGSVARYESRVGDNHHHVVCRS
MAV_2752|M.avium_104                ALPDVSRQAVYDVLNALTAVGLVRRIQPLGMVARYESRVGDNHHHVVCRS
TH_0864|M.thermoresistible__bu      KLPAVSRQAVYDVLHALTATGLARRIQPPGSVARYEARVGDNHHHLVCRS
Mflv_3452|M.gilvum_PYR-GCK          ELPDISRQTVYDALNALTATGLVRRIQPAGSLARYESRVGDNHHHIVCRS
MSMEG_6383|M.smegmatis_MC2_155      ALPEVSHQAVYDSLHALAAARLVRRIQPSGSVARYESRVGDNHHHVVCRA
MLBr_00824|M.leprae_Br4923          RGNNISLTTVYRTLQSMAEAGMVDTLRTNTGESVYRRCSRQHHHHLVCRG
                                        :*  :**  * ::: . :   ::.    : *.    ::***:***.

Rv1909c|M.tuberculosis_H37Rv        CGVIADVDCAVGEAPCLTASDHNG----FLLDEAEVIYWGLCPDCSISD-
Mb1944c|M.bovis_AF2122/97           CGVIADVDCAVGEAPCLTASDHNG----FLLDEAEVIYWGLCPDCSISD-
Mvan_2983|M.vanbaalenii_PYR-1       CGVITDVDCAVGEAPCLVPSDPDGSLDGFVVDEAEVVYWGLCPGCLAAE-
MAB_2471c|M.abscessus_ATCC_199      CGAIADVDCAVGAAPCLTPSDYNG----FILEEAEVIYWGLCPDCASTEA
MMAR_2915|M.marinum_M               CGAIADIDCAVGEAPCLAPSDDSNVLDGFVVDEAEVIFWGMCPDCSTAM-
MUL_2189|M.ulcerans_Agy99           CGAIADIDCAVGEAPCLAPSDDSNVLDGFVVDEAEVIFWGMCPDCSTAM-
MAV_2752|M.avium_104                CGTIADVDCAVGEAPCLTPSDDDNVLDGFVLDEAEVIYWGLCADCSTAG-
TH_0864|M.thermoresistible__bu      CGSVADIDCAVGAAPCLTPADPGGVLDGFLLDEAEVIYWGVCPDCARTEP
Mflv_3452|M.gilvum_PYR-GCK          CGVIADVDCAVGDTPCLTASDDLG----FEVDEAEVIYWGLCPECSTTD-
MSMEG_6383|M.smegmatis_MC2_155      CGDIADVDCAVGEAPCLTGSDHHG----YAIDEAEVIYWGTCPACAQDPD
MLBr_00824|M.leprae_Br4923          CGSTIEVGDHEVEAWAAEVAAKHG----FSDVSHTIEIFGTCSECRS---
                                    **   ::.     : .   :   .    :   .  :  :* *. *     

Rv1909c|M.tuberculosis_H37Rv        -----TSRSHP
Mb1944c|M.bovis_AF2122/97           -----TSRSHP
Mvan_2983|M.vanbaalenii_PYR-1       -----ISRSHQ
MAB_2471c|M.abscessus_ATCC_199      --APRISGSHT
MMAR_2915|M.marinum_M               ------PRSQP
MUL_2189|M.ulcerans_Agy99           ------PRSQP
MAV_2752|M.avium_104                ------S----
TH_0864|M.thermoresistible__bu      --I--------
Mflv_3452|M.gilvum_PYR-GCK          ------APAH-
MSMEG_6383|M.smegmatis_MC2_155      RAKARTSRSHP
MLBr_00824|M.leprae_Br4923          -----------