For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MYERRHERGMCDRAVEMTDVGATAAPTGPIARGSVARVGAATALAVACVYTVIYLAARDLPPACFSIFAV FWGALGIATGATHGLLQETTREVRWVRSTQIVAGHRTHPLRVAGMIGTVAAVVIAGSSPLWSRQLFVEGR WLSVGLLSVGVAGFCAQATLLGALAGVDRWTQYGSLMVTDAVIRLAVAAAAVVIGWGLAGYLWAATAGAV AWLLMLMASPTARSAASLLTPGGIATFVRGAAHSITAAGASAILVMGFPVLLKVTSDQLGAKGGAVILAV TLTRAPLLVPLSAMQGNLIAHFVDRRTQRLRALIAPALVVGGIGAVGMLAAGLTGPWLLRVGFGPDYQTG GALLAWLTAAAVAIAMLTLTGAAAVAAALHRAYLLGWVSATVASTLLLLLPMPLETRTVIALLFGPTVGI AIHVAALARRPD
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1510 | - | - | 100% (432) | conserved probable membrane protein |
| M. tuberculosis H37Rv | Rv3630 | - | e-168 | 70.75% (424) | integral membrane protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3654 | - | 1e-169 | 70.99% (424) | integral membrane protein |
| M. gilvum PYR-GCK | Mflv_1402 | - | 1e-146 | 63.26% (411) | putative integral membrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0508c | - | 1e-131 | 60.40% (404) | hypothetical protein MAB_0508c |
| M. marinum M | MMAR_5130 | - | 1e-170 | 73.17% (410) | hypothetical protein MMAR_5130 |
| M. avium 104 | MAV_0526 | - | 1e-167 | 71.91% (413) | hypothetical protein MAV_0526 |
| M. smegmatis MC2 155 | MSMEG_6140 | - | 1e-156 | 68.72% (422) | membrane protein |
| M. thermoresistible (build 8) | TH_0619 | - | 1e-151 | 67.08% (401) | PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN |
| M. ulcerans Agy99 | MUL_4207 | - | 1e-165 | 72.98% (396) | hypothetical protein MUL_4207 |
| M. vanbaalenii PYR-1 | Mvan_5388 | - | 1e-154 | 67.65% (408) | putative integral membrane protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1402|M.gilvum_PYR-GCK ------------------MTDATAGPSGAVSRASVVRVGVATALSALCGY
Mvan_5388|M.vanbaalenii_PYR-1 ------------------MTDATAGPSGAVTRGSVVRVGAATAMSAMCGY
MMAR_5130|M.marinum_M ---------MTEVGGTT---GAAGASGGAIARGSVARVGTATAVTALCGY
MUL_4207|M.ulcerans_Agy99 ----------------------------------MARVGTATAVTALCGY
Mb3654|M.bovis_AF2122/97 --MAVGAAAVTEVGDTASPVGSSGASGGAIASGSVARVGTATAVTALCGY
MAV_0526|M.avium_104 ---------MTEI----------SASQGPVARGSMARVGTATAVTALCGY
Rv1510|M.tuberculosis_H37Rv MYERRHERGMCDRAVEMTDVGATAAPTGPIARGSVARVGAATALAVACVY
MSMEG_6140|M.smegmatis_MC2_155 ---------MTDGGAPAP-FDPDDPARGAITRGSIARVGSATAITALCGY
TH_0619|M.thermoresistible__bu -------------------VTDATPATGAITRASVMRVGVATALSALCGY
MAB_0508c|M.abscessus_ATCC_199 -----------------------MTDAGPSTRSSVARIGAATAVSAICGY
: *:* ***::. * *
