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M. tuberculosis H37Rv Rv1619 (-)

annotation: hypothetical protein Rv1619
coordinates: 1818575 - 1820029
length: 484

MVAAAGEPLNCQRANPEVTVKLPSADVVPRLRGRQRVVVHVDSRTARCVGALALVCAACWLIALLAGDYR
HAQWAVAGRLGWSLTVLAAVAFIARGIFLGRPVTAMHATAAGLFLLAGLAAHVLVADLLGEILIAGSGWA
LMWPTSAHPRPEDLPRVWALINATRADSLAPFAMQAGKSHHFSAAGTAALAYRTRIGYAVVSGDPIGDEA
QFPQLVADFAAMCHMHGWRIVVVGCSERRLGLWSDPMVVGQSLRPIPIGRDVVIDVSNFEMTGRRFRNLR
QAVKRTHNFGVTTEIVAEQQLDDQRQAELAEVLAASPSGARTDRGFCMNLDGVLEGRYPGIQLIIARDAS
GRVQGFHRYATAGGGSDMSLDVPWRRRGAPNGIDERLSADMIAAAKDAGVQRLSLAFAAFPDLFGANQLG
RLQRVCRALIHILDPLIALESLYRYLRKFHALDERRYVLISMTQVFALALVLLSLEFVPRRRHL
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv1619--100% (484)hypothetical protein Rv1619
M. tuberculosis H37RvRv1640clysS2e-2927.59% (406) lysyl-tRNA synthetase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1645-0.0100.00% (484) hypothetical protein Mb1645
M. gilvum PYR-GCKMflv_3544lysS3e-2527.44% (379) lysyl-tRNA synthetase
M. leprae Br4923MLBr_01393lysS1e-2429.68% (283) lysyl-tRNA synthetase
M. abscessus ATCC 19977MAB_2636c-1e-14657.79% (462) hypothetical protein MAB_2636c
M. marinum MMMAR_2422-0.076.23% (467) hypothetical protein MMAR_2422
M. avium 104MAV_3168-0.071.65% (462) hypothetical protein MAV_3168
M. smegmatis MC2 155MSMEG_3796lysS1e-2731.51% (292) lysyl-tRNA synthetase
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_1600-0.076.79% (461) hypothetical protein MUL_1600
M. vanbaalenii PYR-1Mvan_3330lysS5e-2630.21% (288) lysyl-tRNA synthetase

CLUSTAL 2.0.9 multiple sequence alignment


Rv1619|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1645|M.bovis_AF2122/97            --------------------------------------------------
MMAR_2422|M.marinum_M               --------------------------------------------------
MUL_1600|M.ulcerans_Agy99           --------------------------------------------------
MAV_3168|M.avium_104                --------------------------------------------------
MAB_2636c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_3544|M.gilvum_PYR-GCK          MTATRLVRAHPESSHRWVPAAAGWIVGVIATLSLLASVSPLVRSIIRVPR
Mvan_3330|M.vanbaalenii_PYR-1       MTPTSLARARPTSSHRWVPAAAGWIVGVIATLSLLASVSPLVRSLIRVPR
MSMEG_3796|M.smegmatis_MC2_155      --------------MAWVPAAAGWTVGVIATLSLIASVSPLVRSLIRVPR
MLBr_01393|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Rv1619|M.tuberculosis_H37Rv         ------------------------MVAAAGEPLNCQRANPEVTVKLPSAD
Mb1645|M.bovis_AF2122/97            ------------------------MVAAAGEPLNCQRANPEVTVKLPSAD
MMAR_2422|M.marinum_M               -----------------------------------------MSVDGSSVE
MUL_1600|M.ulcerans_Agy99           -------------------------------------------MDGSSVE
MAV_3168|M.avium_104                -------------------------------------------MNGPVVD
MAB_2636c|M.abscessus_ATCC_199      -------------------------------------------MLEPAAA
Mflv_3544|M.gilvum_PYR-GCK          EFVDDYIFNFPDTSFAWAFVLALLAAALAARKRIAWWILTGYMVAAAVWN
Mvan_3330|M.vanbaalenii_PYR-1       EWVDDYIFNFPDTSFAWAFVLALLAAALAARKRIAWWILVGYMIAAAGWN
MSMEG_3796|M.smegmatis_MC2_155      EFVNDFIFNFPDTSFAWAFVLALLAAALAARKRIAWWVLVLYLVGAIGWN
MLBr_01393|M.leprae_Br4923          -------------------MLALLAAALTTRKRIAWLLLLGNMVLAAVLN
                                                                               :      

