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M. tuberculosis H37Rv Rv1075c (-)

annotation: CONSERVED EXPORTED PROTEIN
coordinates: 1199426 - 1200370
length: 314

PRRSTIALATAGALASTGTAYLGARNLLVGQATHARTVIPKSFDAPPRADGVYTRGGGPVQRWRREVPFD
VHLMIFGDSTATGYGCASAEEVPGVLIARGLAEQTGKRIRLSTKAIVGATSKGVCGQVDAMFVVGPPPDA
AVIMIGANDITALNGIGPSAQRLADCVRRLRTRGAVVVVGTCPDLGVITAIPQPLRALAHTRGVRLARAQ
TAAVKAAGGVPVPLGHLLAPKFRAMPELMFSADRYHPSAPAYALAADLLFLALRDALTEKLDIPIHETPS
RPGTATLEPGHTRHSMMSRLRRPRPARAVPTGG*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv1075c--100% (314)CONSERVED EXPORTED PROTEIN

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1104c-1e-180100.00% (314) hypothetical protein Mb1104c
M. gilvum PYR-GCKMflv_2041-1e-11074.25% (268) GDSL family lipase
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_1193c-3e-9862.38% (303) hypothetical protein MAB_1193c
M. marinum MMMAR_4392-1e-13576.18% (319) hypothetical protein MMAR_4392
M. avium 104MAV_1199-1e-13176.45% (310) hypothetical protein MAV_1199
M. smegmatis MC2 155MSMEG_5272-1e-10868.21% (302) hypothetical protein MSMEG_5272
M. thermoresistible (build 8)TH_1369-4e-6276.35% (148) CONSERVED EXPORTED PROTEIN
M. ulcerans Agy99MUL_0206-1e-11582.38% (244) hypothetical protein MUL_0206
M. vanbaalenii PYR-1Mvan_4676-1e-10875.09% (265) GDSL family lipase

CLUSTAL 2.0.9 multiple sequence alignment


MAB_1193c|M.abscessus_ATCC_199      MSILATRRRTIWAALSTGAAGAAMGTGVWGAYSFLNAQARQVRRVIPKTH
TH_1369|M.thermoresistible__bu      --------------------------------------------------
Mflv_2041|M.gilvum_PYR-GCK          MGIPR-RRSTV--ALAAAATLASTGTAYVGARNLLTGQADQARQIIPKAW
Mvan_4676|M.vanbaalenii_PYR-1       MGIRA-SRRSV--ALAAAATLASTGTAYVGARNLLSGQADQARRVIPKSW
MSMEG_5272|M.smegmatis_MC2_155      MGTRAPRRSTV--ALAAAATLASTGSAVIGARNLLNGQAAQARRTIPKAW
Rv1075c|M.tuberculosis_H37Rv        ----MPRRSTI--ALATAGALASTGTAYLGARNLLVGQATHARTVIPKSF
Mb1104c|M.bovis_AF2122/97           ----MPRRSTI--ALATAGALASTGTAYLGARNLLVGQATHARTVIPKSF
MAV_1199|M.avium_104                MTIRVPRRSAI--ALATAGALASTGTAYLGARSLLVGQATHARTVIPKSW
MMAR_4392|M.marinum_M               ----MPRRSTI--ALATAGALASTGTAYLGARNLLVGQATHARTIIPKAW
MUL_0206|M.ulcerans_Agy99           ----MPRRSTI--ALATAGALASTGTAYLGARNLLVGQATHARTIIPKAW
                                                                                      

MAB_1193c|M.abscessus_ATCC_199      DAPPVADGVYERGGGPVTRYTRGVQYDLHLAIFGDSTATGYGCHIPDEVP
TH_1369|M.thermoresistible__bu      --------VYSPDGGPVQPWNRDVPFDLHLMVFGDSTATGYGCREADEVP
Mflv_2041|M.gilvum_PYR-GCK          DIPPRADGVYSPGGGPVERWHRGVPFDLHLMIFGDSTATGYGCTVADEVP
Mvan_4676|M.vanbaalenii_PYR-1       DIPPRADGVYAPGGGPVERWHRGVPFDLHLMIFGDSTATGYGCAAADEVP
MSMEG_5272|M.smegmatis_MC2_155      AIPPRADGVYSPGGGPVERWERGVPFDLHLMIFGDSTATGYGCHSADEVP
Rv1075c|M.tuberculosis_H37Rv        DAPPRADGVYTRGGGPVQRWRREVPFDVHLMIFGDSTATGYGCASAEEVP
Mb1104c|M.bovis_AF2122/97           DAPPRADGVYTRGGGPVQRWRREVPFDVHLMIFGDSTATGYGCASAEEVP
MAV_1199|M.avium_104                DIPPRADGVYTRGGGPVQRWHRGMAVDLHLMIFGDSTAAGYGCMCADEVP
MMAR_4392|M.marinum_M               DVPPRADGVYSRGGGPVQRWRRGTPFDLHLMMFGDSTACGYGCGSPEEVP
MUL_0206|M.ulcerans_Agy99           DVPPRADGVYSRGGGPVQRWRRGTPFDLHLMMFGDSTACGYGCGSPEEVP
                                            **  .****  : *    *:** :****** ****  .:***

