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VTAHRSVLLVVHTGRDEATETARRVEKVLGDNKIALRVLSAEAVDRGSLHLAPDDMRAMGVEIEVVDADQ HAADGCELVLVLGGDGTFLRAAELARNASIPVLGVNLGRIGFLAEAEAEAIDAVLEHVVAQDYRVEDRLT LDVVVRQGGRIVNRGWALNEVSLEKGPRLGVLGVVVEIDGRPVSAFGCDGVLVSTPTGSTAYAFSAGGPV LWPDLEAILVVPNNAHALFGRPMVTSPEATIAIEIEADGHDALVFCDGRREMLIPAGSRLEVTRCVTSVK WARLDSAPFTDRLVRKFRLPVTGWRGK
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1695 | ppnK | - | 100% (307) | inorganic polyphosphate/ATP-NAD kinase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1721 | ppnK | 1e-174 | 100.00% (307) | inorganic polyphosphate/ATP-NAD kinase |
| M. gilvum PYR-GCK | Mflv_3508 | ppnK | 1e-147 | 83.17% (303) | inorganic polyphosphate/ATP-NAD kinase |
| M. leprae Br4923 | MLBr_01359 | ppnK | 1e-155 | 87.87% (305) | inorganic polyphosphate/ATP-NAD kinase |
| M. abscessus ATCC 19977 | MAB_2360 | ppnK | 1e-136 | 77.23% (303) | inorganic polyphosphate/ATP-NAD kinase |
| M. marinum M | MMAR_2500 | ppnK | 1e-159 | 91.53% (307) | inorganic polyphosphate/ATP-NAD kinase, PpnK |
| M. avium 104 | MAV_3076 | ppnK | 1e-156 | 91.12% (304) | inorganic polyphosphate/ATP-NAD kinase |
| M. smegmatis MC2 155 | MSMEG_3750 | ppnK | 1e-148 | 83.39% (307) | inorganic polyphosphate/ATP-NAD kinase |
| M. thermoresistible (build 8) | TH_1549 | - | 1e-137 | 76.22% (307) | Inorganic polyphosphate/ATP-NAD kinase ppnK (Poly(P)/ATP NAD |
| M. ulcerans Agy99 | MUL_1684 | ppnK | 1e-159 | 91.21% (307) | inorganic polyphosphate/ATP-NAD kinase |
| M. vanbaalenii PYR-1 | Mvan_3289 | ppnK | 1e-150 | 83.83% (303) | inorganic polyphosphate/ATP-NAD kinase |
CLUSTAL 2.0.9 multiple sequence alignment
Rv1695|M.tuberculosis_H37Rv -------MT----AHRSVLLVVHTGRDEATETARRVEKVLGDNKIALRVL
Mb1721|M.bovis_AF2122/97 -------MT----AHRSVLLVVHTGRDEATETARRVEKVLGDNKIALRVL
MMAR_2500|M.marinum_M -------MT----ATRTVLLVVHTGRDEATETARRVEKVLGDNGIALRVL
MUL_1684|M.ulcerans_Agy99 -------MT----ATRTVLLVVHTGRDEATETARRVEKVLGDNGIALRVL
MAV_3076|M.avium_104 -------MTP---AERTVLMVVHTGREEATETARRVQKVLGDNGIALRVL
MLBr_01359|M.leprae_Br4923 -------MTPRKAAQRTVLLVVHTGRDEATETARRVKKIVGDNGIALRVL
MAB_2360|M.abscessus_ATCC_1997 -------MN-----ERKILLVAHTGRDEVTETARRVAKTLGENGIALRVL
Mflv_3508|M.gilvum_PYR-GCK MTAPVTDNS----PERTILLVVHTGRPEATEVARRVEKVLADHGIGLRVL
Mvan_3289|M.vanbaalenii_PYR-1 --------M----TERTILLVVHTGREEVTEVARRVEKVLSDHGIGLRAL
MSMEG_3750|M.smegmatis_MC2_155 -------MT----VERSILLVVHTGRDEATEVARRVEKVLGDNGIGLRVL
TH_1549|M.thermoresistible__bu -------VN----RERNILLVVNPGRDEVTEVARRVEKILGDNGIGLRML
*.:*:*.:.** *.**.**** * :.:: *.** *