Rv1619|M.tuberculosis_H37Rv         VVPRLRGRQRVVVHVDSRTARCVGALALVCAACWLIALLAGDYRHAQWAV
Mb1645|M.bovis_AF2122/97            VVPRLRGRQRVVVHVDSRTARCVGALALVCAACWLIALLAGDYRHAQWAV
MMAR_2422|M.marinum_M               VVPRVRARERVVVNVDSVTARCVGALAVFCAACWLIALLARNYRHEDWQA
MUL_1600|M.ulcerans_Agy99           VVPRVRARERVVVNVDSVTARCVGALAVFCAVCWLIALLARNYRHEDWQA
MAV_3168|M.avium_104                VAPKPRAGERVVVSADSRAARLIGALGLFCAACWLIQILVHHHSNPSWHY
MAB_2636c|M.abscessus_ATCC_199      TTP-VRIAERIAVHSDSRPARFVSAATLLLVTGWLVLLVAHSG-YLRHPD
Mflv_3544|M.gilvum_PYR-GCK          VTGLLDG-DRWFEDVGEIIGLGFHLAAIASLLLARREFWARVRPGALVKA
Mvan_3330|M.vanbaalenii_PYR-1       IAGLAEGRERWFAEVGEVIGLAFHLAAIAFLLLARKEFWARVRRGALLKA
MSMEG_3796|M.smegmatis_MC2_155      VGDLAAGGDTVADDIGELIGIAFHVAAIVFLVVARKEFWAKVRRGALLKS
MLBr_01393|M.leprae_Br4923          AVDMAANGNTPAETFGENLGFAVHVVAILLLVLSYREFWAKVRRGALFKA
                                            :      ..  .  .    :         : .          

Rv1619|M.tuberculosis_H37Rv         AGRLGWSLTVLAAVAFIARGIFLG------------RPVTAMHATAAGLF
Mb1645|M.bovis_AF2122/97            AGRLGWSLTVLAAVAFIARGIFLG------------RPVTAMHATAAGLF
MMAR_2422|M.marinum_M               AGRLSWSLTVLAAVALIARGIFLG------------RPVTAMHAIVAALI
MUL_1600|M.ulcerans_Agy99           AGRLSWSLTVLAAVALIARGIFLG------------RPVTAMHAIVAALI
MAV_3168|M.avium_104                ADRLAWSLTVLVAVAWIARGIFLG------------RPVTTMHAAVAAFF
MAB_2636c|M.abscessus_ATCC_199      FDEILWPLTVLFCVGFIARGIFLG------------RPVTYGHAAWAGVA
Mflv_3544|M.gilvum_PYR-GCK          AVTLVAGLGVGTLIGWGLLELFPGTLARPDRFWYALNRVGAFAGADAGAF
Mvan_3330|M.vanbaalenii_PYR-1       AATLVASMAVGTLIGWGLLELFPGSLARSDRFLYALNRVSAFAGADAASF
MSMEG_3796|M.smegmatis_MC2_155      AAVLVAGNLIGIVVAWGLLQAFPGTLDPEWRLPYAVNRVSGFATVPTEVF
MLBr_01393|M.leprae_Br4923          AAVLVAGDVIGILLSLGLVELFPGSLARQDRLPYVANRVVGFALADPDLF
                                       :     :   :.      * *            . *       .   