Mflv_1402|M.gilvum_PYR-GCK AVLYLAARDLEPAGFSVFGVFWGAFGLVSGAAFGLLQETTREVRHPSAGT
Mvan_5388|M.vanbaalenii_PYR-1 AVLYLAARDLEPAGFSVFGVFWGAFGLASGAAFGLLQETTREVRAPSWNP
MMAR_5130|M.marinum_M TVIYLAARDLAPSGFSVFGVFWGAFGLVSGAANGLLQEATREVRSAQYLD
MUL_4207|M.ulcerans_Agy99 TVIYLAARDLAPSGFSVFGVFWGAFGLVSGTANGLLQEATREVRSAQYLD
Mb3654|M.bovis_AF2122/97 AVIYLAARNLAPNGFSVFGVFWGAFGLVTGAANGLLQETTREVRSLGYLD
MAV_0526|M.avium_104 AVIYLAARDLAPSGFSVFGVFWGAFGLVTGAANGLLQETTREVRVMPYLE
Rv1510|M.tuberculosis_H37Rv TVIYLAARDLPPACFSIFAVFWGALGIATGATHGLLQETTREVRWVRSTQ
MSMEG_6140|M.smegmatis_MC2_155 AVLYLAARDLEPAGFSVFAVFWGAFGLVTGAANGLLQEATREVRSVQVAP
TH_0619|M.thermoresistible__bu AVMYLAARDLAPEGFSVFSVFWGAFGLVTGAANGLLQEATREVRSVRHTP
MAB_0508c|M.abscessus_ATCC_199 AVLYLAARELGPALFSVFGVFWGAFGLVTGAANGLLQETTREVRLSLAQR
:*:*****:* * **:*.*****:*:.:*:: *****:*****
Mflv_1402|M.gilvum_PYR-GCK AHRH-----TRPLAVAAAVGVAAAAAIGVSAPLWSAHVFVDARMLSVALL
Mvan_5388|M.vanbaalenii_PYR-1 DGTY-----TRPMRVAAGVGVGAAAVIAVTSPLWSGHVFVDARGLSVALL
MMAR_5130|M.marinum_M VVPE--GGRTHPLRIAGMVGLASAVVIAGSSPLWSGRVFVEDRWLSVGLL
MUL_4207|M.ulcerans_Agy99 VVPE--GGRTHPLRIAGMVGLASAVVIAGSSPLWSGRVFVEDRWLSVGLL
Mb3654|M.bovis_AF2122/97 VSAD--GRRTHPLRVSGMVGLGSLVVIAGSSPLWSGRVFAEARWLSVALL
MAV_0526|M.avium_104 VAP---VKRTHPLRVAMLLGAAAAVVIAGSSPLWSGRVFVEARPLSVLLL
Rv1510|M.tuberculosis_H37Rv IVA---GHRTHPLRVAGMIGTVAAVVIAGSSPLWSRQLFVEGRWLSVGLL
MSMEG_6140|M.smegmatis_MC2_155 RVSGVSGPRTNPMRVAAAVGVVAALVIAGTSPLWSGHVFVESRALSVALL
TH_0619|M.thermoresistible__bu DPAV---RRTRPMLIATLVAGLAAAAIVGTAPVWAGHVFAEARPLSVLLL
MAB_0508c|M.abscessus_ATCC_199 DRSP--LATTLPVRIASAFAIASAVLIVGTAPLWASHVFTEFRWLSVALL
* *: :: .. : * ::*:*: ::*.: * *** **
Mflv_1402|M.gilvum_PYR-GCK CAGLAGFCVHTTLLGALAGMGRWSDYGALMVTDAALRVVVAAAGFAAGWG
Mvan_5388|M.vanbaalenii_PYR-1 SAGLAGFCLHTTLLGALAGMNRWSEYGALMVTDAVLRVVVAAATFALAWG
MMAR_5130|M.marinum_M SVGLAGFCLHATLLGMLAGTNRWSHYGSLMVTDAIIRVAVSAATFAIGWG
MUL_4207|M.ulcerans_Agy99 SVGLAGFCLHATLLGMLAGTNRWSHYGSLMVTDAIIRVAVSAATFAIGWG
Mb3654|M.bovis_AF2122/97 SIGLAGFCLHATLLGMLAGTNRWTQYGALMVADAVIRVVVAAATFVIGWQ
MAV_0526|M.avium_104 SVGLAGFCVHATLLGMLAGTNEWTRYGALMVTDAVIRVMVAAATVVLGWR
Rv1510|M.tuberculosis_H37Rv SVGVAGFCAQATLLGALAGVDRWTQYGSLMVTDAVIRLAVAAAAVVIGWG
MSMEG_6140|M.smegmatis_MC2_155 SVGLAGFCLHATLLGMLAGIDRWTEYGALMVTDAGIRVGVAAASFVLGWG
TH_0619|M.thermoresistible__bu AAGVAGFCLHATLLGMLAGVNRWTQYGSLMVTDAAIRVVVAAATFAVGWG
MAB_0508c|M.abscessus_ATCC_199 AGGLAGFCMHATTLGALAGSSRWTQYGVLMVTDAGIRLVVAIVTFAATLG
. *:**** ::* ** *** ..*: ** ***:** :*: *: . ..
