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M. leprae Br4923 MLBr_00560 (ribH)

annotation: 6,7-dimethyl-8-ribityllumazine synthase
coordinates: 677615 - 678097
length: 160

MSGGAGIPEVPGIDASGLRLGIVASTWHSRICDALLAGARKVAADSGIDGPTVVRVLGAIEIPVVVQELA
RHHDAVVALGVVIRGDTPHFDYVCNSVTQGLTRIALDTSTPVGNGVLTTNTEKQALDRAGLPTSAEDKGA
QAAAAALTTALTLLNLRSRI
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. leprae Br4923MLBr_00560ribH-100% (160)6,7-dimethyl-8-ribityllumazine synthase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1451ribH2e-6678.95% (152) 6,7-dimethyl-8-ribityllumazine synthase
M. gilvum PYR-GCKMflv_3718ribH3e-6375.48% (155) riboflavin synthase subunit beta
M. tuberculosis H37RvRv1416ribH2e-6678.95% (152) 6,7-dimethyl-8-ribityllumazine synthase
M. abscessus ATCC 19977MAB_2795c-2e-6074.68% (154) 6,7-dimethyl-8-ribityllumazine synthase
M. marinum MMMAR_2223ribH4e-7081.01% (158) riboflavin synthase beta chain RibH
M. avium 104MAV_3364ribH1e-7080.50% (159) riboflavin synthase subunit beta
M. smegmatis MC2 155MSMEG_3073ribH1e-6377.27% (154) riboflavin synthase subunit beta
M. thermoresistible (build 8)TH_1012ribH5e-6778.85% (156) PROBABLE RIBOFLAVIN SYNTHASE BETA CHAIN RIBH
M. ulcerans Agy99MUL_1810ribH1e-7081.65% (158) 6,7-dimethyl-8-ribityllumazine synthase
M. vanbaalenii PYR-1Mvan_2695ribH8e-6780.13% (156) riboflavin synthase subunit beta

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3718|M.gilvum_PYR-GCK          MS-GAGVPDMPALHAEDVTLAIVASTWHETICDALLDGARKVAEQAGVTD
Mvan_2695|M.vanbaalenii_PYR-1       MSPAAGVPELPALDGKGLRLAIVASTWHETICDALLDGARKVAVGAGIDD
MMAR_2223|M.marinum_M               MSGGAGIPDVPAFDASDVRLAIVASTWHTKICDALLAGARNTAADSGIDN
MUL_1810|M.ulcerans_Agy99           MSGGAGIPDVPAFDASGVRLAIVASTWHTKICDALLAGARNTAADSGIDN
MLBr_00560|M.leprae_Br4923          MSGGAGIPEVPGIDASGLRLGIVASTWHSRICDALLAGARKVAADSGIDG
MAV_3364|M.avium_104                MSPAAGVPEMPALDASGVRLGIVASTWHSRICDALLAGARKVAADSGVEN
Mb1451|M.bovis_AF2122/97            ------MPDLPSLDASGVRLAIVASSWHGKICDALLDGARKVAAGCGLDD
Rv1416|M.tuberculosis_H37Rv         ------MPDLPSLDASGVRLAIVASSWHGKICDALLDGARKVAAGCGLDD
TH_1012|M.thermoresistible__bu      -VSKAGVPDLPQLDASGLKLAIVASTWHQKICDALLDGARKVAADAGITD
MAB_2795c|M.abscessus_ATCC_199      -MSGDGIPSLSVGDASGISLAIVASTWHDQICTALLEGAQRVATEAGIDR
MSMEG_3073|M.smegmatis_MC2_155      -MSGVGVPDLPEIDASSLTLAIVASTWHTEICDALLEGARKVAADAGIPD
                                          :*.:.  ....: *.****:**  ** *** **:..*  .*:  

