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M. tuberculosis H37Rv Rv1213 (glgC)

annotation: glucose-1-phosphate adenylyltransferase
coordinates: 1355836 - 1357050
length: 404

MREVPHVLGIVLAGGEGKRLYPLTADRAKPAVPFGGAYRLIDFVLSNLVNARYLRICVLTQYKSHSLDRH
ISQNWRLSGLAGEYITPVPAQQRLGPRWYTGSADAIYQSLNLIYDEDPDYIVVFGADHVYRMDPEQMVRF
HIDSGAGATVAGIRVPRENATAFGCIDADDSGRIRSFVEKPLEPPGTPDDPDTTFVSMGNYIFTTKVLID
AIRADADDDHSDHDMGGDIVPRLVADGMAAVYDFSDNEVPGATDRDRAYWRDVGTLDAFYDAHMDLVSVH
PVFNLYNKRWPIRGESENLAPAKFVNGGSAQESVVGAGSIISAASVRNSVLSSNVVVDDGAIVEGSVIMP
GTRVGRGAVVRHAILDKNVVVGPGEMVGVDLEKDRERFAISAGGVVAVGKGVWI
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv1213glgC-100% (404)glucose-1-phosphate adenylyltransferase
M. tuberculosis H37RvRv3264cmanB2e-2527.87% (366) D-alpha-D-mannose-1-phosphate guanylyltransferase MANB

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1245glgC0.0100.00% (404) glucose-1-phosphate adenylyltransferase
M. gilvum PYR-GCKMflv_2193glgC0.090.84% (404) glucose-1-phosphate adenylyltransferase
M. leprae Br4923MLBr_01069glgC0.092.57% (404) glucose-1-phosphate adenylyltransferase
M. abscessus ATCC 19977MAB_1352glgC0.089.85% (404) glucose-1-phosphate adenylyltransferase
M. marinum MMMAR_4225glgC0.096.04% (404) glucose-1-phosphate adenylyltransferase GlgC
M. avium 104MAV_1358glgC0.096.98% (398) glucose-1-phosphate adenylyltransferase
M. smegmatis MC2 155MSMEG_5078glgC0.093.56% (404) glucose-1-phosphate adenylyltransferase
M. thermoresistible (build 8)TH_0549glgC0.091.71% (398) glucose-1-phosphate adenylyltransferase
M. ulcerans Agy99MUL_4526glgC0.095.54% (404) glucose-1-phosphate adenylyltransferase
M. vanbaalenii PYR-1Mvan_4503glgC0.092.08% (404) glucose-1-phosphate adenylyltransferase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2193|M.gilvum_PYR-GCK          MREAPHVLGIVLAGGEGKRLYPLTADRAKPAVPFGGGYRLIDFVLSNLVN
Mvan_4503|M.vanbaalenii_PYR-1       MREAPHVLGIVLAGGEGKRLYPLTADRAKPAVPFGGGYRLIDFVLSNLVN
MSMEG_5078|M.smegmatis_MC2_155      MRELPHVLGIVLAGGEGKRLYPLTADRAKPAVPFGGAYRLIDFVLSNLVN
Rv1213|M.tuberculosis_H37Rv         MREVPHVLGIVLAGGEGKRLYPLTADRAKPAVPFGGAYRLIDFVLSNLVN
Mb1245|M.bovis_AF2122/97            MREVPHVLGIVLAGGEGKRLYPLTADRAKPAVPFGGAYRLIDFVLSNLVN
MLBr_01069|M.leprae_Br4923          MREVPQVLGIVLAGGEGKRLYPLTADRAKPAVPFGGAYRLVDFVLSNLVN
MAV_1358|M.avium_104                ------MLGIVLAGGEGKRLYPLTADRAKPAVPFGGAYRLIDFVLSNLVN
MMAR_4225|M.marinum_M               MREAPHVLGIVLAGGEGKRLYPLTADRAKPAVPFGGAYRLIDFVLSNLVN
MUL_4526|M.ulcerans_Agy99           MREAPHVLGIVLAGGEGKRLYPLTADRAKPAVPFGGAYRLIDFVLSNLVN
TH_0549|M.thermoresistible__bu      ------VLGIVLAGGEGKRLYPLTADRAKPAVPFGGAYRLIDFVLSNLVN
MAB_1352|M.abscessus_ATCC_1997      MRASPHVLGIVLAGGEGKRLYPLTADRAKPAVPFGGAYRLIDFVLSNLVN
                                          :*****************************.***:*********

