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M. tuberculosis H37Rv Rv2945c (lppX)

annotation: PROBABLE CONSERVED LIPOPROTEIN LPPX
coordinates: 3290624 - 3291325
length: 233

NDGKRAVTSAVLVVLGACLALWLSGCSSPKPDAEEQGVPVSPTASDPALLAEIRQSLDATKGLTSVHVAV
RTTGKVDSLLGITSADVDVRANPLAAKGVCTYNDEQGVPFRVQGDNISVKLFDDWSNLGSISELSTSRVL
DPAAGVTQLLSGVTNLQAQGTEVIDGISTTKITGTIPASSVKMLDPGAKSARPATVWIAQDGSHHLVRAS
IDLGSGSIQLTQSKWNEPVNVD*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv2945clppX-100% (233)PROBABLE CONSERVED LIPOPROTEIN LPPX
M. tuberculosis H37RvRv1411clprG2e-2130.17% (242) lipoprotein LprG
M. tuberculosis H37RvRv1270clprA3e-1929.71% (239) lipoprotein LprA

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2970clppX1e-130100.00% (233) lipoprotein LppX
M. gilvum PYR-GCKMflv_3724-5e-2229.96% (237) hypothetical protein Mflv_3724
M. leprae Br4923MLBr_00136lppX1e-10076.39% (233) putative lipoprotein
M. abscessus ATCC 19977MAB_2806-1e-2130.77% (221) lipoprotein LprG precursor (27 kDa lipoprotein)
M. marinum MMMAR_1763lppX6e-9272.10% (233) lipoprotein LppX
M. avium 104MAV_3367-9e-2434.48% (232) LprG protein
M. smegmatis MC2 155MSMEG_3070-1e-1528.40% (243) LprG protein
M. thermoresistible (build 8)TH_1009lprG2e-1630.00% (240) PROBABLE CONSERVED LIPOPROTEIN LPRG
M. ulcerans Agy99MUL_2006lppX4e-9272.10% (233) lipoprotein LppX
M. vanbaalenii PYR-1Mvan_2692-2e-1929.11% (237) hypothetical protein Mvan_2692

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3724|M.gilvum_PYR-GCK          MPPGRPAARSTRPDTRTLYDAGMQTR---------LLAIFAALFAAVALL
Mvan_2692|M.vanbaalenii_PYR-1       ----------------------MQTR---------LLAIFAALFAVVALV
MSMEG_3070|M.smegmatis_MC2_155      ----------------------MQTRPRFA-----VQSLFAILATAAALV
MAV_3367|M.avium_104                ----------------------MQTRRR-------LSAVFASLTLATALI
TH_1009|M.thermoresistible__bu      ----------------------MQTRFRHAGRTVPVRNLFALFALVALIV
MAB_2806|M.abscessus_ATCC_1997      ----------------------MRNRIR-----------LALIPVAVAAI
Rv2945c|M.tuberculosis_H37Rv        ----------------------MNDGKR------AVTSAVLVVLGACLAL
Mb2970c|M.bovis_AF2122/97           ----------------------MNDGKR------AVTSAVLVVLGACLAL
MLBr_00136|M.leprae_Br4923          ----------------------MNDRKW------VTSSVMLVTLSACLAL
MMAR_1763|M.marinum_M               ----------------------MNHRKP------AVISALLVALG--LVL
MUL_2006|M.ulcerans_Agy99           ----------------------MNHRKP------AVISALLVALG--LVL
                                                          *.               .         :

