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M. tuberculosis H37Rv Rv1285 (cysD)

annotation: sulfate adenylyltransferase subunit 2
coordinates: 1437909 - 1438907
length: 332

MAITINMVNPTGFIRYEDVEQEAMTSDVTVGPAPGQYQLSHLRLLEAEAIHVIREVAAEFERPVLLFSGG
KDSIVMLHLALKAFRPGRLPFPVMHVDTGHNFDEVIATRDELVAAAGVRLVVASVQDDIDAGRVVETIPS
RNPIQTVTLLRAIRENQFDAAFGGARRDEEKARAKERVFSFRDEFGQWDPKAQRPELWNLYNGRHHKGEH
IRVFPLSNWTEFDIWSYIGAEQVRLPSIYFAHRRKVFQRDGMLLAVHRHMQPRADEPVFEATVRFRTVGD
VTCTGCVESSASTVAEVIAETAVARLTERGATRADDRISEAGMEDRKRQGYF
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv1285cysD-100% (332)sulfate adenylyltransferase subunit 2
M. tuberculosis H37RvRv2392cysH4e-0626.04% (169) phosphoadenosine phosphosulfate reductase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1316cysD0.0100.00% (332) sulfate adenylyltransferase subunit 2
M. gilvum PYR-GCKMflv_2271-1e-15788.26% (298) sulfate adenylyltransferase subunit 2
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4181-1e-12370.26% (306) sulfate adenylyltransferase subunit 2
M. marinum MMMAR_4133cysD1e-16793.18% (308) sulfate adenylyltransferase subunit 2 CysD
M. avium 104MAV_1436cysD1e-16289.42% (312) sulfate adenylyltransferase subunit 2
M. smegmatis MC2 155MSMEG_4979cysD1e-15186.58% (298) sulfate adenylyltransferase subunit 2
M. thermoresistible (build 8)TH_2243cysD1e-15688.37% (301) PROBABLE SULFATE ADENYLYLTRANSFERASE SUBUNIT 2 CYSD
M. ulcerans Agy99MUL_3996cysD1e-16792.86% (308) sulfate adenylyltransferase subunit 2
M. vanbaalenii PYR-1Mvan_4423-1e-15785.44% (309) sulfate adenylyltransferase subunit 2

CLUSTAL 2.0.9 multiple sequence alignment


Rv1285|M.tuberculosis_H37Rv         MAITINMVNPTGFIRYEDVEQEAMTSDVTVGPAPGQYQLSHLRLLEAEAI
Mb1316|M.bovis_AF2122/97            MAITINMVNPTGFIRYEDVEQEAMTSDVTVGPAPGQYQLSHLRLLEAEAI
MMAR_4133|M.marinum_M               ----------------------MTTSGVTTGPAVGQYELSHLRSLEAEAM
MUL_3996|M.ulcerans_Agy99           ----------------------MTTSGVTTGPAVGQYELSHLRSLEAEAM
MAV_1436|M.avium_104                ------------------MPKEAMTADLQTAPAAGQYELSHLRSLEAEAI
Mflv_2271|M.gilvum_PYR-GCK          -----------------------MTATDELTHNAGRYELSHLRALEAEAI
Mvan_4423|M.vanbaalenii_PYR-1       -----------------------MTATDELTQNAGRYELSHLRALEAEAI
TH_2243|M.thermoresistible__bu      --------------MTATIPQASEGAPGSGAPEPRAYELSHLRALEAEAI
MSMEG_4979|M.smegmatis_MC2_155      ---------------------MTAVDSAPAQTRTGQYELSHLRALEAEAI
MAB_4181|M.abscessus_ATCC_1997      ------------------MPTSSDVLHPRGSSPADSYELSHLNALEAEAV
                                                                        *:****. *****:

Rv1285|M.tuberculosis_H37Rv         HVIREVAAEFERPVLLFSGGKDSIVMLHLALKAFRPGRLPFPVMHVDTGH
Mb1316|M.bovis_AF2122/97            HVIREVAAEFERPVLLFSGGKDSIVMLHLALKAFRPGRLPFPVMHVDTGH
MMAR_4133|M.marinum_M               HIIREVAAEFERPVLLFSGGKDSIVMLHLAIKAFRPGRLPFPVMHVDTGH
MUL_3996|M.ulcerans_Agy99           HIIREVAAEFERPVLLFSGGKDSIVMLHLAIKAFRPGRLPFPVMHVDTGH
MAV_1436|M.avium_104                HIIREVAAEFERPVLLFSGGKDSIVMLHLALRAFRPGRLPFPVMHVDTGH
Mflv_2271|M.gilvum_PYR-GCK          HIIREVAAEFERPVLLFSGGKDSIVMLHLAVKAFRPGRLPFPVMHVDTGH
Mvan_4423|M.vanbaalenii_PYR-1       HIIREVAAEFERPVLLFSGGKDSIVMLHLAIKAFRPGRLPFPVMHVDTGH
TH_2243|M.thermoresistible__bu      HIIREVAAEFERPVLLFSGGKDSIVMLHLAMKAFRPGRVPFPVMHVDTGH
MSMEG_4979|M.smegmatis_MC2_155      HIIREVAAEFERPVLLFSGGKDSIVMLHLAIKAFAPGRLPFPVMHVDTGH
MAB_4181|M.abscessus_ATCC_1997      YIFREVAATFERPVLLFSGGKDSVVMLHVAAKAFWPSPLPFPVMHIDTGH
                                    :::***** **************:****:* :** *. :******:****

Rv1285|M.tuberculosis_H37Rv         NFDEVIATRDELVAAAGVRLVVASVQDDIDAGRVVETI---PSRNPIQTV
Mb1316|M.bovis_AF2122/97            NFDEVIATRDELVAAAGVRLVVASVQDDIDAGRVVETI---PSRNPIQTV
MMAR_4133|M.marinum_M               NFDEVIATRDELVAASGVRLVVASVQDDIDAGRVVETF---PSRNPMQTV
MUL_3996|M.ulcerans_Agy99           NFDEVIATRDELVAASGVRLVVASVQDDIDAGRVVETF---PSRNSMQTV
MAV_1436|M.avium_104                NFDEVIATRDELVKQHGLRLVVASVQDDIDAGRVVEPK---QGRNPIQTV
Mflv_2271|M.gilvum_PYR-GCK          NFDEVLQARDELVAETGVRLVVAKVQDDIDAGRVVETI---PSRNPMQTF
Mvan_4423|M.vanbaalenii_PYR-1       NFEEVLAARDELVAESGVRLVVAKVQDDIDAGRVVETI---PSRNPMQTF
TH_2243|M.thermoresistible__bu      NFDEVLATRDELVAENNLRLVVAKVQDDIDAGRVVENG---PSRNPLQTV
MSMEG_4979|M.smegmatis_MC2_155      NFEEVIATRDALVEKHGLRLVVASVQDDIDAGRVVDNG---PSRNPLQTV
MAB_4181|M.abscessus_ATCC_1997      NFDEVIAFRDETVGRYNLRLEVGSVQDDIDSGAVVEETGPGATRNRLQTA
                                    **:**:  **  *   .:** *..******:* **:       ** :** 

Rv1285|M.tuberculosis_H37Rv         TLLRAIRENQFDAAFGGARRDEEKARAKERVFSFRDEFGQWDPKAQRPEL
Mb1316|M.bovis_AF2122/97            TLLRAIRENQFDAAFGGARRDEEKARAKERVFSFRDEFGQWDPKAQRPEL
MMAR_4133|M.marinum_M               TLLRAIRENRFDAAFGGARRDEEKARAKERVFSFRDEFGQWDPKAQRPEL
MUL_3996|M.ulcerans_Agy99           TLLRAIRENRFDAAFGGARRDEEKARAKERVFSFRDEFGQWDPKAQRPEL
MAV_1436|M.avium_104                TLLRAIRENKFDAAFGGARRDEEKARAKERVFSFRDEFGQWDPKAQRPEL
Mflv_2271|M.gilvum_PYR-GCK          TLLRAIRENKFDAAFGGARRDEEKARAKERVFSFRDEFGQWDPKNQRPEL
Mvan_4423|M.vanbaalenii_PYR-1       TLLRAIRENKFDAAFGGARRDEEKARAKERVFSFRDEFGQWDPKNQRPEL
TH_2243|M.thermoresistible__bu      TLLRAIRENKFDAAFGGARRDEEKARAKERVFSFRDEFGQWNPKAQRPEL
MSMEG_4979|M.smegmatis_MC2_155      TLLRGIRENKFDAAFGGARRDEEKARAKERVFSFRDEFGQWDPKAQRPEL
MAB_4181|M.abscessus_ATCC_1997      TLLRSINEHRFDAVFGGARRDEEKARAKERVFSFRDEFGQWDPRAQRPEL
                                    ****.*.*::***.***************************:*: *****