Mflv_2193|M.gilvum_PYR-GCK          ARFLRICVLTQYKSHSLDRHISQNWRLSGLAGEYITPVPAQQRLGPRWYT
Mvan_4503|M.vanbaalenii_PYR-1       ARFLRICVLTQYKSHSLDRHISQNWRLSGLAGEYITPVPAQQRLGPRWYT
MSMEG_5078|M.smegmatis_MC2_155      ARYLRICVLTQYKSHSLDRHISQNWRLSGLAGEYITPVPAQQRLGPRWYT
Rv1213|M.tuberculosis_H37Rv         ARYLRICVLTQYKSHSLDRHISQNWRLSGLAGEYITPVPAQQRLGPRWYT
Mb1245|M.bovis_AF2122/97            ARYLRICVLTQYKSHSLDRHISQNWRLSGLAGEYITPVPAQQRLGPRWYT
MLBr_01069|M.leprae_Br4923          ARYLRICVLTQYKSHSLDRHISQNWRLSGLAGEYITPVPAQQRFGPHWYT
MAV_1358|M.avium_104                ARYLRICVLTQYKSHSLDRHISQNWRLSGLAGEYITPVPAQQRLGPRWYT
MMAR_4225|M.marinum_M               ARYLRICVLTQYKSHSLDRHISQNWRLSGLAGEYITPVPAQQRLGPRWYT
MUL_4526|M.ulcerans_Agy99           ARYLRICVLTQYKSHSLDRHISQNWRLSGLAGEYITPVPAQQRLGPRWYT
TH_0549|M.thermoresistible__bu      ARFLRICVLTQYKSHSLDRHISQNWRLSGLAGEYITPVPAQQRLGPRWYT
MAB_1352|M.abscessus_ATCC_1997      ARFLRICVLTQYKSHSLDRHISQNWRLSGLAGEYITPVPAQQRLGPRWYT
                                    **:****************************************:**:***

Mflv_2193|M.gilvum_PYR-GCK          GSADAIYQSMNLIYDEDPDYIVIFGADHVYRMDPEQMVQQHIESGAGATV
Mvan_4503|M.vanbaalenii_PYR-1       GSADAIYQSMNLIYDEDPDYIVIFGADHVYRMDPEQMVQQHIESGAGATV
MSMEG_5078|M.smegmatis_MC2_155      GSADAIYQSLNLIYDEDPDYIIIFGADHVYRMDPEQMMQFHIESGAGATV
Rv1213|M.tuberculosis_H37Rv         GSADAIYQSLNLIYDEDPDYIVVFGADHVYRMDPEQMVRFHIDSGAGATV
Mb1245|M.bovis_AF2122/97            GSADAIYQSLNLIYDEDPDYIVVFGADHVYRMDPEQMVRFHIDSGAGATV
MLBr_01069|M.leprae_Br4923          GSADAIYQSLNLIYDEDPDYLVVFGADHVYRMDPEQMLRFHIGSGAGATV
MAV_1358|M.avium_104                GSADAIYQSLNLIYDEDPDYIVVFGADHVYRMDPEQMVRFHIDSGAGATV
MMAR_4225|M.marinum_M               GSADAIYQSLNLIYDEDPDYIVVFGADHVYRMDPEQMVRFHIDSGAGVTV
MUL_4526|M.ulcerans_Agy99           GSADAIYQSLNLIYDEDPDYIVVFGADHVYRMDPEQMVRFHIDSGAGVTV
TH_0549|M.thermoresistible__bu      GSADAIYQSMNLIYDEDPDYIVVFGADHVYRMDPEQMLRFHIESGAGATV
MAB_1352|M.abscessus_ATCC_1997      GSADAIHQSLNLIFDEDPEYIVVFGADHVYRMDPEQMLDFHIESGAAVTV
                                    ******:**:***:****:*:::**************:  ** ***..**

Mflv_2193|M.gilvum_PYR-GCK          AGIRVPRSEASAFGCIDADDSGRIRGWVEKPADPPGTPDDPEMTFASMGN
Mvan_4503|M.vanbaalenii_PYR-1       AGIRVPRAEASAFGCIDSDDSGRIRGFIEKPADPPGTPDDPEQTFVSMGN
MSMEG_5078|M.smegmatis_MC2_155      AGIRVPRSEASAFGCIDADESGRIREFIEKPADPPGTPDDPEQTFVSMGN
Rv1213|M.tuberculosis_H37Rv         AGIRVPRENATAFGCIDADDSGRIRSFVEKPLEPPGTPDDPDTTFVSMGN
Mb1245|M.bovis_AF2122/97            AGIRVPRENATAFGCIDADDSGRIRSFVEKPLEPPGTPDDPDTTFVSMGN
MLBr_01069|M.leprae_Br4923          AGIRVPRSDATAFGCIDADDSGRIRRFTEKPLKPPGTPDDPDKTFVSMGN
MAV_1358|M.avium_104                AGIRVPRSEATAFGCIDSDESGRIRKFVEKPLDPPGTPDDPETTFVSMGN
MMAR_4225|M.marinum_M               AGIRVPRADASAFGCIDADDAGTIRDFVEKPLEPPGTPDDPTSTFVSMGN
MUL_4526|M.ulcerans_Agy99           AGIRVPRADASAFGCIDADDAGTIRDFVEKPLEPPGTPDDPTSTFVSMGN
TH_0549|M.thermoresistible__bu      AGIRVPRKEATAFGVIDADESGRIRAFVEKPAEPPAVPDNPDEAFASMGN
MAB_1352|M.abscessus_ATCC_1997      AGIRVPRTEASAFGCIDADDTGRIREFVEKPANPPGTPDDPDAAFVSMGN
                                    ******* :*:*** **:*::* ** : *** .**..**:*  :*.****

