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KPAHAAASWRNPLRDKRDKRLPRIAGPCGMVIFGVTGDLARKKVMPAVYDLANRGLLPPTFSLVGFARRD WSTQDFGQVVYNAVQEHCRTPFRQQNWDRLAEGFRFVPGTFDDDDAFAQLAETLEKLDAERGTGGNHAFY LAIPPKSFPVVCEQLHKSGLARPQGDRWSRVVIEKPFGHDLASARELNKAVNAVFPEEAVFRIDHYLGKE TVQNILALRFANQLFDPIWNAHYVDHVQITMAEDIGLGGRAGYYDGIGAARDVIQNHLMQLLALTAMEEP VSFHPAALQAEKIKVLSATRLAEPLDQTTSRGQYAAGWQGGEKVVGLLDEEGFAEDSTTETFAAITLEVD TRRWAGVPFYLRTGKRLGRRVTEIALVFRRAPHLPFDATMTDELGTNAMVIRVQPDEGVTLRFGSKVPGT AMEVRDVNMDFSYGSAFAEDSPEAYERLILDVLLGEPSLFPVNAEVELAWEILDPALEHWAAHGTPDAYE AGTWGPESSLEMLRRTGREWRRP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1447c | zwf2 | - | 100% (514) | glucose-6-phosphate 1-dehydrogenase |
| M. tuberculosis H37Rv | Rv1121 | zwf1 | 8e-76 | 37.32% (485) | glucose-6-phosphate 1-dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1482c | zwf2 | 0.0 | 100.00% (514) | glucose-6-phosphate 1-dehydrogenase |
| M. gilvum PYR-GCK | Mflv_3694 | - | 0.0 | 82.12% (509) | glucose-6-phosphate 1-dehydrogenase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2761 | - | 0.0 | 82.50% (503) | glucose-6-phosphate 1-dehydrogenase |
| M. marinum M | MMAR_2252 | zwf2 | 0.0 | 89.94% (517) | glucose-6-phosphate 1-dehydrogenase Zwf2 |
| M. avium 104 | MAV_3329 | zwf | 0.0 | 90.62% (512) | glucose-6-phosphate 1-dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_3101 | zwf | 0.0 | 84.98% (506) | glucose-6-phosphate 1-dehydrogenase |
| M. thermoresistible (build 8) | TH_0337 | zwf2 | 0.0 | 86.44% (509) | PROBABLE GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE ZWF2 (G6PD) |
| M. ulcerans Agy99 | MUL_1842 | zwf2 | 0.0 | 89.56% (517) | glucose-6-phosphate 1-dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_2718 | - | 0.0 | 82.81% (506) | glucose-6-phosphate 1-dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
Rv1447c|M.tuberculosis_H37Rv MKPAHA-----------AASWRNPLRDKRDKRLPRIAGPCGMVIFGVTGD
Mb1482c|M.bovis_AF2122/97 MKPAHA-----------AASWRNPLRDKRDKRLPRIAGPCGMVIFGVTGD
MAV_3329|M.avium_104 MSPART-----------AQQWHNPLRDKRDKRLPRIAGPCGMVIFGVTGD
