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M. tuberculosis H37Rv Rv1340 (rph)

annotation: ribonuclease PH
coordinates: 1506755 - 1507534
length: 259

VSKREDGRLDHELRPVIITRGFTENPAGSVLIEFGHTKVLCTASVTEGVPRWRKATGLGWLTAEYAMLPS
ATHSRSDRESVRGRLSGRTQEISRLIGRSLRACIDLAALGENTIAIDCDVLQADGGTRTAAITGAYVALA
DAVTYLSAAGKLSDPRPLSCAIAAVSVGVVDGRIRVDLPYEEDSRAEVDMNVVATDTGTLVEIQGTGEGA
TFARSTLDKLLDMALGACDTLFAAQRDALALPYPGVLPQGPPPPKAFGT
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv1340rph-100% (259)ribonuclease PH

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1375rph1e-14699.61% (259) ribonuclease PH
M. gilvum PYR-GCKMflv_2358rph1e-12484.23% (260) ribonuclease PH
M. leprae Br4923MLBr_01174rph1e-13289.19% (259) ribonuclease PH
M. abscessus ATCC 19977MAB_1484rph1e-12384.56% (259) ribonuclease PH
M. marinum MMMAR_4042rph1e-13791.89% (259) ribonuclease RphA
M. avium 104MAV_1557rph1e-13690.73% (259) ribonuclease PH
M. smegmatis MC2 155MSMEG_4901rph1e-12785.33% (259) ribonuclease PH
M. thermoresistible (build 8)TH_1015rphA1e-12585.00% (260) PROBABLE RIBONUCLEASE RPHA (RNase PH) (tRNA
M. ulcerans Agy99MUL_3908rph1e-13591.12% (259) ribonuclease PH
M. vanbaalenii PYR-1Mvan_4287rph1e-12585.77% (260) ribonuclease PH

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2358|M.gilvum_PYR-GCK          -----------------MSRREDGRLDDELRPVTITRGFTTHPAGSVLVE
Mvan_4287|M.vanbaalenii_PYR-1       -----------------MSRREDGRLDDELRPVTITRGFTTHPAGSVLVE
TH_1015|M.thermoresistible__bu      -----------------VSRREDGRLDDELRPVVITRGYTSHPAGSVLVE
MAB_1484|M.abscessus_ATCC_1997      -----------------MSRREDGRQDDELRPVTITRGFTSHPAGSVLIE
MSMEG_4901|M.smegmatis_MC2_155      -----------------MSRREDGRLDDELRPVVITRGFTSHPAGSVLVE
Rv1340|M.tuberculosis_H37Rv         -----------------MSKREDGRLDHELRPVIITRGFTENPAGSVLIE
Mb1375|M.bovis_AF2122/97            -----------------MSKREDGRLDHELRPVIITRGFTENPAGSVLIE
MLBr_01174|M.leprae_Br4923          -----------------MSTRADGRLDDELRAVVITRGFTEHPAGSVLIE
MAV_1557|M.avium_104                -----------------MTRREDGRLDDELRPLVITRGFTEHPAGSVLIE
MMAR_4042|M.marinum_M               MSGALGLVSVGRARVGVVSKREDGRRDDELRPVVITRGFTENPAGSVLIE
MUL_3908|M.ulcerans_Agy99           -----------------MSKREDGRRDDELRPVVITRGFTENPAGSVLIE
                                                     :: * *** *.***.: ****:* :******:*