Mflv_1402|M.gilvum_PYR-GCK LGGYLWATVAGAFSWLLMLLVSPATRAAARVQTTGGTATFLRGAGHSMAA
Mvan_5388|M.vanbaalenii_PYR-1 LGGYLWATVAGSTAWLLMMLVSPATRAAARLLTPGGTATFLRGAGHSIAA
MMAR_5130|M.marinum_M LVGFLWATVAGSVSWLILLLASPVARATARLLTPGNTATFLRGAAHSITA
MUL_4207|M.ulcerans_Agy99 LVGFLWATVAGSVSWLILLLASPVARATARLLTPGNTATFLRGAAHSITA
Mb3654|M.bovis_AF2122/97 LVGFIWATVAGSVAWLIMLMTSPPTRAAARLMTPGATATFLRGAAHSIIA
MAV_0526|M.avium_104 LVGFLWATVAGAVAWLILLAASPATRATARLLTPGGTATFLRGAAHSITA
Rv1510|M.tuberculosis_H37Rv LAGYLWAATAGAVAWLLMLMASPTARSAASLLTPGGIATFVRGAAHSITA
MSMEG_6140|M.smegmatis_MC2_155 LGGYLWATVAGAGAWLILLLTAPAARVAARQVTAGGTWTFVRGTAHSIAA
TH_0619|M.thermoresistible__bu LVGFLWATVAGAVAWLLMLLVSPSARQAARVRTAGGTVAFLRGASHSIAA
MAB_0508c|M.abscessus_ATCC_199 LVGYLWATVSGSMSWLLLTLVSKPTRDALKVPALVDTMEFLRGARHSIAA
* *::**:.:*: :**:: .: :* : : *:**: **: *
Mflv_1402|M.gilvum_PYR-GCK AGASAVLVMGFPVLLAATSGDLGATGGVVILAVTLTRAPLMVPLTAMQGN
Mvan_5388|M.vanbaalenii_PYR-1 AGASAVLVMGFPVLLKATSGDLGAAGGVVILAVTLTRAPLLVPLTAMQGN
MMAR_5130|M.marinum_M AGASAILVMGFPVLLKLTSNELGPQGGVIILAVTLTRAPLLVPLTAMQGN
MUL_4207|M.ulcerans_Agy99 AGASAILVMGFPVLLKLTSNELGPQGGVIILAVTLTRAPLLVPLTAMQGN
Mb3654|M.bovis_AF2122/97 AGASAILVMGFPVLLKLTSNELGAQGGVVILAVTLTRAPLLVPLTAMQGN
MAV_0526|M.avium_104 AGASAILVMGFPVLLKLTSAELGAQGGVIILAVTLTRAPLLVPLTAMQGN
Rv1510|M.tuberculosis_H37Rv AGASAILVMGFPVLLKVTSDQLGAKGGAVILAVTLTRAPLLVPLSAMQGN
MSMEG_6140|M.smegmatis_MC2_155 AGASAILVMGFPVLLKATSADLGAAGGVVILAVTLTRAPLLVPLTAMQGN
TH_0619|M.thermoresistible__bu AGASAVLVTGFPVLLKATYGDLGAAGGVVILAVMLTRAPLLIPLTAMQGN
MAB_0508c|M.abscessus_ATCC_199 AAASAVLVMGFPVLLQSTAGDLGTTGGVVILAVTLTRAPLLVPLTALQGN
*.***:** ****** * :**. **.:**** ******::**:*:***
Mflv_1402|M.gilvum_PYR-GCK LIAYFIDQRAHRLKALLAPSALVAALGAGGVVLAAVFGPWLLREAFGAQY
Mvan_5388|M.vanbaalenii_PYR-1 LIAHFVDQREHRLKALVAPAALVGALGAAGVALAAAFGPWLLREAFGAQY
MMAR_5130|M.marinum_M LIAHFVDESAQRLRALISPAALIGGIGVIGVLAAGAVGPWLLRSAFGQQY
MUL_4207|M.ulcerans_Agy99 LIAHFVDESAQRLRALISPAALIGGIGVIGVLAAGAVGPWLLRSAFGQQY
Mb3654|M.bovis_AF2122/97 LIAHFVDERTERIRALIAPAALIGGVGAVGMLAAGVVGPWIMRVAFGSEY
MAV_0526|M.avium_104 LIAHFVDERSDRVRALIGPAAIVGAIGAVGVLAAGVLGPWVLRVAFGPQY
Rv1510|M.tuberculosis_H37Rv LIAHFVDRRTQRLRALIAPALVVGGIGAVGMLAAGLTGPWLLRVGFGPDY
