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VSRLSAAVVAIDGPAGTGKSSVSRRLARELGARFLDTGAMYRIVTLAVLRAGADPSDIAAVETIASTVQM SLGYDPDGDSCYLAGEDVSVEIRGDAVTRAVSAVSSVPAVRTRLVELQRTMAEGPGSIVVEGRDIGTVVF PDAPVKIFLTASAETRARRRNAQNVAAGLADDYDGVLADVRRRDHLDSTRAVSPLQAAGDAVIVDTSDMT EAEVVAHLLELVTRRSEAVR
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. tuberculosis H37Rv | Rv1712 | cmk | - | 100% (230) | cytidylate kinase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1739 | cmk | 1e-123 | 100.00% (230) | cytidylate kinase |
M. gilvum PYR-GCK | Mflv_3494 | cmk | 2e-80 | 68.61% (223) | cytidylate kinase |
M. leprae Br4923 | MLBr_01371 | cmk | 7e-85 | 74.77% (222) | cytidylate kinase |
M. abscessus ATCC 19977 | MAB_2371 | - | 1e-78 | 68.16% (223) | cytidylate kinase (Cmk) |
M. marinum M | MMAR_2527 | cmk | 2e-93 | 78.92% (223) | cytidylate kinase, Cmk |
M. avium 104 | MAV_3064 | cmk | 9e-93 | 78.48% (223) | cytidylate kinase |
M. smegmatis MC2 155 | MSMEG_3739 | cmk | 3e-86 | 73.99% (223) | cytidylate kinase |
M. thermoresistible (build 8) | TH_0201 | cmk | 6e-85 | 73.54% (223) | Probable Cytidylate kinase cmk (CMP kinase) (Cytidine |
M. ulcerans Agy99 | MUL_3233 | cmk | 8e-93 | 78.03% (223) | cytidylate kinase |
M. vanbaalenii PYR-1 | Mvan_3275 | cmk | 9e-87 | 73.09% (223) | cytidylate kinase |
CLUSTAL 2.0.9 multiple sequence alignment Rv1712|M.tuberculosis_H37Rv ----------------------MSRLSAAVVAIDGPAGTGKSSVSRRLAR Mb1739|M.bovis_AF2122/97 ----------------------MSRLSAAVVAIDGPAGTGKSSVSRRLAR MMAR_2527|M.marinum_M MSVGTSGTSVVSAGTSGTSGTNEPAPVGLVVAIDGPAGTGKSSVSRGLAR MUL_3233|M.ulcerans_Agy99 ----------MSAGTSGTSGTNEPAPVGLVVAIDGPAGTGKSSVSRGLAR MLBr_01371|M.leprae_Br4923 -------------------------MTDIVVAIDGPAGTGKSSVSRGLAR MAV_3064|M.avium_104 ------------------------MSADVVVAIDGPAGTGKSSVSKGLAR TH_0201|M.thermoresistible__bu ----------------------------LVVAVDGPAGTGKSSVSKGLAR Mflv_3494|M.gilvum_PYR-GCK ------------------------MSRSLVIAIDGPAGTGKSSVAKGLAR Mvan_3275|M.vanbaalenii_PYR-1 ------------------------MSRSLVIAIDGPAGTGKSSVARGLAV