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VGYAEPVLIERQSVVAAPAEQVWQRVVTPEGINDELRPWMTMSVPRGAKGMTVDTVPIGAPIGRAWLRLF GVLPFDYDRLSIAELEPGRRFREDSTMLSMRQWQHERTVTPEGDTKTIVRDRITFQTRAGLRFAAPLIAA GLRALFGHRHRRLQRHFAQG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1443c | - | - | 100% (161) | hypothetical protein Rv1443c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1478c | - | 1e-91 | 100.00% (161) | hypothetical protein Mb1478c |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1687 | - | 9e-34 | 44.87% (156) | hypothetical protein MAB_1687 |
| M. marinum M | MMAR_0169 | - | 8e-32 | 43.87% (155) | hypothetical protein MMAR_0169 |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_3083 | - | 4e-05 | 25.00% (144) | nucleoside-diphosphate sugar epimerase |
| M. thermoresistible (build 8) | TH_2675 | - | 4e-05 | 26.90% (145) | PUTATIVE domain of unknown function DUF1731 |
| M. ulcerans Agy99 | MUL_4927 | - | 1e-32 | 43.87% (155) | hypothetical protein MUL_4927 |
| M. vanbaalenii PYR-1 | Mvan_3512 | - | 8e-08 | 29.41% (153) | hypothetical protein Mvan_3512 |
CLUSTAL 2.0.9 multiple sequence alignment
TH_2675|M.thermoresistible__bu ------MGIE--YESVVPHPIADVFAWYGRPGALTRLIPPWQPMTAVAEA
Mvan_3512|M.vanbaalenii_PYR-1 ------MGIE--YESVVEHPRDDVWQWHARPGAMRRLVPPWQPMSVVSEA
MSMEG_3083|M.smegmatis_MC2_155 -----MMCSERVFSTVVDAPRDEVFAWHARPGAIHRLFPPWQPLRIEAEA
Rv1443c|M.tuberculosis_H37Rv MVG-YAEPVLIERQSVVAAPAEQVWQRVVTPEGINDELRPWMTMSVPRGA
Mb1478c|M.bovis_AF2122/97 MVG-YAEPVLIERQSVVAAPAEQVWQRVVTPEGINDELRPWMTMSVPRGA
MMAR_0169|M.marinum_M MRSIHTDEHVFRKVSEIDCPVERVWQTVTTQEGINHEMGPYMKMTMPKQF
MUL_4927|M.ulcerans_Agy99 MRSIHTDEHVFRKVSEIDCPVERVWQTVTTQEGINHEMGPYMKMTMPKQF
MAB_1687|M.abscessus_ATCC_1997 MRSIHTEEHVFRKVSEIDCPVDKVWERVTTQEGINDEMGPYMKMTMPKQF
: : * *: .: . *: :
TH_2675|M.thermoresistible__bu ASLADGRAVLALPGGLRWVAQHDPAGYVPPRRFVDTLASGGPRSWPTRLI
Mvan_3512|M.vanbaalenii_PYR-1 ESLADGVAVLGLPGGLRWVARHDPAEYVAGRRFVDELSSDGPASWPPRVI
MSMEG_3083|M.smegmatis_MC2_155 ASLADGTARLALPGGLTWVARHVAESYDPPRCFVDTIATDGVTSLPARAV
Rv1443c|M.tuberculosis_H37Rv KGMTVDTVPIGAPIGRAWLRLFGVLPFDYDRLSIAELEPGRRFREDSTML
Mb1478c|M.bovis_AF2122/97 KGMTVDTVPIGAPIGRAWLRLFGVLPFDYDRLSIAELEPGRRFREDSTML
MMAR_0169|M.marinum_M IGRSIADVEPGTRIGKSFLLLFGFLPFGFDDITITRIEPGRMFREESTMT
MUL_4927|M.ulcerans_Agy99 IGRSIADVEPGTRIGKSFLLLFGFLPFGFDDITITRIEPGRMFREESTMT
MAB_1687|M.abscessus_ATCC_1997 RGKSIADVTPGTRIGKSFLLLFGVLPFGFDDITVARLEPGRMFREESLMT
. : . . * :: . : : : .. .
TH_2675|M.thermoresistible__bu GH--WQHIHEFDPVDDGHTRVRDRVRAPVPRALLEPMLRYRHRQLADDLA
Mvan_3512|M.vanbaalenii_PYR-1 GG--WRHTHTFADADGG-TRVHDQVDTAVPAAALRSTFVYRHRQLADDLA
MSMEG_3083|M.smegmatis_MC2_155 VR--WRHIHEFDDTGDGRTRMTDRVQTYVPERALRPMFAYRHRQLADDLA
Rv1443c|M.tuberculosis_H37Rv SMRQWQHERTVTPEGDTKTIVRDRIT-FQTRAGLR---------------
Mb1478c|M.bovis_AF2122/97 SMRQWQHERTVTPEGDTKTIVRDRIT-FQTRAGLR---------------
MMAR_0169|M.marinum_M GMRVWVHHRTLEPKGD-KTVVSDEIT-LAPQAPMG---------------
MUL_4927|M.ulcerans_Agy99 GMRVWVHHRTLEPKGD-KTVVSDEIT-LAPQAPMG---------------
MAB_1687|M.abscessus_ATCC_1997 GMRIWVHHRTLEPLGD-KTIVTDEVT-LAPQAPMG---------------
* * : . .. * : *.: . :
TH_2675|M.thermoresistible__bu AHREAAAARAGPWTLAVTGASGLVGSALTALLSTGGHRVIRLVRRPARGP
Mvan_3512|M.vanbaalenii_PYR-1 AHRRAAEAGAAPMVVAITGASGLVGSALSAFLSTGGHRVIRLVRGPARGA
MSMEG_3083|M.smegmatis_MC2_155 AHRQARAHGLKPMTIAVTGSSGLVGTALSALLSTGGHRVIRLVRRAPAGP
Rv1443c|M.tuberculosis_H37Rv ---------------FAA---PLIAAGLRALFG---HRHRRLQRHFAQG-
Mb1478c|M.bovis_AF2122/97 ---------------FAA---PLIAAGLRALFG---HRHRRLQRHFAQG-
MMAR_0169|M.marinum_M ---------------LIPGWGKLMSKILSAFFT---HRHRRLCKSLAKTG
MUL_4927|M.ulcerans_Agy99 ---------------LIPGWGKLMSKILSAFFA---HRHRRLRKSLAKTG
MAB_1687|M.abscessus_ATCC_1997 ---------------LIPGWGRLLSKILAAFFT---HRHRRLSRTLSATG
. *:. * *:: ** ** : .