MMAR_2252|M.marinum_M MSPPHSE--------SGVAQWQNPLRDKLDKRLPRIAGSCGMVIFGVTGD
MUL_1842|M.ulcerans_Agy99 MSPPHSE--------SGVAQWQNPLRDKLDKRLPRIAGSCGMVIFGVTGD
Mflv_3694|M.gilvum_PYR-GCK MTEP----------------WRNPLRDKRDKRMPRIAGPCSVIIFGVTGD
Mvan_2718|M.vanbaalenii_PYR-1 MPES----------------WRNPLRDKRDKRMPRIAGPCSVVIFGVTGD
TH_0337|M.thermoresistible__bu MTDPAGFGPVAGLAEPAPPGWRNPLRDKRDKRMPRIAGPCSMVIFGVTGD
MSMEG_3101|M.smegmatis_MC2_155 MTAVN---------DRPDTTWHNPLRDKRDKRMPRIAGPCGVVIFGVTGD
MAB_2761|M.abscessus_ATCC_1997 MTEVLPP---------DSSLTANPLRDKRDKRLPRIAGPCSLVIFGVTGD
* ****** ***:*****.*.::*******
Rv1447c|M.tuberculosis_H37Rv LARKKVMPAVYDLANRGLLPPTFSLVGFARRDWSTQDFGQVVYNAVQEHC
Mb1482c|M.bovis_AF2122/97 LARKKVMPAVYDLANRGLLPPTFSLVGFARRDWSTQDFGQVVYNAVQEHC
MAV_3329|M.avium_104 LARKKVMPAIYDLANRGLLPPSFSLVGFARRDWSTQDFGKVVYEAVKEHC
MMAR_2252|M.marinum_M LARKKVMPAIYDLANRGLLPPTFALVGFARRDWDTEDFGQVVYQAVKEHC
MUL_1842|M.ulcerans_Agy99 LARKKVMPAIYDLANRGLLPPTFALVGFARRDWDTEDFGQVVYQAVKEHC
Mflv_3694|M.gilvum_PYR-GCK LARKKLMPAIYDLANRGLLPPSFALVGFARRDWADEDFGQVVYEAVKKHA
Mvan_2718|M.vanbaalenii_PYR-1 LARKKLMPAIYDLANRGLLPPSFALVGFARRDWADEDFGEVVYEAVKKHA
TH_0337|M.thermoresistible__bu LSRKKLMPAIYDLANRGLLPASFSLVGFARRDWADEDFGQVVYEAVKTHA
MSMEG_3101|M.smegmatis_MC2_155 LARKKLMPAIYDLANRGLLPASFALVGFARRDWEDEDFGQVVYDAVRQHA
MAB_2761|M.abscessus_ATCC_1997 LARKKLMPAIYDLANRGLLPPSFALVGFARRDWANEDFGQIVLDAVKAHS
*:***:***:**********.:*:********* :***::* :**: *.
Rv1447c|M.tuberculosis_H37Rv RTPFRQQNWDRLAEGFRFVPGTFDDDDAFAQLAETLEKLDAERGTGGNHA
Mb1482c|M.bovis_AF2122/97 RTPFRQQNWDRLAEGFRFVPGTFDDDDAFAQLAETLEKLDAERGTGGNHA
MAV_3329|M.avium_104 RTPFRQENWDRLAEGFRFVPGAFDDDEAFGRLAETLDKLDAERGTGGNHA
MMAR_2252|M.marinum_M RTPFRQANWDRLAEGFRFVSGSFDDDEAFGRLAETLEKLDTERGTGGNHA
MUL_1842|M.ulcerans_Agy99 RTPFRQANWDRLAEGFRFVSGSFDDDEAFGRLAETLEKLDTERGTGGNHA
Mflv_3694|M.gilvum_PYR-GCK RTPFRQEVWDRLAEGFRFVQGTFDDDDSFARLAETLNTLDVERGTGGNHA
Mvan_2718|M.vanbaalenii_PYR-1 RTPFRQEVWDRLAEGFRFVQGTFDDDASFDRLSETLEKLDAERGTGGNHA
TH_0337|M.thermoresistible__bu RTPFRQEVWDRLAEGFRFVQGTFDDDAAFARLTEVLEKLDVQRGTGGNHA