MAB_2371|M.abscessus_ATCC_1997 -----------------------------MVAVDGPSGTGKSSVAKELAR MSMEG_3739|M.smegmatis_MC2_155 ------------------------MSGSLVVAVDGPAGTGKSSVSRGLAR ::*:***:*******:: ** Rv1712|M.tuberculosis_H37Rv ELGARFLDTGAMYRIVTLAVLRAGADPSDIAAVETIASTVQMSLGYDPDG Mb1739|M.bovis_AF2122/97 ELGARFLDTGAMYRIVTLAVLRAGADPSDIAAVETIASTVQMSLGYDPDG MMAR_2527|M.marinum_M GLGSRFLDTGAMYRMVTLAVLRAGIDPADEQAVANCAASAQLSVGYDPDA MUL_3233|M.ulcerans_Agy99 GLGSRFLDTGAMYRMVTLSVLRAGIDPADEQAVADCAASAQLSVGYDPDA MLBr_01371|M.leprae_Br4923 ELGARYLDTGAMYRMMTLAVLRAGIDPADAAAIGESVWKVQMLSDH---- MAV_3064|M.avium_104 ALGARYLDTGGMYRMVTLAVLRAGIDPADADAVGRAAQAVRMSVDYHPDG TH_0201|M.thermoresistible__bu ALGARYLDTGAMYRIVTLAVLRAGVDPGNAEAVAEIADTVQLDVGQSPDD Mflv_3494|M.gilvum_PYR-GCK SLNASYLDTGAMYRIVTLNALRAGVDLDDAAAIAAATDEVDLAVGYDPDE Mvan_3275|M.vanbaalenii_PYR-1 AMGARYLDTGAMYRIVTLGVLRAGVDPADAAAVAAVAAEVELAVGHDPGE MAB_2371|M.abscessus_ATCC_1997 QLGASYLDTGAMYRIVTLWVLRAGVDLTDPAAIAAATDQVPMSVSSDPDA MSMEG_3739|M.smegmatis_MC2_155 ALGARYLDTGAMYRIATLAVLRAGADLTDPAAIEKAAADAEIGVGSDPDV :.: :****.***: ** .**** * : *: . . : . Rv1712|M.tuberculosis_H37Rv DSCYLAGEDVSVEIRGDAVTRAVSAVSSVPAVRTRLVELQRTMAEGPGSI Mb1739|M.bovis_AF2122/97 DSCYLAGEDVSVEIRGDAVTRAVSAVSSVPAVRTRLVELQRTMAEGPGSI MMAR_2527|M.marinum_M SRFFLSGEDVSAEIRGDDVTRAVSAVSAVSSVRQRLVNLQRAMAEGTGSI MUL_3233|M.ulcerans_Agy99 SKFFLSGEDVSAEIRGDDVTRAVSAVSAVSSVRQRLLNLQRAMAEGTGSI MLBr_01371|M.leprae_Br4923 DRYFLGGEDVSSEIRTEEVTQAVSAVSAIPAVRVRLVDLQRQMAEGRGSV MAV_3064|M.avium_104 DRYFLGGEDVSTEIRGDKVTAAVSAVSSIPAVRTRLVGLQREMASGPGSI TH_0201|M.thermoresistible__bu QRFYLGAEDVSDEIRGDAVTRAVSAVSAVPEVRERLVALQRQLAAGEDSV Mflv_3494|M.gilvum_PYR-GCK DRFLLAGADVSAEIRGDAVTKAVSAVSAVPAVRARLVEIQRQLAAAAGNV Mvan_3275|M.vanbaalenii_PYR-1 DRSYLAGEDVSTEIRGDAVTKAVSAVSAVPAVRSRLVALQRELASAPDNV MAB_2371|M.abscessus_ATCC_1997 QTALLAGEDVSVPIRGNEVTGAVSAVSAVPAVRERLVRQQRELAESSGAV MSMEG_3739|M.smegmatis_MC2_155 DAAFLAGEDVSSEIRGDAVTGAVSAVSAVPAVRTRLVDIQRKLATEGGRV . *.. *** ** : ** ******::. ** **: ** :* . : Rv1712|M.tuberculosis_H37Rv VVEGRDIGTVVFPDAPVKIFLTASAETRARRRNAQNVAAGLADDYDGVLA