MAB_1193c|M.abscessus_ATCC_199      GVLLARGLAEESGKRIRLSTKAISGATSKGLAAQIDAMSIIGPPPDAAVI
TH_1369|M.thermoresistible__bu      GVLLARALASASGKRVRLSTKAIVGATSKGLQGQIDAMFVADQPPDAAVI
Mflv_2041|M.gilvum_PYR-GCK          GVLIARGLAEESGKRIRLSTKAIVGATSKGLSGQIDAMYVAGPPPDAAVI
Mvan_4676|M.vanbaalenii_PYR-1       GVLIARGLAEESGLRIRLSTKAIVGATSKGLSGQIDAMFVAGAPPDAAVI
MSMEG_5272|M.smegmatis_MC2_155      GVLLARGVAEQFGQRIRLSTKAIVGATSKGLSGQIDAMFVAGPPPDAAVI
Rv1075c|M.tuberculosis_H37Rv        GVLIARGLAEQTGKRIRLSTKAIVGATSKGVCGQVDAMFVVGPPPDAAVI
Mb1104c|M.bovis_AF2122/97           GVLIARGLAEQTGKRIRLSTKAIVGATSKGVCGQVDAMFVVGPPPDAAVI
MAV_1199|M.avium_104                GVRIARGLAEQTGKRIRLSTKAIVGATSKGVCGQVDAMFVAGPPPDVAVI
MMAR_4392|M.marinum_M               GVVMARKLAEQTGKRVRLSTKALVGATSKGVCGQVDAMFVAGPPPDAAII
MUL_0206|M.ulcerans_Agy99           GVVMARKLAEQTGKRVRLSTKALVGATSKGVCGQVDAMFVARPPPDATII
                                    ** :** :*.  * *:******: ******: .*:*** :   ***.::*

MAB_1193c|M.abscessus_ATCC_199      MIGANDVTSLNAVRASAQRLGDAVRRLRAAGSVVVVGTCPDFGVITAIPQ
TH_1369|M.thermoresistible__bu      MIGANDVTRLNGIRPSAQRLGAGVRRLREAGAVVVVGTCPDFGVVTAIPQ
Mflv_2041|M.gilvum_PYR-GCK          MIGANDITKPNGIGPSARRLGRAVRRLRGSDAVVVVGTCPDFGVITAIPQ
Mvan_4676|M.vanbaalenii_PYR-1       MIGANDITKPNGIGPSARRLGRAVRRLRGSDAVVVVGTCPDFGVITAIPQ
MSMEG_5272|M.smegmatis_MC2_155      MIGANDITKPNGIGPSARRLGAGVSRLRSAGAAVVVGTCPDFGVITAIPQ
Rv1075c|M.tuberculosis_H37Rv        MIGANDITALNGIGPSAQRLADCVRRLRTRGAVVVVGTCPDLGVITAIPQ
Mb1104c|M.bovis_AF2122/97           MIGANDITALNGIGPSAQRLADCVRRLRTRGAVVVVGTCPDLGVITAIPQ
MAV_1199|M.avium_104                MVGANDVTALNGVSQSAHRLGLCVRKLRNRGAVVIVGTCPDLGFISAIPQ
MMAR_4392|M.marinum_M               IIGANDITALNGIGPSAERLGSVVRKLRARGAIVVVGTCPDFSVITAIPQ
MUL_0206|M.ulcerans_Agy99           IIGANDMTALNGIGPSTERLGSVVRKLRARGAIVVVGTCPDFSVITAIPQ
                                    ::****:*  *.:  *:.**.  * :**  .: *:******:..::****

