For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. tuberculosis H37Rv Rv1416 (ribH)

annotation: riboflavin synthase subunit beta
coordinates: 1591689 - 1592153
length: 154

VPDLPSLDASGVRLAIVASSWHGKICDALLDGARKVAAGCGLDDPTVVRVLGAIEIPVVAQELARNHDAV
VALGVVIRGQTPHFDYVCDAVTQGLTRVSLDSSTPIANGVLTTNTEEQALDRAGLPTSAEDKGAQATVAA
LATALTLRELRAHS
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv1416ribH-100% (154)riboflavin synthase subunit beta

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1451ribH2e-83100.00% (154) 6,7-dimethyl-8-ribityllumazine synthase
M. gilvum PYR-GCKMflv_3718ribH3e-6680.52% (154) riboflavin synthase subunit beta
M. leprae Br4923MLBr_00560ribH6e-6778.95% (152) 6,7-dimethyl-8-ribityllumazine synthase
M. abscessus ATCC 19977MAB_2795c-6e-6176.16% (151) 6,7-dimethyl-8-ribityllumazine synthase
M. marinum MMMAR_2223ribH3e-7084.42% (154) riboflavin synthase beta chain RibH
M. avium 104MAV_3364ribH2e-6983.12% (154) riboflavin synthase subunit beta
M. smegmatis MC2 155MSMEG_3073ribH5e-6681.46% (151) riboflavin synthase subunit beta
M. thermoresistible (build 8)TH_1012ribH5e-7084.87% (152) PROBABLE RIBOFLAVIN SYNTHASE BETA CHAIN RIBH
M. ulcerans Agy99MUL_1810ribH4e-7185.06% (154) 6,7-dimethyl-8-ribityllumazine synthase
M. vanbaalenii PYR-1Mvan_2695ribH9e-7085.33% (150) riboflavin synthase subunit beta

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3718|M.gilvum_PYR-GCK          MS-GAGVPDMPALHAEDVTLAIVASTWHETICDALLDGARKVAEQAGVTD
Mvan_2695|M.vanbaalenii_PYR-1       MSPAAGVPELPALDGKGLRLAIVASTWHETICDALLDGARKVAVGAGIDD
Rv1416|M.tuberculosis_H37Rv         ------MPDLPSLDASGVRLAIVASSWHGKICDALLDGARKVAAGCGLDD
Mb1451|M.bovis_AF2122/97            ------MPDLPSLDASGVRLAIVASSWHGKICDALLDGARKVAAGCGLDD
MMAR_2223|M.marinum_M               MSGGAGIPDVPAFDASDVRLAIVASTWHTKICDALLAGARNTAADSGIDN
MUL_1810|M.ulcerans_Agy99           MSGGAGIPDVPAFDASGVRLAIVASTWHTKICDALLAGARNTAADSGIDN
MLBr_00560|M.leprae_Br4923          MSGGAGIPEVPGIDASGLRLGIVASTWHSRICDALLAGARKVAADSGIDG
MAV_3364|M.avium_104                MSPAAGVPEMPALDASGVRLGIVASTWHSRICDALLAGARKVAADSGVEN
TH_1012|M.thermoresistible__bu      -VSKAGVPDLPQLDASGLKLAIVASTWHQKICDALLDGARKVAADAGITD
MAB_2795c|M.abscessus_ATCC_199      -MSGDGIPSLSVGDASGISLAIVASTWHDQICTALLEGAQRVATEAGIDR
MSMEG_3073|M.smegmatis_MC2_155      -MSGVGVPDLPEIDASSLTLAIVASTWHTEICDALLEGARKVAADAGIPD
                                          :*.:.  ....: *.****:**  ** *** **:..*  .*:  

