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M. tuberculosis H37Rv Rv1316c (ogt)

annotation: PROBABLE METHYLATED-DNA--PROTEIN-CYSTEINE METHYLTRANSFERASE OGT (6-O-methylguanine-DNA methyltransferase) (O-6-methylguanine-DNA-alkyltransferase)
coordinates: 1477134 - 1477631
length: 165

IHYRTIDSPIGPLTLAGHGSVLTNLRMLEQTYEPSRTHWTPDPGAFSGAVDQLNAYFAGELTEFDVELDL
RGTDFQQRVWKALLTIPYGETRSYGEIADQIGAPGAARAVGLANGHNPIAIIVPCHRVIGASGKLTGYGG
GINRKRALLELEKSRAPADLTLFD*

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. tuberculosis H37Rv Rv1316c ogt - 100% (165) PROBABLE METHYLATED-DNA--PROTEIN-CYSTEINE METHYLTRANSFERASE OGT (6-O-methylguanine-DNA methyltransferase) (O-6-methylguanine-DNA-alkyltransferase)

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb1349c ogt 1e-94 100.00% (165) methylated-DNA--protein-cysteine methyltransferase
M. gilvum PYR-GCK Mflv_2325 - 3e-53 66.20% (142) methylated-DNA--protein-cysteine methyltransferase
M. leprae Br4923 MLBr_01151 ogt 4e-73 78.18% (165) putative methylated-DNA-protein-cysteine methyltransferase
M. abscessus ATCC 19977 MAB_3012 - 2e-21 42.14% (140) methylated-DNA--protein-cysteine methyltransferase
M. marinum M MMAR_4082 ogt 5e-70 75.46% (163) methylated-DNA--protein-cysteine methyltransferase Ogt
M. avium 104 MAV_1536 - 5e-76 80.00% (165) methylated-DNA--protein-cysteine methyltransferase
M. smegmatis MC2 155 MSMEG_4928 - 9e-58 69.23% (156) methylated-DNA--protein-cysteine methyltransferase
M. thermoresistible (build 8) - - - - -
M. ulcerans Agy99 MUL_3946 ogt 4e-70 75.46% (163) methylated-DNA--protein-cysteine methyltransferase Ogt
M. vanbaalenii PYR-1 Mvan_4323 - 7e-60 65.85% (164) methylated-DNA--protein-cysteine methyltransferase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2325|M.gilvum_PYR-GCK          ----MQYRVMDSPVGPLTLAGSHGRLQHLRMVDQTYEPDRADWMRDD---
Mvan_4323|M.vanbaalenii_PYR-1       -MDNMRYRTMDSPVGLLTLAGSTGRLQHLRMVDQTYEPDRAGWEKDD---
Rv1316c|M.tuberculosis_H37Rv        ---MIHYRTIDSPIGPLTLAGHGSVLTNLRMLEQTYEPSRTHWTPDP---
Mb1349c|M.bovis_AF2122/97           ---MIHYRTIDSPIGPLTLAGHGSVLTNLRMLEQTYEPSRTHWTPDP---
MLBr_01151|M.leprae_Br4923          ---MIHCRSMDSPIGPLILAGHGSVLTNLQMVDQTYEPSRVGWLPEN---
MAV_1536|M.avium_104                ---MIEYRTVDSPIGLLTLAGRDPVLTNLRMVDQTYEPSRTGWTENP---
MMAR_4082|M.marinum_M               ---MTHYRIVDSPIGPLTLAGHDGVLTNLRMVDQTYEPSRVGWEVDD---
MUL_3946|M.ulcerans_Agy99           ---MTHYRIIDSPIGPLTLAGHDGVLTNLRMVDQTYEPSRVGWEVDD---
MSMEG_4928|M.smegmatis_MC2_155      MRRALKCRTVDSPVGPLTLAGRDGHLVHLRMEDQTYEPSRDGWEVDD---
MAB_3012|M.abscessus_ATCC_1997      -MSTVGHCFFDTAIGSCAIAWSDRGIVALQLPERDDAATLARIRRPAGSE
                                             .*:.:*   :*     :  *:: ::   .            