Rv1619|M.tuberculosis_H37Rv         LLAGLAAHVLVADLLGEILIAGSGWALMWPTSAH--PRPEDLPRVWALIN
Mb1645|M.bovis_AF2122/97            LLAGLAAHVLVADLLGEILIAGSGWALMWPTSAH--PRPEDLPRVWALIN
MMAR_2422|M.marinum_M               LVLGLGAHVLSFSLAGELLIAGSGLVLMWPTSAH--PRPEELPRVWALIN
MUL_1600|M.ulcerans_Agy99           LVLGLGAHVLSFSLAGELLIAGSGLVLMWPTSAH--PRPEELPRVWALIN
MAV_3168|M.avium_104                VLAGLGLHVLSFDLLGDVLIAGSGMVLMWPTSSH--PRPADLPRIWELIN
MAB_2636c|M.abscessus_ATCC_199      VMTALGANVLQFERVGEALVVAAGLILMWPTSAR--PQPEALAQVSALID
Mflv_3544|M.gilvum_PYR-GCK          SGHPHVLVNALLGLFGAMALMIAAVVLFQSQRADNALTGEDESAIRGLLE
Mvan_3330|M.vanbaalenii_PYR-1       SGHPHVFVNALLGLFGAVALMVTAIVLFQSQRADNALTGEDESAIRGLLE
MSMEG_3796|M.smegmatis_MC2_155      EGYSHTFLNAIFGLFGALALMAAAIVLFQSQRASNALTGEDESAIRGLLE
MLBr_01393|M.leprae_Br4923          SGKPHVLLNAIFGLFGALALIMATIVLFQSQRADNALTGEDESAIRGLLE
                                                   *   :  :   *: .  :         . :  *::

Rv1619|M.tuberculosis_H37Rv         ATR-ADSLAPFAMQAGKSHHFSAAGTAALAYRTRIGYAVVSGDPIGDEAQ
Mb1645|M.bovis_AF2122/97            ATR-ADSLAPFAMQAGKSHHFSAAGTAALAYRTRIGYAVVSGDPIGDEAQ
MMAR_2422|M.marinum_M               ATS-ADPLAPFAMQAGKCYHFNAAGTAALAYRTRMGFAVVAGDPIGAESQ
MUL_1600|M.ulcerans_Agy99           ATS-ADPLAPFAMQAGKCYHFNAAGTAALAYRTRMGFAVVAGDPIGAESQ
MAV_3168|M.avium_104                ATR-DDALAPFTMQTGKSYHFSADGSAALAYRTRLGIAVVSGDPIGDEAH
MAB_2636c|M.abscessus_ATCC_199      KTS-DDPLAVFAMHSLKSYYFNADRSAAIAYRTRAGFAVVGGDPIGDESR
Mflv_3544|M.gilvum_PYR-GCK          LYGKNDSLGYFATRRDKAVVFAPNGRAAITYRVEVGVCLASGDPVGDPKA
Mvan_3330|M.vanbaalenii_PYR-1       LYGKNDSLGYFATRRDKAVVFAPSGRAAITYRVEVGVCLASGDPVGDPRS
MSMEG_3796|M.smegmatis_MC2_155      LYGKNDSLGYFATRRDKSVVFAPNGRAAITYRVEVGVCLASGDPVGDPKS
MLBr_01393|M.leprae_Br4923          LYGKNDSLGYFATRRDKSVIFAHNGRAAITYRVEIGVCLASGDPVGDPGA
                                         *.*. *: :  *.  *     **::**.. * .:..***:*    

