For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. tuberculosis H37Rv Rv1576c (-)

TEFDDIKNLSLPETRDAAKQLLDSVAGDLTGEAAQRFQALTRHAEELRAEQRRRGREAEEALRRYRAGEL
RVVPGAPTGGDDGDAPPGNSLRDTAFRTLDSCVRDGLMSSRAAETAETLCRTGPPQSTSWAQRWLAATGS
RDYLGAFVKRVSNPVAGHTVWTDREAAAWREAAAVAAEQRAMGLVDTQGGFLIPAALDPAILLSGDGSTN
PIRQVARVVQTTSEIWRGVTSEGAEARWYSEAQEVSDDSPALAQPAVPNYRGSCWIPFSIELEGDAASFV
GEIGKILADSVEQLQAAAFVNGSGNGEPTGFVSALTGTSDQVVVGAGSEAIVAADVYALQSALPPRFQAS
AAFAANLSTINTLRQAETSNGALKFPSLHDSPPMLAGKSVLEVSHMDTVDSAVTATNHPLVLGDWKQFLI
GDRVGSMVELVPHLFGPNRRPTGQRGFFAWFRVGSDVLVRNAFRVLKVETTA*

Operon Prediction Model: Genebank

Paralogs

species	id	gene	e-value	identity (len)	annotation
M. tuberculosis H37Rv	Rv1576c	-	-	100% (473)	Probable phiRV1 phage protein
M. tuberculosis H37Rv	Rv2650c	-	0.0	89.10% (468)	phiRv2 prophage protein

Closest Orthologs (e-value cutoff: 1e-4)

species	id	gene	e-value	identity (len)	annotation
M. bovis AF2122 / 97	Mb1602c	-	0.0	99.37% (473)	phiRV1 phage protein
M. gilvum PYR-GCK	-	-	-	-	-
M. leprae Br4923	-	-	-	-	-
M. abscessus ATCC 19977	-	-	-	-	-
M. marinum M	-	-	-	-	-
M. avium 104	-	-	-	-	-
M. smegmatis MC2 155	-	-	-	-	-
M. thermoresistible (build 8)	-	-	-	-	-
M. ulcerans Agy99	-	-	-	-	-
M. vanbaalenii PYR-1	Mvan_4361	-	1e-64	41.49% (335)	phage major capsid protein, HK97

CLUSTAL 2.0.9 multiple sequence alignment


Rv1576c|M.tuberculosis_H37Rv       MTEFDDIKNLSLPETRDAAKQLLDSVAGDLTGEAAQRFQALTRHAEELRA
Mb1602c|M.bovis_AF2122/97          MTEFDDIKNLSLPETRDAAKQLLDSVAGDLTGEAAQRFQALTRHAEELRA
Mvan_4361|M.vanbaalenii_PYR-1      ---------------------------------------MTTRIVDDPWD
                                                                            ** .::   

Rv1576c|M.tuberculosis_H37Rv       EQRRRGREAEEALRRYRAGELRVVPGAPTGGDDGDAPPGNSLRDTAFRTL
Mb1602c|M.bovis_AF2122/97          EQRRRGREAEEELRRYRAGELRVVPGAPTGGDDGDAPPGNSLRDTAFRTL
Mvan_4361|M.vanbaalenii_PYR-1      TTQIRG-SGDDYVTQMRSHACAAIEKMPFADDK--------VREVATRFV
                                     : ** ..:: : : *:    .:   * ..*.        :*:.* * :

Rv1576c|M.tuberculosis_H37Rv       DSCVRDGLMSSRAAETAETLCRTGPPQSTSWAQRWLAATGSRDYLGAFVK
Mb1602c|M.bovis_AF2122/97          DSCVRDGLMSSRAAETAETLCRTGPPQSTSWAQRWLAATGSRDYLGAFVK
Mvan_4361|M.vanbaalenii_PYR-1      E---RDGEEHAPVAN-------------------LVLATTSPDYSRAFTK
                                   :   ***   : .*:                    : ** * **  **.*