Rv1695|M.tuberculosis_H37Rv SAEAVDRGSLHLAPDDMRAMGVEIEVVDADQHAADGCELVLVLGGDGTFL
Mb1721|M.bovis_AF2122/97 SAEAVDRGSLHLAPDDMRAMGVEIEVVDADQHAADGCELVLVLGGDGTFL
MMAR_2500|M.marinum_M SAEAVDRGSLHLAPDDMRALGVDIEVVDADPRAADGCELVLVLGGDGTFL
MUL_1684|M.ulcerans_Agy99 SAEAVDRGSLHLAPDDMRALGIDIEVVDADPRAADGCELVLVLGGDGTFL
MAV_3076|M.avium_104 SAEAVDRGPLHLAPDDMRAMGVEIEVVDADPLAARGCELVLVLGGDGTFL
MLBr_01359|M.leprae_Br4923 SAEAVDRGSLHLALDNMRAMGVDIEVVDADPHVAQGCELVLVLGGDGTFL
MAB_2360|M.abscessus_ATCC_1997 SAEAIDRGPVHLDPSEFRSLGVDVEVVDADQDAATGCELVLVLGGDGTFL
Mflv_3508|M.gilvum_PYR-GCK SAEAVDRGPLHLSPDDMRALGADIEVVDPEERAAEGCELVLVLGGDGTFL
Mvan_3289|M.vanbaalenii_PYR-1 SAEAVDRGPVHLAPDDMRALGVEIDVVDADERAAEGCELVLVLGGDGTFL
MSMEG_3750|M.smegmatis_MC2_155 SAEAVDHGSVHLAPDEMRALGVQIDVVDPDERAAEGCELVLVLGGDGSFL
TH_1549|M.thermoresistible__bu SAAAVDRGSMGHDSDGMPDLGDEVDVVDAEERAAEGCEVVIVLGGDGTFL
** *:*:*.: . : :* :::***.: .* ***:*:******:**
Rv1695|M.tuberculosis_H37Rv RAAELARNASIPVLGVNLGRIGFLAEAEAEAIDAVLEHVVAQDYRVEDRL
Mb1721|M.bovis_AF2122/97 RAAELARNASIPVLGVNLGRIGFLAEAEAEAIDAVLEHVVAQDYRVEDRL
MMAR_2500|M.marinum_M RAAELARNAQIPVLGVNLGRIGFLAEAEAEAIDRVLDHVVARDYRVEERL
MUL_1684|M.ulcerans_Agy99 RAAELARNAQIPVLGVNLGRIGFLAEAEAEAIDRVLDHVVARDYRVEERL
MAV_3076|M.avium_104 RAAELARNADIPVLGVNLGRIGFLAEAEAEAIDKVLEHVVARDYRVENRM
MLBr_01359|M.leprae_Br4923 RAAELARTARIPVLGVNLGRIGFLAEAEAEAIDVVLEHVIARSYRVEERL
MAB_2360|M.abscessus_ATCC_1997 RAAELARSATAPVLGVNLGRIGFLAEVEAEAIDSVLTHVVEGTYRVETRM
Mflv_3508|M.gilvum_PYR-GCK RAAELARNAEIPVLGVNLGKIGFLAEAEAEAIDTVLDHIVRRDYRVEERM
Mvan_3289|M.vanbaalenii_PYR-1 RAAELARNAEIPVLGVNLGKIGFLAEAEAESIDSVLDHIVRRDYRVEERM
MSMEG_3750|M.smegmatis_MC2_155 RAAELARNVGIPVLGVNLGRIGFLAEAEAEAIDMVLDHVIRRDYVVEERM
TH_1549|M.thermoresistible__bu RAAELARNVDIPVLGVNLGRIGFLAEAEADSIDHVLERVVARDYRIEHRM
*******.. ********:******.**::** ** ::: * :* *:
Rv1695|M.tuberculosis_H37Rv TLDVVVRQGGRIVNRGWALNEVSLEKGPRLGVLGVVVEIDGRPVSAFGCD
Mb1721|M.bovis_AF2122/97 TLDVVVRQGGRIVNRGWALNEVSLEKGPRLGVLGVVVEIDGRPVSAFGCD
MMAR_2500|M.marinum_M TLDVVVRKAGCDLEKGWALNEVSLEKGPRLGVLGVVVEIDGRPVSAFGCD
MUL_1684|M.ulcerans_Agy99 TLDVVVRKAGCDLERGWALNEVSLEKGPRLGVLGVVVEIDGRSVSAFGCD
MAV_3076|M.avium_104 TLDVVVRHHGTVSDHGWALNEVSLEKGPRLGVLGVVVEIDGRPVSAFGCD
MLBr_01359|M.leprae_Br4923 TLDIVVRQGGNIIDQGWALNEASLEKGPRLGVLGVVVEIEGRPVSTFGCD
MAB_2360|M.abscessus_ATCC_1997 TLDVLVRIGDEVAERGWALNEVSIEKGPRLGVLGVVLEVDARPVSAFGCD
Mflv_3508|M.gilvum_PYR-GCK TLDVAVRAKGEIIDHGWALNEASLEKGPRLGVLGVVVEVDGRPVSSFGCD
Mvan_3289|M.vanbaalenii_PYR-1 TLEVAVRAGGRLLDRGWALNEASLEKGPRLGVLGVVVEVDGRPVSSFGCD
