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M. tuberculosis H37Rv Rv1712 (cmk)

annotation: cytidylate kinase
coordinates: 1939599 - 1940291
length: 230

VSRLSAAVVAIDGPAGTGKSSVSRRLARELGARFLDTGAMYRIVTLAVLRAGADPSDIAAVETIASTVQM
SLGYDPDGDSCYLAGEDVSVEIRGDAVTRAVSAVSSVPAVRTRLVELQRTMAEGPGSIVVEGRDIGTVVF
PDAPVKIFLTASAETRARRRNAQNVAAGLADDYDGVLADVRRRDHLDSTRAVSPLQAAGDAVIVDTSDMT
EAEVVAHLLELVTRRSEAVR
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv1712cmk-100% (230)cytidylate kinase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1739cmk1e-123100.00% (230) cytidylate kinase
M. gilvum PYR-GCKMflv_3494cmk2e-8068.61% (223) cytidylate kinase
M. leprae Br4923MLBr_01371cmk7e-8574.77% (222) cytidylate kinase
M. abscessus ATCC 19977MAB_2371-1e-7868.16% (223) cytidylate kinase (Cmk)
M. marinum MMMAR_2527cmk2e-9378.92% (223) cytidylate kinase, Cmk
M. avium 104MAV_3064cmk9e-9378.48% (223) cytidylate kinase
M. smegmatis MC2 155MSMEG_3739cmk3e-8673.99% (223) cytidylate kinase
M. thermoresistible (build 8)TH_0201cmk6e-8573.54% (223) Probable Cytidylate kinase cmk (CMP kinase) (Cytidine
M. ulcerans Agy99MUL_3233cmk8e-9378.03% (223) cytidylate kinase
M. vanbaalenii PYR-1Mvan_3275cmk9e-8773.09% (223) cytidylate kinase

CLUSTAL 2.0.9 multiple sequence alignment


Rv1712|M.tuberculosis_H37Rv         ----------------------MSRLSAAVVAIDGPAGTGKSSVSRRLAR
Mb1739|M.bovis_AF2122/97            ----------------------MSRLSAAVVAIDGPAGTGKSSVSRRLAR
MMAR_2527|M.marinum_M               MSVGTSGTSVVSAGTSGTSGTNEPAPVGLVVAIDGPAGTGKSSVSRGLAR
MUL_3233|M.ulcerans_Agy99           ----------MSAGTSGTSGTNEPAPVGLVVAIDGPAGTGKSSVSRGLAR
MLBr_01371|M.leprae_Br4923          -------------------------MTDIVVAIDGPAGTGKSSVSRGLAR
MAV_3064|M.avium_104                ------------------------MSADVVVAIDGPAGTGKSSVSKGLAR
TH_0201|M.thermoresistible__bu      ----------------------------LVVAVDGPAGTGKSSVSKGLAR
Mflv_3494|M.gilvum_PYR-GCK          ------------------------MSRSLVIAIDGPAGTGKSSVAKGLAR
Mvan_3275|M.vanbaalenii_PYR-1       ------------------------MSRSLVIAIDGPAGTGKSSVARGLAV
MAB_2371|M.abscessus_ATCC_1997      -----------------------------MVAVDGPSGTGKSSVAKELAR
MSMEG_3739|M.smegmatis_MC2_155      ------------------------MSGSLVVAVDGPAGTGKSSVSRGLAR
                                                                 ::*:***:*******:: ** 

