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M. abscessus ATCC 19977 MAB_2360 (ppnK)

annotation: inorganic polyphosphate/ATP-NAD kinase
coordinates: 2415048 - 2415968
length: 306

VNERKILLVAHTGRDEVTETARRVAKTLGENGIALRVLSAEAIDRGPVHLDPSEFRSLGVDVEVVDADQD
AATGCELVLVLGGDGTFLRAAELARSATAPVLGVNLGRIGFLAEVEAEAIDSVLTHVVEGTYRVETRMTL
DVLVRIGDEVAERGWALNEVSIEKGPRLGVLGVVLEVDARPVSAFGCDGVLISTPTGSTAYAFSAGGPVV
WPDLDAILVVPNNAHALFARPMVTSPAATVAVEIEADGHDALLFCDGRREIRVPPGGRVEVVRGHQPVLW
ARLDSKPFADRVVRKFQLPVKGWRGR
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. abscessus ATCC 19977MAB_2360ppnK-100% (306)inorganic polyphosphate/ATP-NAD kinase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1721ppnK1e-13677.23% (303) inorganic polyphosphate/ATP-NAD kinase
M. gilvum PYR-GCKMflv_3508ppnK1e-13174.01% (304) inorganic polyphosphate/ATP-NAD kinase
M. tuberculosis H37RvRv1695ppnK1e-13677.23% (303) inorganic polyphosphate/ATP-NAD kinase
M. leprae Br4923MLBr_01359ppnK1e-13274.01% (304) inorganic polyphosphate/ATP-NAD kinase
M. marinum MMMAR_2500ppnK1e-13477.23% (303) inorganic polyphosphate/ATP-NAD kinase, PpnK
M. avium 104MAV_3076ppnK1e-13677.56% (303) inorganic polyphosphate/ATP-NAD kinase
M. smegmatis MC2 155MSMEG_3750ppnK1e-13275.66% (304) inorganic polyphosphate/ATP-NAD kinase
M. thermoresistible (build 8)TH_1549-1e-12571.71% (304) Inorganic polyphosphate/ATP-NAD kinase ppnK (Poly(P)/ATP NAD
M. ulcerans Agy99MUL_1684ppnK1e-13476.90% (303) inorganic polyphosphate/ATP-NAD kinase
M. vanbaalenii PYR-1Mvan_3289ppnK1e-13374.84% (306) inorganic polyphosphate/ATP-NAD kinase

CLUSTAL 2.0.9 multiple sequence alignment


Mb1721|M.bovis_AF2122/97            -------MT----AHRSVLLVVHTGRDEATETARRVEKVLGDNKIALRVL
Rv1695|M.tuberculosis_H37Rv         -------MT----AHRSVLLVVHTGRDEATETARRVEKVLGDNKIALRVL
MMAR_2500|M.marinum_M               -------MT----ATRTVLLVVHTGRDEATETARRVEKVLGDNGIALRVL
MUL_1684|M.ulcerans_Agy99           -------MT----ATRTVLLVVHTGRDEATETARRVEKVLGDNGIALRVL
MAV_3076|M.avium_104                -------MTP---AERTVLMVVHTGREEATETARRVQKVLGDNGIALRVL
MLBr_01359|M.leprae_Br4923          -------MTPRKAAQRTVLLVVHTGRDEATETARRVKKIVGDNGIALRVL
MAB_2360|M.abscessus_ATCC_1997      -------MN-----ERKILLVAHTGRDEVTETARRVAKTLGENGIALRVL
Mflv_3508|M.gilvum_PYR-GCK          MTAPVTDNS----PERTILLVVHTGRPEATEVARRVEKVLADHGIGLRVL
Mvan_3289|M.vanbaalenii_PYR-1       --------M----TERTILLVVHTGREEVTEVARRVEKVLSDHGIGLRAL
MSMEG_3750|M.smegmatis_MC2_155      -------MT----VERSILLVVHTGRDEATEVARRVEKVLGDNGIGLRVL
TH_1549|M.thermoresistible__bu      -------VN----RERNILLVVNPGRDEVTEVARRVEKILGDNGIGLRML
                                                   *.:*:*.:.** *.**.**** * :.:: *.** *