TH_2675|M.thermoresistible__bu GERRWEPEYPAPDLLDGVDTVIHLAGASIAGRFTAQHRAAIRDSRIGPTR
Mvan_3512|M.vanbaalenii_PYR-1 HERQWDPRDPAPDLLTGVDAVVHLAGASIAGRFTEAHRAAIRDSRIEPTR
MSMEG_3083|M.smegmatis_MC2_155 GERRWNPDDPHPELLTGVDAVIHLAGASIAGRFTDEHRRAIRDSRVGPTR
Rv1443c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1478c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0169|M.marinum_M VAQ-----------------------------------------------
MUL_4927|M.ulcerans_Agy99 VAQ-----------------------------------------------
MAB_1687|M.abscessus_ATCC_1997 VPR-----------------------------------------------
TH_2675|M.thermoresistible__bu RLAELAGRAA-GVRTFVSASAIGYYGPDRGDDLLTEADARGDGFLADVVA
Mvan_3512|M.vanbaalenii_PYR-1 LLASAAASAPDGPRTFVSASAIGFYGFDRGDTQLTEDSTRGDGFLADVVA
MSMEG_3083|M.smegmatis_MC2_155 RLAELA--AATGLETFVSASAIGFYGACPGG-PVTEESGRGDGFLADVVA
Rv1443c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1478c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0169|M.marinum_M --------------------------------------------------
MUL_4927|M.ulcerans_Agy99 --------------------------------------------------
MAB_1687|M.abscessus_ATCC_1997 --------------------------------------------------
TH_2675|M.thermoresistible__bu DWEAATEPALAAGVRVVCVRTGIVQAARGGTLRVLRPLFSAGLGGPIGGG
Mvan_3512|M.vanbaalenii_PYR-1 DWEAATTPAADAGLRVVKVRTGIVQAAAGGTLHLLRPLFAAGLGGRLGSG
MSMEG_3083|M.smegmatis_MC2_155 QWEDAAAAAEQAGVRVVRVRTGVVQSPRGGILRVLAPLFRLGLGGRVGDG
Rv1443c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1478c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0169|M.marinum_M --------------------------------------------------
MUL_4927|M.ulcerans_Agy99 --------------------------------------------------
MAB_1687|M.abscessus_ATCC_1997 --------------------------------------------------
TH_2675|M.thermoresistible__bu TQWLSWIGLDDLLDVYHRAAYDIRLTGPVNAVAPHPVRNSDYTAALAGVL
Mvan_3512|M.vanbaalenii_PYR-1 RQWLSWIGLDDLVEVYHRALYDDGLSGPVNAVGPDPVRNSDYTRELARVL
MSMEG_3083|M.smegmatis_MC2_155 AQWLSWIGIDDLVDIYLRALWDTDLTGPVNAVAPEPVRNSQYTRTLARVL
Rv1443c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1478c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0169|M.marinum_M --------------------------------------------------
MUL_4927|M.ulcerans_Agy99 --------------------------------------------------
MAB_1687|M.abscessus_ATCC_1997 --------------------------------------------------
TH_2675|M.thermoresistible__bu RRPARIPVPPAVPRLLLGAQGATELALADQRVVPAELQRLGHRFRHRTIT
Mvan_3512|M.vanbaalenii_PYR-1 HRPALLPVPALGPRILLGEQGARELAMASQRVVPSKLLAAGQPFRHPDLR
MSMEG_3083|M.smegmatis_MC2_155 HRPAVLPVPAAGPRLLLGEQGAREVALASQHVTSAELRRAGHRFRHPDLE
Rv1443c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1478c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0169|M.marinum_M --------------------------------------------------
MUL_4927|M.ulcerans_Agy99 --------------------------------------------------
MAB_1687|M.abscessus_ATCC_1997 --------------------------------------------------
TH_2675|M.thermoresistible__bu EALAHQLGRG
Mvan_3512|M.vanbaalenii_PYR-1 GALAHQLGRE
MSMEG_3083|M.smegmatis_MC2_155 SALRHVLG--
Rv1443c|M.tuberculosis_H37Rv ----------
Mb1478c|M.bovis_AF2122/97 ----------
MMAR_0169|M.marinum_M ----------
MUL_4927|M.ulcerans_Agy99 ----------
MAB_1687|M.abscessus_ATCC_1997 ----------