MSMEG_6140|M.smegmatis_MC2_155 LIAHFVDQ--ARLRALLMPAAVVAVIGAAGVVAAGLIGPWLLKVGFGDEY
TH_0619|M.thermoresistible__bu LIAHFVDERARRLRALVAPVGVVVTVGAVGVVGAGLVGPWLLRVAFGPDY
MAB_0508c|M.abscessus_ATCC_199 LIAHFVDEQDRRLRALATPAAIILGVGAAGIALAASIGPWLLRTVFDPAY
***:*:*. *::** * :: :*. *: *. ***::: *. *
Mflv_1402|M.gilvum_PYR-GCK RAEGALLAWLTVAAVAIALLTLTGAATVAAALHRAYAAGWVIATAAAALL
Mvan_5388|M.vanbaalenii_PYR-1 HADGTLLGWLTAAAVAIALLTLTGAATVAAALHRAYAAGWVIATVAATLL
MMAR_5130|M.marinum_M QASGALLAWLTAAAVAIAMLTLTGAAAVAAALHRAYSLGWVSATAASGLL
MUL_4207|M.ulcerans_Agy99 QASGSLLAWLTAAAVAIAMLTLTGAAAVAAALHRAYSLGWVSATAASGLL
Mb3654|M.bovis_AF2122/97 QSSSALLAWLTAAAVAIAMLTLTGAAAVAAALHRAYSLGWVGATVGSGLL
MAV_0526|M.avium_104 QAGSALLAWLTAAAVAIAMLTLTGAAAVAAALHRAYALGWVGATVASGLL
Rv1510|M.tuberculosis_H37Rv QTGGALLAWLTAAAVAIAMLTLTGAAAVAAALHRAYLLGWVSATVASTLL
MSMEG_6140|M.smegmatis_MC2_155 RADGTLLAWLTAAAVAIAMLTLTGAAAVAAALHRTYALGWIIATVAAVGL
TH_0619|M.thermoresistible__bu VADGSVLAWLTAAATSIAVLTVTGAATVAAALHRAYAVGWVSATVASTLL
MAB_0508c|M.abscessus_ATCC_199 QAGGPLLGWLTAGAVMIALLTLTGAATVAHARHRAYSAGWVGATVVSALL
: ..:*.***..*. **:**:****:** * **:* **: **. : *
Mflv_1402|M.gilvum_PYR-GCK LMLPLDLEVRAVVALLCGPLLGIAVHLSALARD----RDGVAPTYAAIDD
Mvan_5388|M.vanbaalenii_PYR-1 LLLPLDLEVRTVVALLCGPLLGIAVHLSALARA----RSIRWHTPAPSDT
MMAR_5130|M.marinum_M LLLPLPLEARTVVALLCGPLVGIGVHLLALA------RAGYASR------
MUL_4207|M.ulcerans_Agy99 LLLPLPLEARTVVALLCGPLVGIGVHLLALA------RAGYASR------
Mb3654|M.bovis_AF2122/97 LLLPLSLETRTVVALLCGPLVGIGVHLVALA------RTDE---------
MAV_0526|M.avium_104 LALPLSLQTRTVVGLLCGPLVGIGVHLVALS------RAARLTG------
Rv1510|M.tuberculosis_H37Rv LLLPMPLETRTVIALLFGPTVGIAIHVAALA------RRPD---------
MSMEG_6140|M.smegmatis_MC2_155 LLLPLELSTRTVVALLCGPLVGIAVHLVGLA------RFSRVSG------
TH_0619|M.thermoresistible__bu LLVPSALETRAVVALLCGPLVGIGVHLLALLGHGPDRRAGTAANTLPT--
MAB_0508c|M.abscessus_ATCC_199 LLLPLGLEERTVIALLGGPVVGIVVHLIALAFW----RDPQLAEDIFD--
* :* *. *:*:.** ** :** :*: .* *
Mflv_1402|M.gilvum_PYR-GCK ----
Mvan_5388|M.vanbaalenii_PYR-1 KETP
MMAR_5130|M.marinum_M ----
MUL_4207|M.ulcerans_Agy99 ----
Mb3654|M.bovis_AF2122/97 ----
MAV_0526|M.avium_104 ----
Rv1510|M.tuberculosis_H37Rv ----
MSMEG_6140|M.smegmatis_MC2_155 ----
TH_0619|M.thermoresistible__bu ----
MAB_0508c|M.abscessus_ATCC_199 ----