MAB_1193c|M.abscessus_ATCC_199      PLRAVVRSRGLRLAHFQAAAVRATGGVPVPLADLLAPEFLQAPEEMFADD
TH_1369|M.thermoresistible__bu      PLRSVARXX-----------------------------------------
Mflv_2041|M.gilvum_PYR-GCK          PLRWVARSRGLRLAHAQAAAVRAAGGVPVPFSDLLAPHFYKTPELLFSPD
Mvan_4676|M.vanbaalenii_PYR-1       PLRWVARSRGLRLARAQAAAVRAAGGVPVPFSDLLAPHFYKTPELLFSPD
MSMEG_5272|M.smegmatis_MC2_155      PLRWYARSRGLRLARAQAHAVRAAGGVPVPFSDLLTPEFHKTPELLFSED
Rv1075c|M.tuberculosis_H37Rv        PLRALAHTRGVRLARAQTAAVKAAGGVPVPLGHLLAPKFRAMPELMFSAD
Mb1104c|M.bovis_AF2122/97           PLRALAHTRGVRLARAQTAAVKAAGGVPVPLGHLLAPKFRAMPELMFSAD
MAV_1199|M.avium_104                PLRSLAHERCLQLARAQTATVRAAGGVPVPLAQLMAPQFRATPEAMFSAD
MMAR_4392|M.marinum_M               PLRSLAHTRGSQLARAQTAAVKAAGGVPVPLANLLARQFRAEPERMFSAD
MUL_0206|M.ulcerans_Agy99           PLRSLANTRGSQLARAQTAAVKAAGGVPVPLANLLARQFRAEPERMFSAD
                                    ***  ..                                           

MAB_1193c|M.abscessus_ATCC_199      HYHPSAAGYALAARLLLPAVAHALGEWTGGPIPDLPWVSAAAESQTMSAR
TH_1369|M.thermoresistible__bu      ------------------------XAWTR---------------------
Mflv_2041|M.gilvum_PYR-GCK          MFHPSAAGYELAATQLLPALCEELGEFITGEPLAEALESRTGEGTSLLSR
Mvan_4676|M.vanbaalenii_PYR-1       MFHPSAAGYELAAKQLLPALGNALGAFVTEDSAEAALESRTGEDGSLLGR
MSMEG_5272|M.smegmatis_MC2_155      MFHPSAAGYALAASQLLPALCNALGQWDGDD----ALETGAADTSSLWSR
Rv1075c|M.tuberculosis_H37Rv        RYHPSAPAYALAADLLFLALRDALTEKLDIPIHETPSRPGTATLEPGHTR
Mb1104c|M.bovis_AF2122/97           RYHPSAPAYALAADLLFLALRDALTEKLDIPIHETPSRPGTATLEPGHTR
MAV_1199|M.avium_104                GYHPSAPAYALAADALLLALCEALGEQVERPPLNQPVPSAQPVLGQRHTR
MMAR_4392|M.marinum_M               RYHPSATAYALAADQLLLSLRDALREKIGSAMLPVPSRPSFRTSSQERSR
MUL_0206|M.ulcerans_Agy99           -LDITHPQRRTPWRPISRSSVCAMRYAKRSGAQCFPCRRGLASAPAARSV
                                                                                      

MAB_1193c|M.abscessus_ATCC_199      LRVLSRIWRRNATEIATSITEPADRPDNLPVASLH
TH_1369|M.thermoresistible__bu      -----------------------------------
Mflv_2041|M.gilvum_PYR-GCK          VSGLTRLWRR-STGVPAPIVVAAG-----------
Mvan_4676|M.vanbaalenii_PYR-1       LGGLSRLWRR-STGVPAPIVVAAG-----------
MSMEG_5272|M.smegmatis_MC2_155      LGAMSRLWRR-STGVPAPVVAAAS-----------
Rv1075c|M.tuberculosis_H37Rv        HSMMSRLRRPRPARAVPTGG---------------
Mb1104c|M.bovis_AF2122/97           HSMMSRLRRPRPARAVPTGG---------------
MAV_1199|M.avium_104                SSVMSRLWRRPAPGAAPSSCPEVGSD---------
MMAR_4392|M.marinum_M               GAIVTRLWRRPVPVVGGPVAIPASG----------
MUL_0206|M.ulcerans_Agy99           PGAPS------SPGCGGARSRWLVDPS--------