Mflv_2358|M.gilvum_PYR-GCK          FGETRVMCTASVTEGVPRWRKGSGQGWLTAEYAMLPAATHDRSDRESVKG
Mvan_4287|M.vanbaalenii_PYR-1       FGQTRVMCTASVTEGVPRWRKGSGQGWLTAEYAMLPAATHERSGRESVKG
TH_1015|M.thermoresistible__bu      FGHTRVLCTASVLEGVPRWRKGSGQGWLTAEYAMLPAATHERSDRESVKG
MAB_1484|M.abscessus_ATCC_1997      FGQTRVMCTASATEGVPRWRKGSGLGWLTAEYAMLPASTHTRSDRESVKG
MSMEG_4901|M.smegmatis_MC2_155      FGQTRVMCTASVTEGVPRWRKGSGQGWLTAEYAMLPAATHDRSDRESVKG
Rv1340|M.tuberculosis_H37Rv         FGHTKVLCTASVTEGVPRWRKATGLGWLTAEYAMLPSATHSRSDRESVRG
Mb1375|M.bovis_AF2122/97            FGHTKVLCTASVTEGVPRWRKATGLGWLTAEYAMLPSATHSRSDRESVRG
MLBr_01174|M.leprae_Br4923          FGHTKVMCTASPTEGVPRWRKGSGKGWLTAEYAMLPSATHTRSERESVKG
MAV_1557|M.avium_104                FGHTKVMCTASVTEGVPRWRKGSGLGWLTAEYAMLPSATHTRSDRESVKG
MMAR_4042|M.marinum_M               FGRTKVMCTASVTEGVPRWRKGSGLGWLTAEYAMLPSATHTRSDRESVKG
MUL_3908|M.ulcerans_Agy99           FGRTKVMCTASVTEGVSRWRKGSGLGWLTAEYAMLPSATHTRSDRESVKG
                                    **.*:*:****  ***.****.:* ***********::** ** ****:*

Mflv_2358|M.gilvum_PYR-GCK          RVGGRTQEISRLVGRSLRACIDLAALGENTIAIDCDVLQADGGTRTAAIT
Mvan_4287|M.vanbaalenii_PYR-1       RVGGRTQEISRLVGRSLRACIDLAALGENTIAIDCDVLQADGGTRTAAIT
TH_1015|M.thermoresistible__bu      RLGGRTQEISRLIGRSLRACIDLNALGENTIAIDCDVLQADGGTRTAAIT
MAB_1484|M.abscessus_ATCC_1997      RVGGRTQEISRLIGRSLRACIDLSALGENTIAIDCDVLQADGGTRTAAIT
MSMEG_4901|M.smegmatis_MC2_155      RIGGRTQEISRLIGRSLRACIDLAALGENTIAIDCDVLQADGGTRTAAIT
Rv1340|M.tuberculosis_H37Rv         RLSGRTQEISRLIGRSLRACIDLAALGENTIAIDCDVLQADGGTRTAAIT
Mb1375|M.bovis_AF2122/97            RLSGRTQEISRLISRSLRACIDLAALGENTIAIDCDVLQADGGTRTAAIT
MLBr_01174|M.leprae_Br4923          RLSGRTQEISRLIGRSLRACIDLAALGENTIAVDCDVLQADGGTRTAAVT
MAV_1557|M.avium_104                RLSGRTQEISRLIGRSLRACIDLAALGENTIAVDCDVLQADGGTRTAAIT
MMAR_4042|M.marinum_M               RVGGRTQEISRLVGRSLRACIDLAALGENTIAVDCDVLQADGGTRTAAIT
MUL_3908|M.ulcerans_Agy99           RVGGRTQEISRLVGRSLRACIDLAALGENTIAVDCDVLQADGGTRTAAIT
                                    *:.*********:.********* ********:***************:*

Mflv_2358|M.gilvum_PYR-GCK          GAFVALSDAVTYLGAAGKLSDPRPLSCAIAAVSVGVVDGRVRVDLPYTED
Mvan_4287|M.vanbaalenii_PYR-1       GAYVALADAVTYLAAAGKLSDPRPLSCAIAAVSVGVVDGRIRVDLPYTED
TH_1015|M.thermoresistible__bu      GAYVALADAVTYLAAAEKLSDPWPLSCAIAAISVGVVDGRVRVDLPYSED
MAB_1484|M.abscessus_ATCC_1997      GAYVALADAVTYLAAHGKLADDEPLSCAIAAVSVGVVDGRVRVDLPYEED
MSMEG_4901|M.smegmatis_MC2_155      GAYVALSDAVTWLAAAGRLSDPRPLSCAIAAVSVGVVDGRVRVDLPYSED
Rv1340|M.tuberculosis_H37Rv         GAYVALADAVTYLSAAGKLSDPRPLSCAIAAVSVGVVDGRIRVDLPYEED
Mb1375|M.bovis_AF2122/97            GAYVALADAVTYLSAAGKLSDPRPLSCAIAAVSVGVVDGRIRVDLPYEED
MLBr_01174|M.leprae_Br4923          GAYVALADAVTYLSAAGRLLDPRPLSCAIAAVSVGVVDGRIRVDLSYEED
MAV_1557|M.avium_104                GAFVALADAVTYLSAAGKLSDPRPLSCAIAAVSVGVVDGRIRVDLPYEED
MMAR_4042|M.marinum_M               GAYVALADAVNYLAAAGKLSDPRPLSCAIAAVSVGVVDGRVRVDLPYEED
MUL_3908|M.ulcerans_Agy99           GAYVALADAVNYLAAAGKLSDPRPLSCAIAAVSVGVVDGRVRVDLPYEED
                                    **:***:***.:*.*  :* *  ********:********:****.* **