Rv1619|M.tuberculosis_H37Rv         FPQLVADFAAMCHMHGWRIVVVGCSERRLGLWSDPMVVGQSLRPIPIGRD
Mb1645|M.bovis_AF2122/97            FPQLVADFAAMCHMHGWRIVVVGCSERRLGLWSDPMVVGQSLRPIPIGRD
MMAR_2422|M.marinum_M               FPQLIADFAAMCHTHGWRIAVLACSERRLDLWADRAVVGQSLRAVPIGCD
MUL_1600|M.ulcerans_Agy99           FPQLIADFAAMCHTHGWRIAVLACSERRLDLWADRAVVGQSLRAVPIGCD
MAV_3168|M.avium_104                FPELVADFAATCHAHGWRIAVVGCSERRLELWKDSAVLGQTLRPIPIGRD
MAB_2636c|M.abscessus_ATCC_199      FPALVRDFAAMCRSHGWRVAVLGCSEHALPLWTDSRTVGHHLRAVAVGRD
Mflv_3544|M.gilvum_PYR-GCK          WPQAIEAWLTLCETYGWAPGVMGASATGAQAFRQAGLH-----ALQLGDE
Mvan_3330|M.vanbaalenii_PYR-1       WPQAIDAWLKLCQAYGWAPGVMGASAAGAQAFREAGLN-----ALQLGDE
MSMEG_3796|M.smegmatis_MC2_155      WPQAIAAWLQLCQAYGWAPGVMGASLAGAEAYRAAGLN-----ALQLGDE
MLBr_01393|M.leprae_Br4923          WPQAVDAWLELCQTYGWAPGVMGASSQGAQVFRRAGFN-----AIELGDE
                                    :*  :  :   *. :**   *:..*      :           .: :* :

Rv1619|M.tuberculosis_H37Rv         VVIDVSNFEMTGRRFRNLRQAVKRTHNFGVTTEIVAEQQLDDQRQAELAE
Mb1645|M.bovis_AF2122/97            VVIDVSNFEMTGRRFRNLRQAVKRTHNFGVTTEIVAEQQLDDQRQAELAE
MMAR_2422|M.marinum_M               VVIDVRSFAMVGRKFRNLRQAVKRTRNAGITTEIVAEQELDDTRRAELAE
MUL_1600|M.ulcerans_Agy99           VVIDVRSFAMVGRRFRNLRQAVKRTRNAGITTEIVAEQELDDTRRAELAE
MAV_3168|M.avium_104                VVVDVSSFDMVGRKFRNLRQAVKRTHNCGVTTEIVAEQELSDELLAELTE
MAB_2636c|M.abscessus_ATCC_199      VVVDVQAFDLVGRKYRNLRQGVQRTRNAGITTEVVDERALDGALRAELQQ
Mflv_3544|M.gilvum_PYR-GCK          AILHPDDFRLSGPEMRAVRQAVTRARRAGVAVRFRRHRELSPDEMAEVIA
Mvan_3330|M.vanbaalenii_PYR-1       AILHPEDFRLSGPDMRAVRQAVTRARRAGATVRIRRHRELPADEMAAVIE
MSMEG_3796|M.smegmatis_MC2_155      AILHPDRFRLSGPDMRAVRQAVTRARRAGTSVRIRRHRELSPEEMAAVIR
MLBr_01393|M.leprae_Br4923          AILRTAVYKLSGPDMRGVRQAVTRARRAGLTVRIRRHSDISANEMADTIA
                                    .::    : : *   * :**.* *::. * :...  .  :     *    

Rv1619|M.tuberculosis_H37Rv         VLAASPSGARTDRGFCMNLDGVLEGRYPGIQLIIARDASGRVQGFHRYAT
Mb1645|M.bovis_AF2122/97            VLAASPSGARTDRGFCMNLDGVLEGRYPGIQLIIARDASGRVQGFHRYAT
MMAR_2422|M.marinum_M               MLLASPKGARNDRGFCMSLDGVLEGTYPGVQLIIARDVSGRVQGFDRFTT
MUL_1600|M.ulcerans_Agy99           MLLASPKGARNDRGFCMSLDGVLEGTYPGVQLIIARDVSGRVQGFDRFTT
MAV_3168|M.avium_104                VVRESSKGAHADRGFHMNLDGVLEGRFPGILLIIARDATGKVQAFHRYAT
MAB_2636c|M.abscessus_ATCC_199      VMELS-HGGRYERGFSMLLDGALLGRYPGIRLIIARDNLGVVQGFHRYAT
Mflv_3544|M.gilvum_PYR-GCK          HADAWRDTED-ERGFSMALGRLGDPADADCLLVEAVQNGTQVVAMLSLVP
Mvan_3330|M.vanbaalenii_PYR-1       RADAWRDTDD-ERGFSMALGRLGDPADGDCLLVEAVQ-ADQVVAMLSLVP
MSMEG_3796|M.smegmatis_MC2_155      RADAWRDTET-ERGFSMALGRLGDPADDDCLLVEAVQ-GDEVVAMLSLVP
MLBr_01393|M.leprae_Br4923          RADAWRDTEF-ERGFSMALGRLGDPADSDCLLVEAVDRDDHVVAILSLVP
                                               :*** * *.        .  *: * :    * .:   ..

