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MNGLISQACGSHRPRRPSSLGAVAILIAATLFATVVAGCGKKPTTASSPSPGSPSPEAQQILQDSSKATK GLHSVHVVVTVNNLSTLPFESVDADVTNQPQGNGQAVGNAKVRMKPNTPVVATEFLVTNKTMYTKRGGDY VSVGPAEKIYDPGIILDKDRGLGAVVGQVQNPTIQGRDAIDGLATVKVSGTIDAAVIDPIVPQLGKGGGR LPITLWIVDTNASTPAPAANLVRMVIDKDQGNVDITLSNWGAPVTIPNPAG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1368 | lprF | - | 100% (261) | PROBABLE CONSERVED LIPOPROTEIN LPRF |
| M. tuberculosis H37Rv | Rv1411c | lprG | 3e-29 | 32.50% (240) | lipoprotein LprG |
| M. tuberculosis H37Rv | Rv2945c | lppX | 8e-17 | 30.29% (241) | lipoprotein LppX |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1403 | lprF | 1e-149 | 100.00% (261) | putative lipoprotein lprF |
| M. gilvum PYR-GCK | Mflv_3724 | - | 6e-27 | 30.99% (242) | hypothetical protein Mflv_3724 |
| M. leprae Br4923 | MLBr_00557 | lprG | 4e-23 | 31.67% (240) | putative lipoprotein |
| M. abscessus ATCC 19977 | MAB_2806 | - | 5e-21 | 30.17% (242) | lipoprotein LprG precursor (27 kDa lipoprotein) |
| M. marinum M | MMAR_2188 | lprF | 1e-107 | 68.84% (292) | lipoprotein LprF |
| M. avium 104 | MAV_3367 | - | 2e-28 | 30.54% (239) | LprG protein |
| M. smegmatis MC2 155 | MSMEG_3070 | - | 1e-24 | 31.12% (241) | LprG protein |
| M. thermoresistible (build 8) | TH_1009 | lprG | 6e-25 | 31.09% (238) | PROBABLE CONSERVED LIPOPROTEIN LPRG |
| M. ulcerans Agy99 | MUL_1773 | lprF | 1e-106 | 68.49% (292) | lipoprotein LprF |
| M. vanbaalenii PYR-1 | Mvan_2692 | - | 2e-27 | 33.88% (242) | hypothetical protein Mvan_2692 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3724|M.gilvum_PYR-GCK ------------------------------------------MPPGRPAA
Mvan_2692|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_3070|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_00557|M.leprae_Br4923 --------------------------------------------------
MAV_3367|M.avium_104 --------------------------------------------------
TH_1009|M.thermoresistible__bu --------------------------------------------------
MAB_2806|M.abscessus_ATCC_1997 --------------------------------------------------
Rv1368|M.tuberculosis_H37Rv --------------------------------------------------
Mb1403|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2188|M.marinum_M --------------------------------------------------
MUL_1773|M.ulcerans_Agy99 MTAVLLLVNQGAGCSHQDPPPWTGPNWLALSMCYDEGSDPLLITTGRITQ
Mflv_3724|M.gilvum_PYR-GCK RSTRPDTRTLYDAGMQTR------------LLAIFAALFAAVALLAGCSS
Mvan_2692|M.vanbaalenii_PYR-1 --------------MQTR------------LLAIFAALFAVVALVAGCSG
MSMEG_3070|M.smegmatis_MC2_155 --------------MQTRP--------RFAVQSLFAILATAAALVAGCS-
MLBr_00557|M.leprae_Br4923 --------------MQAPK-------HHRRLFAVLATLNTATAVIAGCS-
MAV_3367|M.avium_104 --------------MQT----------RRRLSAVFASLTLATALIAGCS-
TH_1009|M.thermoresistible__bu --------------MQTRFRHAGRTVPVRNLFALFALVALIVG-VAGCSS
MAB_2806|M.abscessus_ATCC_1997 --------------MRNR------------IRLALIPVAVAAIALAGCS-
Rv1368|M.tuberculosis_H37Rv ----MNGLISQACGSHRP-----RRPSSLGAVAILIAATLFATVVAGCGK
Mb1403|M.bovis_AF2122/97 ----MNGLISQACGSHRP-----RRPSSLGAVAILIAATLFATVVAGCGK
MMAR_2188|M.marinum_M ----MNGLISQAHTSHRLLSRPCRRFSTPTSVAILFATALVATVMTGCGH
MUL_1773|M.ulcerans_Agy99 QRLAMNGLISQAHTSHRLLSRPCRRFSTPTSVAILFATALVATVMTGCGH
: : . ::**.