Mflv_2325|M.gilvum_PYR-GCK          ----TAFDAVIAQLQEYFAGERKDFALD-LELVGT-PFQRRVWEALLTIP
Mvan_4323|M.vanbaalenii_PYR-1       ----SAFPEAVMQLQEYFRGERREFDLD-LELAGT-AFQRRVWEALLTIP
Rv1316c|M.tuberculosis_H37Rv        ----GAFSGAVDQLNAYFAGELTEFDVE-LDLRGT-DFQQRVWKALLTIP
Mb1349c|M.bovis_AF2122/97           ----GAFSGAVDQLNAYFAGELTEFDVE-LDLRGT-DFQQRVWKALLTIP
MLBr_01151|M.leprae_Br4923          ----GAFAEAVSQLDAYFAGELTEFAIE-LDLCGT-EFQQRVWQALLTIP
MAV_1536|M.avium_104                ----RAFAGAVEQLGAYFAGELTEFDIE-LDLRGS-EFQRRVWRALQTIP
MMAR_4082|M.marinum_M               ----EAFADAVSQLDAYFAGERFDFDLA-LDLRGT-EFQRRVWRALLTIP
MUL_3946|M.ulcerans_Agy99           ----EAFADAVSQLDAYFAGERFDFDLA-LDLRGT-EFQRRVWQALLTIP
MSMEG_4928|M.smegmatis_MC2_155      ----SAFPEVVEQLAEYFAGERTDFELS-LDLVGT-AFQRTVWTALREIP
MAB_3012|M.abscessus_ATCC_1997      LAPPDFVAQAIDGIRRVLAGDDDDLQWARLDLDGTTDFDREVYAATRAIG
                                          .  .:  :   : *:  ::    *:* *:  *:: *: *   * 

Mflv_2325|M.gilvum_PYR-GCK          YGETRSYGEVARQIGAPGAFRAVGLANGRNPIGIIIPCHRVIGTNGSLTG
Mvan_4323|M.vanbaalenii_PYR-1       YGETRSYGQIAQQIDAPGAFRAVGLANGHNPIGIVVPCHRVIGANGSLTG
Rv1316c|M.tuberculosis_H37Rv        YGETRSYGEIADQIGAPGAARAVGLANGHNPIAIIVPCHRVIGASGKLTG
Mb1349c|M.bovis_AF2122/97           YGETRSYGEIADQIGAPGAARAVGLANGHNPIAIIVPCHRVIGASGKLTG
MLBr_01151|M.leprae_Br4923          YGETRSYGEIAEQVGAPGAARAVGLANSRNPIAIIVPCHRVIGASGQLIG
MAV_1536|M.avium_104                YGETRSYGEIAEQIGAPGAARAVGLANGHNPIAIVVPCHRVIGASGKLTG
MMAR_4082|M.marinum_M               YGETRSYGEIAERIGARGAARAVGLANGRNPVAVIVPCHRVIGASGGLTG
MUL_3946|M.ulcerans_Agy99           YGETRSYGEIAERIGARGAARAVGLANGRNPVAVVVPCHRVIGASGGLTG
MSMEG_4928|M.smegmatis_MC2_155      YGQTCSYGEIARKIGSPGASRAVGLANGHNPIGIIVPCHRVIGANGSLTG
MAB_3012|M.abscessus_ATCC_1997      PGRTRSYGEVAASVGEPGAAQAVGQSLGRNPIPLLVPCHRVLAADRSLHG
                                     *.* ***::*  :.  ** :*** : .:**: :::*****:.:.  * *

Mflv_2325|M.gilvum_PYR-GCK          YG--GGLAQ--IFRGLLLVTAC------R-------
Mvan_4323|M.vanbaalenii_PYR-1       YG--GGLDRKKMLLGMERKNSP------TIPTLFD-
Rv1316c|M.tuberculosis_H37Rv        YG--GGINRKRALLELEKSRAP------ADLTLFD-
Mb1349c|M.bovis_AF2122/97           YG--GGINRKRALLELEKSRAP------ADLTLFD-
MLBr_01151|M.leprae_Br4923          YG--GGLNRKLTLLELEKHQVL------TSLTLFD-
MAV_1536|M.avium_104                YG--GGLDRKQTLLALERRHSP------ASLTLFD-
MMAR_4082|M.marinum_M               YG--GGLDRKQALLELERACVPADLTVRADLTLFDC
MUL_3946|M.ulcerans_Agy99           YG--GGLDRKQALLELERACVPADLTVRADLTLFDC
MSMEG_4928|M.smegmatis_MC2_155      YG--GGLERKRMLLDLEKSRMA--------PALF--
MAB_3012|M.abscessus_ATCC_1997      FSAYGGVVTKRELLRLEHTPGF------DDPTLF--
                                    :.  **:     :  :

species	id	gene	e-value	identity (len)	annotation
M. tuberculosis H37Rv	Rv1316c	ogt	-	100% (165)	PROBABLE METHYLATED-DNA--PROTEIN-CYSTEINE METHYLTRANSFERASE OGT (6-O-methylguanine-DNA methyltransferase) (O-6-methylguanine-DNA-alkyltransferase)