Rv1619|M.tuberculosis_H37Rv         AGGGSDMSLDVPWRRRGAPNGIDERLSADMIAAAKDAGVQRLSLAFAAFP
Mb1645|M.bovis_AF2122/97            AGGGSDMSLDVPWRRRGAPNGIDERLSADMIAAAKDAGVQRLSLAFAAFP
MMAR_2422|M.marinum_M               AGRGSDYSLDVPWRRSGAPNGIDERLSVDMIIAAKDAGAQRLSLAFAAFP
MUL_1600|M.ulcerans_Agy99           AGRGSDYSLDVPWRRSGAPNGIDERLSVDMIIAAKDAGAQRLSLAFAAFP
MAV_3168|M.avium_104                AGGGSDITLDVPWRRRGAPNGLDERLSVDMVMAGKDRGAQRVSLAFAAFP
MAB_2636c|M.abscessus_ATCC_199      SGGGTDVSLDVPWRRPGSPNGIDERLTVDMICRARSEGARRLSLAFAAFP
Mflv_3544|M.gilvum_PYR-GCK          WG-SNGVSLDLMRRAPQSPNGTIELMVSELCLQSESIGISRISLNFAMFR
Mvan_3330|M.vanbaalenii_PYR-1       WG-GNGVSLDLMRRSPQSPNGTIELMVSELCMQSEDIGITRISLNFAMFR
MSMEG_3796|M.smegmatis_MC2_155      WG-SNGVSLDVMRRSPRSPNGTIELMVSELCMQAEDIGISRISLNFAMFR
MLBr_01393|M.leprae_Br4923          WG-TTGVSLDVMRRSPQSPNGTIELMVSELALKGETLGIARISLNFTMFR
                                     *  .. :**:  *   :***  * :  ::   ..  *  *:** *: * 

Rv1619|M.tuberculosis_H37Rv         DLFGA---NQLGRLQRVCRALIHILDPLIALESLYRYLRKFHALDERRYV
Mb1645|M.bovis_AF2122/97            DLFGA---NQLGRLQRVCRALIHILDPLIALESLYRYLRKFHALDERRYV
MMAR_2422|M.marinum_M               EIFDE---CHSSRPQRLFYLLIHLLDPLISLESLYRYLCKFHALDQRRYA
MUL_1600|M.ulcerans_Agy99           EIFDE---CHRSRPQRLFYLLIHLLDPLISLESLYRYLCKFHALDQRRYA
MAV_3168|M.avium_104                EIFED---KNRGWTRRIFYRLTHVLDPLIALESLYRYVRKWHALDGRRYA
MAB_2636c|M.abscessus_ATCC_199      EIFAE---KDRTRPQQICYSAIHMLDPLIALESLYRYLRKFHALGERRYV
Mflv_3544|M.gilvum_PYR-GCK          SAFEQGAQLGAGPVARLWRWLLVFFSRWWQLETLYRSNMKYQPEWVPRYA
Mvan_3330|M.vanbaalenii_PYR-1       SAFEQGAQLGAGPVARLWRWLLVFFSRWWQLETLYRSNMKYQPEWVPRYA
MSMEG_3796|M.smegmatis_MC2_155      SAFEQGAQLGAGPVARLWRALLVFFSKWWQLESLYRSNMKYQPEWVPRYA
MLBr_01393|M.leprae_Br4923          AAFEQGAQLGAGPIARLWRGLLLFFSRWWQLETLYRSNIKYLPDWVPRYA
                                      *            ::      .:.    **:***   *: .    **.