Mb1721|M.bovis_AF2122/97            SAEAVDRGSLHLAPDDMRAMGVEIEVVDADQHAADGCELVLVLGGDGTFL
Rv1695|M.tuberculosis_H37Rv         SAEAVDRGSLHLAPDDMRAMGVEIEVVDADQHAADGCELVLVLGGDGTFL
MMAR_2500|M.marinum_M               SAEAVDRGSLHLAPDDMRALGVDIEVVDADPRAADGCELVLVLGGDGTFL
MUL_1684|M.ulcerans_Agy99           SAEAVDRGSLHLAPDDMRALGIDIEVVDADPRAADGCELVLVLGGDGTFL
MAV_3076|M.avium_104                SAEAVDRGPLHLAPDDMRAMGVEIEVVDADPLAARGCELVLVLGGDGTFL
MLBr_01359|M.leprae_Br4923          SAEAVDRGSLHLALDNMRAMGVDIEVVDADPHVAQGCELVLVLGGDGTFL
MAB_2360|M.abscessus_ATCC_1997      SAEAIDRGPVHLDPSEFRSLGVDVEVVDADQDAATGCELVLVLGGDGTFL
Mflv_3508|M.gilvum_PYR-GCK          SAEAVDRGPLHLSPDDMRALGADIEVVDPEERAAEGCELVLVLGGDGTFL
Mvan_3289|M.vanbaalenii_PYR-1       SAEAVDRGPVHLAPDDMRALGVEIDVVDADERAAEGCELVLVLGGDGTFL
MSMEG_3750|M.smegmatis_MC2_155      SAEAVDHGSVHLAPDEMRALGVQIDVVDPDERAAEGCELVLVLGGDGSFL
TH_1549|M.thermoresistible__bu      SAAAVDRGSMGHDSDGMPDLGDEVDVVDAEERAAEGCEVVIVLGGDGTFL
                                    ** *:*:*.:    . :  :* :::***.:  .* ***:*:******:**

Mb1721|M.bovis_AF2122/97            RAAELARNASIPVLGVNLGRIGFLAEAEAEAIDAVLEHVVAQDYRVEDRL
Rv1695|M.tuberculosis_H37Rv         RAAELARNASIPVLGVNLGRIGFLAEAEAEAIDAVLEHVVAQDYRVEDRL
MMAR_2500|M.marinum_M               RAAELARNAQIPVLGVNLGRIGFLAEAEAEAIDRVLDHVVARDYRVEERL
MUL_1684|M.ulcerans_Agy99           RAAELARNAQIPVLGVNLGRIGFLAEAEAEAIDRVLDHVVARDYRVEERL
MAV_3076|M.avium_104                RAAELARNADIPVLGVNLGRIGFLAEAEAEAIDKVLEHVVARDYRVENRM
MLBr_01359|M.leprae_Br4923          RAAELARTARIPVLGVNLGRIGFLAEAEAEAIDVVLEHVIARSYRVEERL
MAB_2360|M.abscessus_ATCC_1997      RAAELARSATAPVLGVNLGRIGFLAEVEAEAIDSVLTHVVEGTYRVETRM
Mflv_3508|M.gilvum_PYR-GCK          RAAELARNAEIPVLGVNLGKIGFLAEAEAEAIDTVLDHIVRRDYRVEERM
Mvan_3289|M.vanbaalenii_PYR-1       RAAELARNAEIPVLGVNLGKIGFLAEAEAESIDSVLDHIVRRDYRVEERM
MSMEG_3750|M.smegmatis_MC2_155      RAAELARNVGIPVLGVNLGRIGFLAEAEAEAIDMVLDHVIRRDYVVEERM
TH_1549|M.thermoresistible__bu      RAAELARNVDIPVLGVNLGRIGFLAEAEADSIDHVLERVVARDYRIEHRM
                                    *******..  ********:******.**::** ** :::   * :* *:

Mb1721|M.bovis_AF2122/97            TLDVVVRQGGRIVNRGWALNEVSLEKGPRLGVLGVVVEIDGRPVSAFGCD
Rv1695|M.tuberculosis_H37Rv         TLDVVVRQGGRIVNRGWALNEVSLEKGPRLGVLGVVVEIDGRPVSAFGCD
MMAR_2500|M.marinum_M               TLDVVVRKAGCDLEKGWALNEVSLEKGPRLGVLGVVVEIDGRPVSAFGCD
MUL_1684|M.ulcerans_Agy99           TLDVVVRKAGCDLERGWALNEVSLEKGPRLGVLGVVVEIDGRSVSAFGCD
MAV_3076|M.avium_104                TLDVVVRHHGTVSDHGWALNEVSLEKGPRLGVLGVVVEIDGRPVSAFGCD
MLBr_01359|M.leprae_Br4923          TLDIVVRQGGNIIDQGWALNEASLEKGPRLGVLGVVVEIEGRPVSTFGCD
MAB_2360|M.abscessus_ATCC_1997      TLDVLVRIGDEVAERGWALNEVSIEKGPRLGVLGVVLEVDARPVSAFGCD
Mflv_3508|M.gilvum_PYR-GCK          TLDVAVRAKGEIIDHGWALNEASLEKGPRLGVLGVVVEVDGRPVSSFGCD
Mvan_3289|M.vanbaalenii_PYR-1       TLEVAVRAGGRLLDRGWALNEASLEKGPRLGVLGVVVEVDGRPVSSFGCD
MSMEG_3750|M.smegmatis_MC2_155      TLDVAVRAHNEIISRGWALNEASLEKGPRLGVLGVVLEVDGRPVSAFGCD
TH_1549|M.thermoresistible__bu      TLDIAVRVDGRVVNRGWALNEASLEKGPRLGVLGALLEVDGRPVSSFGCD
                                    **:: **  .   .:******.*:**********.::*::.*.**:****