Mflv_2193|M.gilvum_PYR-GCK          YIFTTKVLIDAIRADAEDDDSDHDMGGDIIPRLVADGMASVYDFNNNEVP
Mvan_4503|M.vanbaalenii_PYR-1       YIFTTKVLIDAIRADAEDDDSDHDMGGDIIPRLVADGMAAVYDFNDNEVP
MSMEG_5078|M.smegmatis_MC2_155      YIFTTKVLIDAIRADADDDHSDHDMGGDIIPRLVADGMAAVYDFKNNEVP
Rv1213|M.tuberculosis_H37Rv         YIFTTKVLIDAIRADADDDHSDHDMGGDIVPRLVADGMAAVYDFSDNEVP
Mb1245|M.bovis_AF2122/97            YIFTTKVLIDAIRADADDDHSDHDMGGDIVPRLVADGMAAVYDFSDNEVP
MLBr_01069|M.leprae_Br4923          YIFTTKVLVDAIRADADDDHSYHDMGGDILPRLVDGGMAAVYDFSQNEVP
MAV_1358|M.avium_104                YIFTTKVLIDAIRADADDDHSDHDMGGDIIPRLVDDGMAAVYDFSDNEVP
MMAR_4225|M.marinum_M               YVFTTKVLIDAIRADADDDHSDHDMGGDIIPRLVADGMAAVYDFSNNEVP
MUL_4526|M.ulcerans_Agy99           YVFTTKVLIDAIRADADDDHSDHDMGGDIIPRLVADGMAVVYDFSNNEVP
TH_0549|M.thermoresistible__bu      YIFTTKVLIDAIKADAEDDHSDHDMGGDIIPRLVEDGMAAVYDFNDNEVP
MAB_1352|M.abscessus_ATCC_1997      YIFTTKELIDVIRADADDDHSDHDMGGDIIPRLVADGRAAVYDFNTNLVP
                                    *:**** *:*.*:***:**.* *******:**** .* * ****. * **

Mflv_2193|M.gilvum_PYR-GCK          GATERDHGYWRDVGTLDAFYDAHMDLVSVHPIFNLYNKRWPIRGGAENLA
Mvan_4503|M.vanbaalenii_PYR-1       GATERDHGYWRDVGTLDAFYDAHMDLVSVHPVFNLYNKRWPIRGGAENLA
MSMEG_5078|M.smegmatis_MC2_155      GATERDHGYWRDVGTLDAFYDAHMDLVSVHPVFNLYNKRWPIRGESENLA
Rv1213|M.tuberculosis_H37Rv         GATDRDRAYWRDVGTLDAFYDAHMDLVSVHPVFNLYNKRWPIRGESENLA
Mb1245|M.bovis_AF2122/97            GATDRDRAYWRDVGTLDAFYDAHMDLVSVHPVFNLYNKRWPIRGESENLA
MLBr_01069|M.leprae_Br4923          GATDWDRAYWRDVGTLDAFYDAHMDLVSLRPVFNLYNKRWPIRGESENLA
MAV_1358|M.avium_104                GATDRDRGYWRDVGTLDAFYDAHMDLVSVHPVFNLYNKRWPIRGESENLA
MMAR_4225|M.marinum_M               GATDRDRAYWRDVGTLDAFYDAHMDLVSVHPVFNLYNKRWPIRGESENLA
MUL_4526|M.ulcerans_Agy99           GATDRDRAYWRDVGTLDAFYDAHMDLVSVHPVFNLYNKRWPIRGESENLA
TH_0549|M.thermoresistible__bu      GATERDHGYWRDVGTLDAFYDAHMDLVSVHPVFNLYNRRWPIRGATENLA
MAB_1352|M.abscessus_ATCC_1997      GATERDHAYWRDVGTLDAFYDAHMDLVSVHPVFNLYNRRWPIRGESENLA
                                    ***: *:.********************::*:*****:****** :****

Mflv_2193|M.gilvum_PYR-GCK          PAKFVNGGSAQESVVGAGSIISAASVRNSVLSSNVAIDDGAIVEGSVIMP
Mvan_4503|M.vanbaalenii_PYR-1       PAKFVNGGSAQESVVGAGSIISAASVRNSVLSSNVVIDDGAIVEGSVIMP
MSMEG_5078|M.smegmatis_MC2_155      PAKFVNGGSAQESVVGAGSIISAASVRNSVLSSNVVVDDGAIVEGSVLMP
Rv1213|M.tuberculosis_H37Rv         PAKFVNGGSAQESVVGAGSIISAASVRNSVLSSNVVVDDGAIVEGSVIMP
Mb1245|M.bovis_AF2122/97            PAKFVNGGSAQESVVGAGSIISAASVRNSVLSSNVVVDDGAIVEGSVIMP
MLBr_01069|M.leprae_Br4923          PAKFVNGGSVQESVVGAGSIISAASVRNSVLSSNVVVDNGAIVEGSVIMP
MAV_1358|M.avium_104                PAKFVNGGSAQESVVGAGSIISAASVRNSVLSSNVVVDDGAIVEGSVIMP
MMAR_4225|M.marinum_M               PAKFVNGGSAQESVVGAGSIISAASVRNSVLSSNVVVEDGAIVEGSVIMP
MUL_4526|M.ulcerans_Agy99           PAKFVNGGSAQESVVGAGSIISAASVRNSVLSSNVVVEDGAIVEGSVIMP
TH_0549|M.thermoresistible__bu      PAKFVNGGSAQESVVGAGSIISAASVRNSVLSSNVVIDDGAIVEGSVLMP
MAB_1352|M.abscessus_ATCC_1997      PAKFVNGGSAQESVVGAGSIVSAASVRNSVLSSNVVIDDGAVVEGSVLMP
                                    *********.**********:**************.:::**:*****:**

Mflv_2193|M.gilvum_PYR-GCK          GVRIGRGAVVRHAILDKNVVVGPGEMVGVDLDKDRERFTVSAGGVVAVGK
Mvan_4503|M.vanbaalenii_PYR-1       GARIGRGAVVRHAILDKNVVVGPGEMVGVDLDKDRERFSISAGGVVAVGK
MSMEG_5078|M.smegmatis_MC2_155      GVRIGRGAVVRHAILDKNVVVGPGEMVGVDLDKDRERFAISAGGVVAVGK
Rv1213|M.tuberculosis_H37Rv         GTRVGRGAVVRHAILDKNVVVGPGEMVGVDLEKDRERFAISAGGVVAVGK
Mb1245|M.bovis_AF2122/97            GTRVGRGAVVRHAILDKNVVVGPGEMVGVDLEKDRERFAISAGGVVAVGK
MLBr_01069|M.leprae_Br4923          GARVGRGAVIRHAILDKNVVVGPGEMVGVDPERDREHFAISAGGVVVVGK
MAV_1358|M.avium_104                GARVGRGAVVRHAILDKNVVVGPGEMVGVDLERDRERFAISAGGVVAVGK
MMAR_4225|M.marinum_M               GARVGRGAVVRHAILDKNVVVGPGEMVGVDLDKDRERFAISAGGVVAVGK
MUL_4526|M.ulcerans_Agy99           GARVGRDAVVRHAILDKNVVVGPGEMVGVDLDKDRERFAISAGGVVAVGK
TH_0549|M.thermoresistible__bu      GVRVGRGAVVRRSILDKNVVVGPGEMVGVDLEKDRERFAISAGGVVTVGK
MAB_1352|M.abscessus_ATCC_1997      GVRVGRGAVVRHAILDKNVVVGVGEQVGVDIERDRERFNVSAGGVVAVGK
                                    *.*:**.**:*::********* ** **** ::***:* :******.***

Mflv_2193|M.gilvum_PYR-GCK          GVWI
Mvan_4503|M.vanbaalenii_PYR-1       GVWI
MSMEG_5078|M.smegmatis_MC2_155      GVWI
Rv1213|M.tuberculosis_H37Rv         GVWI
Mb1245|M.bovis_AF2122/97            GVWI
MLBr_01069|M.leprae_Br4923          GVWI
MAV_1358|M.avium_104                GVWI
MMAR_4225|M.marinum_M               GVWI
MUL_4526|M.ulcerans_Agy99           GVWI
TH_0549|M.thermoresistible__bu      GVWI
MAB_1352|M.abscessus_ATCC_1997      GVWI
                                    ****