Rv1619|M.tuberculosis_H37Rv         LISMTQVFA-------LALVLLSLEFVPRRRHL-----------------
Mb1645|M.bovis_AF2122/97            LISMTQVFA-------LALVLLSLEFVPRRRHL-----------------
MMAR_2422|M.marinum_M               LITVTQVIP-------LLVVLLSLEFMPRRRHLR----------------
MUL_1600|M.ulcerans_Agy99           LITVTQVIP-------LLVVLLSLEFMPRRRHLR----------------
MAV_3168|M.avium_104                VISMTQIVP-------LLFVLLSLEFLPRRRHL-----------------
MAB_2636c|M.abscessus_ATCC_199      LVQMSTLPL-------VAFALLSLEFMPRLRVNVARGPAA----------
Mflv_3544|M.gilvum_PYR-GCK          CYEDARLVPRVGVASVIAEGFLVLPFSRRHDQPHTGHHIAAPGDLIATGR
Mvan_3330|M.vanbaalenii_PYR-1       CYDDARLVPRVGVASVIAEGFLVLPFSRRHEQPHTGHHIAAPGTLVATGL
MSMEG_3796|M.smegmatis_MC2_155      CYEDARLVPRVGVASVIAEGFLVLPFSRRNKQ-HTGEHIAAPDTLVQSGR
MLBr_01393|M.leprae_Br4923          CYEDARLIPRVGVASVIAEGFLVLPFSR-RGRVHTGHHPAVPARLAESGL
                                        : :         :   :* * *                        

Rv1619|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1645|M.bovis_AF2122/97            --------------------------------------------------
MMAR_2422|M.marinum_M               --------------------------------------------------
MUL_1600|M.ulcerans_Agy99           --------------------------------------------------
MAV_3168|M.avium_104                --------------------------------------------------
MAB_2636c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_3544|M.gilvum_PYR-GCK          LHSDGTAPDRIGPVGDGADDDAA-PRLPEQVRVRMAKLSALQDRGVDAYP
Mvan_3330|M.vanbaalenii_PYR-1       LHSDGTAPDGMGLQADLADDDQ--PRLPEQVRVRMAKLKALQAQGVDAYP
MSMEG_3796|M.smegmatis_MC2_155      LHRDGSAPDVTGLQGELPDADDE-PRLPEQVRVRMAKLKALQGNGVDAYP
MLBr_01393|M.leprae_Br4923          LHHDGSTPDVSGLQTADVDLEVANSRIPEQVRVRLAKLKTLQLNGIDAYP
                                                                                      

Rv1619|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1645|M.bovis_AF2122/97            --------------------------------------------------
MMAR_2422|M.marinum_M               --------------------------------------------------
MUL_1600|M.ulcerans_Agy99           --------------------------------------------------
MAV_3168|M.avium_104                --------------------------------------------------
MAB_2636c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_3544|M.gilvum_PYR-GCK          VGSPPSHTIAEAIAAEEGTEVTVSGRVLRARDYGGVLFGQLRDWSAETQV
Mvan_3330|M.vanbaalenii_PYR-1       VANPPSHTVAQALAAEDGADVAVAGRVLRSRDYGGVLFAQLRDWSGETQL
MSMEG_3796|M.smegmatis_MC2_155      VGQPPSHTVAQALGATDGETLSVAGRVMRIRDYGGVLFAQLRDWSGEVQL
MLBr_01393|M.leprae_Br4923          VGHPPSHTVAQALDADDEGTVSISGRILRIRDYGGVLFAHVRDWSGEIQV
                                                                                      