Mflv_3724|M.gilvum_PYR-GCK          --AGCSS--SSTEDSGK------DLPDPTTLLSESSETTRNQTSAHLTLS
Mvan_2692|M.vanbaalenii_PYR-1       --AGCSG--SSSKDSGK------ELPDAATLLQRSSETTKAQTSAHLNLS
MSMEG_3070|M.smegmatis_MC2_155      --AGCS---SSSETSDA------PLPDGAALLQESASKTKTQQSVHLLLT
MAV_3367|M.avium_104                --AGCS---SGSKQSGA------PLPDPTSLVKQSADATKNVKSVHLVLS
TH_1009|M.thermoresistible__bu      GVAGCSSGEDQADQSEQ------PTPDAATLLEEAAQTTRDLQSVRLDLT
MAB_2806|M.abscessus_ATCC_1997      ALAGCS----KTDKADP------NLPEAATLLSESAATTKTQTSTHIVLK
Rv2945c|M.tuberculosis_H37Rv        WLSGCSSPKPDAEEQGVPVSPTASDPALLAEIRQSLDATKGLTSVHVAVR
Mb2970c|M.bovis_AF2122/97           WLSGCSSPKPDAEEQGVPVSPTASDPALLAEIRQSLDATKGLTSVHVAVR
MLBr_00136|M.leprae_Br4923          GLSGCSSTKPDAQEQSSSSSPASSDPALTAEIKQSLETTKALSSVHVVVQ
MMAR_1763|M.marinum_M               WLSGCSSDKTQPEAQSSTTVP--ADPALMAEIEQSLDATKALTSAHLAIR
MUL_2006|M.ulcerans_Agy99           WLSGCSSDKTQPEAQSSTTVP--ADPALMAEIEQSLDATKALTSAHLAIR
                                      :***     ..            *   : : .:   *:   *.:: : 

Mflv_3724|M.gilvum_PYR-GCK          VQGQIAELPVEQLEGDLTQTPAVAAKGTANIIFLGQRLNDVEFVVSDGDL
Mvan_2692|M.vanbaalenii_PYR-1       VQGQIPDLPVESLEGDLTQSPAVAAKGTANIIFLGQRLNDVAFVVSDGDL
MSMEG_3070|M.smegmatis_MC2_155      VQGKVDGLPVEKLDGDLTNAPAVAAEGTADLIAFGQKIADAKFVIADGNL
MAV_3367|M.avium_104                IQGKISGLPIKTLTGDLTTTPATAAKGNATITLGGSDI-DANFVVVDGTL
TH_1009|M.thermoresistible__bu      VQGEIPELPIETLQGDLTNVPEVGATGTADIIMMGQRFEDVDFVVAEGNL
MAB_2806|M.abscessus_ATCC_1997      VTGDKPTLKLSDLTGDLTTKPAVAAKGTAKTGGL-----ELPFVVVDGEL
Rv2945c|M.tuberculosis_H37Rv        TTGKVDSLLGITSADVDVRANPLAAKGVCTYNDEQ----GVPFRVQGDNI
Mb2970c|M.bovis_AF2122/97           TTGKVDSLLGITSADVDVRANPLAAKGVCTYNDEQ----GVPFRVQGDNI
MLBr_00136|M.leprae_Br4923          TTGKVDALLGISNADVDVQANPLAVKGTCTYNDQP----GVPFRVLGDNI
MMAR_1763|M.marinum_M               TTGKVDSMLGISSADVNVQAKPLAAKGDCTYNGEA----GVPFRIKDDNI
MUL_2006|M.ulcerans_Agy99           TTGKVDSMLGISSADVNVQAKPLAAKGDCTYNGEA----GVPFRIKDDNI
                                      *.   :      .  .     .. * .             * :  . :

Mflv_3724|M.gilvum_PYR-GCK          WATITAGGSLSNFGPAADVYDVAAILDPNVGLANVLANFSN-PSADGRET
Mvan_2692|M.vanbaalenii_PYR-1       YAAITAGGALSNFGPASDVYDVAAILNPDVGLANVLANFSN-PTADGREE
MSMEG_3070|M.smegmatis_MC2_155      YAALTPGDPLSNYGAAANIYDVSAILNPDTGLANVLANFSD-ATADGRES
MAV_3367|M.avium_104                YATLTPN-KWSDFGKASDIYDVSVLLNPDNGLGNALANFSN-AKAEGRET
TH_1009|M.thermoresistible__bu      FAALAAG-DYIDFGPAADIYDVSAILNPDTGLANLLANFSDDATVEGRET
MAB_2806|M.abscessus_ATCC_1997      FAQLGSA--YSSMGPVKDVYDVGLILDPNKGLANLLANITG-AKSEKTET
Rv2945c|M.tuberculosis_H37Rv        SVKLFDD--WSNLGSISELS-TSRVLDPAAGVTQLLSGVTN-LQAQGTEV
Mb2970c|M.bovis_AF2122/97           SVKLFDD--WSNLGSISELS-TSRVLDPAAGVTQLLSGVTN-LQAQGTEV
MLBr_00136|M.leprae_Br4923          SVKLFDD--WSNLGSISDLS-TSHVLDPNTGITQVLSGVIN-LQAQGTEV
MMAR_1763|M.marinum_M               SVKLFDD--WSNLGSVSDLS-ASRVLDPINGVTKLLSGVNN-LQSQGNEV
MUL_2006|M.ulcerans_Agy99           SVKLFDD--WSNLGSVSDLS-ASRVLDPINGVTKLLSGVNN-LQSQGNEV
                                     . :       . *   ::  .. :*:*  *: : *:.. .    :  * 