MSMEG_3101|M.smegmatis_MC2_155 RTPFRQEVWDRLAEGIRFVQGTFDDDTAFTRLAETLDKLDIERGTGGNHA
MAB_2761|M.abscessus_ATCC_1997 RTPFRQHVWDRLAEGIRFVQGSFDDDAAFEQLKKTLQTLDEERGTGGNHG
****** *******:*** *:**** :* :* :.*:.** :*******.
Rv1447c|M.tuberculosis_H37Rv FYLAIPPKSFPVVCEQLHKSGLARPQGDRWSRVVIEKPFGHDLASARELN
Mb1482c|M.bovis_AF2122/97 FYLAIPPKSFPVVCEQLHKSGLARPQGDRWSRVVIEKPFGHDLASARELN
MAV_3329|M.avium_104 FYLAIPPKSFPVVCEQLHKSGLARPQGDRWSRVVIEKPFGHDLESAQSLN
MMAR_2252|M.marinum_M FYLAIPPKSFPVVCGQLHKSGLARPQGDRWSRVVIEKPFGHDLQSARDLN
MUL_1842|M.ulcerans_Agy99 FYLAIPPKSFPVVCGQLHKSGLARPQGDRWSRVVIEKPFGHDLQSARDLN
Mflv_3694|M.gilvum_PYR-GCK FYLSIPPNAFPVVCEQLQKSGLARQKDHSWSRVVIEKPFGHDLDSARELN
Mvan_2718|M.vanbaalenii_PYR-1 FYLSIPPNAFPVVCEQLQRSGLARQKDHSWSRVVIEKPFGHDLASARELN
TH_0337|M.thermoresistible__bu FYLSIPPKAFPLVCEQLRRSGLARPQPGRWSRVVVEKPFGHDLQSAVELN
MSMEG_3101|M.smegmatis_MC2_155 FYLSIPPNAFPVVCEQLRKSGLAKPRDGRWSRVVIEKPFGHDLGSARELN
MAB_2761|M.abscessus_ATCC_1997 FYLSIPPNAFPTVCEQLSKSGLAQPVDGAWRRVVIEKPFGHDLASARELN
***:***::** ** ** :****: * ***:******** ** .**
Rv1447c|M.tuberculosis_H37Rv KAVNAVFPEEAVFRIDHYLGKETVQNILALRFANQLFDPIWNAHYVDHVQ
Mb1482c|M.bovis_AF2122/97 KAVNAVFPEEAVFRIDHYLGKETVQNILALRFANQLFDPIWNAHYVDHVQ
MAV_3329|M.avium_104 KAVNAVFPEESVFRIDHYLGKETVRNILALRFANQLFDPIWNSHYVDHVQ
MMAR_2252|M.marinum_M RAVNAVFPEESVFRIDHYLGKETVQNILALRFANQLFDPIWNAHYVDHVQ
MUL_1842|M.ulcerans_Agy99 RAVNAVFPEESVFRIDHYLGKETVQNILALRFANQLFDPIWNAHYVDHVQ
Mflv_3694|M.gilvum_PYR-GCK NVVNSVFPEESVFRIDHYLGKETVQNILALRFANELYEPIWNSHYVDHVQ
Mvan_2718|M.vanbaalenii_PYR-1 AVVNSVFPEESVFRIDHYLGKETVQNILALRFANELYEPVWNAHYVDHVQ
TH_0337|M.thermoresistible__bu AVVNSVFPEESVFRIDHYLGKETVQNILALRFANELYEPIWNNHYVDHVQ
MSMEG_3101|M.smegmatis_MC2_155 SVVNSVFPEESVFRIDHYLGKETVQNILALRFANALYEPIWNNNYVDHVQ
MAB_2761|M.abscessus_ATCC_1997 AVVNEVFPEESVFRIDHYLGKETVQNILALRFANQLFDPIWNAHFVDHVQ
.** *****:*************:********* *::*:** ::*****
Rv1447c|M.tuberculosis_H37Rv ITMAEDIGLGGRAGYYDGIGAARDVIQNHLMQLLALTAMEEPVSFHPAAL
Mb1482c|M.bovis_AF2122/97 ITMAEDIGLGGRAGYYDGIGAARDVIQNHLMQLLALTAMEEPVSFHPAAL
MAV_3329|M.avium_104 ITMAEDIGLGGRAGYYDGIGAARDVIQNHLMQLLALTAMEEPVSFSPLAL
MMAR_2252|M.marinum_M ITMAEDIGLGGRAGYYDGIGAARDVIQNHLMQLLALTAMEEPVSFNPTAL
MUL_1842|M.ulcerans_Agy99 ITMAEDIGLGGRAGYYDGIGAARDVIQNHLMQLLALTAMEEPVSFNPTAL