Rv1619|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1645|M.bovis_AF2122/97            --------------------------------------------------
MMAR_2422|M.marinum_M               --------------------------------------------------
MUL_1600|M.ulcerans_Agy99           --------------------------------------------------
MAV_3168|M.avium_104                --------------------------------------------------
MAB_2636c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_3544|M.gilvum_PYR-GCK          ALDNSALLDGTTTDFTRTVDLGDLIEVTGTMGHTRSGSWSVLVTRWRLIG
Mvan_3330|M.vanbaalenii_PYR-1       VLDNSLLADGSTADFTRTIDLGDLIEVTGTMGRSRSGKWSLLVSGWRLIG
MSMEG_3796|M.smegmatis_MC2_155      LLDNAALTEGETADFTATIDLGDLVEVTGSMGFSRNGTRSLLVERWRLIG
MLBr_01393|M.leprae_Br4923          LLDNLVLECCCIADFTAAIDLGDIVEMTGNMGFSKNGTRSLIVRNWRLIG
                                                                                      

Rv1619|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1645|M.bovis_AF2122/97            --------------------------------------------------
MMAR_2422|M.marinum_M               --------------------------------------------------
MUL_1600|M.ulcerans_Agy99           --------------------------------------------------
MAV_3168|M.avium_104                --------------------------------------------------
MAB_2636c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_3544|M.gilvum_PYR-GCK          KCLRPLPDKWKGLTDQEARVRARYVDLAVNTDARELIKARSAILHAIRET
Mvan_3330|M.vanbaalenii_PYR-1       KCLRPLPDKWKGLTDQEARVRARYVDLAVNTDARELIRARSAVLHAIRET
MSMEG_3796|M.smegmatis_MC2_155      KCLRPLPDKWKGLTDQEARVRARYVDLAVNTEARDLIRARSGALHAIRET
MLBr_01393|M.leprae_Br4923          KCLRPLPNKWKGLTDPEARVRTRYVDLAVNTESRNLIMARSCVLRSVREM
                                                                                      

Rv1619|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1645|M.bovis_AF2122/97            --------------------------------------------------
MMAR_2422|M.marinum_M               --------------------------------------------------
MUL_1600|M.ulcerans_Agy99           --------------------------------------------------
MAV_3168|M.avium_104                --------------------------------------------------
MAB_2636c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_3544|M.gilvum_PYR-GCK          LVGKGFLEVETPILQQIHGGANARPFLTHINAYDLDLYLRIAPELYLKRL
Mvan_3330|M.vanbaalenii_PYR-1       LVAKDFLEVETPILQQIHGGANARPFLTHINAYDLDLYLRIAPELYLKRL
MSMEG_3796|M.smegmatis_MC2_155      LYSKGFLEVETPILQQIHGGANARPFLTHINAYDLDLYLRIAPELYLKRL
MLBr_01393|M.leprae_Br4923          LFAKGFVEVETPILQQIHGGATARPFATRINTYDMDLFLRIAPELYLKRL
                                                                                      

Rv1619|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1645|M.bovis_AF2122/97            --------------------------------------------------
MMAR_2422|M.marinum_M               --------------------------------------------------
MUL_1600|M.ulcerans_Agy99           --------------------------------------------------
MAV_3168|M.avium_104                --------------------------------------------------
MAB_2636c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_3544|M.gilvum_PYR-GCK          CVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQAHADYTVWIDGCREL
Mvan_3330|M.vanbaalenii_PYR-1       CVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQAHADYHVWIDGCREL
MSMEG_3796|M.smegmatis_MC2_155      CVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQAHADYNVWIDGCREL
MLBr_01393|M.leprae_Br4923          CIGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQAHADYLMWIDGCREL
                                                                                      

Rv1619|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1645|M.bovis_AF2122/97            --------------------------------------------------
MMAR_2422|M.marinum_M               --------------------------------------------------
MUL_1600|M.ulcerans_Agy99           --------------------------------------------------
MAV_3168|M.avium_104                --------------------------------------------------
MAB_2636c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_3544|M.gilvum_PYR-GCK          IQNAAMAANGSHVFFRPRED------GVLEPVDISGRWAVKTVHGAVSEA
Mvan_3330|M.vanbaalenii_PYR-1       IQNAAQAANGAQVFMRPRAD------GVLEPVDISGPWTVKTVHGAVSEA
MSMEG_3796|M.smegmatis_MC2_155      IQNAAQAANGAQVFLRPRPNDPA---GTLEPVDISGQWAVKTVHDAVSEA
MLBr_01393|M.leprae_Br4923          IQNAAEAANGTQTLMRPRIEGASGTANHLEPIDISGVWPVKTVYEAVSEA
                                                                                      