Mflv_3724|M.gilvum_PYR-GCK          VEGTQTVRVTGEVSADAVNKIAPQIGATGPVPGTAWVAEEGDHKLMQVRL
Mvan_2692|M.vanbaalenii_PYR-1       VKGAQTVRVTGEVSADAVNKIAPQIAATGPVPGTAWITEDGDHELMQARL
MSMEG_3070|M.smegmatis_MC2_155      INGTEAVRVKGNVSADAVNKIAPALKADGPVPGTAWITED-DHTLLQAQL
MAV_3367|M.avium_104                INGQSTIRISGNVSADAVNKIMPQFNATQPVPSTVWVQETGDHQLVQANL
TH_1009|M.thermoresistible__bu      INGVRTLHVTGTVTPEAVNAIAPQIGAEAPVPAGAWIRADGARDLVQAQL
MAB_2806|M.abscessus_ATCC_1997      IDGVDSVLVTGTMSKDALNTFTGGTTLTADIPAKAWIQKDGNHALTKISV
Rv2945c|M.tuberculosis_H37Rv        IDGISTTKITGTIPASSVKMLDP--GAKSARPATVWIAQDGSHHLVRASI
Mb2970c|M.bovis_AF2122/97           IDGISTTKITGTIPASSVKMLDP--GAKSARPATVWIAQDGSHHLVRASI
MLBr_00136|M.leprae_Br4923          VDRIPTNKITGTVPTSSVKMLDP--KAKGSKLATVWIAQDGSHHLVRASI
MMAR_1763|M.marinum_M               INGIQTSKITGTLPTDSVKILDP--GARSPRPATVWIAQDGSHRLVRANV
MUL_2006|M.ulcerans_Agy99           INGIQTSKITGTLPTDSVKILDP--GARSPRPATVWIAQDGSHRLVRANV
                                    :.   :  :.* :. .::: :           . .*:     : * :  :

Mflv_3724|M.gilvum_PYR-GCK          EPSPGNSVTMTLSKWGEPVTVDKPAV--
Mvan_2692|M.vanbaalenii_PYR-1       EPSPGNSVTMTLSQWGEPVTVDKPAV--
MSMEG_3070|M.smegmatis_MC2_155      EPTPGNSVTMTLSDWGKQVNVTKPAA--
MAV_3367|M.avium_104                QKSSGNSVQVTLSNWGEQVQVTKPPVSS
TH_1009|M.thermoresistible__bu      EPDSGTTVTMTLSEWNKPVTVVKPEV--
MAB_2806|M.abscessus_ATCC_1997      DTSPGNTIEMSLSDWGKPVTVDKPAQ--
Rv2945c|M.tuberculosis_H37Rv        DLGSG-SIQLTQSKWNEPVNVD------
Mb2970c|M.bovis_AF2122/97           DLGSG-SIQLTQSKWNEPVNVD------
MLBr_00136|M.leprae_Br4923          DLGSG-SIQLTQSKWNEPVNTN------
MMAR_1763|M.marinum_M               DLGSG-AVEVTLSKWNEPVNVD------
MUL_2006|M.ulcerans_Agy99           DLGSG-AVEVTLSKWNEPVNVD------
                                    :  .* :: :: *.*.: * .