MSMEG_3750|M.smegmatis_MC2_155 TLDVAVRAHNEIISRGWALNEASLEKGPRLGVLGVVLEVDGRPVSAFGCD
TH_1549|M.thermoresistible__bu TLDIAVRVDGRVVNRGWALNEASLEKGPRLGVLGALLEVDGRPVSSFGCD
**:: ** . .:******.*:**********.::*::.*.**:****
Rv1695|M.tuberculosis_H37Rv GVLVSTPTGSTAYAFSAGGPVLWPDLEAILVVPNNAHALFGRPMVTSPEA
Mb1721|M.bovis_AF2122/97 GVLVSTPTGSTAYAFSAGGPVLWPDLEAILVVPNNAHALFGRPMVTSPEA
MMAR_2500|M.marinum_M GVLVSTPTGSTAYAFSAGGPVLWPDLEAILVVPNNAHALFGRPMVTSPEA
MUL_1684|M.ulcerans_Agy99 GVLVSTPTGSTAYAFSAGGPVLWPDLEAILVVPNNAHALFGRPMVTSPEA
MAV_3076|M.avium_104 GVLVSTPTGSTAYAFSAGGPVLWPDLEAILVVPNNAHALFGRPMVTSPAA
MLBr_01359|M.leprae_Br4923 GVLVSTPTGSTAYAFSAGGPVLWPDLEAILVVPNNAHALFGRPMVTSPDA
MAB_2360|M.abscessus_ATCC_1997 GVLISTPTGSTAYAFSAGGPVVWPDLDAILVVPNNAHALFARPMVTSPAA
Mflv_3508|M.gilvum_PYR-GCK GVLVSTPTGSTAYAFSAGGPVLWPDLEAIIVVPNNAHALFARPMVTSPDA
Mvan_3289|M.vanbaalenii_PYR-1 GVLVSTPTGSTAYAFSAGGPVLWPDLEAIIVVPNNAHALFARPMVTSPDA
MSMEG_3750|M.smegmatis_MC2_155 GVLVSTPTGSTAYAFSAGGPVLWPDLEAILVVPNNAHALFARPMVTSPEA
TH_1549|M.thermoresistible__bu GVLVSTPTGSTAYAFSAGGPVVWPDLEVILVVPNNAHALFARPMVTSPES
***:*****************:****:.*:**********.******* :
Rv1695|M.tuberculosis_H37Rv TIAIEIEADGHDALVFCDGRREMLIPAGSRLEVTRCVTSVKWARLDSAPF
Mb1721|M.bovis_AF2122/97 TIAIEIEADGHDALVFCDGRREMLIPAGSRLEVTRCVTSVKWARLDSAPF
MMAR_2500|M.marinum_M TIAVEIEPDGHDAMVFCDGRREMLMPAGSRLEVTRCDTPVKWARLDSAPF
MUL_1684|M.ulcerans_Agy99 TIAVEIEPDGHDAMVFCDGRREMLMPAGSRLEVTRCDTPVKWARLDSAPF
MAV_3076|M.avium_104 TIAIEIEADGHDALVFCDGRREMLIPAGSRIEVKRCDTAVKWARLDSAPF
MLBr_01359|M.leprae_Br4923 TVAIELEANGNDALVFCDGRREMIIPAGGRLEVTRCATPVKWARLDSAPF
MAB_2360|M.abscessus_ATCC_1997 TVAVEIEADGHDALLFCDGRREIRVPPGGRVEVVRGHQPVLWARLDSKPF
Mflv_3508|M.gilvum_PYR-GCK AIAIEIEASGYDALVFCDGRREMVLPAGGRLEVTRCATPLKWVRLDSAPF
Mvan_3289|M.vanbaalenii_PYR-1 LIAIEIEATGHDALVFCDGRREMVVPAGGRLEVTRCATPLKWVRLDSAPF
MSMEG_3750|M.smegmatis_MC2_155 CIAIEVEAGGNDALVFCDGRRDMVVPAGGRLEVTRCGTPVKWVRLDSAPF
TH_1549|M.thermoresistible__bu TIAVEVEANGHDAVVFCDGRRKMVVPAGGRVEVTRSATPVKWVRLYSAPF
:*:*:*. * **::******.: :*.*.*:** * .: *.** * **
Rv1695|M.tuberculosis_H37Rv TDRLVRKFRLPVTGWRGK
Mb1721|M.bovis_AF2122/97 TDRLVRKFRLPVTGWRGK
MMAR_2500|M.marinum_M TDRLVHKFRLPVTGWRGK
MUL_1684|M.ulcerans_Agy99 TDRLVHKFRLPVTGWRGK
MAV_3076|M.avium_104 TDRLVRKFRLPVTGWRGN
MLBr_01359|M.leprae_Br4923 TDRLVSKFRLPVTGWRGK
MAB_2360|M.abscessus_ATCC_1997 ADRVVRKFQLPVKGWRGR
Mflv_3508|M.gilvum_PYR-GCK TDRLVRKFRLPVTGWRGQ
Mvan_3289|M.vanbaalenii_PYR-1 TDRLVRKFRLPVTGWRGQ
MSMEG_3750|M.smegmatis_MC2_155 TDRLVRKFRLPVTGWRGQ
TH_1549|M.thermoresistible__bu ADRLVRKFRLPVTGWRGQ
:**:* **:***.****.