Rv1712|M.tuberculosis_H37Rv         ELGARFLDTGAMYRIVTLAVLRAGADPSDIAAVETIASTVQMSLGYDPDG
Mb1739|M.bovis_AF2122/97            ELGARFLDTGAMYRIVTLAVLRAGADPSDIAAVETIASTVQMSLGYDPDG
MMAR_2527|M.marinum_M               GLGSRFLDTGAMYRMVTLAVLRAGIDPADEQAVANCAASAQLSVGYDPDA
MUL_3233|M.ulcerans_Agy99           GLGSRFLDTGAMYRMVTLSVLRAGIDPADEQAVADCAASAQLSVGYDPDA
MLBr_01371|M.leprae_Br4923          ELGARYLDTGAMYRMMTLAVLRAGIDPADAAAIGESVWKVQMLSDH----
MAV_3064|M.avium_104                ALGARYLDTGGMYRMVTLAVLRAGIDPADADAVGRAAQAVRMSVDYHPDG
TH_0201|M.thermoresistible__bu      ALGARYLDTGAMYRIVTLAVLRAGVDPGNAEAVAEIADTVQLDVGQSPDD
Mflv_3494|M.gilvum_PYR-GCK          SLNASYLDTGAMYRIVTLNALRAGVDLDDAAAIAAATDEVDLAVGYDPDE
Mvan_3275|M.vanbaalenii_PYR-1       AMGARYLDTGAMYRIVTLGVLRAGVDPADAAAVAAVAAEVELAVGHDPGE
MAB_2371|M.abscessus_ATCC_1997      QLGASYLDTGAMYRIVTLWVLRAGVDLTDPAAIAAATDQVPMSVSSDPDA
MSMEG_3739|M.smegmatis_MC2_155      ALGARYLDTGAMYRIATLAVLRAGADLTDPAAIEKAAADAEIGVGSDPDV
                                     :.: :****.***: ** .**** *  :  *:   .  . :  .     

Rv1712|M.tuberculosis_H37Rv         DSCYLAGEDVSVEIRGDAVTRAVSAVSSVPAVRTRLVELQRTMAEGPGSI
Mb1739|M.bovis_AF2122/97            DSCYLAGEDVSVEIRGDAVTRAVSAVSSVPAVRTRLVELQRTMAEGPGSI
MMAR_2527|M.marinum_M               SRFFLSGEDVSAEIRGDDVTRAVSAVSAVSSVRQRLVNLQRAMAEGTGSI
MUL_3233|M.ulcerans_Agy99           SKFFLSGEDVSAEIRGDDVTRAVSAVSAVSSVRQRLLNLQRAMAEGTGSI
MLBr_01371|M.leprae_Br4923          DRYFLGGEDVSSEIRTEEVTQAVSAVSAIPAVRVRLVDLQRQMAEGRGSV
MAV_3064|M.avium_104                DRYFLGGEDVSTEIRGDKVTAAVSAVSSIPAVRTRLVGLQREMASGPGSI
TH_0201|M.thermoresistible__bu      QRFYLGAEDVSDEIRGDAVTRAVSAVSAVPEVRERLVALQRQLAAGEDSV
Mflv_3494|M.gilvum_PYR-GCK          DRFLLAGADVSAEIRGDAVTKAVSAVSAVPAVRARLVEIQRQLAAAAGNV
Mvan_3275|M.vanbaalenii_PYR-1       DRSYLAGEDVSTEIRGDAVTKAVSAVSAVPAVRSRLVALQRELASAPDNV
MAB_2371|M.abscessus_ATCC_1997      QTALLAGEDVSVPIRGNEVTGAVSAVSAVPAVRERLVRQQRELAESSGAV
MSMEG_3739|M.smegmatis_MC2_155      DAAFLAGEDVSSEIRGDAVTGAVSAVSAVPAVRTRLVDIQRKLATEGGRV
                                    .   *.. ***  ** : ** ******::. ** **:  ** :*   . :