Mflv_3724|M.gilvum_PYR-GCK --SSTEDSGK-----------------DLPDPTTLLSESSETTRNQTSAH
Mvan_2692|M.vanbaalenii_PYR-1 --SSSKDSGK-----------------ELPDAATLLQRSSETTKAQTSAH
MSMEG_3070|M.smegmatis_MC2_155 --SSSETSDA-----------------PLPDGAALLQESASKTKTQQSVH
MLBr_00557|M.leprae_Br4923 --SGSNLSSG-----------------PLPDATTWVKQATDITKNVTSAH
MAV_3367|M.avium_104 --SGSKQSGA-----------------PLPDPTSLVKQSADATKNVKSVH
TH_1009|M.thermoresistible__bu GEDQADQSEQ-----------------PTPDAATLLEEAAQTTRDLQSVR
MAB_2806|M.abscessus_ATCC_1997 ---KTDKADP-----------------NLPEAATLLSESAATTKTQTSTH
Rv1368|M.tuberculosis_H37Rv KPTTASSPSP---------------GSPSPEAQQILQDSSKATKGLHSVH
Mb1403|M.bovis_AF2122/97 KPTTASSPSP---------------GSPSPEAQQILQDSSKATKGLHSVH
MMAR_2188|M.marinum_M KSTTATSQTPGASGTSATTATSGATGAPSPQAQQILQDSSKATKGLHSVH
MUL_1773|M.ulcerans_Agy99 KSTTATSQTPGASGTSATTATSGATGAPSPQAQQILQDSSKATKGLHSVH
: *: :. :: *: *.:
Mflv_3724|M.gilvum_PYR-GCK LTLSVQGQIAELPVEQLEGDLTQTP---AVAAKGTANIIFLGQRLNDVEF
Mvan_2692|M.vanbaalenii_PYR-1 LNLSVQGQIPDLPVESLEGDLTQSP---AVAAKGTANIIFLGQRLNDVAF
MSMEG_3070|M.smegmatis_MC2_155 LLLTVQGKVDGLPVEKLDGDLTNAP---AVAAEGTADLIAFGQKIADAKF
MLBr_00557|M.leprae_Br4923 LVLSVNGKITGLPVKTLTGDLTTHP---NTVASGNATITLDGADLN-ANF
MAV_3367|M.avium_104 LVLSIQGKISGLPIKTLTGDLTTTP---ATAAKGNATITLGGSDID-ANF
TH_1009|M.thermoresistible__bu LDLTVQGEIPELPIETLQGDLTNVP---EVGATGTADIIMMGQRFEDVDF
MAB_2806|M.abscessus_ATCC_1997 IVLKVTGDKPTLKLSDLTGDLTTKP---AVAAKGTAKT--GGLELP---F
Rv1368|M.tuberculosis_H37Rv VVVTVN-NLSTLPFESVDADVTNQPQGNGQAVGNAKVRMKPNTPVVATEF
Mb1403|M.bovis_AF2122/97 VVVTVN-NLSTLPFESVDADVTNQPQGNGQAVGNAKVRMKPNTPVVATEF
MMAR_2188|M.marinum_M VAVNVT-DLPKLPFESVNADVTNQPQGNGQAVGNAKVRMQPDAPAVATDF
MUL_1773|M.ulcerans_Agy99 VAVNVT-DLPKLPFESVNADVTNQPQGNGQAVGNAKVRMQPDAPAVATDF
: :.: . * .. : .*:* * . . . *
Mflv_3724|M.gilvum_PYR-GCK VVSDGDLWATITAGGSLSNFGPAADVYDVAAILDPNVGLANVLANFSN-P
Mvan_2692|M.vanbaalenii_PYR-1 VVSDGDLYAAITAGGALSNFGPASDVYDVAAILNPDVGLANVLANFSN-P
MSMEG_3070|M.smegmatis_MC2_155 VIADGNLYAALTPGDPLSNYGAAANIYDVSAILNPDTGLANVLANFSD-A
MLBr_00557|M.leprae_Br4923 VVVDGELYATLTPS-KWSDFGKASDIYDVASILNPDAGLANVLANFTG-A
MAV_3367|M.avium_104 VVVDGTLYATLTPN-KWSDFGKASDIYDVSVLLNPDNGLGNALANFSN-A
TH_1009|M.thermoresistible__bu VVAEGNLFAALAAG-DYIDFGPAADIYDVSAILNPDTGLANLLANFSDDA
MAB_2806|M.abscessus_ATCC_1997 VVVDGELFAQLGSA--YSSMGPVKDVYDVGLILDPNKGLANLLANITG-A
Rv1368|M.tuberculosis_H37Rv LVTNKTMYTKRGGD--YVSVGPAEKIYDPGIILDKDRGLGAVVGQVQN-P
Mb1403|M.bovis_AF2122/97 LVTNKTMYTKRGGD--YVSVGPAEKIYDPGIILDKDRGLGAVVGQVQN-P
MMAR_2188|M.marinum_M LVTNKTMYTKNGET--YTSVGPAQRIYDPGIILDKDRGLGAVIAQVQN-P
MUL_1773|M.ulcerans_Agy99 LVTNKTMYTKNGET--YTSVGPAQRIYDPGIILDKDRGLGAVIAQVQN-P
:: : ::: . * . :** . :*: : **. :.:. . .