Mflv_3718|M.gilvum_PYR-GCK          PTVVRVLGAIEIPVVAQALARTHDAVIALGVVIRGETPHFDYVCDAVTQG
Mvan_2695|M.vanbaalenii_PYR-1       PTVVRVLGAIEIPVVAQALARTHDAVVALGVVIRGETPHFDYVCDAVTQG
MMAR_2223|M.marinum_M               PTVVRVLGAIEIPVVAQELTRNHDAVVALGVVIRGETPHFDYVCDAVTQG
MUL_1810|M.ulcerans_Agy99           PTVVRVLGAIEIPVVAQELTRNHDAVVALGVVIRGETPHFDYVCDVVTQG
MLBr_00560|M.leprae_Br4923          PTVVRVLGAIEIPVVVQELARHHDAVVALGVVIRGDTPHFDYVCNSVTQG
MAV_3364|M.avium_104                PTVVRVLGAIEIPVVAQELARNHDAVVALGVVIRGQTPHFEYVCDAVTQG
Mb1451|M.bovis_AF2122/97            PTVVRVLGAIEIPVVAQELARNHDAVVALGVVIRGQTPHFDYVCDAVTQG
Rv1416|M.tuberculosis_H37Rv         PTVVRVLGAIEIPVVAQELARNHDAVVALGVVIRGQTPHFDYVCDAVTQG
TH_1012|M.thermoresistible__bu      PTVVRVLGAIEIPVVAQALAANHDAVIALGVVIRGETPHFDYVCDAVTQG
MAB_2795c|M.abscessus_ATCC_199      PTVVRVLGAIEIPVVAQALARTHDAVVALGVVIQGETPHFGYVCDAVTTG
MSMEG_3073|M.smegmatis_MC2_155      PTVVRVLGAIEIPVVAQALARTHDAVVALGVVIQGETPHFDYVCDAVTQG
                                    ***************.* *:  ****:******:*:**** ***: ** *

Mflv_3718|M.gilvum_PYR-GCK          LTRVSLDASTPVANGVLTVNTENQALDRAGLPNSAEDKGAQAAAAALSTA
Mvan_2695|M.vanbaalenii_PYR-1       LTRVSLDASTPVANGVLTTNTEHQALDRAGLPDSAEDKGAQAAAAALSTA
MMAR_2223|M.marinum_M               LTRVSLDSSTPVANGVLTTNSEEQALNRAGLPTSDEDKGAQATAAALTTA
MUL_1810|M.ulcerans_Agy99           LTRVSLDSSTPVANGVLTTNSEEQALNRAGLPTSDEDKGAQATAAALTTA
MLBr_00560|M.leprae_Br4923          LTRIALDTSTPVGNGVLTTNTEKQALDRAGLPTSAEDKGAQAAAAALTTA
MAV_3364|M.avium_104                ITRVSLDASTPVANGVLTTDNEQQALDRAGLPDSAEDKGAQAAGAALSAA
Mb1451|M.bovis_AF2122/97            LTRVSLDSSTPIANGVLTTNTEEQALDRAGLPTSAEDKGAQATVAALATA
Rv1416|M.tuberculosis_H37Rv         LTRVSLDSSTPIANGVLTTNTEEQALDRAGLPTSAEDKGAQATVAALATA
TH_1012|M.thermoresistible__bu      LTRVSLDASTPVANGVLTTDTEAQALDRAGLPGSAEDKGGQAAAAALSTA
MAB_2795c|M.abscessus_ATCC_199      LTRVSLDTSTPVANGVLTVNNEQQAIDRAGLPGSAEDKGAQAAAAALDTA
MSMEG_3073|M.smegmatis_MC2_155      LTRVSLDEATPVANGVLTTNTEEQARARAGLPGSTEDKGAQAAAAALSTA
                                    :**::** :**:.*****.:.* **  ***** * ****.**: *** :*

Mflv_3718|M.gilvum_PYR-GCK          LTLRQLASPS-
Mvan_2695|M.vanbaalenii_PYR-1       LTLRQLS----
MMAR_2223|M.marinum_M               LTLRELRAEA-
MUL_1810|M.ulcerans_Agy99           LTLRELRAES-
MLBr_00560|M.leprae_Br4923          LTLLNLRSRI-
MAV_3364|M.avium_104                LTLRELRARS-
Mb1451|M.bovis_AF2122/97            LTLRELRAHS-
Rv1416|M.tuberculosis_H37Rv         LTLRELRAHS-
TH_1012|M.thermoresistible__bu      LTLRELRSQI-
MAB_2795c|M.abscessus_ATCC_199      LTLRRLRQPWA
MSMEG_3073|M.smegmatis_MC2_155      VTLRELRRA--
                                    :** .*