Rv1712|M.tuberculosis_H37Rv         VVEGRDIGTVVFPDAPVKIFLTASAETRARRRNAQNVAAGLADDYDGVLA
Mb1739|M.bovis_AF2122/97            VVEGRDIGTVVFPDAPVKIFLTASAETRARRRNAQNVAAGLADDYDGVLA
MMAR_2527|M.marinum_M               VVEGRDIGTVVFPDARVKIFLTASAETRARRRNDQNVASGLADNYEAVLA
MUL_3233|M.ulcerans_Agy99           VVEGRDIGTVVFPDARVKIFLTASAETRARRRNDQNVASGLADNYEAVLA
MLBr_01371|M.leprae_Br4923          VVEGRDIGTVVLPDAPVKIFLTASPETRARRRNDQNVASGSADDYDRVLA
MAV_3064|M.avium_104                VVEGRDIGTVVLPDAPVKIFLTASAETRARRRNDQNVAAGLADDYEAVLA
TH_0201|M.thermoresistible__bu      VVEGRDIGTVVFPDADVKIFLTATAEERARRRNAQNVAKGLDDDYAGVLA
Mflv_3494|M.gilvum_PYR-GCK          VVEGRDIGTVVLPDADVKIFLTASAEVRAQRRTDQNIANGRPGDYESVLA
Mvan_3275|M.vanbaalenii_PYR-1       VVEGRDIGTVVLPAADVKIFLTASAEERARRRDAQNVAAGLPGDYEAVLA
MAB_2371|M.abscessus_ATCC_1997      VVEGRDIGTVVLPDADVKIYLTASAQARAQRRNAQNVSGGGDDEYEKVLA
MSMEG_3739|M.smegmatis_MC2_155      VVEGRDIGTVVLPDADVKIFLTASAEERARRRNAQNVANGLPDDYATVLA
                                    ***********:* * ***:***:.: **:**  **:: *  .:*  ***

Rv1712|M.tuberculosis_H37Rv         DVRRRDHLDSTRAVSPLQAAGDAVIVDTSDMTEAEVVAHLLELVTRRSEA
Mb1739|M.bovis_AF2122/97            DVRRRDHLDSTRAVSPLQAAGDAVIVDTSDMTEAEVVAHLLELVTRRSEA
MMAR_2527|M.marinum_M               DVRRRDHLDSTRAVSPLRAAADAIVVDTSEMTEAEVIAHLTELVTQRSGA
MUL_3233|M.ulcerans_Agy99           DVRRRDHLDSTRAVSPLRAAADAIVVDTSEMTEAEVIAHLTELVTQRSGA
MLBr_01371|M.leprae_Br4923          EVRRRDHLDSTRAVSPLYVAQDAMIVDTSKMAEAEVIAHLMDLVKQRSGA
MAV_3064|M.avium_104                EVRRRDHLDSTRRVSPLRAAPDAVVVDTSDMTEAQVIDHLRDLVRQRSEV
TH_0201|M.thermoresistible__bu      DVQRRDRLDSSRAVAPLRAAADAVVVDTSDMTEQQVVEHLTALVAEQAGA
Mflv_3494|M.gilvum_PYR-GCK          DVRRRDHLDSTRAVSPLRAAEDAIVVDTSDMNQSEVVARLAELVEQRAGV
Mvan_3275|M.vanbaalenii_PYR-1       DVRRRDHLDSTRAVSPLRAAEDAVVVDTSDMNQAEVVAYLTELVEQKAGV
MAB_2371|M.abscessus_ATCC_1997      DVQRRDHLDSTRAVSPLRPAEDALEVDTSDMTQEQVVAHLLDLVRTRAGA
MSMEG_3739|M.smegmatis_MC2_155      DVQRRDHLDSTRPVSPLRAADDALVVDTSDMDQAQVIAHLLDLVTAQAGA
                                    :*:***:***:* *:**  * **: ****.* : :*:  *  **  :: .

Rv1712|M.tuberculosis_H37Rv         VR
Mb1739|M.bovis_AF2122/97            VR
MMAR_2527|M.marinum_M               AR
MUL_3233|M.ulcerans_Agy99           AR
MLBr_01371|M.leprae_Br4923          VW
MAV_3064|M.avium_104                AR
TH_0201|M.thermoresistible__bu      PR
Mflv_3494|M.gilvum_PYR-GCK          SR
Mvan_3275|M.vanbaalenii_PYR-1       AR
MAB_2371|M.abscessus_ATCC_1997      SR
MSMEG_3739|M.smegmatis_MC2_155      RR