Mflv_3724|M.gilvum_PYR-GCK SADGRETVEGTQTVRVTGEVSADAVNKIAPQIGATGP-VPGTAWVAEEGD
Mvan_2692|M.vanbaalenii_PYR-1 TADGREEVKGAQTVRVTGEVSADAVNKIAPQIAATGP-VPGTAWITEDGD
MSMEG_3070|M.smegmatis_MC2_155 TADGRESINGTEAVRVKGNVSADAVNKIAPALKADGP-VPGTAWITED-D
MLBr_00557|M.leprae_Br4923 KTEGRDSINGQSAVRISGNVSADAVNKIAPPFNATQP-MPATVWIQETGD
MAV_3367|M.avium_104 KAEGRETINGQSTIRISGNVSADAVNKIMPQFNATQP-VPSTVWVQETGD
TH_1009|M.thermoresistible__bu TVEGRETINGVRTLHVTGTVTPEAVNAIAPQIGAEAP-VPAGAWIRADGA
MAB_2806|M.abscessus_ATCC_1997 KSEKTETIDGVDSVLVTGTMSKDALNTFTGGTTLTAD-IPAKAWIQKDGN
Rv1368|M.tuberculosis_H37Rv TIQGRDAIDGLATVKVSGTIDAAVIDPIVPQLGKGGGRLPITLWIVDTNA
Mb1403|M.bovis_AF2122/97 TIQGRDAIDGLATVKVSGTIDAAVIDPIVPQLGKGGGRLPITLWIVDTNA
MMAR_2188|M.marinum_M KIEGNETVDGMATVKVSGTIDGAVIDPIVPQLGKDGGTMPITLWIVDTSA
MUL_1773|M.ulcerans_Agy99 KIEGNETVDGMATVKVSGTIDGAVIDSIVPQLGKDGGTMPITLWIVDTSA
. : : :.* :: :.* : .:: : :* *:
Mflv_3724|M.gilvum_PYR-GCK HKLMQ---------------VRLE-PSPGNSVTMTLSKWGEPVTVDKPAV
Mvan_2692|M.vanbaalenii_PYR-1 HELMQ---------------ARLE-PSPGNSVTMTLSQWGEPVTVDKPAV
MSMEG_3070|M.smegmatis_MC2_155 HTLLQ---------------AQLE-PTPGNSVTMTLSDWGKQVNVTKPAA
MLBr_00557|M.leprae_Br4923 HQLAQ---------------IRIDNKSSGNSVQMTLSNWDEPVQVTKPQV
MAV_3367|M.avium_104 HQLVQ---------------ANLQ-KSSGNSVQVTLSNWGEQVQVTKPPV
TH_1009|M.thermoresistible__bu RDLVQ---------------AQLE-PDSGTTVTMTLSEWNKPVTVVKPEV
MAB_2806|M.abscessus_ATCC_1997 HALTK---------------ISVD-TSPGNTIEMSLSDWGKPVTVDKPAQ
Rv1368|M.tuberculosis_H37Rv STPA-----------PAANLVRMVIDKDQGNVDITLSNWGAPVTIPNPAG
Mb1403|M.bovis_AF2122/97 STPA-----------PAANLVRMVIDKDQGNVDITLSNWGAPVTIPNPAG
MMAR_2188|M.marinum_M QAPASSTAESPAPEPPAANLVRMVVDKGQGNVEITLSNWGVPVTIPNPTG
MUL_1773|M.ulcerans_Agy99 QAPASSTAESPAPEPPAANLVRMVVDKGQGNVEITLSNWGVPVTIPNPTG
: .: ::**.*. * : :*
Mflv_3724|M.gilvum_PYR-GCK --
Mvan_2692|M.vanbaalenii_PYR-1 --
MSMEG_3070|M.smegmatis_MC2_155 --
MLBr_00557|M.leprae_Br4923 S-
MAV_3367|M.avium_104 SS
TH_1009|M.thermoresistible__bu --
MAB_2806|M.abscessus_ATCC_1997 --
Rv1368|M.tuberculosis_H37Rv --
Mb1403|M.bovis_AF2122/97 --
MMAR_2188|M.marinum_M --
MUL_1773|M.ulcerans_Agy99 --