Mflv_3694|M.gilvum_PYR-GCK ITMAEDIGLGGRAGYYDGIGAARDVIQNHLIQLLALTAMEEPVNFSPHEL
Mvan_2718|M.vanbaalenii_PYR-1 ITMAEDIGLGGRAGYYDGIGAARDVIQNHLIQLLALTAMEEPVNFSPHEL
TH_0337|M.thermoresistible__bu ITMAEDIGLGGRAGYYDGIGAARDVIQNHLLQLLALTAMEEPVSFHPRQL
MSMEG_3101|M.smegmatis_MC2_155 ITMAEDIGLGGRAGYYDGIGAARDVIQNHLLQLLALTALEEPVSFSPHEL
MAB_2761|M.abscessus_ATCC_1997 ITMAEDIGLGGRAGYYDGIGAARDVIQNHLLQLLAFTAMEEPINFSPAEL
******************************:****:**:***:.* * *
Rv1447c|M.tuberculosis_H37Rv QAEKIKVLSATRLAEPLDQTTSRGQYAAGWQGGEKVVGLLDEEGFAEDST
Mb1482c|M.bovis_AF2122/97 QAEKIKVLSATRLAEPLDQTTSRGQYAAGWQGGEKVVGLLDEEGFAEDST
MAV_3329|M.avium_104 QAEKIKVLSATHLAHPLDETTSRGQYTAGWQGGEKVVGLLDEEGFAKDSI
MMAR_2252|M.marinum_M QTEKIKVLSATQLAEPLDETTSRGQYTAGWQGGEKVVGLLDEEGFSKTST
MUL_1842|M.ulcerans_Agy99 QTEKIKVLSATQLAEPLDETTSRGQYTTGWQGGEKVVGLLDEEGFSKTST
Mflv_3694|M.gilvum_PYR-GCK QAEKIKVLGATRPLGPLDQTTARGQYAAGWQGSERVPGLLEEDGFATDSV
Mvan_2718|M.vanbaalenii_PYR-1 QAEKIKVLSATRPLQPLDQTTARGQYAAGWQGSEKVPGLLEEGGFAHDSV
TH_0337|M.thermoresistible__bu QAEKIKVLSAVRLAQPLDQTTARGQYTAGWQGGERVVGLLEEEGFAKDST
MSMEG_3101|M.smegmatis_MC2_155 QTEKIKILSAVKLAEPLDETTARGQYAAGWQGGEKVVGLLDEEGFAKDST
MAB_2761|M.abscessus_ATCC_1997 QAEKIKVLSATRLAEPLAETTARGQYGPGWQGSQQVPGLLEEEGFSKTST
*:****:*.*.: ** :**:**** .****.::* ***:* **: *
Rv1447c|M.tuberculosis_H37Rv TETFAAITLEVDTRRWAGVPFYLRTGKRLGRRVTEIALVFRRAPHLPFDA
Mb1482c|M.bovis_AF2122/97 TETFAAITLEVDTRRWAGVPFYLRTGKRLGRRVTEIALVFRRAPHLPFDA
MAV_3329|M.avium_104 TETFAAITLEVDTRRWAGVPFYLRTGKRLGRRVTEIALVFKRAPHLPFDA
MMAR_2252|M.marinum_M TETFAAITLEVNSRRWAGVPFYLRTGKRLGRRVTEIALVFKRAPHLPFDA
MUL_1842|M.ulcerans_Agy99 TETFAAITLEVNSRRWAGVPFYLRTGKRLGRRVTEIALVFKRAPHLPFDA
Mflv_3694|M.gilvum_PYR-GCK TETFAAITLEVDTRRWAGVPFFLRTGKRLARRVTEVALVFKRAPHLPFDA
Mvan_2718|M.vanbaalenii_PYR-1 TETFAAITLEVDTRRWAGVPFFLRTGKRLPRRVTEVALVFKRAPHLPFDS
TH_0337|M.thermoresistible__bu TETFAAITLEIDTRRWAGVPFYLRTGKRLGRRVTEIALVFRRAPHLPFDA
MSMEG_3101|M.smegmatis_MC2_155 TETYAAITLEVNTRRWAGVPFYLRTGKRLGRRVTEIALVFKRAPHLPFDA
MAB_2761|M.abscessus_ATCC_1997 TETFAAITLEVDSRRWAGVPFYLRTGKRLGRRVTEIALVFKRAPHLPFDS
***:******:::********:******* *****:****:********:
Rv1447c|M.tuberculosis_H37Rv TMTDELGTNAMVIRVQPDEGVTLRFGSKVPGTAMEVRDVNMDFSYGSAFA