Mflv_2358|M.gilvum_PYR-GCK          SRAEVDMNVVATDTGTLVEIQGTGEGATFPRSTLDKMLDAAMAACDQLFE
Mvan_4287|M.vanbaalenii_PYR-1       SRAEVDMNVVATDTGTLVEIQGTGEGATFPRSTLDKMLDAAMAACDQLFE
TH_1015|M.thermoresistible__bu      ARAEVDMNVVATDTGTLVEVQGTGEGATFPRSTLDKMLDAALAACDQLFA
MAB_1484|M.abscessus_ATCC_1997      SRAEVDMNVVATDTGTLVEVQGTGEGATFARSTLDKLLDAAVGAADQLFV
MSMEG_4901|M.smegmatis_MC2_155      SRAEVDMNVVATDTGTLVEIQGTGEGATFPRSTLDKMLDAALGATEQLFV
Rv1340|M.tuberculosis_H37Rv         SRAEVDMNVVATDTGTLVEIQGTGEGATFARSTLDKLLDMALGACDTLFA
Mb1375|M.bovis_AF2122/97            SRAEVDMNVVATDTGTLVEIQGTGEGATFARSTLDKLLDMALGACDTLFA
MLBr_01174|M.leprae_Br4923          SRAEVDMNVIATDTGTLVEIQGTGEGATFPRSTLDKLLDMALGACDKLFV
MAV_1557|M.avium_104                ARAEVDMNVVATDTGTLVEVQGTGEGATFPRSTLDKLLDAALAACDKLFA
MMAR_4042|M.marinum_M               SRAEVDMNVVATDTGTLVEVQGTGEGATFPRSTLDKLLDMALGACDTLFA
MUL_3908|M.ulcerans_Agy99           SRAEVDMNVVATDTGTLVEVQGTGEGATFPRSTLDKLLDMALGACDTLFA
                                    :********:*********:*********.******:** *:.* : ** 

Mflv_2358|M.gilvum_PYR-GCK          IQRAALELPYPGTLPESAEPAKKAFGS
Mvan_4287|M.vanbaalenii_PYR-1       IQRAALELPYPGVLPEPGEPAKKAFGS
TH_1015|M.thermoresistible__bu      VQREALELPYPGVLPAPTSPPKKAFGS
MAB_1484|M.abscessus_ATCC_1997      LQKEALALPYPGVLP--DAPQKKAFGS
MSMEG_4901|M.smegmatis_MC2_155      LQREALDAPYPGVLPEGPAP-KKAFGS
Rv1340|M.tuberculosis_H37Rv         AQRDALALPYPGVLPQGPPP-PKAFGT
Mb1375|M.bovis_AF2122/97            AQRDALALPYPGVLPQGPPP-PKAFGT
MLBr_01174|M.leprae_Br4923          AQRDALALPYQGMSPEGPPP-PKAFGS
MAV_1557|M.avium_104                AQREALKLPYPGVLPEGPPP-PKVFGS
MMAR_4042|M.marinum_M               AQRDALALPYPGVLPEGPPP-SKAFGS
MUL_3908|M.ulcerans_Agy99           AQCDALALPYPGVLPEGPPP-SKAFGS
                                     *  **  ** *  *    *  *.**: