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TTSGVTTGPAVGQYELSHLRSLEAEAMHIIREVAAEFERPVLLFSGGKDSIVMLHLAIKAFRPGRLPFPV MHVDTGHNFDEVIATRDELVAASGVRLVVASVQDDIDAGRVVETFPSRNPMQTVTLLRAIRENRFDAAFG GARRDEEKARAKERVFSFRDEFGQWDPKAQRPELWNLYNGRHHKGEHIRVFPLSNWTEFDIWSYIGAEHI TLPSIYFAHRRKVFKRDGMLLAVDRHMQPGADEPVFEATVRFRTVGDVTCTGCVESEAATVAEVIAETAV ARLTERGATRADDRISESGMEDRKRQGYF*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4133 | cysD | - | 100% (310) | sulfate adenylyltransferase subunit 2 CysD |
| M. marinum M | MMAR_3417 | cysH_1 | 1e-06 | 26.95% (167) | 3'-phosphoadenosine 5'-phosphosulfate reductase CysH_1 |
| M. marinum M | MMAR_3711 | cysH | 4e-05 | 25.30% (166) | 3'-phosphoadenosine 5'-phosphosulfate reductase CysH |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1316 | cysD | 1e-168 | 93.18% (308) | sulfate adenylyltransferase subunit 2 |
| M. gilvum PYR-GCK | Mflv_2271 | - | 1e-155 | 87.92% (298) | sulfate adenylyltransferase subunit 2 |
| M. tuberculosis H37Rv | Rv1285 | cysD | 1e-168 | 93.18% (308) | sulfate adenylyltransferase subunit 2 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4181 | - | 1e-124 | 72.58% (299) | sulfate adenylyltransferase subunit 2 |
| M. avium 104 | MAV_1436 | cysD | 1e-162 | 90.26% (308) | sulfate adenylyltransferase subunit 2 |
| M. smegmatis MC2 155 | MSMEG_4979 | cysD | 1e-151 | 84.84% (310) | sulfate adenylyltransferase subunit 2 |
| M. thermoresistible (build 8) | TH_2243 | cysD | 1e-155 | 88.70% (301) | PROBABLE SULFATE ADENYLYLTRANSFERASE SUBUNIT 2 CYSD |
| M. ulcerans Agy99 | MUL_3996 | cysD | 1e-179 | 99.68% (310) | sulfate adenylyltransferase subunit 2 |
| M. vanbaalenii PYR-1 | Mvan_4423 | - | 1e-155 | 88.59% (298) | sulfate adenylyltransferase subunit 2 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4133|M.marinum_M ----------------------MTTSGVTTGPAVGQYELSHLRSLEAEAM
MUL_3996|M.ulcerans_Agy99 ----------------------MTTSGVTTGPAVGQYELSHLRSLEAEAM
Mb1316|M.bovis_AF2122/97 MAITINMVNPTGFIRYEDVEQEAMTSDVTVGPAPGQYQLSHLRLLEAEAI
Rv1285|M.tuberculosis_H37Rv MAITINMVNPTGFIRYEDVEQEAMTSDVTVGPAPGQYQLSHLRLLEAEAI
MAV_1436|M.avium_104 ------------------MPKEAMTADLQTAPAAGQYELSHLRSLEAEAI
Mflv_2271|M.gilvum_PYR-GCK -----------------------MTATDELTHNAGRYELSHLRALEAEAI
Mvan_4423|M.vanbaalenii_PYR-1 -----------------------MTATDELTQNAGRYELSHLRALEAEAI
TH_2243|M.thermoresistible__bu --------------MTATIPQASEGAPGSGAPEPRAYELSHLRALEAEAI
MSMEG_4979|M.smegmatis_MC2_155 ---------------------MTAVDSAPAQTRTGQYELSHLRALEAEAI
MAB_4181|M.abscessus_ATCC_1997 ------------------MPTSSDVLHPRGSSPADSYELSHLNALEAEAV
*:****. *****:
MMAR_4133|M.marinum_M HIIREVAAEFERPVLLFSGGKDSIVMLHLAIKAFRPGRLPFPVMHVDTGH
MUL_3996|M.ulcerans_Agy99 HIIREVAAEFERPVLLFSGGKDSIVMLHLAIKAFRPGRLPFPVMHVDTGH
Mb1316|M.bovis_AF2122/97 HVIREVAAEFERPVLLFSGGKDSIVMLHLALKAFRPGRLPFPVMHVDTGH
Rv1285|M.tuberculosis_H37Rv HVIREVAAEFERPVLLFSGGKDSIVMLHLALKAFRPGRLPFPVMHVDTGH
MAV_1436|M.avium_104 HIIREVAAEFERPVLLFSGGKDSIVMLHLALRAFRPGRLPFPVMHVDTGH
Mflv_2271|M.gilvum_PYR-GCK HIIREVAAEFERPVLLFSGGKDSIVMLHLAVKAFRPGRLPFPVMHVDTGH
Mvan_4423|M.vanbaalenii_PYR-1 HIIREVAAEFERPVLLFSGGKDSIVMLHLAIKAFRPGRLPFPVMHVDTGH
TH_2243|M.thermoresistible__bu HIIREVAAEFERPVLLFSGGKDSIVMLHLAMKAFRPGRVPFPVMHVDTGH
MSMEG_4979|M.smegmatis_MC2_155 HIIREVAAEFERPVLLFSGGKDSIVMLHLAIKAFAPGRLPFPVMHVDTGH
MAB_4181|M.abscessus_ATCC_1997 YIFREVAATFERPVLLFSGGKDSVVMLHVAAKAFWPSPLPFPVMHIDTGH
:::***** **************:****:* :** *. :******:****
MMAR_4133|M.marinum_M NFDEVIATRDELVAASGVRLVVASVQDDIDAGRVVETF---PSRNPMQTV
MUL_3996|M.ulcerans_Agy99 NFDEVIATRDELVAASGVRLVVASVQDDIDAGRVVETF---PSRNSMQTV
Mb1316|M.bovis_AF2122/97 NFDEVIATRDELVAAAGVRLVVASVQDDIDAGRVVETI---PSRNPIQTV
Rv1285|M.tuberculosis_H37Rv NFDEVIATRDELVAAAGVRLVVASVQDDIDAGRVVETI---PSRNPIQTV
MAV_1436|M.avium_104 NFDEVIATRDELVKQHGLRLVVASVQDDIDAGRVVEPK---QGRNPIQTV
Mflv_2271|M.gilvum_PYR-GCK NFDEVLQARDELVAETGVRLVVAKVQDDIDAGRVVETI---PSRNPMQTF
Mvan_4423|M.vanbaalenii_PYR-1 NFEEVLAARDELVAESGVRLVVAKVQDDIDAGRVVETI---PSRNPMQTF
TH_2243|M.thermoresistible__bu NFDEVLATRDELVAENNLRLVVAKVQDDIDAGRVVENG---PSRNPLQTV
MSMEG_4979|M.smegmatis_MC2_155 NFEEVIATRDALVEKHGLRLVVASVQDDIDAGRVVDNG---PSRNPLQTV
MAB_4181|M.abscessus_ATCC_1997 NFDEVIAFRDETVGRYNLRLEVGSVQDDIDSGAVVEETGPGATRNRLQTA
**:**: ** * .:** *..******:* **: ** :**
MMAR_4133|M.marinum_M TLLRAIRENRFDAAFGGARRDEEKARAKERVFSFRDEFGQWDPKAQRPEL
MUL_3996|M.ulcerans_Agy99 TLLRAIRENRFDAAFGGARRDEEKARAKERVFSFRDEFGQWDPKAQRPEL
Mb1316|M.bovis_AF2122/97 TLLRAIRENQFDAAFGGARRDEEKARAKERVFSFRDEFGQWDPKAQRPEL
Rv1285|M.tuberculosis_H37Rv TLLRAIRENQFDAAFGGARRDEEKARAKERVFSFRDEFGQWDPKAQRPEL
MAV_1436|M.avium_104 TLLRAIRENKFDAAFGGARRDEEKARAKERVFSFRDEFGQWDPKAQRPEL
Mflv_2271|M.gilvum_PYR-GCK TLLRAIRENKFDAAFGGARRDEEKARAKERVFSFRDEFGQWDPKNQRPEL
Mvan_4423|M.vanbaalenii_PYR-1 TLLRAIRENKFDAAFGGARRDEEKARAKERVFSFRDEFGQWDPKNQRPEL
TH_2243|M.thermoresistible__bu TLLRAIRENKFDAAFGGARRDEEKARAKERVFSFRDEFGQWNPKAQRPEL
MSMEG_4979|M.smegmatis_MC2_155 TLLRGIRENKFDAAFGGARRDEEKARAKERVFSFRDEFGQWDPKAQRPEL
MAB_4181|M.abscessus_ATCC_1997 TLLRSINEHRFDAVFGGARRDEEKARAKERVFSFRDEFGQWDPRAQRPEL
****.*.*::***.***************************:*: *****
MMAR_4133|M.marinum_M WNLYNGRHHKGEHIRVFPLSNWTEFDIWSYIGAEHITLPSIYFAHRRKVF
MUL_3996|M.ulcerans_Agy99 WNLYNGRHHKGEHIRVFPLSNWTEFDIWSYIGAEHITLPSIYFAHRRKVF
Mb1316|M.bovis_AF2122/97 WNLYNGRHHKGEHIRVFPLSNWTEFDIWSYIGAEQVRLPSIYFAHRRKVF
Rv1285|M.tuberculosis_H37Rv WNLYNGRHHKGEHIRVFPLSNWTEFDIWSYIGAEQVRLPSIYFAHRRKVF
MAV_1436|M.avium_104 WNLYNGRHHKGEHIRVFPLSNWTEFDIWSYIGAENIALPSIYYAHRRKVF
Mflv_2271|M.gilvum_PYR-GCK WNLYNGRHRKGEHIRAFPLSNWTEFDIWSYIGAEQIKLPSIYYAHERKVF
Mvan_4423|M.vanbaalenii_PYR-1 WNLYNGRHRKGEHIRAFPLSNWTEFDIWSYIGAEKIKLPSIYYAHQRKVF
TH_2243|M.thermoresistible__bu WNLYNGRHHKGEHIRVFPLSNWTEFDIWSYIGAENITLPSIYYAHRRKVF
MSMEG_4979|M.smegmatis_MC2_155 WNIYNGRHRKGEHIRVFPLSNWTEYDIWAYIGAEDITLPSIYYAHQRKVF
MAB_4181|M.abscessus_ATCC_1997 WNIYNGRHRKGEHIRVFPLSNWTELDIWQYIESESIVLPSLYYAHQRNVV
**:*****:******.******** *** ** :* : ***:*:**.*:*.
MMAR_4133|M.marinum_M KRDGMLLAVDRHMQPGADEPVFEATVRFRTVGDVTCTGCVESEAATVAEV
MUL_3996|M.ulcerans_Agy99 KRDGMLLAVDRHMQPGADEPVFEATVRFRTVGDVTCTGCVESEAATVAEV
Mb1316|M.bovis_AF2122/97 QRDGMLLAVHRHMQPRADEPVFEATVRFRTVGDVTCTGCVESSASTVAEV
Rv1285|M.tuberculosis_H37Rv QRDGMLLAVHRHMQPRADEPVFEATVRFRTVGDVTCTGCVESSASTVAEV
MAV_1436|M.avium_104 RRDGMLLAVDRNMQPNPDEPVFEATVRFRTVGDVTCTGCVESQAATVDEV
Mflv_2271|M.gilvum_PYR-GCK ERDGMLLAVHKYLQPRKDEPIIEKTVRFRTVGDVTCTGCVESTAATVSEV
Mvan_4423|M.vanbaalenii_PYR-1 ERDGMLLAVHKHLQPRKDEPIIEKSVRFRTVGDVTCTGCVESTAATVSEV
TH_2243|M.thermoresistible__bu RRDGMLLAVHRFMQPDPGEEVFETTVRFRTVGDVTCTGCVESTAATVDEV
MSMEG_4979|M.smegmatis_MC2_155 GRDGMLLAVHEFMQPRDGEEVFETSVRFRTVGDVTCTGCVESTAATVEQV
MAB_4181|M.abscessus_ATCC_1997 ERDGMLLAETRFLTLQPGEKLVEKSVRFRTIGDATCTGAVESVASTPSAV
******* . : .* :.* :*****:**.****.*** *:* *
MMAR_4133|M.marinum_M IAETAVARLTERGATRADDRISESGMEDRKRQGYF
MUL_3996|M.ulcerans_Agy99 IAETAVARLTERGATRADDRISESGMEDRKRQGYF
Mb1316|M.bovis_AF2122/97 IAETAVARLTERGATRADDRISEAGMEDRKRQGYF
Rv1285|M.tuberculosis_H37Rv IAETAVARLTERGATRADDRISEAGMEDRKRQGYF
MAV_1436|M.avium_104 IAETAVSRLTERGATRADDRISEAGMEDRKRQGYF
Mflv_2271|M.gilvum_PYR-GCK IAETAISRLTERGATRADDRISEAGMEDRKREGYF
Mvan_4423|M.vanbaalenii_PYR-1 IAETAISRLTERGATRADDRISEAGMEDRKREGYF
TH_2243|M.thermoresistible__bu IAETAVSRLTERGATRADDRISEAGMEDRKREGYF
MSMEG_4979|M.smegmatis_MC2_155 IAETAVSRLTERGATRADDRISEAGMEDRKREGYF
MAB_4181|M.abscessus_ATCC_1997 VEEVAATRITERGATRADDRISEAGMEDRKKEGYF
: *.* :*:**************:******::***