Rv1619|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1645|M.bovis_AF2122/97            --------------------------------------------------
MMAR_2422|M.marinum_M               --------------------------------------------------
MUL_1600|M.ulcerans_Agy99           --------------------------------------------------
MAV_3168|M.avium_104                --------------------------------------------------
MAB_2636c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_3544|M.gilvum_PYR-GCK          LGEHIDVDTDLATLRRLCDKAGIPYLTHWDAGAVVLEMYEHLVEDQTTEP
Mvan_3330|M.vanbaalenii_PYR-1       LGEQIGPDTDLATLRLLCDRAGIPYLTHWDAGAVVLELYEHLVEDQTREP
MSMEG_3796|M.smegmatis_MC2_155      IGEHITPETELGELRRLCDSAGIPYLTHWDAGAVVLEMYEHLVEDRTTEP
MLBr_01393|M.leprae_Br4923          LGECVDTSTELATLRKLSDAAHIPYWPHWDTGAVVLKLYEHLVENRTDQP
                                                                                      

Rv1619|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1645|M.bovis_AF2122/97            --------------------------------------------------
MMAR_2422|M.marinum_M               --------------------------------------------------
MUL_1600|M.ulcerans_Agy99           --------------------------------------------------
MAV_3168|M.avium_104                --------------------------------------------------
MAB_2636c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_3544|M.gilvum_PYR-GCK          TFYKDFPTSVSPLTRPHRSIPGVAERWDLVAWGVELGTAYSELTDPVEQR
Mvan_3330|M.vanbaalenii_PYR-1       TFYKDFPTSVSPLTRPHRSIPGVAERWDLVAWGVELGTAYSELTDPVEQR
MSMEG_3796|M.smegmatis_MC2_155      TFYKDFPTSVSPLTRPHRSIPGVAERWDLVAWGVELGTAYSELTDPVEQR
MLBr_01393|M.leprae_Br4923          TFYIDFPTSVSPLTRPHRSKPGVAERWDLVAWGIELGTAYSELTDPVEQR
                                                                                      

Rv1619|M.tuberculosis_H37Rv         --------------------------------------------------
Mb1645|M.bovis_AF2122/97            --------------------------------------------------
MMAR_2422|M.marinum_M               --------------------------------------------------
MUL_1600|M.ulcerans_Agy99           --------------------------------------------------
MAV_3168|M.avium_104                --------------------------------------------------
MAB_2636c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_3544|M.gilvum_PYR-GCK          RRLQEQSLLAAGGDPEAMELDEDFLQAMEYAMPPTGGLGMGVDRVVMLIT
Mvan_3330|M.vanbaalenii_PYR-1       RRLQEQSLLAAGGDPEAMELDEDFLQAMEYAMPPTGGLGMGVDRVVMLIT
MSMEG_3796|M.smegmatis_MC2_155      RRLQEQSLLAAGGDPEAMELDEDFLQAMEYAMPPTGGLGMGVDRVVMMIT
MLBr_01393|M.leprae_Br4923          RRLHEQSLLAVGGNPEAMELDEDFLQAMEYAMPPTGGLGMGIDRLVMLIT
                                                                                      

Rv1619|M.tuberculosis_H37Rv         ----------------
Mb1645|M.bovis_AF2122/97            ----------------
MMAR_2422|M.marinum_M               ----------------
MUL_1600|M.ulcerans_Agy99           ----------------
MAV_3168|M.avium_104                ----------------
MAB_2636c|M.abscessus_ATCC_199      ----------------
Mflv_3544|M.gilvum_PYR-GCK          GRSIRETLPFPLAKPR
Mvan_3330|M.vanbaalenii_PYR-1       GRSIRETLPFPLAKPR
MSMEG_3796|M.smegmatis_MC2_155      GRSIRETLPFPLAKPR
MLBr_01393|M.leprae_Br4923          GRSIRETLPFPLAKPH