Mb1721|M.bovis_AF2122/97            GVLVSTPTGSTAYAFSAGGPVLWPDLEAILVVPNNAHALFGRPMVTSPEA
Rv1695|M.tuberculosis_H37Rv         GVLVSTPTGSTAYAFSAGGPVLWPDLEAILVVPNNAHALFGRPMVTSPEA
MMAR_2500|M.marinum_M               GVLVSTPTGSTAYAFSAGGPVLWPDLEAILVVPNNAHALFGRPMVTSPEA
MUL_1684|M.ulcerans_Agy99           GVLVSTPTGSTAYAFSAGGPVLWPDLEAILVVPNNAHALFGRPMVTSPEA
MAV_3076|M.avium_104                GVLVSTPTGSTAYAFSAGGPVLWPDLEAILVVPNNAHALFGRPMVTSPAA
MLBr_01359|M.leprae_Br4923          GVLVSTPTGSTAYAFSAGGPVLWPDLEAILVVPNNAHALFGRPMVTSPDA
MAB_2360|M.abscessus_ATCC_1997      GVLISTPTGSTAYAFSAGGPVVWPDLDAILVVPNNAHALFARPMVTSPAA
Mflv_3508|M.gilvum_PYR-GCK          GVLVSTPTGSTAYAFSAGGPVLWPDLEAIIVVPNNAHALFARPMVTSPDA
Mvan_3289|M.vanbaalenii_PYR-1       GVLVSTPTGSTAYAFSAGGPVLWPDLEAIIVVPNNAHALFARPMVTSPDA
MSMEG_3750|M.smegmatis_MC2_155      GVLVSTPTGSTAYAFSAGGPVLWPDLEAILVVPNNAHALFARPMVTSPEA
TH_1549|M.thermoresistible__bu      GVLVSTPTGSTAYAFSAGGPVVWPDLEVILVVPNNAHALFARPMVTSPES
                                    ***:*****************:****:.*:**********.******* :

Mb1721|M.bovis_AF2122/97            TIAIEIEADGHDALVFCDGRREMLIPAGSRLEVTRCVTSVKWARLDSAPF
Rv1695|M.tuberculosis_H37Rv         TIAIEIEADGHDALVFCDGRREMLIPAGSRLEVTRCVTSVKWARLDSAPF
MMAR_2500|M.marinum_M               TIAVEIEPDGHDAMVFCDGRREMLMPAGSRLEVTRCDTPVKWARLDSAPF
MUL_1684|M.ulcerans_Agy99           TIAVEIEPDGHDAMVFCDGRREMLMPAGSRLEVTRCDTPVKWARLDSAPF
MAV_3076|M.avium_104                TIAIEIEADGHDALVFCDGRREMLIPAGSRIEVKRCDTAVKWARLDSAPF
MLBr_01359|M.leprae_Br4923          TVAIELEANGNDALVFCDGRREMIIPAGGRLEVTRCATPVKWARLDSAPF
MAB_2360|M.abscessus_ATCC_1997      TVAVEIEADGHDALLFCDGRREIRVPPGGRVEVVRGHQPVLWARLDSKPF
Mflv_3508|M.gilvum_PYR-GCK          AIAIEIEASGYDALVFCDGRREMVLPAGGRLEVTRCATPLKWVRLDSAPF
Mvan_3289|M.vanbaalenii_PYR-1       LIAIEIEATGHDALVFCDGRREMVVPAGGRLEVTRCATPLKWVRLDSAPF
MSMEG_3750|M.smegmatis_MC2_155      CIAIEVEAGGNDALVFCDGRRDMVVPAGGRLEVTRCGTPVKWVRLDSAPF
TH_1549|M.thermoresistible__bu      TIAVEVEANGHDAVVFCDGRRKMVVPAGGRVEVTRSATPVKWVRLYSAPF
                                     :*:*:*. * **::******.: :*.*.*:** *   .: *.** * **

Mb1721|M.bovis_AF2122/97            TDRLVRKFRLPVTGWRGK
Rv1695|M.tuberculosis_H37Rv         TDRLVRKFRLPVTGWRGK
MMAR_2500|M.marinum_M               TDRLVHKFRLPVTGWRGK
MUL_1684|M.ulcerans_Agy99           TDRLVHKFRLPVTGWRGK
MAV_3076|M.avium_104                TDRLVRKFRLPVTGWRGN
MLBr_01359|M.leprae_Br4923          TDRLVSKFRLPVTGWRGK
MAB_2360|M.abscessus_ATCC_1997      ADRVVRKFQLPVKGWRGR
Mflv_3508|M.gilvum_PYR-GCK          TDRLVRKFRLPVTGWRGQ
Mvan_3289|M.vanbaalenii_PYR-1       TDRLVRKFRLPVTGWRGQ
MSMEG_3750|M.smegmatis_MC2_155      TDRLVRKFRLPVTGWRGQ
TH_1549|M.thermoresistible__bu      ADRLVRKFRLPVTGWRGQ
                                    :**:* **:***.****.