Mb1739|M.bovis_AF2122/97 VVEGRDIGTVVFPDAPVKIFLTASAETRARRRNAQNVAAGLADDYDGVLA MMAR_2527|M.marinum_M VVEGRDIGTVVFPDARVKIFLTASAETRARRRNDQNVASGLADNYEAVLA MUL_3233|M.ulcerans_Agy99 VVEGRDIGTVVFPDARVKIFLTASAETRARRRNDQNVASGLADNYEAVLA MLBr_01371|M.leprae_Br4923 VVEGRDIGTVVLPDAPVKIFLTASPETRARRRNDQNVASGSADDYDRVLA MAV_3064|M.avium_104 VVEGRDIGTVVLPDAPVKIFLTASAETRARRRNDQNVAAGLADDYEAVLA TH_0201|M.thermoresistible__bu VVEGRDIGTVVFPDADVKIFLTATAEERARRRNAQNVAKGLDDDYAGVLA Mflv_3494|M.gilvum_PYR-GCK VVEGRDIGTVVLPDADVKIFLTASAEVRAQRRTDQNIANGRPGDYESVLA Mvan_3275|M.vanbaalenii_PYR-1 VVEGRDIGTVVLPAADVKIFLTASAEERARRRDAQNVAAGLPGDYEAVLA MAB_2371|M.abscessus_ATCC_1997 VVEGRDIGTVVLPDADVKIYLTASAQARAQRRNAQNVSGGGDDEYEKVLA MSMEG_3739|M.smegmatis_MC2_155 VVEGRDIGTVVLPDADVKIFLTASAEERARRRNAQNVANGLPDDYATVLA ***********:* * ***:***:.: **:** **:: * .:* *** Rv1712|M.tuberculosis_H37Rv DVRRRDHLDSTRAVSPLQAAGDAVIVDTSDMTEAEVVAHLLELVTRRSEA Mb1739|M.bovis_AF2122/97 DVRRRDHLDSTRAVSPLQAAGDAVIVDTSDMTEAEVVAHLLELVTRRSEA MMAR_2527|M.marinum_M DVRRRDHLDSTRAVSPLRAAADAIVVDTSEMTEAEVIAHLTELVTQRSGA MUL_3233|M.ulcerans_Agy99 DVRRRDHLDSTRAVSPLRAAADAIVVDTSEMTEAEVIAHLTELVTQRSGA MLBr_01371|M.leprae_Br4923 EVRRRDHLDSTRAVSPLYVAQDAMIVDTSKMAEAEVIAHLMDLVKQRSGA MAV_3064|M.avium_104 EVRRRDHLDSTRRVSPLRAAPDAVVVDTSDMTEAQVIDHLRDLVRQRSEV TH_0201|M.thermoresistible__bu DVQRRDRLDSSRAVAPLRAAADAVVVDTSDMTEQQVVEHLTALVAEQAGA Mflv_3494|M.gilvum_PYR-GCK DVRRRDHLDSTRAVSPLRAAEDAIVVDTSDMNQSEVVARLAELVEQRAGV Mvan_3275|M.vanbaalenii_PYR-1 DVRRRDHLDSTRAVSPLRAAEDAVVVDTSDMNQAEVVAYLTELVEQKAGV MAB_2371|M.abscessus_ATCC_1997 DVQRRDHLDSTRAVSPLRPAEDALEVDTSDMTQEQVVAHLLDLVRTRAGA MSMEG_3739|M.smegmatis_MC2_155 DVQRRDHLDSTRPVSPLRAADDALVVDTSDMDQAQVIAHLLDLVTAQAGA :*:***:***:* *:** * **: ****.* : :*: * ** :: . Rv1712|M.tuberculosis_H37Rv VR Mb1739|M.bovis_AF2122/97 VR MMAR_2527|M.marinum_M AR MUL_3233|M.ulcerans_Agy99 AR MLBr_01371|M.leprae_Br4923 VW MAV_3064|M.avium_104 AR TH_0201|M.thermoresistible__bu PR Mflv_3494|M.gilvum_PYR-GCK SR Mvan_3275|M.vanbaalenii_PYR-1 AR MAB_2371|M.abscessus_ATCC_1997 SR MSMEG_3739|M.smegmatis_MC2_155 RR