Mflv_3718|M.gilvum_PYR-GCK          PTVVRVLGAIEIPVVAQALARTHDAVIALGVVIRGETPHFDYVCDAVTQG
Mvan_2695|M.vanbaalenii_PYR-1       PTVVRVLGAIEIPVVAQALARTHDAVVALGVVIRGETPHFDYVCDAVTQG
Rv1416|M.tuberculosis_H37Rv         PTVVRVLGAIEIPVVAQELARNHDAVVALGVVIRGQTPHFDYVCDAVTQG
Mb1451|M.bovis_AF2122/97            PTVVRVLGAIEIPVVAQELARNHDAVVALGVVIRGQTPHFDYVCDAVTQG
MMAR_2223|M.marinum_M               PTVVRVLGAIEIPVVAQELTRNHDAVVALGVVIRGETPHFDYVCDAVTQG
MUL_1810|M.ulcerans_Agy99           PTVVRVLGAIEIPVVAQELTRNHDAVVALGVVIRGETPHFDYVCDVVTQG
MLBr_00560|M.leprae_Br4923          PTVVRVLGAIEIPVVVQELARHHDAVVALGVVIRGDTPHFDYVCNSVTQG
MAV_3364|M.avium_104                PTVVRVLGAIEIPVVAQELARNHDAVVALGVVIRGQTPHFEYVCDAVTQG
TH_1012|M.thermoresistible__bu      PTVVRVLGAIEIPVVAQALAANHDAVIALGVVIRGETPHFDYVCDAVTQG
MAB_2795c|M.abscessus_ATCC_199      PTVVRVLGAIEIPVVAQALARTHDAVVALGVVIQGETPHFGYVCDAVTTG
MSMEG_3073|M.smegmatis_MC2_155      PTVVRVLGAIEIPVVAQALARTHDAVVALGVVIQGETPHFDYVCDAVTQG
                                    ***************.* *:  ****:******:*:**** ***: ** *

Mflv_3718|M.gilvum_PYR-GCK          LTRVSLDASTPVANGVLTVNTENQALDRAGLPNSAEDKGAQAAAAALSTA
Mvan_2695|M.vanbaalenii_PYR-1       LTRVSLDASTPVANGVLTTNTEHQALDRAGLPDSAEDKGAQAAAAALSTA
Rv1416|M.tuberculosis_H37Rv         LTRVSLDSSTPIANGVLTTNTEEQALDRAGLPTSAEDKGAQATVAALATA
Mb1451|M.bovis_AF2122/97            LTRVSLDSSTPIANGVLTTNTEEQALDRAGLPTSAEDKGAQATVAALATA
MMAR_2223|M.marinum_M               LTRVSLDSSTPVANGVLTTNSEEQALNRAGLPTSDEDKGAQATAAALTTA
MUL_1810|M.ulcerans_Agy99           LTRVSLDSSTPVANGVLTTNSEEQALNRAGLPTSDEDKGAQATAAALTTA
MLBr_00560|M.leprae_Br4923          LTRIALDTSTPVGNGVLTTNTEKQALDRAGLPTSAEDKGAQAAAAALTTA
MAV_3364|M.avium_104                ITRVSLDASTPVANGVLTTDNEQQALDRAGLPDSAEDKGAQAAGAALSAA
TH_1012|M.thermoresistible__bu      LTRVSLDASTPVANGVLTTDTEAQALDRAGLPGSAEDKGGQAAAAALSTA
MAB_2795c|M.abscessus_ATCC_199      LTRVSLDTSTPVANGVLTVNNEQQAIDRAGLPGSAEDKGAQAAAAALDTA
MSMEG_3073|M.smegmatis_MC2_155      LTRVSLDEATPVANGVLTTNTEEQARARAGLPGSTEDKGAQAAAAALSTA
                                    :**::** :**:.*****.:.* **  ***** * ****.**: *** :*

Mflv_3718|M.gilvum_PYR-GCK          LTLRQLASPS-
Mvan_2695|M.vanbaalenii_PYR-1       LTLRQLS----
Rv1416|M.tuberculosis_H37Rv         LTLRELRAHS-
Mb1451|M.bovis_AF2122/97            LTLRELRAHS-
MMAR_2223|M.marinum_M               LTLRELRAEA-
MUL_1810|M.ulcerans_Agy99           LTLRELRAES-
MLBr_00560|M.leprae_Br4923          LTLLNLRSRI-
MAV_3364|M.avium_104                LTLRELRARS-
TH_1012|M.thermoresistible__bu      LTLRELRSQI-
MAB_2795c|M.abscessus_ATCC_199      LTLRRLRQPWA
MSMEG_3073|M.smegmatis_MC2_155      VTLRELRRA--
                                    :** .*