Mb1482c|M.bovis_AF2122/97 TMTDELGTNAMVIRVQPDEGVTLRFGSKVPGTAMEVRDVNMDFSYGSAFA
MAV_3329|M.avium_104 TMTDELGANAMVIRVQPDEGVTLRFGSKVPGTAMEVRDVNMDFSYGSAFA
MMAR_2252|M.marinum_M TMTDELGTNALVIRVQPDEGMTLRFGSKVPGSAMEVRDVNMDFSYGSAFA
MUL_1842|M.ulcerans_Agy99 TMTDELGTNALVIRVQPDEGMTLRFGSKVPGSAMEVRDVNMDFSYGSAFA
Mflv_3694|M.gilvum_PYR-GCK TMTEELGKNALVLRIQPDEGITMRFGSKVPGSAMEVRDVNMDFSYGSAFA
Mvan_2718|M.vanbaalenii_PYR-1 TMTEELGKNALVIRIQPDEGITMRFGSKVPGSAMEVRDVNMDFSYGSAFA
TH_0337|M.thermoresistible__bu TMTEELGQNALVIRIQPDEGVTLRFGSKVPGSAMEVRDVNMDFSYGSAFA
MSMEG_3101|M.smegmatis_MC2_155 TMTEELGQNALVIRVQPDEGITLRFGSKVPGSAMEVRDVNMDFSYGSAFA
MAB_2761|M.abscessus_ATCC_1997 TMTEELGANALVIRVQPDEGVTLRFGSKVPGSAMEVRDVNMDFSYEQAFT
***:*** **:*:*:*****:*:********:************* .**:
Rv1447c|M.tuberculosis_H37Rv EDSPEAYERLILDVLLGEPSLFPVNAEVELAWEILDPALEHWA----AHG
Mb1482c|M.bovis_AF2122/97 EDSPEAYERLILDVLLGEPSLFPVNAEVELAWEILDPALEHWA----AHG
MAV_3329|M.avium_104 EESPEAYEQLILDVLLGEPSLFPVNAEVELAWHILDPVLDNWA----SGG
MMAR_2252|M.marinum_M EDSPEAYERLILDVLLGEPSLFPVNAEVELAWEILDPALDNWA----SSG
MUL_1842|M.ulcerans_Agy99 EDSPEAYERLILDVLLGEPSLFPVNAEVELAWEILDPVLDNWA----SSG
Mflv_3694|M.gilvum_PYR-GCK EDSPEAYERLILDVLLGEPSLFPVNAEVELSWEILDPVLENWAQNDDASA
Mvan_2718|M.vanbaalenii_PYR-1 EDSPEAYERLILDVLLGEPSLFPVNAEVELSWEILDPVLDNWS----AQG
TH_0337|M.thermoresistible__bu EDSPEAYERLILDVLLGEPSLFPVNAEVELSWKILDPILEYWA----SHG
MSMEG_3101|M.smegmatis_MC2_155 EDSPEAYERLILDVLLGEPSLFPVNEEVELSWEILDPVLEYWA----QHG
MAB_2761|M.abscessus_ATCC_1997 EESPEAYERLILDVLLGEPSLFPVNAEVELSWRILDPALDFWA----SQG
*:******:**************** ****:*.**** *: *: .
Rv1447c|M.tuberculosis_H37Rv TPDAYEAGTWGPESSLEMLRRTGREWRRP----
Mb1482c|M.bovis_AF2122/97 TPDAYEAGTWGPESSLEMLRRTGREWRRP----
MAV_3329|M.avium_104 RPEPYEAGTWGPDSAFEMLHRTGREWRGHDTQR
MMAR_2252|M.marinum_M KPDPYEAGTWGPESAFEMLRRTGREWRRP----
MUL_1842|M.ulcerans_Agy99 KPDPYEAGTWGPESAFEMLRRTGREWRRP----
Mflv_3694|M.gilvum_PYR-GCK PLDPYVSGTWGPPSANDMVRRLDREWRRP----
Mvan_2718|M.vanbaalenii_PYR-1 RPEPYESGTWGPPSAYDMVHLLDREWRRP----
TH_0337|M.thermoresistible__bu KPDPYEAGTWGPESAFEMLRRTGREWRRP----
MSMEG_3101|M.smegmatis_MC2_155 KPEPYESGTWGPPSADAMLRRTGREWRRP----
MAB_2761|M.abscessus_ATCC_1997 RPDTYESGTWGPQSAVEMLARSGREWRRP----
:.* :***** *: *: .****