Rv1576c|M.tuberculosis_H37Rv       RVSNPVAGHTVWTDREAAAWREAAAVAAEQRAMGLVDTQGGFLIPAALDP
Mb1602c|M.bovis_AF2122/97          RVSNPVAGHTVWTDREAAAWREAAAVAAEQRAMGLVDTQGGFLIPAALDP
Mvan_4361|M.vanbaalenii_PYR-1      MIR-SRGNPTVLSGREVQAY---------QRAMSLTDNQGGFLVPMQLDP
                                    :  . .. ** :.**. *:         ****.*.*.*****:*  ***

Rv1576c|M.tuberculosis_H37Rv       AILLSGDGSTNPIRQVARVVQTTSEIWRGVTSEGAEARWYSEAQEVSDDS
Mb1602c|M.bovis_AF2122/97          AILLSGDGSTNPIRQVARVVQTTSEIWRGVTSEGAEARWYSEAQEVSDDS
Mvan_4361|M.vanbaalenii_PYR-1      TIILTANGSFNQVRQISRVVQATGKSWTGVTSAGVSGSWDGEAVEVSDDS
                                   :*:*:.:** * :**::****:*.: * **** *... * .** ******

Rv1576c|M.tuberculosis_H37Rv       PALAQPAVPNYRGSCWIPFSIELEGDAASFVGEIGKILADSVEQLQAAAF
Mb1602c|M.bovis_AF2122/97          PALAQPAVPNYRGSCWIPFSIELEGDAASFVGEIGKILADSVEQLQTAAF
Mvan_4361|M.vanbaalenii_PYR-1      PELQQPEIPVHKLQIWVEFSHELQHDAAGLADDIAKMIAFEKDVKESIAF
                                   * * ** :* :: . *: ** **: ***.:..:*.*::* . :  :: **

Rv1576c|M.tuberculosis_H37Rv       VNGSGNGEPTGFVSALTGTSDQVVVGAGSEAIVAADVYALQSALPPRFQA
Mb1602c|M.bovis_AF2122/97          VNGSGNGEPTGFVSALTGTSDQVVVGAGSEAIVAADVYALQSALPPRFQA
Mvan_4361|M.vanbaalenii_PYR-1      ATGSGVGQPRGVITALMG-SDSVVNSAVTDTFAAGDVHNLDGDLPQRYAF
                                   ..*** *:* *.::** * **.** .* ::::.*.**: *:. ** *:  

Rv1576c|M.tuberculosis_H37Rv       SAAFAANLSTINTLRQAETSNGALKFPSLHDS-PPMLAGKSVLEVSHMDT
Mb1602c|M.bovis_AF2122/97          SAAFAANLSTINTLRQAETSNGALKFPSLHDS-PPMLAGKSVLEVSHMDT
Mvan_4361|M.vanbaalenii_PYR-1      NASWLAHRKIYSKIRQFDTNGGASLWGQLAEGRKSELLGRPDYVAEAMDS
                                   .*:: *: .  ..:** :*..**  : .* :.  . * *:.   .. **:

Rv1576c|M.tuberculosis_H37Rv       VDSAVTATNHPLVLGDWKQFLIGDRVGSMVELVPHLFGPNRRPTGQRGFF
Mb1602c|M.bovis_AF2122/97          VDSAVTATNHPLVLGDWKQFLIVDRVGSMVELVPHLFGPNRRPTGQRGFF
Mvan_4361|M.vanbaalenii_PYR-1      SITNG-QDNHVLAFGDFQNFVIADRLGTTLSYIPNLMGPNGRPVGKAGWH
                                     :     ** *.:**:::*:* **:*: :. :*:*:*** **.*: *:.

Rv1576c|M.tuberculosis_H37Rv       AWFRVGSDVLVRNAFRVLKVETTA
Mb1602c|M.bovis_AF2122/97          AWFRVGSDVLVRNAFRVLKVETTA
Mvan_4361|M.vanbaalenii_PYR-1      AWIRVGSDVVNPGAFRLLNVT---
                                   **:******:  .***:*:*