Rv1285|M.tuberculosis_H37Rv         WNLYNGRHHKGEHIRVFPLSNWTEFDIWSYIGAEQVRLPSIYFAHRRKVF
Mb1316|M.bovis_AF2122/97            WNLYNGRHHKGEHIRVFPLSNWTEFDIWSYIGAEQVRLPSIYFAHRRKVF
MMAR_4133|M.marinum_M               WNLYNGRHHKGEHIRVFPLSNWTEFDIWSYIGAEHITLPSIYFAHRRKVF
MUL_3996|M.ulcerans_Agy99           WNLYNGRHHKGEHIRVFPLSNWTEFDIWSYIGAEHITLPSIYFAHRRKVF
MAV_1436|M.avium_104                WNLYNGRHHKGEHIRVFPLSNWTEFDIWSYIGAENIALPSIYYAHRRKVF
Mflv_2271|M.gilvum_PYR-GCK          WNLYNGRHRKGEHIRAFPLSNWTEFDIWSYIGAEQIKLPSIYYAHERKVF
Mvan_4423|M.vanbaalenii_PYR-1       WNLYNGRHRKGEHIRAFPLSNWTEFDIWSYIGAEKIKLPSIYYAHQRKVF
TH_2243|M.thermoresistible__bu      WNLYNGRHHKGEHIRVFPLSNWTEFDIWSYIGAENITLPSIYYAHRRKVF
MSMEG_4979|M.smegmatis_MC2_155      WNIYNGRHRKGEHIRVFPLSNWTEYDIWAYIGAEDITLPSIYYAHQRKVF
MAB_4181|M.abscessus_ATCC_1997      WNIYNGRHRKGEHIRVFPLSNWTELDIWQYIESESIVLPSLYYAHQRNVV
                                    **:*****:******.******** *** ** :* : ***:*:**.*:*.

Rv1285|M.tuberculosis_H37Rv         QRDGMLLAVHRHMQPRADEPVFEATVRFRTVGDVTCTGCVESSASTVAEV
Mb1316|M.bovis_AF2122/97            QRDGMLLAVHRHMQPRADEPVFEATVRFRTVGDVTCTGCVESSASTVAEV
MMAR_4133|M.marinum_M               KRDGMLLAVDRHMQPGADEPVFEATVRFRTVGDVTCTGCVESEAATVAEV
MUL_3996|M.ulcerans_Agy99           KRDGMLLAVDRHMQPGADEPVFEATVRFRTVGDVTCTGCVESEAATVAEV
MAV_1436|M.avium_104                RRDGMLLAVDRNMQPNPDEPVFEATVRFRTVGDVTCTGCVESQAATVDEV
Mflv_2271|M.gilvum_PYR-GCK          ERDGMLLAVHKYLQPRKDEPIIEKTVRFRTVGDVTCTGCVESTAATVSEV
Mvan_4423|M.vanbaalenii_PYR-1       ERDGMLLAVHKHLQPRKDEPIIEKSVRFRTVGDVTCTGCVESTAATVSEV
TH_2243|M.thermoresistible__bu      RRDGMLLAVHRFMQPDPGEEVFETTVRFRTVGDVTCTGCVESTAATVDEV
MSMEG_4979|M.smegmatis_MC2_155      GRDGMLLAVHEFMQPRDGEEVFETSVRFRTVGDVTCTGCVESTAATVEQV
MAB_4181|M.abscessus_ATCC_1997      ERDGMLLAETRFLTLQPGEKLVEKSVRFRTIGDATCTGAVESVASTPSAV
                                     *******  . :    .* :.* :*****:**.****.*** *:*   *

Rv1285|M.tuberculosis_H37Rv         IAETAVARLTERGATRADDRISEAGMEDRKRQGYF
Mb1316|M.bovis_AF2122/97            IAETAVARLTERGATRADDRISEAGMEDRKRQGYF
MMAR_4133|M.marinum_M               IAETAVARLTERGATRADDRISESGMEDRKRQGYF
MUL_3996|M.ulcerans_Agy99           IAETAVARLTERGATRADDRISESGMEDRKRQGYF
MAV_1436|M.avium_104                IAETAVSRLTERGATRADDRISEAGMEDRKRQGYF
Mflv_2271|M.gilvum_PYR-GCK          IAETAISRLTERGATRADDRISEAGMEDRKREGYF
Mvan_4423|M.vanbaalenii_PYR-1       IAETAISRLTERGATRADDRISEAGMEDRKREGYF
TH_2243|M.thermoresistible__bu      IAETAVSRLTERGATRADDRISEAGMEDRKREGYF
MSMEG_4979|M.smegmatis_MC2_155      IAETAVSRLTERGATRADDRISEAGMEDRKREGYF
MAB_4181|M.abscessus_ATCC_1997      VEEVAATRITERGATRADDRISEAGMEDRKKEGYF
                                    : *.* :*:**************:******::***